Mcdonald, MA
Alice Mcdonald, Swampscott, MA US
Patent application number | Description | Published |
---|---|---|
20160130344 | ANTI-GCC ANTIBODY MOLECULES AND METHODS FOR USE OF SAME - Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein. | 05-12-2016 |
Alice A. Mcdonald, Swampscott, MA US
Patent application number | Description | Published |
---|---|---|
20130287783 | ANTI-GCC ANTIBODY MOLECULES AND METHODS FOR USE OF SAME - Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein. | 10-31-2013 |
Benjamin Edward Mcdonald, Holliston, MA US
Patent application number | Description | Published |
---|---|---|
20100229654 | METHOD AND SYSTEM FOR MULTI-PATH ULTRASONIC FLOW RATE MEASUREMENT - In one embodiment, a multi-path ultrasonic flow meter for determining the flow rate of a fluid in a conduit is disclosed comprising at least two transducer pairs attached to the conduit at two chord locations, one greater than and one less than a mid-radius chord, wherein the composite ratio the two path velocities to the flow rate is substantially constant over the range of Reynolds numbers. In another embodiment, a method of determining the flow rate of a fluid in a conduit is disclosed comprising the steps of determining a composite velocity by determining a weighted average of a plurality of path velocities, determining a chord velocity ratio based on the path velocities, determining a profile correction factor based on the composite velocity and the chord velocity ratio, and determining the flow rate based on the composite velocity and the profile correction factor. | 09-16-2010 |
20130098167 | FLOW CELL FOR A FLOW METER - A flow cell that includes a sensor body with internal cable channels for routing cables from the sensor ports to communicate with a flow meter is disclosed. | 04-25-2013 |
20130219707 | SENSOR PORT INSERT APPARATUS - An insert apparatus for installing a transducer assembly in a sensor port of a flow cell is disclosed. The transducer assembly is installed in the cavity of the insert body without the use of glues or adhesives to bond the transducer assembly to the cavity. | 08-29-2013 |
20140083181 | REMOVABLE SENSOR PORT INSERT APPARATUS - An apparatus configured for insertion into a sensor port of a flow cell is disclosed. The apparatus includes an insert body, a sensor located in the cavity of the insert body, and an insert body holding nut and a sensor holding nut threaded to the interior surface of the sensor port. | 03-27-2014 |
20140103274 | APPARATUS AND METHOD FOR INSTALLING OR REMOVING A CABLE - An apparatus and method for installing or removing a cable is disclosed. A cable tool includes a cable channel with two channels having different channel openings for receiving or releasing the cable. The first end of the cable channel has a smaller channel opening and an arm that can be used to remove the cable and disconnect a connector on the end of the cable from a sensor. | 04-17-2014 |
20140198822 | APPARATUS AND METHOD FOR DETERMINING TEMPERATURE - An apparatus and method for determining temperature is disclosed. An ultrasonic signal is generated that propagates through a buffer and a portion of the signal is reflected at an interface. A time of flight is measured between generating the ultrasonic signal and detecting the reflected portion. The temperature is determined based on the time of flight of the reflected signal. | 07-17-2014 |
20150101463 | APPARATUS FOR HOLDING AND APPLYING TORQUE TO A NUT - A tool for holding and applying torque to a nut including a keyway. The tool includes a longitudinal body having a longitudinal axis and a body channel. A longitudinal key is disposed in the body channel with one end of the key configured to engage the keyway of the nut. A first key portion contacts the body channel while a second key portion extends over the body channel forming a gap between the key and the body channel prior to insertion of the key into the keyway of the nut. The second key portion is configured to be resiliently deflected radially inward toward the longitudinal axis of the longitudinal body when the second key portion engages the keyway of the nut. | 04-16-2015 |
20150177708 | SYSTEMS AND METHODS FOR DYNAMIC MAPPING FOR END DEVICES OF CONTROL SYSTEMS - The subject matter disclosed herein relates to end devices (e.g., meters, sensors, pumps, etc.) of an industrial monitoring system or an industrial control system. A system includes an end device having processing circuitry configured to execute instructions stored in at least one memory device to enable the end device to collect and store a plurality of measurements of operational parameters of a monitored system in the at least one memory device according to a dynamic mapping that is updatable. | 06-25-2015 |
Christopher D. Mcdonald, Newburyport, MA US
Patent application number | Description | Published |
---|---|---|
