Patent application number | Description | Published |
20080207624 | Therapeutic Agent for Bh4-Responsive Hyperphenylalaninemia - A pharmaceutical preparation containing sapropterin hydrochloride can be used to administer sapropterin hydrochloride, an effective therapeutic agent for the treatment of tetrahydrobiopterin-responsive hyperphenylalaninemia, to patients of a wide range of ages, ranging from infants to adults, in a single preparation. One specific example is a pharmaceutical preparation for the treatment of BH4-responsive hyperphenylalaninemia provided in the form of granule, fine granule, or dry syrup, comprising sapropterin hydrochloride as an active ingredient; a flavoring agent; a coloring agent which is stable to acid and oxidation; and ascorbic acid or L-cysteine hydrochloride as a stabilizer, wherein the preparation has a moisture content (weight loss on drying) of 0.9% or less. Also provided is the pharmaceutical preparation in which the amount of sapropterin hydrochloride is from 2.5 to 20 wt %. | 08-28-2008 |
20110077195 | LIQUID PREPARATION OF PHYSIOLOGICALLY ACTIVE PEPTIDE - An effective liquid preparation achieves high bioavailability (BA) of physiologically active peptides or proteins, including ghrelins, that are administered as drugs. Also provided is a method for improving the BA of physiologically active peptides or proteins, including ghrelins, that are subcutaneously injected in aqueous solutions. The liquid preparation contains: a physiologically active peptide or protein, such as ghrelins, as an active ingredient; an acid solution including one or a combination of two or more selected form the group consisting of acetic acid, lactic acid, phosphoric acid, glycine, citric acid, hydrochloric acid, propionic acid, butyric acid, benzoic acid and salts thereof; an alcohol; and a polar organic liquid including one or a combination of two or more selected from the group consisting of N-methyl-2-pyrrolidone, dimethylformamide, dimethylsulfoxide and methylparaben. | 03-31-2011 |
Patent application number | Description | Published |
20110077195 | LIQUID PREPARATION OF PHYSIOLOGICALLY ACTIVE PEPTIDE - An effective liquid preparation achieves high bioavailability (BA) of physiologically active peptides or proteins, including ghrelins, that are administered as drugs. Also provided is a method for improving the BA of physiologically active peptides or proteins, including ghrelins, that are subcutaneously injected in aqueous solutions. The liquid preparation contains: a physiologically active peptide or protein, such as ghrelins, as an active ingredient; an acid solution including one or a combination of two or more selected form the group consisting of acetic acid, lactic acid, phosphoric acid, glycine, citric acid, hydrochloric acid, propionic acid, butyric acid, benzoic acid and salts thereof; an alcohol; and a polar organic liquid including one or a combination of two or more selected from the group consisting of N-methyl-2-pyrrolidone, dimethylformamide, dimethylsulfoxide and methylparaben. | 03-31-2011 |
20120264691 | MEDICAL COMPOSITIONS CONTAINING GHRELIN - It is provided a pharmaceutical composition stably containing ghrelin or its derivative, which is an endogenous growth hormone secretagogue (GHS) to a growth hormone secretagogue-receptor (GHS-R), comprising a aqueous solution containing the ghrelins having pH range of 2 to 7, wherein the aqueous solution having pH range of 2 to 7 is a buffer solution, especially, glycine hydrochloride buffer, acetate buffer, citrate buffer, lactate buffer, phosphate buffer, citric acid-phosphate buffer, phosphate-acetate-borate buffer or phthalate buffer, and the concentration of the ghrelins in the solution is from 0.03 nmol/mL to 6 μmol/mL. | 10-18-2012 |
Patent application number | Description | Published |
20090048178 | LPS OR LIPID A BINDING AGENT AND NOVEL PEPTIDE - A lipopolysaccharide (LPS) and/or lipid A binding agent is provided. The LPS and/or lipid A binding agent contains an LPS and/or lipid A binding peptide, such as a peptide comprising an amino acid sequence of XYSSS (X=K, R, or H), or a derivative thereof, as an active ingredient. The LPS and/or lipid A binding agent is useful as, for example, an LPS and/or lipid A neutralizing agent or an LPS and/or lipid A removing agent. | 02-19-2009 |
20110098214 | LPS OR LIPID A BINDING AGENT AND NOVEL PEPTIDE - A lipopolysaccharide (LPS) and/or lipid A binding agent is provided. The LPS and/or lipid A binding agent contains an LPS and/or lipid A binding peptide, such as a peptide comprising an amino acid sequence of XYSSS (X=K, R, or H), or a derivative thereof, as an active ingredient. The LPS and/or lipid A binding agent is useful as, for example, an LPS and/or lipid A neutralizing agent or an LPS and/or lipid A removing agent. | 04-28-2011 |
Patent application number | Description | Published |
20090050691 | Electronic Money Terminal - The present invention provides an electronic money terminal which alone can handle multiple types of electronic money services. Since the electronic money terminal has a storage unit for storing a plurality of settlement processing programs each corresponding to one electronic money service, a selection unit for allowing a user to select an electronic money service that is used for settlement processing, and a control unit for causing a settlement processing program to be executed, which corresponds to the electronic money service selected by an input unit, the single electronic money terminal can perform settlement processing using the multiple types of electronic money services. As a result, since the number of the electronic money terminals in the entire system can be reduced, costs required to introduce the settlement systems corresponding to the electronic money services can be reduced. | 02-26-2009 |
