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Matthew B.

Matthew B. Boxer, Point Of Rocks, MD US

Patent application numberDescriptionPublished
20110195958ACTIVATORS OF HUMAN PYRUVATE KINASE - Disclosed are pyruvate kinase M2 activators, which are bis sulfonamide piperazinyl and piperidinyl compounds of Formula (I), 2,4-disubstituted 4H-thieno[3,2-c]pyrrole-2-(substituted benzyl)pyridazin-3(2H)-ones of Formula (II) and 6-(3,4-dimethylphenylaminosulfonyl)-3,4-dihydro-1H-quinolin-2-one of formula (III), wherein L, R08-11-2011

Matthew B. Delavan, Rochester, MI US

Patent application numberDescriptionPublished
20080256951COMBUSTION ENGINE BREATHING SYSTEM INCLUDING A COMPRESSOR VALVE FOR A BITURBO WITH CYLINDER DEACTIVATION - One embodiment of the invention includes a combustion engine breathing system including a compressor valve for use with a biturbo system and cylinder deactivation10-23-2008
20110094222Turbine regulating valve system - A regulated two-stage turbocharger system is described. The turbocharger system includes high-pressure and low-pressure turbocharger units in communication with one another. The turbocharger system includes a valve system having valve members that are independently controllable so as to selectively control the gas flow into the turbine portions of the high-pressure turbocharger and the low-pressure turbocharger units. The valve members are asymmetric, e.g., they possess differing areas (e.g., perimeters, diameters and/or the like) with respect to one another.04-28-2011

Patent applications by Matthew B. Delavan, Rochester, MI US

Matthew B. Donatucci, Bethel, CT US

Patent application numberDescriptionPublished
20100059694PRESSURE-BASED GAS DELIVERY SYSTEM AND METHOD FOR REDUCING RISKS ASSOCIATED WITH STORAGE AND DELIVERY OF HIGH PRESSURE GASES - Apparatus and method for dispensing a gas using a gas source coupled in selective flow relationship with a gas manifold. The gas manifold includes flow circuitry for discharging gas to a gas-using zone, and the gas source includes a pressure-regulated gas source vessel containing the gas at superatmospheric pressure. The pressure-regulated gas source vessel can be arranged with a pressure regulator at or within the vessel and a flow control valve coupled in flow relationship to the vessel, so that gas dispensed from the vessel flows through the regulator prior to flow through the flow control valve, and into the gas manifold. The apparatus and method permit an enhancement of the safety of storage and dispensing of toxic or otherwise hazardous gases used in semiconductor processes.03-11-2010

Patent applications by Matthew B. Donatucci, Bethel, CT US

Matthew B. Jarpe, Quincy, MA US

Patent application numberDescriptionPublished
20090017044Antibodies to the Human Prolactin Receptor - This invention provides antibodies to the prolactin receptor, particularly the human prolactin receptor. Preferred antibodies are capable of blocking prolactin binding to the prolactin receptor, inhibiting signaling through the prolactin receptor, and/or inhibiting proliferation of cancer cells induced by prolactin. Also provided are nucleic acids encoding the antibodies, vectors and host cells comprising the nucleic acids, and uses of the antibodies and nucleic acids.01-15-2009

Matthew B. Mendelow, Austin, TX US

Patent application numberDescriptionPublished
20100064128METHOD AND SYSTEM FOR RESTORING SYSTEM CONFIGURATION AFTER DISORDERLY SHUTDOWN - Disclosed are techniques for recovering system configuration settings, such as remote management, of an information handling system following a disorderly shutdown. A restart controller detects a disorderly shutdown of an information handling system and, in response, sets a disorderly shutdown flag and restarts the information handling system. During the restart, the basic input/output system (BIOS) checks the disorderly shutdown flag as part of its power-on housekeeping. In response to determining the disorderly shutdown flag has been set, the BIOS reconfigures the system configuration settings, such as the power management scheme, of the information handling system so as to enable one or more remote wake mechanisms, such as wake-on-LAN or wake-on-ring. The BIOS then performs an orderly shutdown of the information handling system to place the information handling system in a low-power state, from which the information handling system can be awoken via the remote wake mechanism.03-11-2010