20130331825 | FLEXIBLE PROBE WITH ADJUSTABLE TIP - An instrument includes a handle portion, an actuator, a shaft, a rigid member, and an angular control mechanism. The shaft has a proximal end and a distal end with an electrode region, and a flexible region in between. Moving the actuator causes portions of the flexible region distal of a pivot region to bend such that an angular orientation and a radial offset of the electrode region reach a maximum angular orientation and a maximum radial offset, respectively, when the actuator reaches the end position. A distal portion of the rigid member defines the pivot region. Moving the rigid member along the shaft causes the pivot region to translate. The maximum radial offset varies depending on the position of the pivot region. The angular control mechanism is configured to control the angular orientation such that the maximum angular orientation is same regardless of the position of the rigid member. | 12-12-2013 |
20150202001 | FLEXIBLE PROBE WITH ADJUSTABLE TIP - An instrument includes a handle portion, an actuator, a shaft, a rigid member, and an angular control mechanism. The shaft has a proximal end and a distal end with an electrode region, and a flexible region in between. Moving the actuator causes portions of the flexible region distal of a pivot region to bend such that an angular orientation and a radial offset of the electrode region reach a maximum angular orientation and a maximum radial offset, respectively, when the actuator reaches the end position. A distal portion of the rigid member defines the pivot region. Moving the rigid member along the shaft causes the pivot region to translate. The maximum radial offset varies depending on the position of the pivot region. The angular control mechanism is configured to control the angular | 07-23-2015 |
David Mcdonald, Medway, MA US
Patent application number | Description | Published |
---|---|---|
20120029299 | Physiological status monitoring system - A physiological monitoring system includes a sensor subsystem worn by a person including at least a one sensor. A dock is associated with the sensor subsystem and includes a first connector component electrically connected to the sensor. A portable transmitting unit is received in the dock and includes a transmitter and a connector component removeably mateable with the dock connector component to route sensor data to the transmitter. | 02-02-2012 |
20120035426 | Extended range physiological monitoring system - A physiological monitoring system includes a sensor subsystem worn by a person including at least one physiological sensor. A dock associated with the sensor subsystem includes a first connector component electrically connected to the physiological sensor. A portable transmitting unit is received by the dock and includes a transmitter and a connector component removeably mateable with the dock connector component to route physiological data to the transmitter. A base station receives and displays physiological data. A portable relay unit includes a receiver for receiving physiological data from the portable transmitting unit, a transmitter for relaying physiological data to the base station, an antenna subsystem for the receiver and transmitter, and a portable power source for the receiver and transmitter. | 02-09-2012 |
20120078127 | Physiological status monitoring system - A load score system includes a metabolic sensor such as a heart rate sensor for a subject is configured to output metabolic data for the subject. A biomechanical load sensing subsystem for the subject is configured to output biomechanical load data. A speed sensor subsystem for the subject is configured to output speed data. One or more databases store zones and a weighting factor for each zone for metabolic data, biomechanical load data, and speed data. A performance module is responsive to the metabolic data, the biomechanical load data, and the speed data and the one or more databases and is configured to calculate a metabolic load score for the subject. A biomechanical load score for the subject and a speed load score for the subject are also calculated. An output module displays the subject's calculated metabolic, biomechanical, and speed load scores. | 03-29-2012 |
Earl Mcdonald, Cambridge, MA US
Patent application number | Description | Published |
---|---|---|
20150238515 | ORGANIC COMPOSITIONS TO TREAT KRAS-RELATED DISEASES - The present disclosure relates to RNAi agents useful in methods of treating KRAS-related diseases such as a proliferative disease, including without limitation a solid or liquid cancer, adenocarcinoma, colorectal cancer, advanced and/or metastatic colorectal cancer, colon cancer, lung, non-small cell lung cancer and lung adenocarcinoma, acute myelogenous lung, bladder, brain, breast, cervical, endometrial, gastric, head and neck, kidney, leukemia, myelodysplastic syndrome, myeloid leukemia, liver, melanoma, ovarian, pancreatic, prostate, testicular, thyroid cancers, and cardio-facio-cutaneous (CFC) syndrome and Noonan syndrome, and similar and related diseases, using a therapeutically effective amount of a RNAi agent to KRAS. | 08-27-2015 |
