Mckenzie, AU
Brent Mckenzie, Parkville AU
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20130164291 | METHOD OF TREATING INFLAMMATORY BOWEL DISEASE - A method for treating or preventing an inflammatory bowel disease (IBD) in a subject, the method comprising administering to the subject a compound that inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) signaling. | 06-27-2013 |
Brent Mckenzie, Sunshine AU
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20100183544 | METHOD OF TREATMENT - The present invention relates generally to the field of cancer therapy. More particularly, the present invention provides a method for the treatment of gastrointestinal-type cancers and therapeutic agents useful for same. | 07-22-2010 |
20130302277 | METHOD OF TREATMENT - The present invention relates generally to the field of cancer therapy. More particularly, the present invention provides a method for the treatment of gastrointestinal-type cancers and therapeutic agents useful for same. | 11-14-2013 |
Brent S. Mckenzie, Victoria AU
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20100135998 | COMBINATION THERAPY FOR TREATMENT OF IMMUNE DISORDERS - Methods and compositions are provided for the treatment of immune disorders, such as autoimmune diseases, or cancers, involving combination therapy with agents that inhibit the development or maintenance of Th17 cells. Treatment regimens are provided in which an antagonist of a pro-inflammatory cytokine is administered for a time sufficient to alleviate signs and symptoms of an acute phase flare-up of the autoimmune disease, or cancer, and treatment with an antagonist of IL-23 is continued for a longer time to prevent recurrence of the acute event. Antagonists of PGE2 and CD161 are also disclosed for use in treatment of autoimmune, inflammatory and proliferative disorders. | 06-03-2010 |
20120156699 | Pathogenic TH17 Cells; related reagents and methods - Methods and compositions are provided for the treatment of immune disorders, such as autoimmune diseases, or cancers, involving combination therapy with agents that inhibit the development or maintenance of Th17 cells. Treatment regimens are provided in which an antagonist of a pro-inflammatory cytokine is administered for a time sufficient to alleviate signs and symptoms of an acute phase flare-up of the autoimmune disease, or cancer, and treatment with an antagonist of IL-23 is continued for a longer time to prevent recurrence of the acute event. Antagonists of PGE2 and CD161 are also disclosed for use in treatment of autoimmune, inflammatory and proliferative disorders. | 06-21-2012 |
20130287775 | COMBINATION THERAPY FOR TREATMENT OF IMMUNE DISORDERS - Methods and compositions are provided for the treatment of immune disorders, such as autoimmune diseases, or cancers, involving combination therapy with agents that inhibit the development or maintenance of Th17 cells. Treatment regimens are provided in which an antagonist of a pro-inflammatory cytokine is administered for a time sufficient to alleviate signs and symptoms of an acute phase flare-up of the autoimmune disease, or cancer, and treatment with an antagonist of IL-23 is continued for a longer time to prevent recurrence of the acute event. Antagonists of PGE2 and CD161 are also disclosed for use in treatment of autoimmune, inflammatory and proliferative disorders. | 10-31-2013 |
Brent Steven Mckenzie, Upwey AU
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20110165181 | RELAY VACCINE - The present invention provides a method and composition for raising an immune response in an animal. The method comprising administering to the animal a composition comprising a carrier and an antigen bound to a targeting moiety. The targeting moiety binds to at least one receptor that is upregulated on lymphocytes that home to MAdCAM | 07-07-2011 |
Brent Steven Mckenzie, Hoppers Crossing AU
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20110091456 | TREATMENT OF NEUROLOGICAL CONDITIONS - The present invention is directed to a method for treating an inflammatory neurodegenerative condition of the CNS in a subject comprising administering to said subject a G-CSF or G-CSFR inhibiting agent selected from the group consisting of an antibody specific for G-CSF or G-CSFR, a soluble G-CSFR or a G-CSF-binding portion thereof and a 20 to 30 nucleotide sense or antisense molecule targeted to a nucleic acid molecule encoding G-CSF. | 04-21-2011 |
20140234303 | TREATMENT OF NEUROLOGICAL CONDITIONS - The present invention is directed to a method for treating an inflammatory neurodegenerative condition of the CNS in a subject comprising administering to said subject a G-CSF or G-CSFR inhibiting agent selected from the group consisting of an antibody specific for G-CSF, a soluble G-CSFR or a G-CSF-binding portion thereof and a 20 to 30 nucleotide sense or antisense molecule targeted to a nucleic acid molecule encoding G-CSF. | 08-21-2014 |
Bruce Mckenzie, Vincentia AU
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20110126128 | FUTURE INSIGHT MAPS AND ASSOCIATED TOOLS - A diverse group of participants using on one or more client machines is enabled to generate on a user interface their solicited responses about any set of two or more independent variables that underlie a complex issue. The two or more independent variables are applied against each other. A likely outcome is predicted, wherein an application resident on a server is configured to integrate the solicited responses from the participants. The results are displayed on the display of the client machines to enable the participants to view. The participants are to develop insights related to the complex issue based on reviewing the results. | 05-26-2011 |
