Patent application number | Description | Published |
20140116579 | BULK NICKEL-BASED CHROMIUM AND PHOSPHORUS BEARING METALLIC GLASSES WITH HIGH TOUGHNESS - A Ni-based bulk metallic glass forming alloy is provided. The alloy includes Ni | 05-01-2014 |
20140190593 | BULK NICKEL-SILICON-BORON GLASSES BEARING IRON - Ni—Fe—Si—B and Ni—Fe—Si—B—P metallic glass forming alloys and metallic glasses are provided. Metallic glass rods with diameters of at least one, up to three millimeters, or more can be formed from the disclosed alloys. The disclosed metallic glasses demonstrate high yield strength combined with high corrosion resistance, while for a relatively high Fe contents the metallic glasses are ferromagnetic. | 07-10-2014 |
20140238551 | BULK NICKEL-PHOSPHORUS-BORON GLASSES BEARING MANGANESE - The disclosure is directed to Ni—P—B alloys bearing Mn and optionally Cr and Mo that are capable of forming a metallic glass, and more particularly metallic glass rods with diameters at least 1 mm and as large as 5 mm or larger. The disclosure is further directed to Ni—Mn—Cr—Mo—P—B alloys capable of demonstrating a good combination of glass forming ability, strength, toughness, bending ductility, and corrosion resistance. | 08-28-2014 |
20140345755 | BULK NICKEL-BASED CHROMIUM AND PHOSPHORUS BEARING METALLIC GLASSES WITH HIGH TOUGHNESS - A Ni-based bulk metallic glass forming alloy is provided. The alloy includes Ni | 11-27-2014 |
20150047755 | BULK NICKEL-PHOSPHORUS-BORON GLASSES BEARING MANGANESE, NIOBIUM AND TANTALUM - The present disclosure is directed to Ni—P—B alloys and glasses containing small fractions of Nb and Ta and optionally Mn. Over a specific range, the alloys are capable of forming bulk metallic glasses having critical casting thickness in excess of 1 mm. In one embodiment, compositions with a Mn content of between 3 and 4 atomic percent, Nb content of about 3 atomic percent, B content of about 3 atomic percent, and P content of about 16.5 atomic percent, where the balance in Ni, were capable of forming bulk metallic glass rods with diameters as large as 5 mm or larger. In another embodiment, Ni-based compositions with a Mn content of between 5 and 7 atomic percent, Ta content of between 1 and 2 atomic percent, B content of about 3 atomic percent, and P content of about 16.5 atomic percent, where the balance in Ni, were capable of forming bulk metallic glass rods with diameters as large as 5 mm or larger. | 02-19-2015 |
20150096652 | BULK NICKEL-SILICON-BORON GLASSES BEARING IRON - Ni—Fe—Si—B and Ni—Fe—Si—B—P metallic glass forming alloys and metallic glasses are provided. Metallic glass rods with diameters of at least one, up to three millimeters, or more can be formed from the disclosed alloys. The disclosed metallic glasses demonstrate high yield strength combined with high corrosion resistance, while for a relatively high Fe contents the metallic glasses are ferromagnetic. | 04-09-2015 |
20150159240 | MELT FLUXING METHOD FOR IMPROVED TOUGHNESS AND GLASS-FORMING ABILITY OF METALLIC GLASSES AND GLASS-FORMING ALLOYS - A method of fluxing the melt of metallic glass forming alloys is provided. Alloys fluxed according to the disclosed methods demonstrate a critical rod diameter that does not vary by more than 60% when varying the melt overheating. Moreover, metallic glasses produced from alloys fluxed according to the disclosed methods demonstrate notch toughness that does not vary by more than 30% when varying the melt overheating. Furthermore, a method by which used feedstock is purified such that its toughness and glass forming ability is restored for reuse is also disclosed. Recycled feedstock purified according to the disclosed method demonstrates critical rod diameter that is at least 70% of the critical rod diameter of the as-formed alloy. Also, metallic glasses produced from recycled feedstock demonstrate notch toughness of at least 70% of the notch toughness of a metallic glass produced from the as-formed alloy. | 06-11-2015 |
20150176111 | BULK NICKEL-IRON-BASED, NICKEL-COBALT-BASED AND NICKEL-COPPER BASED GLASSES BEARING CHROMIUM, NIOBIUM, PHOSPHORUS AND BORON - Ni—Fe, Ni—Co, and Ni—Cu-based bulk metallic glass forming alloys are provided. The alloys have critical rod diameters of at least 1 mm and in some instances at least 11 mm. The alloys have composition according to Ni | 06-25-2015 |
Patent application number | Description | Published |
20110143367 | ANTIBODIES AGAINST APRIL AS BIOMARKERS FOR EARLY PROGNOSIS OF LYMPHOMA PATIENTS - The invention relates to antibodies directed against APRIL (A Proliferation Inducing TNF Ligand, also known as TALL-2), in particular the monoclonal antibody Aprily-2, hybridoma cells producing monoclonal antibody Aprily-2, and the use of a combination of an antibody against membrane-anchored APRIL and Aprily-2 in the diagnosis of B cell lymphoma resistance to treatment and the prognosis of clinical development of Diffuse Large B-Cell (DLBCL) lymphoma from high risk patients (>60 years and International Prognostic Index >2). An amino acid sequence GTGGPSQNGEGYP called Stalk, useful in the preparation of antibodies, is described. | 06-16-2011 |
20130012518 | BICYCLIC COMPOUNDS AND THEIR USES AS DUAL C-SRC / JAK INHIBITORS - The present invention relates to substituted aromatic bicyclic compounds containing pyrimidine and pyridine rings of formula (I) having the structure as well as pharmaceutically acceptable salts thereof. The compounds of the present invention are useful as tyrosine kinase inhibitors, preferably SRC family kinases (SFKs) inhibitors, in particular as multi SFK/JAK. kinases inhibitors and even preferably as dual c-SRC/JAK kinases inhibitors, thereby inhibiting the STAT3 activation and therefore abnormal growth of particular cell types. Notably, the compounds of the present invention are useful for the treatment or inhibition of certain diseases that are the result of deregulation of STAT3. | 01-10-2013 |
20130143895 | BICYCLIC COMPOUNDS AND THEIR USES AS DUAL C-SRC / JAK INHIBITORS - The present invention relates to substituted aromatic bicyclic compounds containing pyrimidine and pyridine rings of formula (I) having the structure as well as pharmaceutically acceptable salts thereof. The compounds of the present invention are useful as tyrosine kinase inhibitors, preferably SRC family kinases (SFKs) inhibitors, in particular as multi SFK/JAK. kinases inhibitors and even preferably as dual c-SRC/JAK kinases inhibitors, thereby inhibiting the STAT3 activation and therefore abnormal growth of particular cell types. Notably, the compounds of the present invention are useful for the treatment or inhibition of certain diseases that are the result of deregulation of STAT3. | 06-06-2013 |