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Mary E.

Mary E. Alwin, Crawfordsville, IN US

Patent application numberDescriptionPublished
20080264525HIGH COPPER LOW ALLOY STEEL SHEET - A high copper low alloy steel sheet less than 5 mm is made by preparing a molten melt producing an as-cast low alloy steel comprising by weight, 0.02 % to 0.3% carbon, 0.10% to 1.5% manganese, 0.01% to 0.5% silicon, greater than 0.01 % and less than or equal 0.15% phosphorus, less than 0.05% aluminum, more than 0.20% copper, less than 0.03 % tin, less than 0.10 % nickel, total oxygen level at least 70 ppm and usually less than 250 ppm, free oxygen content 20 to 70 ppm, the remainder iron and impurities, solidifying the melt into sheet less than 10 mm thickness in a non-oxidizing atmosphere to below 1080° C. Copper content may be between 0.2% and 2.0% by weight. The steel may have a corrosion index (I) of at least 6.0 in accordance with ASTM G101 where: I=26.01 (% Cu)+3.88 (% Ni)+1.20 (% Cr)+1.49 (% Si)+17.28 (% P)−7.29 (% Cu)(% Ni)−9.10 (% Ni)(% P)−33.39 (% Cu)10-30-2008

Mary E. Alwin-Becker, Crawfordsville, IN US

Patent application numberDescriptionPublished
20100215981HOT ROLLED THIN CAST STRIP PRODUCT AND METHOD FOR MAKING THE SAME - A hot rolled steel strip made by the steps including assembling a twin roll caster, forming a casting pool of molten steel having a free oxygen content between 20 and 75 ppm and having a composition such that the cast strip comprises by weight, less than 0.25% carbon, between 0.9 and 2.0% manganese, between 0.05 and 0.50% silicon, greater than 0.01% and less than or equal to 0.15% phosphorus, and less than 0.01% aluminum, counter rotating the casting rolls forming the steel strip, hot rolling the strip such that mechanical properties at 10% and 35% reduction are within 10% for yield strength, tensile strength and total elongation, and coiling the strip at a temperature between 300 and 700° C. to provide a majority of the microstructure comprising bainite and acicular ferrite. Alternatively, the steel may have between 0.20 and 0.60% copper and manganese as low as 0.08%.08-26-2010

Mary E. Bellizzi, North Chicago, IL US

Patent application numberDescriptionPublished
20100317568Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.12-16-2010
20110092415Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.04-21-2011
20110207699Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.08-25-2011

Mary E. Bellizzi, Lake Forest, IL US

Patent application numberDescriptionPublished
20120004196Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.01-05-2012

Mary E. Birli, Garfield Heights, OH US

Patent application numberDescriptionPublished
20100155545MODULAR ROOFTOP PIPE SUPPORT - An extruded or molded elastomeric (e.g., rubber) or polymeric multi-piece (e.g., two-piece) modular pipe support system utilizes a wide base with protrusions and/or recesses, and a separate top with recesses and/or protrusions that engage the protrusions and/or recesses of the top. The tops are configured to securely capture a pipe/conduit without any additional parts, straps, etc. The top may have one or more pipe-receiving recesses for receiving the pipes (conduits).06-24-2010

Mary E. Brunkow, Seattle, WA US

Patent application numberDescriptionPublished
20080234219Compositions and Methods for Increasing Bone Mineralization - A novel class or family of TGF-β binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules.09-25-2008
20090169543Method for regulating immune function in primates using the Foxp3 protein - Isolated nucleic acid molecules are provided which encode Fkh07-02-2009
20100003755Methods for identifying genomic deletions - The genomic locus responsible for Van Buchem's disease is narrowed to an approximately 92 kb region of human chromosome 17 at 17q21. Individuals afflicted with or carriers of Van Buchem's disease exhibit a 52 kb deletion within this 92 kb region. Methods are provided that permit the differentiation between individuals homozygous for and therefore afflicted with Van Buchem's disease, individuals heterozygous for and therefore carriers of Van Buchem's disease, and individuals who are normal with respect to Van Buchem's disease. Also provided are general methodologies for the detection of a wide variety of large genomic deletions.01-07-2010
20110070588Methods for Identifying Genomic Deletions - The genomic locus responsible for Van Buchem's disease is narrowed to an approximately 92 kb region of human chromosome 17 at 17q21. Individuals afflicted with or carriers of Van Buchem's disease exhibit a 52 kb deletion within this 92 kb region. Methods are provided that permit the differentiation between individuals homozygous for and therefore afflicted with Van Buchem's disease, individuals heterozygous for and therefore carriers of Van Buchem's disease, and individuals who are normal with respect to Van Buchem's disease. Also provided are general methodologies for the detection of a wide variety of large genomic deletions.03-24-2011
20110150866Compositions and Methods for Increasing Bone Mineralization - A novel class or family of TGF-β binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules.06-23-2011