Frank T. Mcdonald, Bedford, MA US
Patent application number | Description | Published |
---|---|---|
20100114116 | Medical Device Control System - A control system for allowing a physician to control the orientation of a medical device or a medical instrument in a variety of directions with one hand. An actuator selectively tensions one or more control cables having ends secured at or adjacent a distal tip of the medical device in order to bend the distal tip in a desired direction. In one embodiment, a physician can adjust the movement of the distal tip in a desired direction without affecting the orientation of the medical device in other directions. | 05-06-2010 |
Glenn Mcdonald, Cambridge, MA US
Patent application number | Description | Published |
---|---|---|
20100145902 | METHODS AND SYSTEMS TO TRAIN MODELS TO EXTRACT AND INTEGRATE INFORMATION FROM DATA SOURCES - Methods and systems to model and acquire data from a variety of data and information sources, to integrate the data into a structured database, and to manage the continuing reintegration of updated data from those sources over time. For any given domain, a variety of individual information and data sources that contain information relevant to the schema can be identified. Data elements associated with a schema may be identified in a training source, such as by user tagging. A formal grammar may be induced appropriate to the schema and layout of the training source. A Hidden Markov Model (HMM) corresponding to the grammar may learn where in the sources the elements can be found. The system can automatically mutate its schema into a grammar matching the structure of the source documents. By following an inverse transformation sequence, data that is parsed by the mutated grammar can be fit back into the original grammar structure, matching the original data schema defined through domain modeling. Features disclosed herein may be implemented with respect to web-scraping and data acquisition, and to represent data in support of data-editing and data-merging tasks. A schema may be defined with respect to a graph-based domain model. | 06-10-2010 |
Glenn Mcdonald, Marston Mills, MA US
Patent application number | Description | Published |
---|---|---|
20150354902 | THERMAL TRANSFER SYSTEM - A thermal transfer system for a pressure vessel adapted for use in an underwater environment includes a housing having a bore adapted to receive a heat pipe. Embodiments of the housing include a mounting flange for mounting the housing to the pressure vessel, a radially extending profile to enhance thermal transfer between the housing and the underwater environment, and an aperture in fluidic communication with the bore. A method of providing thermal transfer between an interior of the pressure vessel and the underwater environment includes inserting the heat pipe into the bore, sealing a distal end of the bore, and mounting the housing to the pressure vessel. | 12-10-2015 |
Glenn E. Mcdonald, Marston Mills, MA US
Patent application number | Description | Published |
---|---|---|
20080289241 | Artificial Fishing Lure that Generates Visual and Audible Signals - A fishing lure that contains electronics and provides the lure with characteristics that better attract fish. The fishing lure has a body with external flank surfaces. A plurality of light sources are contained within the lure. The light sources shine light out from the flank surfaces of the lure when activated. A light sensor in the lure detects ambient light levels outside of the lure. The light levels detected by the light sensor are used to control the output intensity of the light sources as they activate. In addition to internal light sources, the fishing lure may also contain a transducer for creating acoustical particle motion in the water. Both the light sources and the transducer are controlled in a unique manner that causes the lure to closely mimic the visual and acoustical properties of a live baitfish. | 11-27-2008 |
Glenn Elwin Mcdonald, Marston Mills, MA US
Patent application number | Description | Published |
---|---|---|
20150131084 | Sensor System for Environmental Impact Monitoring - A self-contained monitor array for measuring at least one type of electromagnetic emission and at least one type of mechanical wave emission from a marine-based and/or terrestrial human activity or installation such as alternate energy sources. A multi-modal monitor system includes at least two such arrays, at least one clock, and at least one data storage unit. | 05-14-2015 |
James E. Mcdonald, Monson, MA US
Patent application number | Description | Published |
---|---|---|
