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Mateja
Mateja Burjak, Ljubljana SI
| Patent application number | Description | Published |
|---|---|---|
| 20100297227 | PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE ACTIVE AGENT AND A BINDER, WHICH SWELLS IN AN ACIDIC MEDIA - The invention relates to a pharmaceutical composition, which comprises at least one active agent and which further comprises a binder and/or a retarding agent, wherein the binder swells in an acidic medium, and the retarding agent retards the release of the active agent in an acidic or alkaline medium. | 11-25-2010 |
Mateja Burjak, Vrhnika SI
| Patent application number | Description | Published |
|---|---|---|
| 20100172969 | HOT-MELT MICROPELLETS - The present invention provides a method of making solid micropellets of which at least 75% by weight have a diameter less than 500 μm comprising (i) melting one or more binders; and (ii) combining the one or more binders melted in step (i) with a pharmaceutically active ingredient to form solid micropellets. Solid micropellets obtainable by this method are also provided. The invention has particular utility for improving the solubility of poorly water-soluble pharmaceutically active ingredients. | 07-08-2010 |
Mateja Mancek Keber, Ljubljana SI
| Patent application number | Description | Published |
|---|---|---|
| 20080269317 | Compounds for Covalent Binding to MD-2 and Effect on the Immune Response - Compounds having a hydrophobic group with a group and capable of reacting with the cysteine residue for the binding to protein MD-2 are disclosed. The compounds are capable of covalently binding to MD-2, which can be either free or in the complex with other molecules. The compounds are capable of replacing other ligands or preventing a binding of other ligands, especially bacterial endotoxin (lipopolysaccharide-LPS), which can otherwise lead towards unwanted activation of the immune response and acute or chronic inflammatory diseases. | 10-30-2008 |
Mateja Novak Stagoj, Ljubljana SI
| Patent application number | Description | Published |
|---|---|---|
| 20090047708 | HIGHLY PRODUCTIVE RECOMBINANT YEAST STRAINS WITH MODIFIED GALACTOSE-REGULATED TRANSCRIPTION - A recombinant yeast cell with modified galactose-regulated transcription, a use of such yeast cell, and products made using such yeast cell are disclosed. In such a recombinant yeast cell, a chromosomal gene encoding an enzyme for transformation of a transcription inductor into an inactive product is replaced by a gene encoding a transcription factor for a galactose-inducible promoter. Examples of yeast cells include those from Saccharomycetaceae or Cryptococcaceae families or from the | 02-19-2009 |
Mateja Salobir, Ljubljana SI
| Patent application number | Description | Published |
|---|---|---|
| 20090012150 | Stablized Pharmaceutical Composition Comprising an Amorphous Active Substance - The invention relates to the pharmaceutical composition comprising the amorphous active substance which is atorvastatin calcium. The process of stabilization of the pharmaceutical composition comprising the pharmaceutical formulation with amorphous atorvastatin calcium, the process of stabilization of the pharmaceutical formulation comprising amorphous atorvastatin calcium and the process of stabilization of atorvastatin calcium in an amorphous form is described. | 01-08-2009 |