Patent applications by Mary E. Brunkow, Seattle, WA US

Mary E. Caryk, Batavia, NY US

Patent application numberDescriptionPublished
20090239451Automatic Shift Dual-Action Tool - Tools providing automatic, smooth shifting between random orbital and rotary motion by simply increasing or decreasing force applied are taught. Exemplar is a finishing tool switchable between grinding rotary action and random orbital sanding action without powering down and without any mechanical manipulation, made possible by having a clutch mechanism affixed directly to the spindle assembly, which also eliminates the need to dissemble the tool in order to change a backup pad, saving time and money. Direct relationship between the clutch and spindle eliminates need for a specialty pad allowing for use of a variety of backup pads, reducing the cost of replacement backup pads and increasing the functionality of the dual-function tool. An additional feature is that the drive head surface is circular and large enough to encompass the device's circular clutch plate, which means that the available friction surface area of the clutch plate is efficiently utilized.09-24-2009

Mary E. Couwenhoven, Fairport, NY US

Patent application numberDescriptionPublished
20080279440METHOD FOR RENDERING DIGITAL RADIOGRAPHIC IMAGES FOR DISPLAY BASED ON INDEPENDENT CONTROL OF FUNDAMENTAL IMAGE QUALITY PARAMETERS - A system for enhancing a digital image. The system includes: means for providing a digital image; means for decomposing the provided digital image into a multi-frequency band representation of four frequency bands as follows: a lowest frequency band image which represents large-sized features in the digital image; a low-to-mid frequency band image which represents mid-sized features of the digital image; a mid-to-high frequency band image which represents the small-sized features in the digital image; and a highest frequency band which represents very fine detail in the digital image; means for manipulating said low-to-mid frequency band image to produce a contrast effect without affecting the overall dynamic range of said digital image; means for multiplying each of said high-frequency band images with a gain factor; means for summing together said unmodified low frequency band image and said modified high-frequency band images to produce a reconstructed digital image; and means for mapping said reconstructed digital image through a tone-scale look-up table to map said reconstructed digital image to optical densities.11-13-2008
20100086182DIAGNOSTIC IMAGE PROCESSING WITH AUTOMATIC SELF IMAGE QUALITY VALIDATION - A method for medical diagnostic image processing obtains digital image data for a diagnostic image and extracts one or more image features from the image data, obtaining one or more image properties from the one or more extracted features. An image quality aim is obtained for rendered image appearance according to one or more stored viewer preferences. Rendering parameters are generated according to the obtained image quality aim and the one or more obtained image properties. The image is rendered according to the generated rendering parameters and the rendering validated against the selected image quality aim.04-08-2010

Patent applications by Mary E. Couwenhoven, Fairport, NY US

Mary E. Ewasyshyn, Thornhill CA

Patent application numberDescriptionPublished
20080311624Chimeric immunogens - Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.12-18-2008
20080312412Chimeric immunogens - Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.12-18-2008

Mary E. Koban, Chadds Ford, PA US

Patent application numberDescriptionPublished
20090120619METHOD FOR EXCHANGING HEAT IN VAPOR COMPRESSION HEAT TRANSFER SYSTEMS - The present disclosure relates to a method for exchanging heat in a vapor compression heat transfer system. In particular, it relates to use of an intermediate heat exchanger to improve performance of a vapor compression heat transfer system utilizing a working fluid comprising at least one fluoroolefin. In addition, the present disclosure relates to a vapor compression heat transfer system comprising an intermediate heat exchanger in combination with a dual-row evaporator or a dual-row condenser, or both.05-14-2009
20110290447METHOD FOR EXCHANGING HEAT IN VAPOR COMPRESSION HEAT TRANSFER SYSTEMS - A multi-step method is disclosed for exchanging heat in a vapor compression heat transfer system having a working fluid circulating therethrough. The method includes the step of circulating a working fluid comprising a fluoroolefin to an inlet of a first tube of an internal heat exchanger, through the internal heat exchanger and to an outlet thereof. Also disclosed are vapor compression heat transfer systems for exchanging heat. The systems include an evaporator, a compressor, a dual-row condenser and an intermediate heat exchanger having a first tube and a second tube. A disclosed system involves a dual-row condenser connected to the first and second intermediate heat exchanger tubes. Another disclosed system involves a dual-row evaporator connected to the first and second intermediate heat exchanger tubes.12-01-2011