20090253967 | PORTABLE IMAGING SYSTEM EMPLOYING A MINIATURE ENDOSCOPE - A cart or man-portable system and method for performing endoscopic procedures is provided. A portable display device, such as a laptop computer, is coupled to a handle comprising a miniature camera and fiber optic illumination subsystem. A sterile disposable portion is fitted over the illumination subsystem and inserted into a target area on a patient. Images of the target area are conveyed from the camera to the display device while an endoscopic procedure is performed, thus facilitating real-time diagnosis during the procedure. | 10-08-2009 |
20110299065 | SYSTEM AND METHOD FOR MEASURING RADIANT ENERGY IN GAS TURBINE ENGINES, COMPONENTS AND RIGS - One embodiment of the present invention is a unique system for measuring radiant energy in gas turbine engines, gas turbine engine components and gas turbine engine/component rigs. Another embodiment is a unique method for measuring radiant energy in gas turbine engines, gas turbine engine components and gas turbine engine/component rigs. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for measuring radiant energy. Further embodiments, forms, features, aspects, benefits, and advantages of the present application shall become apparent from the description and figures provided herewith. | 12-08-2011 |
James E. Mcdonald, Dudley, MA US
Patent application number | Description | Published |
---|---|---|
20120071721 | DISPOSABLE SHEATH FOR A MINIATURE ENDOSCOPE - An endoscopic has an fiber optic waveguide that transmits an image from a distal end to a proximal end, the waveguide having an outer diameter of less than 3 mm. A lens system is positioned at the distal end of the fiber optic waveguide. An imaging device is optically coupled to the proximal end of fiber optic waveguide. A disposable sheath extends about the fiber optic waveguide to provide a sterile barrier, and in a preferred embodiment the sheath includes an illumination channel. In a preferred embodiment, the lens system has a first lens element, a second lens element and an aperture stop. | 03-22-2012 |
Jeffrey D. Mcdonald, Foxborough, MA US
Patent application number | Description | Published |
---|---|---|
20100145955 | METHOD AND SYSTEM FOR VIRTUALLY PRINTING DIGITAL CONTENT TO A SEARCHABLE ELECTRONIC DATABASE FORMAT - A computer implemented method and system and computer program product are provided for virtually printing digital content to a searchable electronic database format to facilitate locating or analyzing desired content. The method includes the steps of: (a) providing digital content at a computer system; (b) dividing the digital content into one or more virtual pages; (c) extracting content data from the one or more virtual pages, and storing the content data in a database; and (d) generating associations between the content data and respective virtual pages from which the content data was extracted, and storing the associations in a database. | 06-10-2010 |
Jeffrey Douglas Mcdonald, Foxborough, MA US
Patent application number | Description | Published |
---|---|---|
20100328353 | METHOD AND SYSTEM FOR DISPLAYING AN IMAGE ON A DISPLAY OF A COMPUTING DEVICE - A computer implemented method of displaying an image on a display of a computing device, includes the steps of: (a) displaying an image on the display of the computing device; (b) receiving a user input for drawing a mark on the image indicative of a desired operation to be performed on the image; (c) displaying the mark on the image; (d) determining an operation to be performed on the image based on the mark; and (e) preparing and displaying an image as modified or generated by the operation. | 12-30-2010 |
John J. Mcdonald, Lynnfield, MA US
Patent application number | Description | Published |
---|---|---|
20090199120 | Customizable, reconfigurable graphical user interface - A graphical user interface (“GUI”) for a software-controlled media/data organizer and playback system including a display screen with a plurality of user-activatible search and selection buttons for use in accessing the media/data selections from one or more storage devices. The GUI, when started on a suitable system, automatically senses the system's display screen size and automatically configures the GUI buttons, windows and other characteristics of the display to conform thereto. The GUI also enables the user to configure and customize the GUI buttons, windows and other display characteristics to suit his/her particular needs and preferences. Additionally, the GUI includes an improved asynchronous media/data selection search facility that displays in a GUI search window, substantially immediately, the initial results of a search request while additional searching proceeds asynchronously “behind the scenes” until the follow-on results are ready for display. The search facility is also adopted to account for misspellings, date transposition and other errors and other errors made by the user during entry of search requests. Other improved features of the GUI include its ability to merge or synchronize the search and selection buttons and media/data selections among different systems and the ability to monitor and report details of a user's activity on a given system. | 08-06-2009 |
