Mark L. Nelson
Mark L. Nelson, Wellesley, MA US
Patent application number | Description | Published |
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20080306032 | 7-Phenyl-Substituted Tetracycline Compounds - 7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. 7-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described. | 12-11-2008 |
20090258842 | 7-Phenyl-Substituted Tetracycline Compounds - 7-phenyl-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. | 10-15-2009 |
20090306022 | 7-SUBSTITUTED TETRACYCLINE COMPOUNDS - The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression. | 12-10-2009 |
20110086821 | Tetracycline Compounds for Treatment of Cryptosporidium Parvum Related Disorders - Methods and compositions for treating | 04-14-2011 |
Mark L. Nelson, Charleston, WV US
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20100144967 | METHODS OF CONTROLLING PROPERTIES IN MULTIMODAL SYSTEMS - The invention is directed to a polymerization system and method of controlling resin properties during the production of bimodal and multimodal polymer compositions using at least one manipulated variable to minimize dynamic deviations from polymer characteristics. In particular embodiments, the method of control includes determining a property of the resin based on a current and/or previous values or estimates or process variables or polymer characteristics. In this manner the control actions serve to reduce process upsets or facilitate in transitioning to a new product or grade to reduce the amount of off-grade resin material produced during transition or during steady state manufacture. | 06-10-2010 |
20100209307 | METHOD FOR IMPROVING THE PREDICTION OF POLYMER PROPERTIES AND A SYSTEM HAVING IMPROVED POLYMER PROPERTY PREDICTION CAPABILITIES - The instant invention is a method for improving the prediction of polymer properties and a system having improved polymer property prediction capabilities. The method for improving the prediction of polymer properties according to instant invention comprises the following steps of: (1) providing a polymer; (2) providing a prediction model; (3) utilizing said prediction model to define an average polymer property prediction value; (4) determining a feasible range; (5) measuring one or more properties of said polymer; (6) determining whether said one or measured polymer properties are within said feasible range: (7) validating said one or more measured polymer properties if said one or more measured polymer properties fall within the feasible range or invalidating said one or more measured polymer properties if said one or more measured polymer properties fall outside of the feasible range; (8) optionally updating said prediction model; (9) repeating said previous steps at least one or more times; and (10) thereby improving the prediction of polymer properties. The polymerization system having improved polymer property prediction capabilities according to instant invention comprises at least one polymerization reactor; an automated prediction model; means for measuring one or more polymer properties; means for detecting one or more erroneous measured polymer properties; and means for updating said automated predication model. | 08-19-2010 |
Mark L. Nelson, Palouse, WA US
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20100197029 | DIRECT METHOD AND REAGENT KITS FOR FATTY ACID ESTER SYNTHESIS - Provided are efficient, cost-effective and water tolerant methods (e.g., single-vial methods) for preparing fatty acid esters from organic matter, comprising: obtaining organic matter comprising at least one fat substituent, contacting the organic matter in a reaction mixture with a basic solution under conditions suitable to provide for hydrolytic release of monomeric fatty acids from the at least one fat substituent to provide a base-treated reaction mixture, and esterifying the monomeric fatty acids of the base-treated reaction mixture by acidification of the reaction mixture and treating in the presence of an organic alcohol to provide fatty acid esters. The methods optionally further comprise, prior to esterifying, neutralizing the base-treated reaction mixture to provide for neutralized fatty acids, separating the neutralized fatty acids from the neutralized reaction mixture, and dissolving the separated fatty acids in the esterification reaction mixture. Also provided are related methods and kits for fat analysis. | 08-05-2010 |
Mark L. Nelson, Denver, CO US
Patent application number | Description | Published |
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20090158642 | MOTOR FUEL ADDITIVE COMPOSITION - Disclosed is a MMT containing motor fuel additive composition which synergistically interacts with the MMT additive to reduce both fuel intake system deposit formation and combustion chamber deposit formation, thereby reducing engine ORI and maintaining desired engine performance. | 06-25-2009 |
20090158643 | MOTOR FUEL ADDITIVE COMPOSITION - Disclosed is a leaded motor fuel additive composition which synergistically interacts with the alkyl lead additive to reduce both fuel intake system deposit formation and combustion chamber deposit formation, thereby reducing engine ORI and maintaining desired engine performance. | 06-25-2009 |