Mary E. Mizialko, Naperville, IL US

Patent application numberDescriptionPublished
20100142956Method and Apparatus for Reshaping a Channel Signal - Higher rate channels (e.g., 40 Giga bits or greater) have large bandwidths and are susceptible to inter-channel crosstalk. Optical tunable filters may be used to overcome crosstalk. Tunable filters do not maintain their central wavelength over a long duration or a wide temperature range. An example embodiment of the present invention relates to shaping a channel signal within a dense wavelength division multiplexing signal and may employ a tunable filter and input and output optical power detectors to measure a modulated source channel signal at an input of the tunable filter and a filtered modulated source channel signal at an output of the tunable filter. A controller is configured to adjust a center wavelength of the tunable filter as a function of a difference between measurements of optical power by the optical power detectors. Adjusting the center wavelength shapes the channel signal and overcomes undesired effects for higher rate channels.06-10-2010

Mary E. Moore, Barrington, NH US

Patent application numberDescriptionPublished
20080236943SOUND PROOFING SYSTEM AND METHOD - A low-cost and easy to manufacture static structure and method for soundproofing walls, floors, and/or ceilings of rooms in new and/or existing construction utilizes an asphalt based flexible membrane as one or more sound absorbing layers which may be applied to an existing wall panel or first applied to one or more unmounted wall panels to form a laminated structure which is then affixed to the walls, floor or ceiling to be soundproofed. The wall panel is preferably gypsum wallboard. Each sound absorbing layer, in addition to soundproofing, may also serve to prevent or at least reduce air or water infiltration to and from the room.10-02-2008
20090288360SOUND PROOFING SYSTEM AND METHOD - A low-cost and easy to manufacture static structure and method for soundproofing walls, floors, and/or ceilings of rooms in new and/or existing construction utilizes an asphalt based flexible membrane as one or more sound absorbing layers which may be applied to an existing wall panel or first applied to one or more unmounted wall panels to form a laminated structure which is then affixed to the walls, floor or ceiling to be soundproofed. The wall panel is preferably gypsum wallboard. Each sound absorbing layer, in addition to soundproofing, may also serve to prevent or at least reduce air or water infiltration to and from the room.11-26-2009

Mary E. Mootoo, Cincinnati, OH US

Patent application numberDescriptionPublished
20110251612ELECTROSURGICAL CUTTING AND SEALING INSTRUMENTS WITH CAM-ACTUATED JAWS - Various embodiments are directed to a surgical instrument comprising, a shaft, and an end effector. The shaft may be coupled to the handle and may extend distally along a longitudinal axis. The end effector may be positioned at a distal end of the shaft and may comprise first and second jaw members and a reciprocating member. The first and second jaw members may define first and second longitudinal slots. One or both of the jaw members may be pivotable relative to the other about a pivot point. The reciprocating member may be translatable distally and proximally parallel to the longitudinal axis and through the first and second longitudinal slots. A distal portion of the reciprocating member may define a blade. The instrument may comprise an overtube translatable distally to exert a force on a portions of the first and second jaw members tending to close the first and second jaw members.10-13-2011
20110306963ELECTROSURGICAL INSTRUMENT EMPLOYING AN ELECTRODE - An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. In various embodiments, the first and second jaws can comprise one or more electrodes configured to apply a voltage across the tissue, wherein at least one of the electrodes can comprise a conductive material positioned within a non-conductive, or high-resistance, material. In use, current flowing through the conductive material can heat the conductive material and cause it to evaporate and leave behind the non-conductive material. In such circumstances, the current flowing through the electrode may cease or may be substantially reduced.12-15-2011
20110306965ELECTROSURGICAL INSTRUMENT EMPLOYING MULTIPLE POSITIVE TEMPERATURE COEFFICIENT ELECTRODES - An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed in order to capture tissue therebetween. In various embodiments, the first and second jaws can comprise one or more electrodes configured to apply a voltage across the tissue, wherein one or both of the first and second jaws can include a plurality of electrodes each comprised of a positive temperature coefficient material having a different switching temperature. The electrical resistances of the electrodes can increase significantly once the temperature of the electrodes exceed their switching temperatures and, owing to the increased electrical resistance, the flow of current through the electrodes can be reduced and/or prevented. In various circumstances, the different switching temperatures of the electrodes can allow some of the electrodes to switch off before the other electrodes.12-15-2011
20110306966ELECTROSURGICAL INSTRUMENT EMPLOYING A PLURALITY OF ELECTRODES - An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed to capture tissue therebetween. The second jaw can comprise a first electrode and a second electrode while the first jaw can comprise an opposing electrode positioned opposite the first electrode and the second electrode when the jaws are in their closed position. The first and second electrodes can be independently and/or sequentially operated in order to conduct current between the first and second electrodes and opposing electrode in order to draw the tissue positioned between the first and second jaws toward the center of the first and second jaws and weld the tissue. In various other embodiments, other firing sequences of the electrodes are contemplated. During and/or after such tissue welding processes, a cutting member can be advanced to cut the tissue.12-15-2011
20110306968HEAT MANAGEMENT CONFIGURATIONS FOR CONTROLLING HEAT DISSIPATION FROM ELECTROSURGICAL INSTRUMENTS - In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed.12-15-2011

