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Marisol
Marisol Corral-Debrinski, Montreuil FR
| Patent application number | Description | Published |
|---|---|---|
| 20090306188 | IMPORTATION OF MITOCHONDRIAL PROTEIN BY AN ENHANCED ALLOTOPIC APPROACH - The inventors demonstrate that mRNA sorting to the mitochondrial surface is an efficient way to proceed to such an allotopic expression, and that this mRNA sorting can be controlled by selecting appropriate mitochondrion-targeting sequence (MTS) and appropriate 3′UTR sequences. The CDS sequence which codes for the protein to be delivered into the mitochondrion is guided by these appropriate MTS and 3′UTR sequences from the nuclear compartment to the mitochondrion-bound polysomes (where the CDS is translated), and aids in an efficient translocation of a mature functional protein into the mitochondria. Appropriate MTS and 3′UTR sequences correspond to those of nuclearly-transcribed mitochondrially-targeted mRNAs. The inventors demonstrate that, to obtain a stable therapeutically-effective importation, both an appropriate MTS and an appropriate 3′UTR should preferably be used. | 12-10-2009 |
Marisol Ontaneda, Kirkland, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090048881 | Visualizers for Change Management System - A change management system may use a phased status indicator that may illustrate several phases of a change request and a current status for each phase of a change management lifecycle. Additionally, a group of change requests may be displayed in a linked manner showing various relationships between change requests. The status indicator and linked display may be used together or separately to illustrate the status of various change requests and within interactive displays of change request data. | 02-19-2009 |
Marisol Ontaneda, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20080244258 | Instrumenting Configuration and System Settings - Described are systems and methods for instrumenting configuration and system settings based on targeting configuration settings at dynamically populated groups, groups with varied membership, and objects defined in a class. The systems and methods provide for attributing a configuration setting or policy to one or more objects and then targeting the object at one or more scope. | 10-02-2008 |
| 20080301803 | Tailored System Management Interface - Processes and techniques for tailoring operations management in a system are described. The processes and techniques allow a user to customize operations management based on the user's function within a system and the particular tasks that the user wishes to accomplish. Simplified user interfaces can be created by scoping the interfaces based on user profiles, preferences and system components. | 12-04-2008 |
| 20090006954 | UNIFIED USER EXPERIENCE USING CONTEXTUAL INFORMATION, DATA ATTRIBUTES AND DATA MODELS - Various implementations are described herein for providing unified user experiences using data attributes and data models. By referencing structural information of data attributes included in data models, users are able to interact with and/or view related data stored in different databases. Contextual information for the different databases, data attributes, and data models provide a seamless unified user experience when running reports, scripts, web controls and so forth associated with the related data. | 01-01-2009 |
Marisol Pages, Santo Domingo DO
| Patent application number | Description | Published |
|---|---|---|
| 20090233273 | Transgenic aloe plants for production of proteins and related methods - The present inventions provide transgenic aloe plants and recombinant constructs for transforming aloe plants, aspects of which, may be applied to other monocots. The recombinant constructs may include one or more DNA sequences encoding mammalian proteins and at least one promoter capable of directing the expression of recombinant proteins in an aloe plant. The present inventions also provide methods for constructing and reproducing a transgenic aloe plant. The present inventions include methods for transfection of an aloe plant with several genes of interest simultaneously. The aloe plant production methods of the inventions may provide the potential to inexpensively and more safely mass-produce some biologically active compounds including biopharmaceuticals for disease therapy, diagnosis and prevention, and is more accessible to the less affluent countries. The aloe plant production methods may also produce proteins for cosmetics. | 09-17-2009 |