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Mcpherson, CA

Alan J. Mcpherson, Chatsworth, CA US

Patent application number	Description	Published
20090074213	APPARATUS AND METHOD FOR DOWN CONVERTING MULTICHANNEL PROGRAMS TO DUAL CHANNEL PROGRAMS USING A SMART COEFFICIENT GENERATOR - An apparatus for recording a multichannel program includes an audio converter adapted to convert said multichannel program at least partially into a modified program requiring less channels than said multichannel program. The audio converter including control elements used to modify the conversion process used to generate said modified program. A coefficient generator coupled to said converter to generate a coefficient indicative of the operation of said controls. A mixer is arranged to mix the coefficient with program data. A recorder is arranged to record the mixed data on a medium, whereby the medium can be played either using a multichannel player device or a reduced channel player device by using said coefficient.	03-19-2009

Andrew Mcpherson, San Diego, CA US

Patent application number	Description	Published
20090275569	Benzotriazine Inhibitors of Kinases - The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.	11-05-2009
20110212077	BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES - The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases.	09-01-2011
20110294796	BENZOTRIAZINE INHIBITORS OF KINASES - The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.	12-01-2011

Dale S. Mcpherson, Burbank, CA US

Patent application number	Description	Published
20110073479	Multi-Step Release Method for Electrochemically Fabricated Structures - Multi-layer structures are electrochemically fabricated from at least one structural material (e.g. nickel), that is configured to define a desired structure and which may be attached to a substrate, and from at least one sacrificial material (e.g. copper) that surrounds the desired structure. After structure formation, the sacrificial material is removed by a multi-stage etching operation. In some embodiments sacrificial material to be removed may be located within passages or the like on a substrate or within an add-on component. The multi-stage etching operations may be separated by intermediate post processing activities, they may be separated by cleaning operations, or barrier material removal operations, or the like. Barriers may be fixed in position by contact with structural material or with a substrate or they may be solely fixed in position by sacrificial material and are thus free to be removed after all retaining sacrificial material is etched.	03-31-2011

Donald Martin Mcpherson, Oakland, CA US

Patent application number	Description	Published
20110037200	Method of producing a cementitious sheet-form material having a high level of glass aggregate and a solid surface - A method of producing a sheet-form material having an exposed solid surface comprises pre-mixing cement with at least one pozzolan to provide a cement/pozzolan mixture with a high pozzolan to cement ratio, adding to the cement/pozzolan mixture an aqueous solution comprised of water and a high range water reducer to produce a cement/pozzolan dough-like substance, adding and mixing a sufficient quantity of glass aggregate to said cement/pozzolan dough-like substance to produce a moldable composition, wherein, after adding and mixing in the glass aggregate, the pozzolan is present in the composition at about 5% to about 20% by weight, the cement is present in the composition at about 3% to about 20% by weight, and the aggregate glass is by weight a relatively high percentage of the composition. The moldable composition is placed into a mold and vibrated, and is allowed to cure.	02-17-2011
20110290154	CEMENTITIOUS COMPOSITION INCORPORATING HIGH LEVELS OF GLASS AGGREGATE FOR PRODUCING SOLID SURFACES - A cementitious composition for high density, low porosity sheet-form building materials having solid surfaces is comprised of cement, pozzolans, and a high percentage of fine and/or coarse glass aggregate.	12-01-2011

Edward J. Mcpherson, Los Angeles, CA US

Patent application number	Description	Published
20120179270	LOW STRESS MULTIPLE FIXATION ACETABULAR COMPONENT - The disclosure relates to revision hip surgery or total hip arthroplasty situations in which it is difficult for a surgeon to secure or fix an acetabular cup or shell to the bone due, for whatever reason, to bone loss or other bone deficiency. The system may comprise a plurality of fasteners and an acetabular cup or shell having a plurality of openings to thereby allow the plurality of fasteners to be inserted at diverging angles to create multiple fixation points to distribute load and secure the shell to available bone. The system may also include a bearing insert for receiving a femoral head component and a plurality of spacers for creating a cement mantle.	07-12-2012

John Ai Mcpherson, San Jose, CA US

Patent application number	Description	Published
20080222117	EFFICIENT MULTIFACETED SEARCH IN INFORMATION RETRIEVAL SYSTEMS - A method and system for querying multifaceted information. An inverted index is constructed to include unique indexed tokens associated with posting lists of one or more documents. An indexed token is either a facet token included in a document as an annotation or a path prefix of the facet token. The annotation indicates a path within a tree structure representing a facet that includes the document. The tree structure includes nodes representing categories of documents. A query is received that includes constraints on documents. The constraints are associated with indexed tokens and corresponding posting lists. An execution of the query includes identifying the corresponding posting lists by utilizing the constraints and the inverted index and intersecting the posting lists to obtain a query result.	09-11-2008

