Massaccesi
Franco Massaccesi, Grancona (vicenza) IT
Patent application number | Description | Published |
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20110021793 | PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for reducing a compound of formula (I) wherein X is halogen, a hydroxy group, an alkylsulfoniloxy group or an arylsulfonyloxy group; to give a compound of formula (II) as a di-astereoisomerically pure compound of RS/SR configuration characterized in that said reduction is carried out by the use of (+)-B-chlorodiisopinocampheylborane or (−)-B-chlorodiisopinocampheylborane. The compounds of formula (II) are useful as intermediates for the preparation of Nebivolol. | 01-27-2011 |
Franco Massaccesi, Grancona IT
Patent application number | Description | Published |
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20090018089 | CRYSTALLINE FORMS OF MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY - the present invention relates to macrolide compounds endowed with antiinflammatory activity and more particularly relates to new stable crystalline forms of a macrolide derivative with antiinflammatory activity, processes for the preparation of such forms, pharmaceutical compositions containing them as active ingredient and the use of said crystalline forms for the treatment of inflammatory diseases. | 01-15-2009 |
20100076204 | PROCESS FOR THE PREPARATION OF LEVETIRACETAM - The present invention relates to a process for the preparation of levetiracetam and, more particularly, to an improved process for the preparation of levetiracetam characterized by a crystallization-induced dynamic resolution of a diastereoisomeric mixture of an (±)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide derivative. | 03-25-2010 |
Franco Massaccesi, Lonigo IT
Patent application number | Description | Published |
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20100056813 | PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for preparing nebivolol and, more particularly, to a process for preparing d-nebivolol and its enantiomer l-nebivolol or acid addition salts thereof starting from commercially available or easily obtainable 2,2-dimethyl-1,3 dioxolane-4-carbaldehyde and a vinyl Grignard reagent. | 03-04-2010 |
20110201831 | PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for preparing nebivolol and, more particularly, to a process for preparing d-nebivolol and its enantiomer l-nebivolol or acid addition salts thereof starting from commercially available or easily obtainable 2,2-dimethyl-1,3 dioxolane-4-carbaldehyde and a vinyl Grignard reagent. | 08-18-2011 |
Gianluca Massaccesi, Casalecchio Di Reno IT
Patent application number | Description | Published |
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20090080323 | Device and Method for Obtaining a Substrate Structured on Micrometric or Nanometric Scale - A method for providing a locally rough surface which is spatially structured on micrometric and/or nanometric scale and is formed by a substrate, so as to obtain a product. The method comprises the steps of flattening and/or smoothing the rough substrate in preset regions. | 03-26-2009 |
20100098913 | DEVICE AND METHOD FOR PROTECTION AND ACTIVATION OF SENSORS - A device and a corresponding method which allows to protect, preserve and activate (making it sensitive to external agents) a sensitive element, which changes its morphology and/or produces phase segregations following exposure to external agents. | 04-22-2010 |