20150020002 | ADAPTIVELY NAVIGATING COMPLEXITY TOGETHER THROUGH COLLABORATIVE INSIGHTS - Methods and Apparatuses for a collaborative effort from a group of participants on an issue-exploration process on one or more client machines are discussed. A form-based Internet application that consists of a systematic structure of a series of tab forms to set up a framework for a collaborative effort from a group of participants on an issue-exploration process is configured for an initial issue. The form-based Internet application via the series of tab forms is configured to enable and collect knowledge and insights from the group of participants during the stages of the issue-exploration process. The form-based Internet application has an open framework with the stages of the issue-exploration process in that an actual content of the ideas contributed by participants actively shapes a non-linear progression of the issue-exploration process from the initial issue to the current issue in the issue-exploration process. | 01-15-2015 |
Cameron K. Mckenzie, Toowong AU
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20160104295 | METHODS AND SYSTEM FOR BLASTING VIDEO ANALYSIS - Blasting video analysis techniques and systems are presented using vibration compensated background analysis with automated determination of blast origin coordinates and highest point coordinates using blast outline coordinates for post-origin frames. Blast expansion trajectories of the highest particle are estimated in frames preceding the highest point frame, and estimated blast parameters including maximum height and initial blast velocity are computed independent of blast data. | 04-14-2016 |
David Mckenzie, Artarmon AU
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20140324156 | IMPLANTABLE DEVICE WITH PLASMA POLYMER SURFACE - A deformable implantable medical device such as a stent comprising metallic, polymer and/or composite substrate having a columnar structured plasma polymer surface capable of binding functional biological molecules. The polymer surface can be bound to the substrate through a mixed or graded interface formed by a co-deposition process where a substrate material is deposited with carbon containing species while gradually reducing the substrate material proportion and increasing the carbon containing species proportion. The device is able to undergo deformation without substantial delamination of the plasma polymer surface. | 10-30-2014 |
20160022869 | BIOLOGICAL FUNCTIONALISATION OF SUBSTRATES - The invention relates to an activated metallic, semiconductor, polymer, composite and/or ceramic substrate, the substrate being bound through a mixed or graded interface to a hydrophilic polymer surface that is activated to enable direct covalent binding to a functional biological molecule, the polymer surface comprising a sub-surface that includes a plurality of cross-linked regions, as well as to such activated substrates that have been functionalised with a biological molecule and to devices comprising such functionalised substrates. Such substrates can be produced by a method comprising steps of: a. exposing a surface of the substrate to any or more of (i) to (iii): (i) plasma ion implantation with carbon containing species; (ii) co-deposition under conditions in which substrate material is deposited with carbon containing species while gradually reducing substrate material proportion and increasing carbon containing species proportion; (iii) deposition of a plasma polymer surface layer with energetic ion bombardment; incubating the surface treated according to step (a) with a desired biological molecule. | 01-28-2016 |
David Mckenzie, New South Wales AU
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20090305381 | Activated Polymers Binding Biological Molecules - The present invention relates to activated polymer substrates capable of binding functional biological molecules, to polymer substrates comprising bound and functional biological molecules, to devices comprising such substrates and to methods of producing them. | 12-10-2009 |
20100227372 | BIOLOGICAL FUNCTIONALISATION OF SUBSTRATES - The invention relates to an activated metallic, semiconductor, polymer, composite and/or ceramic substrate, the substrate being bound through a mixed or graded interface to a hydrophilic polymer surface that is activated to enable direct covalent binding to a functional biological molecule, the polymer surface comprising a sub-surface that includes a plurality of cross-linked regions, as well as to such activated substrates that have been functionalised with a biological molecule and to devices comprising such functionalised substrates. Such substrates can be produced by a method comprising steps of: a. exposing a surface of the substrate to any or more of (i) to (iii): (i) plasma ion implantation with carbon containing species; (ii) co-deposition under conditions in which substrate material is deposited with carbon containing species while gradually reducing substrate material proportion and increasing carbon containing species proportion; (iii) deposition of a plasma polymer surface layer with energetic ion bombardment; incubating the surface treated according to step (a) with a desired biological molecule. | 09-09-2010 |
David Robert Mckenzie, Artarmon AU