Joseph Mcdonald, Rockport, MA US
Patent application number | Description | Published |
---|---|---|
20150084757 | METHODS AND SYSTEMS FOR DETERMINING AUTO ACCIDENTS USING MOBILE PHONES AND INITIATING EMERGENCY RESPONSE - A method for providing automatic crash management (ACM) is provided. An ACM application is enabled on a mobile device. Data is collected from a plurality of sensors associated with the mobile device. The data from the plurality of sensors is processed with the ACM application. The processed data is monitored with accident logic of the ACM application running on the mobile device to determine whether a crash has been detected. The data from the plurality of sensors is automatically streamed to the off-board server for further analysis upon detection of the crash. | 03-26-2015 |
Joseph John Mcdonald, Sudbury, MA US
Patent application number | Description | Published |
---|---|---|
20140296233 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 10-02-2014 |
20150376208 | MK2 INHIBITORS AND USES THEREOF - The present invention provides compounds, compositions thereof, and methods of using the same. | 12-31-2015 |
20160046634 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention relates to compounds useful as inhibitors of protein kinases, containing a cysteine residue in the ATP binding site. The invention further provides for pharmaceutically acceptable compositions comprising therapeutically effective amounts of one or more of the protein kinase inhibitor compounds and methods of using said compositions in the treatment of cancers and carcinomas. | 02-18-2016 |
20160075720 | MK2 INHIBITORS AND USES THEREOF - The present invention provides compounds, compositions thereof, and methods of using the same. | 03-17-2016 |
Karen Mcdonald, North Billerica, MA US
Patent application number | Description | Published |
---|---|---|
20110106235 | METHOD AND APPARATUS FOR DEPLOYMENT OF AN ENDOLUMINAL DEVICE - An introducer deploys an endoluminal device in a distal location from a proximal location. The introducer comprises a retrograde portion, an anterograde portion axially moveable relative to the retrograde portion, a shaft having a distal tip and an anterograde sheath attached to the distal tip, and anchoring means in at least one of the retrograde portion or the anterograde portion for anchoring the device during deployment from its proximal end to its distal end. An inner sheath may be mounted concentrically over the shaft with the endoluminal device mounted concentrically over the inner sheath. The anchoring device may comprise an inflatable balloon mounted radially inside the retrograde portion, a tether, or an extended portion of the endoluminal device confined by a notch in the interface of two sheaths in the retrograde portion of the introducer, or may comprise a holder in the anterograde portion. | 05-05-2011 |
Keith F. Mcdonald, Lincoln, MA US
Patent application number | Description | Published |
---|---|---|
20150293234 | Positioning, Navigation, and Timing Device Interference and Spoofing Detector With Timing Mitigation - Disclosed herein are system, method, and computer program product embodiments for a GNSS interference and spoofing fast detection and mitigation system. A RF signal associated with a PNT device, such as a GNSS receiver, is received. The received RF signal is split into a plurality of sub-data signals. The received RF signal is re-routed by sending each of the plurality of sub-data signals to at least one of a processing module and a switching module. An anomaly associated with a second sub-data signal is detected. The anomaly is detected during a capture period of an adversarial attack on the PNT device, prior to corruption of any associated system depending on outputs from the PNT device. An output of a first sub-data signal of the plurality of sub-data signals is terminated based on the anomaly detected with the second sub-data signal. | 10-15-2015 |
Matthew M. Mcdonald, Quincy, MA US
Patent application number | Description | Published |
---|---|---|
20110106757 | Fixed content storage within a partitioned content platform, with replication - A content platform (or “cluster”) that comprises a redundant array of independent nodes is logically partitioned. Using a web-based interface, an administrator defines one or more “tenants” within the cluster, wherein a tenant has a set of attributes: namespaces, administrative accounts, data access accounts, and a permission mask. A namespace is a logical partition of the cluster that serves as a collection of objects typically associated with at least one defined application. Each namespace has a private file system with respect to other namespaces. This approach enables a user to segregate cluster data into logical partitions. According to this disclosure, tenant information, including all associated namespaces, in the cluster (the “source cluster”) is replicated to at least one target cluster over a replication link. Preferably, replication is available for multiple tenants in the source cluster, and a replication algorithm ensures that a particular tenant can be added to the replication link without stalling the progress of other tenants. | 05-05-2011 |
