Patent application number | Description | Published |
20090193732 | Method and System for Twisting Building Construction - A structure and method of construction for a building, includes a core wall structure, a plurality of support walls attached to the core wall structure and cantilevered from the core wall structure, a plurality of floor structures arranged vertically and attached to the core wall structure so that each floor structure of the plurality of floor structures is supported from below by a first set of the plurality of support walls and from above by a second set of the plurality of support walls, a position of the second set of the plurality of support walls radially offset from a position of the first set of the plurality of support walls, and a plurality of openings in the core wall, wherein at least one opening is provided between any two successive floor structures and alternating openings in a vertical direction are arranged to align along an angle of vertical offset. | 08-06-2009 |
20110219712 | METHOD AND SYSTEM FOR TWISTING BUILDING STRUCTURE - A structure and method of designing and constructing a building that includes a core wall structure, a plurality of support walls attached to and cantilevered from the core wall structure, a plurality of floor structures arranged vertically and attached to the core wall structure so that each floor structure of the plurality of floor structures is supported from below by a first set of the plurality of support walls and from above by a second set of the plurality of support walls, a position of the second set of the plurality of support walls radially offset from a position of the first set of the plurality of support walls, and a plurality of openings in the core wall, wherein at least one opening is provided between any two successive floor structures and alternating openings in a vertical direction are arranged to align along an angle of vertical offset. | 09-15-2011 |
20140150360 | METHOD AND SYSTEM FOR TWISTING BUILDING STRUCTURE - A structure and method of designing and constructing a building that includes a core wall structure, a plurality of support walls attached to and cantilevered from the core wall structure, a plurality of floor structures arranged vertically and attached to the core wall structure so that each floor structure of the plurality of floor structures is supported from below by a first set of the plurality of support walls and from above by a second set of the plurality of support walls, a position of the second set of the plurality of support walls radially offset from a position of the first set of the plurality of support walls, and a plurality of openings in the core wall, wherein at least one opening is provided between any two successive floor structures and alternating openings in a vertical direction are arranged to align along an angle of vertical offset. | 06-05-2014 |
Patent application number | Description | Published |
20090094012 | METHODS AND SYSTEMS FOR GRAND CANONICAL COMPETITIVE SIMULATION OF MOLECULAR FRAGMENTS - Methods and systems for analyzing a macromolecule for potential binding sites are disclosed. Multiple molecular species and a free energy value may be selected. An operation for a molecular fragment of one of the molecular species may be selected from insertion, deletion and movement operations. The selected operation may be performed on a computer representation of an instance of a molecular fragment at one of a plurality of binding sites based on a grand canonical ensemble probability density function associated with the selected operation. Information may be stored pertaining to the plurality of binding sites. The operation selecting, performing and information storing operations may be performed multiple times. Multiple occupation probabilities may be provided based on the stored information. The occupation probabilities may include, for each molecular species, a probability that an instance of a molecular fragment of the molecular species resides at a binding site. | 04-09-2009 |
20090171642 | METHODS AND SYSTEMS FOR IMPROVING FREE ENERGY ESTIMATION OF FRAGMENTS - Methods and systems for estimating the free energy of molecules from a plurality of fragments are disclosed. A number of poses for each fragment in an unbound state and a sum of the free energy values for each fragment may be determined. A number of acceptable poses for each of a plurality of fragments when bound may also be determined. An entropy loss may be estimated based on at least the number of acceptable poses for each of the plurality of fragments when bound and the number of poses for each fragment in an unbound state. A free energy value may be determined for the plurality of fragments when bound based on the entropy loss. | 07-02-2009 |
20110130968 | Method for computing ligand - host binding free energies - Methods and systems for computing the binding free energy of a ligand to a host are disclosed. The method entails selecting random poses of a ligand, including translation, rotation, and conformation, and computing the ligand-host interaction energy. The poses are accepted or rejected based on the Metropolis criteria. The entropies of interaction are estimated from the log of the ratio of accepted poses to attempted poses. The free energy of the entire sampling region, and of sub-regions of the binding region, can be accumulated by storing the energies and acceptance ratios for both the entire region and the sub regions. In order to better shape the protein to the ligand, energy minimization of the host atoms in the region of the ligand is carried out in the presence of the lowest free-energy pose of the ligand, optionally preceded by random perturbation of the Cartesian coordinates of the host atoms in the vicinity of the ligand. | 06-02-2011 |
Patent application number | Description | Published |
20110199225 | USE OF TOKEN SWITCH TO INDICATE UNAUTHORIZED MANIPULATION OF A PROTECTED DEVICE - An apparatus to indicate unauthorized manipulation of at least one protected device enclosed in a housing is provided. The apparatus includes a structure attached to a first portion of the housing and a token switch attached to a second portion of the housing. The token switch is operably positioned with reference to the structure. The token switch includes a plunger, and a register programmed with a value. The register is communicatively coupled with a processor in a circuit. The circuit is communicatively coupled to drive the device. The structure, the token switch, and the circuit are internal to the housing when the housing is in a closed position. The plunger and the structure are positioned to generate a current when the housing is opened. The programmed value in the register is changed by the generated current and the processor takes an action responsive to the change in the programmed value. | 08-18-2011 |
20130081860 | MITIGATION OF BLOCK BENDING IN A RING LASER GYROSCOPE CAUSED BY THERMAL EXPANSION OR COMPRESSION OF A CIRCUIT BOARD - An apparatus includes a sheet of circuit board material, at least one electrically conductive trace positioned on the sheet of circuit board material, and at least one electrically conductive contact pad positioned on the sheet of circuit board material and coupled to the at least one electrically conductive trace. The apparatus further includes at least one deformation point configured to absorb stresses developed in the sheet of circuit board material when the sheet of circuit board material experiences resistance to expansion or compression caused by connection to an object resisting expansion or compression. | 04-04-2013 |
20130083326 | TEMPERATURE SENSOR ATTACHMENT FACILITATING THERMAL CONDUCTIVITY TO A MEASUREMENT POINT AND INSULATION FROM A SURROUNDING ENVIRONMENT - A temperature sensor package includes a temperature sensor having a first side and a second side, wherein the first side of the temperature sensor includes an active region configured for coupling with a target area for temperature measurement of an object. The temperature sensor package further includes a circuit board having a first side and a second side, the first side of the circuit board coupled to the second side of the temperature sensor, wherein the circuit board provides thermal insulation between the active region of the temperature sensor and an environment on the second side of the circuit board. | 04-04-2013 |
20160042906 | PARTIALLY INSULATED CATHODE - A partially-insulated cathode for exciting plasma in a plasma chamber is provided. The partially-insulated cathode includes a conductive structure enclosing a cavity having a cavity surface and an insulating material contiguously covering a portion of the cavity surface from the cavity opening up to an insulation height that is less than a cavity height. Cross-sections of the cavity in X-Y planes have at least one respective cavity-width. A cavity opening has a diameter less than a minimum cavity-width of the at least one cavity-width. | 02-11-2016 |