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20090014665 | Fibre Optic Dosimeter - A dosimeter ( | 01-15-2009 |
20100096540 | Fibre Optic Dosimeter - A dosimeter for radiation fields is described. The dosimeter includes a scintillator a light pipe having a first end in optical communication with the scintillator and a light detector. The light pipe may have a hollow core with a light reflective material about the periphery of the hollow core. The dosimeter may further include a light source that generates light for use as a calibrating signal for a measurement signal and/or for use to check the light pipe. | 04-22-2010 |
20110270356 | POLYMERIC ENCAPSULATION OF MEDICAL DEVICE COMPONENTS - A hermetic encapsulation and to a method of producing the same is provided. The hermetic encapsulation comprises a polymeric material disposed about a device component and has one or more plasma activated surfaces directly bonded to one another to hermetically seal the component within the material. | 11-03-2011 |
20120037808 | Fibre Optic Dosimeter - A dosimeter for radiation fields is described. The dosimeter includes a scintillator a light pipe having a first end in optical communication with the scintillator and a light detector. The light pipe may have a hollow core with a light reflective material about the periphery of the hollow core. The dosimeter may further include a light source that generates light for use as a calibrating signal for a measurement signal and/or for use to check the light pipe. | 02-16-2012 |
Gladys Mckenzie, Dundas AU
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20150119911 | TONGUE SCRAPER - The tongue cleaner includes an elongated generally straight scraping member terminated at each end by grip structures. The scraping member is constructed of a flexible and resilient material allowing the scraping member to be bendable from its generally straight configuration into at least a curved shape, ‘C’ shape, ‘V’ shape or ‘U’ shape configuration. The scraping member resiliently returns to its straight configuration in the absence of any bending forces. The flexible and resilient material is preferably a plastic, silicone, rubber, metal, wood or a combination of such materials. The preferred material is silicone rubber. | 04-30-2015 |
Gregory Dominic Mckenzie, Kingsgrove AU
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20100325584 | Method and System for Facilitating the Review of Electronic Documents - A method and system is provided for facilitating the review of electronic documents such as patent, trademark and design documents. Example embodiments of methods provide a business context for performing the review, a role within the business context together with the event that is the reason for the review to be requested. | 12-23-2010 |
Ian Mckenzie, South Yarra AU
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20140214509 | SYSTEM AND METHOD OF EFFECTING A MERCHANT FUNDED REWARD - A computer implemented method of effecting a merchant funded reward when a consumer purchases goods and/or services from a merchant using an electronic payment, including a processor executing instruction code causing collection of transaction details of the consumer purchase, processing of the transaction details to calculate any associated reward, and notification of the entire reward to be collected from the merchant. | 07-31-2014 |
Ian Farquhar Campbell Mckenzie, Point Lonsdale AU
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20090123470 | Antibodies Against Cancer - An isolated binding partner of a Cripto-1 protein, Pim-1 protein or an antigen present in a colon cancer cell lysate is described. The binding partner inhibits growth of one or more cancer cell types and may be used in an anti-cancer agent for treating cancer in a subject. The binding partner may also be used in a method of inducing apoptosis in a cancer cell, as well as in a method of sensitizing a cancer cell to a cytotoxic compound. In addition, a cancer vaccine is described wherein the vaccine comprises a Cripto-1 protein (or an antigenic fragment thereof), Pim-1 protein (or an antigenic fragment thereof) or an antigen present in a colon cancer cell lysate or, alternatively, comprises an expressible DNA molecule encoding a Cripto-1 protein (or an antigenic fragment thereof), Pim-1 protein (or an antigenic fragment thereof) or an antigen present in a colon cancer cell lysate. | 05-14-2009 |
20100119514 | Antibodies Against Cancer - An isolated binding partner of a Cripto-1 protein, Pim-1 protein or an antigen present in a colon cancer cell lysate is described. The binding partner inhibits growth of one or more cancer cell types and may be used in an anti-cancer agent for treating cancer in a subject. The binding partner may also be used in a method of inducing apoptosis in a cancer cell, as well as in a method of sensitising a cancer cell to a cytotoxic compound. In addition, a cancer vaccine is described wherein the vaccine comprises a Cripto-1 protein (or an antigenic fragment thereof), Pim-1 protein (or an antigenic fragment thereof) or an antigen present in a colon cancer cell lysate or, alternatively, comprises an expressible DNA molecule encoding a Cripto-1 protein (or an antigenic fragment thereof), Pim-1 protein (or an antigenic fragment thereof) or an antigen present in a colon cancer cell lysate. | 05-13-2010 |
Ian Farquhar Campbell Mckenzie, Victoria AU