20110106770 | Fixed content storage within a partitioned content platform using namespaces, with versioning - Archive cluster management is enhanced by logically partitioning a physical cluster that comprises a redundant array of independent nodes. Using a web-based interface, an administrator defines one or more “tenants” within the archive cluster, wherein a tenant has a set of attributes: namespaces, administrative accounts, data access accounts, and a permission mask. A namespace is a logical partition of the cluster that serves as a collection of objects typically associated with at least one defined application. Each namespace has a private file system with respect to other namespaces. This approach enables a user to segregate cluster data into logical partitions. Using the administrative interface, a namespace associated with a given tenant is selectively configured without affecting a configuration of at least one other namespace in the set of namespaces. One configuration option is “versioning,” by which an administrator can elect to enable multiple versions of a same data object to be stored in association with a given namespace. Each version of the data object has associated therewith a time of storage attribute that uniquely identifies the version in the archive. Once versioning is enabled for a namespace, the administrator can set a configuration parameter identifying a time period for maintaining a version in the archive cluster, as well as a parameter for a time period for maintaining a version of the data object on a replica associated with the archive cluster. A current version of the data object is freely accessible in the archive, and a prior version may be browsed via an API. Preferably, versioning is disabled for a data object under retention. | 05-05-2011 |
20110106771 | Fixed content storage within a partitioned content platform, with disposition service - A content platform (or “cluster”) that comprises a redundant array of independent nodes is logically partitioned. Using a web-based interface, an administrator defines one or more “tenants” within the cluster, wherein a tenant has a set of attributes: namespaces, administrative accounts, data access accounts, and a permission mask. A namespace is a logical partition of the cluster that serves as a collection of objects typically associated with at least one defined application. Each namespace has a private file system with respect to other namespaces. This approach enables a user to segregate cluster data into logical partitions. Using the administrative interface, a namespace associated with a given tenant is selectively configured without affecting a configuration of at least one other namespace in the set of namespaces. One configuration option is a “disposition service” that, once enabled for a namespace, automatically deletes objects that were once under retention and whose retention time has expired. Preferably, the disposition service deletes objects that do not have a “retention hold” associated therewith. The service enables the content platform to automatically reclaim cluster capacity while minimizing external involvement and archive load. | 05-05-2011 |
20140108346 | Fixed content storage within a partitioned content platform, with replication - A content platform cluster that comprises an array of nodes is logically partitioned. Using a web-based interface, an administrator defines “tenants” within the cluster, wherein a tenant has a set of attributes: namespaces, administrative accounts, data access accounts, and a permission mask. A namespace is a logical partition of the cluster that serves as a collection of objects typically associated with at least one defined application. Each namespace has a private file system with respect to other namespaces. This approach enables a user to segregate cluster data into logical partitions. Tenant information, including all associated namespaces, in the cluster (the “source cluster”) is replicated to at least one target cluster over a replication link. Preferably, replication is available for multiple tenants in the source cluster, and a replication algorithm ensures that a particular tenant can be added to the replication link without stalling the progress of other tenants. | 04-17-2014 |
Matthew Michael Mcdonald, Quincy, MA US
Patent application number | Description | Published |
---|---|---|