Mary E. Rabaglia, Lodi, WI US

Patent application numberDescriptionPublished
20110071222POTENTIATORS OF INSULIN SECRETION - The present invention relates to a recognition that an analog of αKG can increase glucose-induced insulin secretion in vitro and in vivo in animals, particularly in mammals, and more particularly in humans and in rodents. By employing the methods of the invention, insulin secretion can be increased.03-24-2011

Mary E. Senkus, Hudson, WI US

Patent application numberDescriptionPublished
20090215345PARTICLE-CONTAINING FIBROUS WEB - A porous sheet article comprising a self-supporting nonwoven web of polymeric fibers and at least 80 weight percent sorbent particles enmeshed in the web, the fibers having sufficiently greater elasticity or sufficiently greater crystallization shrinkage than similar caliper polypropylene fibers and the sorbent particles being sufficiently evenly distributed in the web so that the web has an Adsorption Factor A of at least 1.6×1008-27-2009

Mary E. Suddendorf, Waconia, MN US

Patent application numberDescriptionPublished
20090216861Integrated Software Network Agent - A model for the next generation of software network agents for downloadable software is provided. The software network agent delivers a streamlined user experience that presents the user with options to try or buy. The agent may be co-branded for merchant and affiliate marketing. The agent may be integrated with a number of services, such as ecommerce systems, affiliate marketing network systems, site optimization, web analytics and email marketing systems that enable a merchant to enhance the user experience and improve marketing. A user's actions may be tracked in order to provide OEMs and retailers payout on purchase referrals to the merchant's online store. Code changes and bug fixes can be made at the server and in a timely manner with minimal impact to the various systems supporting the software activation user experience.08-27-2009

Mary E. Tabacco, Brighton, MA US

Patent application numberDescriptionPublished
20090144022Mixed statistical and numerical model for sensor array detection and classification - A method and system for detecting and classifying biosensor and chemical sensor data includes processing data fetched from an array of sensors. A statistical analysis of the processed data is performed, to obtain statistically analyzed sensor data. A determination is made, based on the statistically analyzed sensor data, whether or not there a response signal has been generated from the array of sensors. If a response signal is determined to have been generated, a numerical pattern recognition is performed on the data collected from the array of sensors, in order to categorize the data06-04-2009

Mary E. Vaman Rao, Hopkinton, MA US

Patent application numberDescriptionPublished
20110213021COMPOSITIONS AND METHODS FOR TREATING NOS-ASSOCIATED DISEASES - The disclosures herein provide lipoic acid salts, as well as polymorphs, solvates, and hydrates thereof. These salts may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, transdermal administration, or injection. Such compositions may be used to treat NOS-associated diseases such as inflammatory diseases, metabolic diseases and neurodegenerative diseases.09-01-2011
20110262976PRODUCTION OF R-a-LIPOIC ACID BY FERMENTATION USING GENETICALLY ENGINEERED MICROORGANISMS - This application provides systems and methods for the production of R-α-lipoic acid. Lipoic acid synthesis genes may be expressed in an acid-tolerant microorganism, such as 10-27-2011