Matthew B. Murphy, San Francisco, CA US

Patent application numberDescriptionPublished
20100233030Western Blot by Incorporating an Affinity Purification Zone - An upstream affinity purification region is used to bind one or more component of interest in a mixture of components prior to separating the mixture of components. Detection of the separated components and a released component of interest provide identification of the component of interest. In addition, post separation dilution is optionally used to improve detection of the mixture of components and the released component of interest. Microfluidic devices and systems suitable for performing such analyses are also provided.09-16-2010

Matthew B. Oefinger, Santa Fe, NM US

Patent application numberDescriptionPublished
20100210953System and method for heart and activity monitoring - A system and method determining physiological status of a patient. A determination is made whether the patient is sleeping. The amplitude and change in voltage over time of any intramyocardial electrogram is measured for a right ventricle and a left ventricle of a heart of the patient for a predefined number of heartbeats at a specified time interval in response to determining the patient is asleep. The measurements are averaged for the right ventricle and left ventricle. The averaged measurements are transmitted to a receiver for communication to an intended recipient.08-19-2010

Matthew B. Schabath, Houston, TX US

Patent application numberDescriptionPublished
20100173289Methods for Assessing Cancer Susceptibility to Carcinogens in Tobacco Products - The present invention demonstrates the differential sensitivity of PBLs from lung cancer patients and healthy controls to NNK-induced genetic damage. The data provide convincing evidence that the preferred CBMN assay is a robust test for detection of this sensitivity and yields results that are a good predictor of, for example, lung cancer risk. The simplicity, rapidity, and sensitivity of the CBMN test make it a valuable tool for screening and, for example, prioritizing potential cases for early detection of the disease.07-08-2010

Matthew B. Scudiere, Oak Ridge, TN US

Patent application numberDescriptionPublished
20120043930OFF-RESONANCE FREQUENCY OPERATION FOR POWER TRANSFER IN A LOOSELY COUPLED AIR CORE TRANSFORMER - A power transmission system includes a loosely coupled air core transformer having a resonance frequency determined by a product of inductance and capacitance of a primary circuit including a primary coil. A secondary circuit is configured to have a substantially same product of inductance and capacitance. A back EMF generating device (e.g., a battery), which generates a back EMF with power transfer, is attached to the secondary circuit. Once the load power of the back EMF generating device exceeds a certain threshold level, which depends on the system parameters, the power transfer can be achieved at higher transfer efficiency if performed at an operating frequency less than the resonance frequency, which can be from 50% to 95% of the resonance frequency.02-23-2012

Matthew B. Smittel, Allen, TX US

Patent application numberDescriptionPublished
20100274994PROCESSOR OPERATING MODE FOR MITIGATING DEPENDENCY CONDITIONS - Various techniques for mitigating dependencies between groups of instructions are disclosed. In one embodiment, such dependencies include “evil twin” conditions, in which a first floating-point instruction has as a destination a first portion of a logical floating-point register (e.g., a single-precision write), and in which a second, subsequent floating-point instruction has as a source the first portion and a second portion of the same logical floating-point register (e.g., a double-precision read). The disclosed techniques may be applicable in a multithreaded processor implementing register renaming. In one embodiment, a processor may enter an operating mode in which detection of evil twin “producers” (e.g., single-precision writes) causes the instruction sequence to be modified to break potential dependencies. Modification of the instruction sequence may continue until one or more exit criteria are reached (e.g., committing a predetermined number of single-precision writes). This operating mode may be employed on a per-thread basis.10-28-2010