20120079424 | SYSTEM AND METHOD FOR OPTIMIZING PROTECTION LEVELS WHEN REPLICATING DATA IN AN OBJECT STORAGE SYSTEM - A redundant array of independent nodes are networked together. Each node executes an instance of an application that provides object-based storage. The nodes are grouped into a plurality of systems each having multiple nodes. A data protection level method comprises setting a numerical value of a system dynamic data protection level for each system of nodes; and in response to user input, setting a value of a data protection level for one or more data objects in a system, the value being a fixed numerical value or a dynamic value. If the one or more data objects have a dynamic value of the data protection level in a system, the one or more data objects inherit the system dynamic data protection level of the system in which the one or more data objects reside. The value of the data protection level represents a number of copies of data of the one or more data objects to be kept where the one or more data objects reside. | 03-29-2012 |
20140181446 | SYSTEM AND METHOD FOR OPTIMIZING PROTECTION LEVELS WHEN REPLICATING DATA IN AN OBJECT STORAGE SYSTEM - A redundant array of independent nodes are networked together. Each node executes an instance of an application that provides object-based storage. The nodes are grouped into a plurality of systems each having multiple nodes. A data protection level method comprises setting a numerical value of a system dynamic data protection level for each system of nodes; and in response to user input, setting a value of a data protection level for one or more data objects in a system, the value being a fixed numerical value or a dynamic value. If the one or more data objects have a dynamic value of the data protection level in a system, the one or more data objects inherit the system dynamic data protection level of the system in which the one or more data objects reside. The value of the data protection level represents a number of copies of data of the one or more data objects to be kept where the one or more data objects reside. | 06-26-2014 |
20160004760 | SYSTEM AND METHOD FOR OPTIMIZING PROTECTION LEVELS WHEN REPLICATING DATA IN AN OBJECT STORAGE SYSTEM - A redundant array of independent nodes are networked together. Each node executes an instance of an application that provides object-based storage. The nodes are grouped into a plurality of systems each having multiple nodes. A data protection level method comprises setting a numerical value of a system dynamic data protection level for each system of nodes; and in response to user input, setting a value of a data protection level for one or more data objects in a system, the value being a fixed numerical value or a dynamic value. If the one or more data objects have a dynamic value of the data protection level in a system, the one or more data objects inherit the system dynamic data protection level of the system in which the one or more data objects reside. The value of the data protection level represents a number of copies of data of the one or more data objects to be kept where the one or more data objects reside. | 01-07-2016 |
Melisenda Mcdonald, Westford, MA US
Patent application number | Description | Published |
---|---|---|
20100093107 | POLYMER-PROTEIN SUBSTRATES FOR IMMUNOSORBENT FLUORESCENCE ASSAYS - The present invention relates to antigen-capture substrates useful for orienting capture antibodies for immunosorbent antigen determination. | 04-15-2010 |
Melisenda J. Mcdonald, Westford, MA US
Patent application number | Description | Published |
---|---|---|
20090190135 | CELL CULTURE HYDROGEL WITH pH INDICATOR - The invention provides devices, compositions and methods for maintaining conditions in a cell culture and for measurement of conditions in the cell culture. In particular, the invention provides hydrogel materials, apparatus and methods for several non-invasive techniques of maintaining glucose and pH levels in cell cultures at near-optimal levels and the non-invasive measurement of pH levels in cell cultures. | 07-30-2009 |
Peter D. Mcdonald, Gardner, MA US
Patent application number | Description | Published |
---|---|---|
20110155419 | Enhanced Data cable with cross-twist cabled core profile - A cable exhibiting reduced crosstalk between transmission media includes a core having a profile with a shape which defines spaces or channels to maintain a spacing between transmission media in a finished cable. The core is formed of a conductive material to further reduce crosstalk. A method of producing a cable introduces a core as described above into the cable assembly and imparts a cable closing twist to the assembly. | 06-30-2011 |
Randall J. Mcdonald, Franklin, MA US
Patent application number | Description | Published |
---|---|---|
20110016891 | Cryopump Network - A vacuum network control system includes a plurality of nodes configured for control over operational processes of the system. The plural nodes are configured, in a network ring or other topology, as a selectable master node for controlling the operational processes. Control can be distributed among, and passed between, each of the nodes. Each node on the network monitors adjacent network connectors to detect a fault in the network. In response to a detected fault, a disconnect is mapped to the fault, and the network topology is reconfigured for continued communication among the nodes and with external devices. | 01-27-2011 |