20090095805 | ELECTRONIC MONEY PAYING-IN SYSTEM - The present invention provides an electronic money paying-in system that can easily update information used for an electronic money paying-in process. As the present invention is provided with an electronic money management server for acquiring a paying-in amount that has been input to an electronic money charger and also sending a paying-in processing command for adding the paying-in amount to an electronic money balance on an IC card to the IC card via the electronic money charger, it needs to store information used for processing of depositing electronic money like the paying-in processing command only in the electronic money management server and it can easily update the information used for an electronic money paying-in process just by performing maintenance on the server. Therefore, as the information used for an electronic money paying-in process can be easily updated, maintenance operation can be easily performed on the electronic money charger. | 04-16-2009 |
20100117795 | INFORMATION TERMINAL - An information terminal wherein a simple operation can provide appropriate contents. An information terminal ( | 05-13-2010 |
20110221577 | COMMUNICATION INFORMATION DISPLAY SYSTEM - A commodity information display apparatus includes a shelf on which a commodity is displayed, and a display unit for displaying the commodity information about the commodity. The commodity information about the commodity related to an RFID tag detected by an antenna and a read device is acquired in advance from a store computer and stored in a storage unit. When the commodity information is displayed, the information is acquired from the storage unit, and displayed on the display unit. | 09-15-2011 |
Patent application number | Description | Published |
20110056236 | REFRIGERATION CYCLE - In a refrigeration cycle comprising a compressor, a condenser, a pressure reduction and expansion means, and an evaporator, R1234yf is used as the refrigerant, the refrigerant at the exit side of the evaporator is controlled in a superheated condition, and the refrigeration cycle is operated in a range of 5 to 16 degrees of superheat, and preferably in a range of 10 to 16 degrees of superheat. When the refrigerant used is changed to the new refrigerant R1234yf, while high advantage for improving the coefficient of performance can be achieved, the rise in temperature of the discharged refrigerant is appropriately suppressed so that deterioration of refrigerating machine oil in the refrigerant can be prevented, and a high-efficiency operation can be realized as the entirety of the refrigeration cycle. | 03-10-2011 |
20110113819 | Refrigeration Cycle - Provided is a refrigeration cycle wherein a compressor, a condenser, a depressurizing/expanding means and an evaporator are provided. The refrigeration cycle uses R1234 as a refrigerant, and has an oil separating means, which forcibly separates the refrigerant and oil one from the other, in a two-phase separation region wherein the refrigerant and the oil exist in a separated state without being dissolved with each other. The refrigerant and the oil can be forcibly separated suitably at a suitable position even when the refrigerant is changed to the new refrigerant R1234yf, and the refrigeration cycle can be operated at a high efficiency as a whole. | 05-19-2011 |
20110120175 | Refrigeration Circuit - A refrigeration circuit provided with a scroll compressor for compressing a refrigerant, characterized in that R1234yf is used as the refrigerant and a polyol ester is used as a lubricating oil for the refrigeration circuit. In this refrigeration circuit, an undesirable reaction product can be prevented from accumulating. The refrigeration circuit hence is reduced in environmental burden and has the same operating stability as in conventional ones. | 05-26-2011 |
20120096878 | Refrigeration Circuit and Method for Improving Same - Disclosed is a refrigeration circuit in which a scroll compressor is used as a compressor, an unsaturated fluorinated hydrocarbon refrigerant is used as a refrigerant, and an ether-based lubricant such as a polyalkylene glycol is used as a refrigeration machine oil, and wherein a wax-like solid material, which causes clogging of the refrigeration circuit or deterioration of the refrigeration performance, is prevented from being generated. Specifically, a wax-like solid material is prevented from being generated in a refrigeration circuit by adding a lubricant type component having no polyoxyalkylene structure such as an ester-based lubricant, an alcohol-based friction modifier, an olefin-based friction modifier, a polyolefin-based lubricant, an alkyl aromatic lubricant or a silicone-based lubricant, or a metal deactivation agent such as benzotriazole to an ether-based lubricant such as a polyalkylene glycol. | 04-26-2012 |
20130068437 | Tube for Heat Exchanger, Heat Exchanger, and Method for Manufacturing Tube for Heat Exchanger - Provided is a tube for a heat exchanger in which drainage performance of the tube and the fin is improved while preventing the brazing failure. That is, provided is a tube ( | 03-21-2013 |
20130068438 | Heat Exchanger - Provided is a heat exchanger in which drainage performance of a tube and a fin is improved while preventing reduction in heat exchange efficiency. The heat exchanger includes: a tube having flat surfaces opposed to each other at a predetermined interval; and a fin including a bent portion and a flat portion which are alternately formed in a longitudinal direction, the bent portion being joined to the opposing flat surfaces of the tube. The fin has a predetermined lateral range (bent portion) in the bent portion which is brought into contact with one of the opposing flat surfaces, the predetermined lateral range being bent toward another of the opposing flat surfaces and joined to the another of the opposing flat surfaces, thereby forming a communication path. | 03-21-2013 |
20150323225 | Heat Exchanger And Heat Pump System Using Same - A main core portion ( | 11-12-2015 |