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20090317414 | CANCER VACCINE COMPRISING A MUCIN 1 (MUC1) T CELL EPITOPE-DERIVED PEPTIDE - A cancer vaccine, and a composition for the ex vivo priming of dendritic cells, is disclosed which comprises a MUC1 T cell epitope-derived peptide or peptide analogue capable of provoking a cytotoxic T cell immune response. Particular MUC1 T cell epitope-derived peptides disclosed include TTAPPVHGL, STAPPVHGL, STAPPAHGL, TTAPPAHGV and SAPDTYPAL. | 12-24-2009 |
Ian Farquhar Campbell Mckenzie, Brunswick AU
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20110033493 | VACCINE - The present invention provides a method of immunising a subject comprising the step of administering a composition comprising an antigen and a carbohydrate polymer comprising mannose to a mucosal site of the subject, methods of use of the composition for vaccination and sterilization and use of the composition in manufacturing a medicament. | 02-10-2011 |
Justin Dean Mckenzie, East Burwood AU
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20090217918 | METHOD AND APPARATUS FOR PROJECTING AN ARTICLE - The present invention relates generally to methods and devices for projecting articles. In particular, the present invention relates to a method and apparatus for projecting balls and like articles for interaction with a player where a player may, for example, be considered a human training for or playing a ball sport or, an animal such as a dog exercising by retrieving the projected article. In one form, the invention relates to a method and apparatus for projecting an article comprising: feeding at least one article into a launching means wherein the launching means comprises a plurality of independently controlled rotating drive devices each device adapted to provide contact between the launching means and the at least one article for providing a component of drive force to launch the at least one article; attenuating at least one component of drive force to control the 3-Dimensional spin of the launched article by moving at least one drive device whilst maintaining the orientation of the axis of rotation of said drive device. | 09-03-2009 |
Mark Mckenzie, Sunbury AU
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20110256152 | Methods Of Treating And Preventing Glucose Toxicity - The present invention relates to a method for treating and/or preventing a disease associated with glucose toxicity in a subject which may comprise administering to the subject a compound that reduces the level of Bim, PUMA and/or Bax activity in a cell of the subject. Furthermore, provided is a method for culturing cells susceptible to exposure to high concentrations of glucose, which may comprise delivering to the cells, or progenitor cells thereof, a compound that reduces the level of Bim, PUMA and/or Bax activity in the cells. | 10-20-2011 |
20140072567 | Methods Of Treating And Preventing Glucose Toxicity - The present invention relates to a method for treating and/or preventing a disease associated with glucose toxicity in a subject which may comprise administering to the subject a compound that reduces the level of Bim, PUMA and/or Bax activity in a cell of the subject. Furthermore, provided is a method for culturing cells susceptible to exposure to high concentrations of glucose, which may comprise delivering to the cells, or progenitor cells thereof, a compound that reduces the level of Bim, PUMA and/or Bax activity in the cells. | 03-13-2014 |
Robert G. Mckenzie, Nth Balwyn AU
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20130111659 | Better Electric Person Transfer, Load and Unload Device - A person load and unload transfer device including: an adjustable wheeled base frame; | 05-09-2013 |
Stuart C. Mckenzie, Brisbane AU
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20160055140 | PEER TO PEER SPREADSHEET PROCESSING - A distributed system and process for sharing a spreadsheet model. A spreadsheet to be shared is configured by defining input fields, processing parameters for the input fields, and output fields, and a template including the input and output fields is created. The template is shared with a remote user, who enters data into the input fields of the template. The input data is transferred for processing, after which results are provided to the remote user in the defined output fields of the template. | 02-25-2016 |
Warren Mckenzie, Wilberforce AU
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20110189446 | Process and System for Fabrication of Patterns on a Surface - The invention provides a system and process of patterning structures on a carbon based surface comprising exposing part of the surface to an ion flux, such that material properties of the exposed surface are modified to provide a hard mask effect on the surface. A further step of etching unexposed parts of the surface forms the structures on the surface. The inventors have discovered that by controlling the ion exposure, alteration of the surface structure at the top surface provides a mask pattern, without substantially removing any material from the exposed surface. The mask allows for subsequent ion etching of unexposed areas of the surface leaving the exposed areas raised relative to the unexposed areas thus manufacturing patterns onto the surface. For example, a Ga+ focussed ion beam exposes a pattern onto a diamond surface which produces such a pattern after its exposure to a plasma etch. The invention is particularly suitable for patterning of clear well-defined structures down to nano-scale dimensions. | 08-04-2011 |