Marlis
Marlis Gonzalez-Fernandez, Catonsville, MD US
Patent application number | Description | Published |
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20120136284 | ACTIVE HAND-EXTENSION/FLEXION DEVICE - A hand movement device comprises a glove for positioning about a hand of a user, a first anchor element adapted to be positioned about a base surface of glove, a second anchor element adapted to be positioned at a tip of a finger portion of the glove, an active spring member positioned between the first and second anchor elements, said active spring member being fixedly secured to said first anchor element and moveable through said second anchor element to thereby allow said spring member to bend about a joint of the finger when said finger is flexed, an activating element positioned adjacent the active spring member to heat or cool said active spring member thereby causing the spring member to bend or straighten, and an intermediary support device for housing said spring element and for connecting the first anchor element to said second anchor element. | 05-31-2012 |
Marlis Huebner, Cambridge GB
Patent application number | Description | Published |
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20120094858 | BIOMARKERS - The invention relates to a method of diagnosing or monitoring bipolar disorders, in particular bipolar I and bipolar II disorders, such as manic psychosis. | 04-19-2012 |
20130059750 | BIOMARKERS - The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder. | 03-07-2013 |
20130078645 | BIOMARKERS - The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder. The biomarkers used are selected from cyclophilin A, cytosalic non-specific dipepditase, Caoctosin-like protein, Glucose-6-phosphate isomerase, uncharacterized protein KIAA0423, myosin 14, myosin 15, nicotinamide phosphoribosyltransferase, pyruvate kinase isozyme R/L, phosphoglyterate mutase 4. | 03-28-2013 |
Marlis Zeiler, Neibkirchen AT
Patent application number | Description | Published |
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20140072991 | QUANTITATIVE STANDARD FOR MASS SPECTROMETRY OF PROTEINS - The present invention provides a method of determining the absolute amount of a target polypeptide in a sample, said method comprising the following steps: (a) adding (aa) a fusion polypeptide to said sample, said fusion polypeptide comprising (i) at least one tag sequence and (ii) a subsequence of the target polypeptide; and (ab) a known absolute amount of a tag polypeptide comprising or consisting of said tag sequence according to (aa) to said sample, wherein said fusion polypeptide on the one hand is mass-altered as compared to said target polypeptide and said tag polypeptide on the other hand, for example, said fusion polypeptide on the one hand and said target polypeptide and said tag polypeptide on the other hand are differently isotope labeled; (b) performing proteolytic digestion of the mixture obtained in step (a); (c) subjecting the result of proteolytic digestion of step (b), optionally after chromatography, to mass spectrometric analysis; and (d) determining the absolute amount of said target polypeptide from (i) the peak intensities in the mass spectrum acquired in step (c) of said fusion polypeptide, said tag polypeptide and said target polypeptide and (ii) said known absolute amount of said tag polypeptide. | 03-13-2014 |