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Masachika
Masachika Azuma, Nagoya-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20090203538 | Method of classifying antibody, method of identifying antigen, method of obtaining antibody or antibody set, method of constructing antibody panel and antibody or antibody set and use of the same - It is intended to provide a method whereby a plural number of antibodies against cell surface antigens are quickly classified and to provide a method whereby antigens of the thus classified antibodies are quickly identified. Further, it is intended to provide a method of promoting the utilization of the useful data obtained by the above methods. Furthermore, it is intended to provide an antibody which is effective in treating or diagnosing cancer. Namely, a method of classifying antibodies which comprises: (1) the step of preparing a plural number of antibodies respectively recognizing cell surface antigens; (2) the step of bringing each of these antibodies into contact with a cell of the same species; (3) the step of analyzing each of the cells having been treated in the step (2) by flow cytometry and thus obtaining data indicating the reactivity of each antibody with its cell surface antigen; and (4) the step of comparing the thus obtained data and classifying the individual antibodies depending on the similarity. A method of identifying antigens which further comprises: (5) the step of selecting one to several antibodies from each antibody group formed in the step (4) and identifying antigens thereof; and (6) on the assumption that antigens of the antibodies belonging to a single antibody group are the same or highly related to one another, making relations between the antigens having been identified in the step (5) and the antibody groups to thereby identify the antigens. An antibody against HER1, an antibody against HER2, an antibody against CD46, an antibody against ITGA3, an antibody against ICAM1, an antibody against ALCAM, an antibody against CD147, an antibody against C1qR, an antibody against CD44, an antibody against CD73, an antibody against EpCAM and an antibody against HGFR, each obtained by using the above methods. | 08-13-2009 |
| 20110014211 | COMPOSITION FOR NEUTRALIZING BOTULINUS TOXIN TYPE-A, AND HUMAN ANTI-BOTULINUS TOXIN TYPE-A ANTIBODY - Provided herein is a means which is effective for botulism diseases and the prevention of the botulism diseases. Specifically provided is a plurality of human anti-botulinum toxin type-A antibodies having different epitopes from one another. Also specifically provided is a composition for neutralizing botulinum toxin type-A, which comprises a combination of two or more of the antibodies and which has a high neutralizing activity. | 01-20-2011 |
Masachika Azuma, Aichi JP
| Patent application number | Description | Published |
|---|---|---|
| 20090053243 | Anti-IgSF4 Antibody and Utilization of the Same - It is intended to clarify a molecule which is available as a target in treating or diagnosing cancer and utilize the molecule in the medical field or the research field. By treating IgSF4, which has been identified as a molecule specifically expressed in lung cancer cells, with an antibody, and ADCC activity is exerted. Based on this finding, an anti-IgSF4 antibody is provided as a means efficacious in treating cancer, etc. | 02-26-2009 |
Masachika Kamiya, Toyota-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20110054735 | DOOR COURTESY SWITCH ABNORMALITY DETECTION APPARATUS AND METHOD - A door courtesy switch abnormality detection apparatus used in an on-vehicle system in which a door unlocked status is formed based on a wireless signal transmitted from an electronic key is disclosed. The apparatus is configured to generate information representing an abnormality in the door courtesy switch, if the electronic key in a cabin of a vehicle is detected by a antenna having the detection area thereof within the cabin of the vehicle in a situation where an ON/OFF signal of the door courtesy switch is not inverted after the door unlock operation is detected. | 03-03-2011 |
Masachika Watanabe, Shinjuku-Ku JP
| Patent application number | Description | Published |
|---|---|---|
| 20100073745 | HOLOGRAM FABRICATION PROCESS, AND HOLOGRAM FABRICATED BY THAT PROCESS - The invention provides a hologram fabrication process, characterized by comprising steps of fabricating a computer-generated hologram (CGH) having amplitude information and phase information recorded by computer operation on a given recording surface, irradiating the computer-generated hologram (CGH) with the first reconstructing illumination light ( | 03-25-2010 |
Masachika Watanabe, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20090104539 | FABRICATION PROCESS FOR CHOLESTERIC LIQUID CRYSTAL MEDIA HAVING A VOLUME HOLOGRAM - A volume hologram layer ( | 04-23-2009 |
| 20090195846 | HOLOGRAM AND ITS HOLOGRAPHIC PROCESS - The invention relates to a security-conscious hologram which can apply a sufficient three-dimensional appearance to a reconstructed image in both its vertical and horizontal directions, and which is difficult to illegally copy and easily told from any illegal copy forged from it, and a holographic process of recording it The hologram H | 08-06-2009 |
| 20090197187 | HOLOGRAM FABRICATION PROCESS AND FABRICATED HOLOGRAM - The invention provides a hologram in which a visually unidentifiable microtext or other micropattern of the order of 10 μm is recorded, and a process for the fabrication of the same. A volume hologram recording material | 08-06-2009 |
| 20090219592 | FABRICATION PROCESS FOR CHOLESTERIC LIQUID CRYSTAL MEDIA HAVING A VOLUME HOLOGRAM - The invention provides a process capable of fabricating a cholesteric liquid crystal medium having a volume hologram with efficiency yet without recourse to complicated steps such as an alignment step. This is achievable as follows. A volume hologram layer is formed on a substrate, and a cholesteric liquid crystal layer is then formed on another substrate comprising a center substrate film that is subjected to bondable treatment. The volume hologram layer is applied to the center substrate film that is subjected to bondable treatment, and placed in a state where the volume hologram layer and cholesteric liquid crystal layer are laminated together via the substrate. The substrate is peeled off the volume hologram layer, and an adhesive layer is formed on the surface of the volume hologram layer off which the substrate is peeled off, followed by the provision of the substrate on the adhesive layer. Finally, the multilayer structure is shaped into a label form of cholesteric liquid crystal medium having a volume hologram layer. | 09-03-2009 |
Masachika Watanabe, Tokyo-To JP
| Patent application number | Description | Published |
|---|---|---|
| 20090059158 | OPTICAL DIFFUSION DEVICE, PROJECTION SCREEN, DESIGN MEMBER AND SECURITY MEDIUM - The present invention provides an optical diffusion device, which can exhibit discontinuously different optical properties only in desired regions without creating any difference in grades and/or breaks, facilitate control of the optical diffusion properties, and prevent the occurrence of the stray light, as well as provides a projection screen and a design member, both using the optical diffusion device. An exemplary optical diffusion device according to this invention includes a base, and a cholesteric liquid crystal polymer layer provided on the base and composed of a plurality of diffusion regions arranged on a plane. A diffusion angle of one of the diffusion regions (e.g., first diffusion regions) of the cholesteric liquid crystal polymer layer is different from a diffusion angle of another of the diffusion regions (e.g., second diffusion regions). | 03-05-2009 |