Matthew B. Smittle, Allen, TX US

Patent application numberDescriptionPublished
20100332804UNIFIED HIGH-FREQUENCY OUT-OF-ORDER PICK QUEUE WITH SUPPORT FOR SPECULATIVE INSTRUCTIONS - Systems and methods for efficient picking of instructions for out-of-order issue and execution in a processor. In one embodiment, a processor comprises a unified pick queue that is dynamically allocated. Each entry is configured to store age and dependency information relative to other decoded instructions. Also, each entry stores a picked field, which when asserted indicates the decoded instruction has already been picked for out-of-order issue and execution. When asserted, a trigger field indicates a result of a corresponding decoded instruction will be available a predetermined number of clock cycles afterward. A younger instruction dependent on a result of an older instruction is ready to be picked before the result of the older instruction is available. In this case, the older instruction has asserted picked and trigger fields.12-30-2010
20100332806DEPENDENCY MATRIX FOR THE DETERMINATION OF LOAD DEPENDENCIES - Systems and methods for identification of dependent instructions on speculative load operations in a processor. A processor allocates entries of a unified pick queue for decoded and renamed instructions. Each entry of a corresponding dependency matrix is configured to store a dependency bit for each other instruction in the pick queue. The processor speculates that loads will hit in the data cache, hit in the TLB and not have a read after write (RAW) hazard. For each unresolved load, the pick queue tracks dependent instructions via dependency vectors based upon the dependency matrix. If a load speculation is found to be incorrect, dependent instructions in the pick queue are reset to allow for subsequent picking, and dependent instructions in flight are canceled. On completion of a load miss, dependent operations are re-issued. On resolution of a TLB miss or RAW hazard, the original load is replayed and dependent operations are issued again from the pick queue.12-30-2010
20110029978DYNAMIC MITIGATION OF THREAD HOGS ON A THREADED PROCESSOR - Systems and methods for efficient thread arbitration in a processor. A processor comprises a multi-threaded resource. The resource may include an array 8of entries which may be allocated by threads. A thread arbitration table corresponding to a given thread stores a high and a low threshold value in each table entry. A thread history shift register (HSR) indexes the table, wherein each bit of the HSR indicates whether the given thread is a thread hog. When the given thread has more allocated entries in the array than the high threshold of the table entry, the given thread is stalled from further allocating array entries. Similarly, when the given thread has fewer allocated entries in the array than the low threshold of the selected table entry, the given thread is permitted to allocate entries. In this manner, threads that hog dynamic resources can be mitigated such that more resources are available to other threads that are not thread hogs. This can result in a significant increase in overall processor performance.02-03-2011
20110078697OPTIMAL DEALLOCATION OF INSTRUCTIONS FROM A UNIFIED PICK QUEUE - Systems and methods for efficient out-of-order dynamic deallocation of entries within a shared storage resource in a processor. A processor comprises a unified pick queue that includes an array configured to dynamically allocate any entry of a plurality of entries for a decoded and renamed instruction. This instruction may correspond to any available active threads supported by the processor. The processor includes circuitry configured to determine whether an instruction corresponding to an allocated entry of the plurality of entries is dependent on a speculative instruction and whether the instruction has a fixed instruction execution latency. In response to determining the instruction is not dependent on a speculative instruction, the instruction has a fixed instruction execution latency, and said latency has transpired, the circuitry may deallocate the instruction from the allocated entry.03-31-2011

Matthew B. Talpis, Austin, TX US

Patent application numberDescriptionPublished
20090116947METHOD AND SYSTEM FOR ASSISTED OBJECT HANDLING IN DANGEROUS ENVIRONMENTS - A system for remote object handling including a public safety vehicle having a front portion. An articulated arm has a first end and a second end distinct from the first end, the arm being coupled to the front portion at the first end, and has at least one pivot disposed between the first end and the second end. A gripping element is removably coupled to the second end, wherein the gripping element is one of a pincer device, a hand device having at least three fingers or a shovel. A video camera is also coupled to the second end. An arm control is disposed within the vehicle and is operable to control the operation of the arm, the manipulator and the video camera, and a video interface is coupled to the video camera which is operable to display output from the video camera.05-07-2009