Kimra Mcpherson, San Francisco, CA US

Patent application number	Description	Published
20120079517	VIEWERSHIP-BASED SERVICES - A method, system, and computer program product containing instructions to provide viewership-based services. In response to a request to participate in a service transaction by a user of a service, a viewership status of the user is determined with respect to an episode of a series of episodes. The service transaction is modified to accommodate the viewership status of the user. Modifying the service transaction may include providing content related to a first episode in the series if the viewership status indicates the user has viewed the first episode and withholding content related to a second episode in the series if the viewership status indicates that the user has not viewed the second episode. Modifying the service transaction may include writing a post by the user to a collection of posts that is accessible only by users having a given viewership status.	03-29-2012

Paul Mcpherson, Encinitas, CA US

Patent application number	Description	Published
20110174062	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of cytochrome c and insulin-like growth factor IA as diagnostic and prognostic biomarkers in renal injuries.	07-21-2011
20110195429	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of soluble p-selectin, protein NOV homolog, soluble epidermal growth factor receptor, netrin-4, haptoglobin, heat shock protein beta-1, alpha-1-antitrypsin, leukocyte elastase, soluble tumor necrosis factor receptor superfamily member 6, soluble tumor necrosis factor ligand superfamily member 6, soluble intercellular adhesion molecule 2, active caspase-3, and soluble platelet endothelial cell adhesion molecule as diagnostic and prognostic biomarkers in renal injuries.	08-11-2011
20110201038	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Cytoplasmic aspartate aminotransferase, soluble Tumor necrosis factor receptor superfamily member 5, soluble CD40 Ligand, soluble C-X-C Motif chemokine 16, S100-A12, Eotaxin, soluble E-selectin, Fibronectin, Granulocyte colony-stimulating factor, Granulocyte-macrophage colony-stimulating factor, Heparin-binding growth factor 2, soluble Hepatocyte growth factor receptor, Interleukin-1 receptor antagonist, Interleukin-1 beta, Interleukin-10, Interleukin-15, Interleukin-3, Myeloperoxidase, Nidogen-1, soluble Oxidized low-density lipoprotein receptor 1, Pappalysin-1, soluble P-selectin glycoprotein ligand 1, Antileukoproteinase, soluble Kit ligand, Tissue inhibitor of metalloproteinase 1, Tissue inhibitor of metalloproteinase 2, soluble Tumor necrosis factor, soluble Vascular cell adhesion molecule 1, and Vascular endothelial growth factor A as diagnostic and prognostic biomarkers in renal injuries.	08-18-2011
20110207161	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of soluble CD44 antigen, Angiopoietin-1, soluble Angiopoietin-1 receptor, C—X—C chemokine motif 5, soluble Endoglin, soluble Tumor-associated calcium signal transducer 1, Erythropoietin, soluble Fractalkine, Heme oxygenase 1, soluble Interleukin-1 receptor type II, soluble Interleukin-6 receptor subunit-alpha, Lymphotactin, Lymphotoxin-alpha, Stromelysin-1, C—C motif chemokine 22, C—C motif chemokine 5, and Thrombospondin-1 as diagnostic and prognostic biomarkers in renal injuries.	08-25-2011
20110229915	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Epidermal growth factor, Complement C3, Interleukin-4, Interleukin-1 alpha, Tubulointerstitial nephritis antigen, Transforming growth factor beta-1, Bone morphogenetic protein 7, Osteopontin, Netrin-1, and Growth-regulated alpha protein as diagnostic and prognostic biomarkers in renal injuries.	09-22-2011
20110306063	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart-type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin-12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries.	12-15-2011
20120156701	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect C-X-C motif chemokines-1, -2, and -3 as diagnostic and prognostic biomarker assays in renal injuries.	06-21-2012