Randy Mcdonald, Franklin, MA US
Patent application number | Description | Published |
---|---|---|
20080255708 | SMART WATER TIMER - A smart water timer which includes a water timer, a receiving unit connected to the water timer, and a moisture sensing unit which is in wireless communication with the receiving unit. The smart water timer can sense when the moisture level in the soil is too moist (based on a user setting) and turn off a water supply to a sprinkler as a result A soil moisture sensing unit is placed in the soil in the area to be watered. The soil moisture sensing unit uses a moisture sensing probe and wirelessly transmits a data signal to the receiver, which is connected to the water timer, indicating whether or not the water timer should be permitted to open a water valve. | 10-16-2008 |
Rob Mcdonald, Cambridge,, MA US
Patent application number | Description | Published |
---|---|---|
20150354006 | MARKERS FOR ACUTE LYMPHOBLASTIC LEUKEMIA - The invention provides methods of detecting a NSD2 mutation in a cancer cell, methods cancer diagnosis and methods of screening for NSD2 inhibitors. | 12-10-2015 |
Rob Mcdonald, Wayland, MA US
Patent application number | Description | Published |
---|---|---|
20150354006 | MARKERS FOR ACUTE LYMPHOBLASTIC LEUKEMIA - The invention provides methods of detecting a NSD2 mutation in a cancer cell, methods cancer diagnosis and methods of screening for NSD2 inhibitors. | 12-10-2015 |
Robert C. Mcdonald, Stow, MA US
Patent application number | Description | Published |
---|---|---|
20090218235 | Gas sensor - Metal-oxide gas sensor. According to one embodiment, the sensor includes a layer or pellet of tungsten trioxide (WO | 09-03-2009 |
20100255353 | Thermal switch material suitable for use in controlling short circuits in lithium-ion batteries and method of making the thermal switch material - A composite thermal switch material suitable for use in controlling short circuits in lithium ion batteries. The switch material comprises a substantially homogeneous matrix of metallic nanoparticles and non-electrically conductive polymeric nanoparticles, the non-electrically conductive polymeric nanoparticles being fused to one another and having a greater thermal expansion coefficient than the metallic nanoparticles, the metallic nanoparticles and the non-electrically conductive polymeric nanoparticles being present in said substantially homogeneous matrix in relative proportions such that the composite thermal switch material is electrically conductive below a switching temperature and is substantially non-electrically conductive at or above the switching temperature. | 10-07-2010 |
20130130126 | ELECTROCHEMICAL CELL FOR HIGH-VOLTAGE OPERATION AND ELECTRODE COATINGS FOR USE IN THE SAME - Electrochemical cell for high-voltage operation and electrode coatings for the same. The electrochemical cell and electrode coatings of the present invention can preferably withstand charging voltages to at least 5-Volts. In one embodiment, the electrochemical cell can include an anode, a cathode, a separator, and an electrolyte, wherein the anode, the cathode, and the separator are operatively associated with the electrolyte. The cathode can include, for example, a mixture of a metal oxide, an elongated carbon structure, and a conductive material. The metal oxide can be, for example, a lithium-nickel-manganese oxide, such as LiNi | 05-23-2013 |
Stephen Mcdonald, Somerville, MA US
Patent application number | Description | Published |
---|---|---|
20080201433 | METRIC-BASED ELECTRONIC MAIL SYSTEM - Described are an electronic communication system and method for routing an electronic mail (email) message. The system includes a database and an email server that receives an email message from a client system over a network. The email message has sender-specified delivery criterion associated therewith. The email server communicates with the database to identify dynamically one or more email addresses of email users based on the delivery criterion associated with the email message. The email server forwards the email message to each dynamically identified email address. | 08-21-2008 |
Stephen Mcdonald, Salem, MA US
Patent application number | Description | Published |
---|---|---|
20140338429 | METHOD OF SEPARATION OF LIPID AND BIOLOGICAL MOLECULAR SPECIES USING HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER - The present invention provides methods of separating, profiling and analyzing molecular species contained within a biological sample using a high purity chromatographic material (HPCM) comprising a chromatographic surface wherein the chromatographic surface comprises a hydrophobic surface group and one or more ionizable modifiers with the proviso that when the ionizable modifier does not contain a Zwitterion, the ionizable modifier does not contain a quaternary ammonium ion moiety. | 11-20-2014 |