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Mathai Mammen
Mathai Mammen, San Mateo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090306134 | Muscarinic receptor antagonists - Disclosed are multibinding compounds which are muscarinic receptor antagonists. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a muscarinic receptor antagonist or an allosteric modulator provided that at least one of said ligand is a muscarinic receptor antagonist. The multibinding compounds of this invention are useful in the treatment and prevention of diseases such as chronic obstructive pulmonary disease, chronic bronchitis, irritable bowel syndrome, urinary incontinence, and the like. | 12-10-2009 |
Mathai Mammen, Redwood City CA
Mathai Mammen, Redwood Shores, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090018165 | Biphenyl compounds useful as muscarinic receptor antagonists - This invention provides compounds of formula I: | 01-15-2009 |
| 20090023777 | Substituted 4-amino-benzylpiperidine compounds - This invention provides 4-amino-1-benzylpiperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome, asthma and chronic obstructive pulmonary disease, using such compounds. | 01-22-2009 |
| 20090048299 | Biphenyl compounds useful as muscarinic receptor antagonists - This invention provides compounds of formula I: | 02-19-2009 |
| 20090082397 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - This invention provides compounds of formula I: | 03-26-2009 |
| 20090088453 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - This invention provides compounds of formula I: | 04-02-2009 |
| 20090176767 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - This invention provides compounds of formula I: | 07-09-2009 |
Mathai Mammen, Redwood City, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090076026 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS - The invention provides compounds of formula I: | 03-19-2009 |
| 20090111737 | Novel antibacterial agents - This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands has | 04-30-2009 |