Paul H. Mcpherson, Encinitas, CA US

Patent application number	Description	Published
20080254485	Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods and compositions selected to monitor cardiorenal syndrome using assays that detect NGAL, preferably together with assays that detect natriuretic peptides such as BNP. Such methods and compositions can provide early indications of a deterioration in cardiorenal syndrome status, including prognosis regarding mortality and worsening renal function.	10-16-2008
20090004755	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND/OR PROGNOSIS IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROMES - The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant.	01-01-2009
20100086944	Methods and Compositions for Diagnosis and Prognosis of Renal Artery Stenosis - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects in the context of renal artery stenosis (RAS). In particular, the invention relates to using assays that detect NGAL, their use to diagnose RAS in subjects suffering from hypertension, and their use in prognosis, particularly of mortality and worsening renal function.	04-08-2010
20100167307	NOVEL METHODS FOR THE ASSAY OF TROPONIN I AND T AND COMPLEXES OF TROPONIN I AND T AND SELECTION OF ANTIBODIES FOR USE IN IMMUNOASSAYS - Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin I an T and the binary and ternary complexes, as well as which form of troponin present in the blood, may be related to the metabolic state of the heart. Disclosed is a system to determine the presence of a troponin form or a group of troponin forms in a sample of whole blood, serum or plasma.	07-01-2010
20100240078	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND/OR PROGNOSIS IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROMES - The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant.	09-23-2010
20110014629	METHODS FOR IMPROVING THE RECOVERY OF TROPONIN I AND T IN MEMBRANES, FILTERS AND VESSELS - A method to facilitate recovery troponin I and/or troponin T from a sample comprising addition of troponin C to the sample or to a surface from which the troponin I and/or troponin T are recovered.	01-20-2011
20110104726	Methods and Compositions for Monitoring and Risk Prediction in Cardiorenal Syndrome - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods and compositions selected to monitor cardiorenal syndrome using assays that detect NGAL, preferably together with assays that detect natriuretic peptides such as BNP. Such methods and compositions can provide early indications of a deterioration in cardiorenal syndrome status, including prognosis regarding mortality and worsening renal function.	05-05-2011
20110143455	NOVEL METHODS FOR THE ASSAY OF TROPONIN I AND T AND COMPLEXES OF TROPONIN I AND T AND SELECTION OF ANTIBODIES FOR USE IN IMMUNOASSAYS - Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin I an T and the binary and ternary complexes, as well as which form of troponin present in the blood, may be related to the metabolic state of the heart. Disclosed is a system to determine the presence of a troponin form or a group of troponin forms in a sample of whole blood, serum or plasma.	06-16-2011
20110281280	Methods and Compositions for Monitoring and Risk Prediction in Cardiorenal Syndrome - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods and compositions selected to monitor cardiorenal syndrome using assays that detect NGAL, preferably together with assays that detect natriuretic peptides such as BNP. Such methods and compositions can provide early indications of a deterioration in cardiorenal syndrome status, including prognosis regarding mortality and worsening renal function.	11-17-2011
20120129198	NOVEL METHODS FOR THE ASSAY OF TROPONIN I AND T AND COMPLEXES OF TROPONIN I AND T AND SELECTION OF ANTIBODIES FOR USE IN IMMUNOASSAYS - Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin I an T and the binary and ternary complexes, as well as which form of troponin present in the blood, may be related to the metabolic state of the heart. Disclosed is a system to determine the presence of a troponin form or a group of troponin forms in a sample of whole blood, serum or plasma.	05-24-2012

Steve Mcpherson, Menlo Park, CA US

Patent application number	Description	Published
20100089319	RF RETURN PATH FOR LARGE PLASMA PROCESSING CHAMBER - A method and apparatus having a RF return path with low impedance coupling a substrate support to a chamber wall in a plasma processing system is provided. In one embodiment, a processing chamber includes a chamber body having a chamber sidewall, a bottom and a lid assembly supported by the chamber sidewall defining a processing region, a substrate support disposed in the processing region of the chamber body, a shadow frame disposed on an edge of the substrate support assembly, and a RF return path having a first end coupled to the shadow frame and a second end coupled to the chamber sidewall.	04-15-2010

Steven Mcpherson, Encinitas, CA US

Patent application number	Description	Published
20100092015	STEREO SYSTEM AND SPEAKERS FOR A WATERCRAFT - A speaker and stereo system for a watercraft are disclosed. The stereo system includes an amplifier sized and adapted to fit within an internal compartment of the watercraft, and having a power input that connects to a battery of the watercraft for power. The amplifier further includes a control input, a signal amplifier, at least two audio outputs connected to the signal amplifier, and an audio input for receiving a digital audio signal from a digital music player to be amplified by the signal amplifier. The speaker for use with the stereo system includes a speaker housing having a flattened bottom, an opening at a front face, and an enclosure that tapers and extends to a substantially pointed terminal end. The speaker further includes a waterproof loudspeaker pivotally connected within the opening of the front face of the speaker housing to face a direction substantially opposite the pointed terminal end, and a mounting mechanism for removably mounting the speaker housing to an outer surface of the watercraft.	04-15-2010