Patent application number | Description | Published |
20090124660 | Piperidine Compounds Useful as Malonyl-CoA Decarboxylase Inhibitors - The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity. | 05-14-2009 |
20090143352 | PYRROLO-PYRIDINE KINASE MODULATIORS - The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity. | 06-04-2009 |
20100036118 | Fused Ring Heterocycle Kinase Modulators - The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity. | 02-11-2010 |
20100305128 | Pyrimidinyl-Thiophene Kinase Modulators - The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity. | 12-02-2010 |
20110028514 | Azoles as Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators - The present invention relates to methods of treatment of certain metabolic diseases, and to novel compounds and their prodrugs, and/or pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds useful in treating such diseases. In particular, this invention relates to the use of novel compounds and compositions for treatment of cardiovascular diseases, diabetes, cancers, acidosis, and obesity through the inhibition of malonyl-CoA decarboxylase (MCD). These compounds have the formulae (I) and (II), wherein Y, C, R | 02-03-2011 |
20110065691 | THERAPEUTIC PIPERAZINES - The invention includes a compound of formula I: | 03-17-2011 |
20140275531 | SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS PDE4 INHIBITORS - The invention provides a chemical entity of Formula (I) | 09-18-2014 |
20140315913 | SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS PDE4 INHIBITORS - The invention provides a chemical entity of Formula (I) | 10-23-2014 |
20150087645 | THERAPEUTIC PIPERAZINES - The invention includes a compound of formula I: | 03-26-2015 |