Patent application number | Description | Published |
20130087020 | CONTINUOUS FLOW SYNTHESIS OF NANOMATERIALS USING IONIC LIQUIDS IN MICROFLUIDIC REACTORS - A method for manufacturing metal nanoparticles includes the use of a microfluidic device. The microfluidic device has a first channel having a first inlet; a second channel having a second inlet; a third channel having a third inlet; and a main channel having a main inlet and an outlet. The first channel, second channel, and third channel all lead into the main channel. The method involves injecting a solution of a metal/ligand into the first inlet, injecting a solution of a reducing agent into the second inlet, injecting a solvent comprised of an ionic liquid into the third inlet, and injecting an inert carrier into the main inlet. The solution of the metal/ligand, the solution of the reducing agent, the solvent and the inert carrier are combined together in the main channel, and the metal/ligand and the reducing agent are reacted for a time sufficient to form a metal nanoparticle. | 04-11-2013 |
20140030165 | MICROFLUIDIC DEVICES HAVING SOLVENT-RESISTANT COATING AND METHOD OF MANUFACTURE THEREOF - A method of coating a substrate, such as a microfluidic device having an interior surface, includes heating a gas including a perfluoroacrylate, a crosslinker and an initiator at a first temperature, maintaining the substrate at a second temperature lower than the first temperature in a reaction chamber, exposing the heated gas to the substrate in the reaction chamber, and reacting the perfluoroacrylate with the initiator and crosslinker to form a polymer coating on the surface of the substrate. | 01-30-2014 |
Patent application number | Description | Published |
20100034853 | Compositions of activated botulinum toxin type B - The present invention relates to pharmaceutical compositions of activated botulinum toxin type B. In particular, the present invention relates to botulinum toxin type B pharmaceutical compositions wherein at least 75% of said botulinum toxin type B is activated—i.e., “nicked”. The invention also relates to a process of activating botulinum toxin type B wherein at least 75% of said botulinum toxin type B is nicked. The invention further relates to methods for the treatment of a variety of neuromuscular diseases, pain, inflammatory and cutaneous disorders comprising administering a pharmaceutical composition of activated botulinum toxin type B wherein at least 75% of said botulinum toxin type B is nicked. | 02-11-2010 |
20100034854 | Compositions of activated botulinum holotoxin type B (150 KD) - The present invention relates to pharmaceutical compositions of activated botulinum holotoxin type B (150 kD). In particular, the present invention relates to botulinum toxin type B pharmaceutical compositions wherein at least 75% of said botulinum toxin type B is activated (i.e., “nicked”), and wherein at least 75% said nicked botulinum toxin type B is a 150 kD holotoxin (i.e., “stripped”). The invention also relates to a process of activating and stripping botulinum toxin type B wherein at least 75% of said botulinum toxin type B is nicked, and wherein at least 75% of said nicked botulinum toxin type B is stripped. The invention further relates to methods for the treatment of a variety of neuromuscular diseases, pain, inflammatory and cutaneous disorders comprising administering a pharmaceutical composition of activated botulinum holotoxin type B (150 kD) wherein at least 75% of said botulinum toxin type B is nicked, and wherein at least 75% of said nicked botulinum toxin type B is stripped. The invention also relates to a process of stripping botulinum toxin type B, comprising the stages of: cell growth, activation, purification, and dilution; wherein at least one dissociating reagent is administered to a volume of said botulinum toxin type B; and wherein said dissociating reagent administered increases the levels of stripped botulinum toxin type B to at least 75%. | 02-11-2010 |
20100112005 | Compositions of activated botulinum toxin type B - The present invention relates to pharmaceutical compositions of activated botulinum toxin type B. In particular, the present invention relates to botulinum toxin type B pharmaceutical compositions wherein at least 90% of said botulinum toxin type B is activated—i.e., “nicked”. The invention also relates to a process of activating botulinum toxin type B wherein at least 90% of said botulinum toxin type B is nicked. The invention further relates to methods for the treatment of a variety of overactive or neuromuscular diseases, pain, inflammatory and cutaneous disorders comprising administering a pharmaceutical composition of activated botulinum toxin type B wherein at least 90% of said botulinum toxin type B is nicked. | 05-06-2010 |
20100112006 | Compositions of activated botulinum holotoxin type B (150 kD) - The present invention relates to pharmaceutical compositions of activated botulinum holotoxin type B (150 kD). In particular, the present invention relates to botulinum toxin type B pharmaceutical compositions wherein at least 90% of said botulinum toxin type B is activated (i.e., “nicked”), and wherein at least 99% said nicked botulinum toxin type B is a 150 kD holotoxin (i.e., “stripped”). The invention also relates to a process of activating and stripping botulinum toxin type B wherein at least 90% of said botulinum toxin type B is nicked, and wherein at least 99% of said nicked botulinum toxin type B is stripped. The invention further relates to methods for the treatment of a variety of neuromuscular diseases, pain, inflammatory and cutaneous disorders comprising administering a pharmaceutical composition of activated botulinum holotoxin type B (150 kD) wherein at least 90% of said botulinum toxin type B is nicked, and wherein at least 99% of said nicked botulinum toxin type B is stripped. | 05-06-2010 |
Patent application number | Description | Published |
20100221583 | HDD PATTERN IMPLANT SYSTEM - Methods and apparatus for forming substrates having magnetically patterned surfaces is provided. A magnetic layer comprising one or more materials having magnetic properties is formed on a substrate. The magnetic layer is subjected to a patterning process in which selected portions of the surface of the magnetic layer are altered such that the altered portions have different magnetic properties from the non-altered portions without changing the topography of the substrate. A protective layer and a lubricant layer are deposited over the patterned magnetic layer. The patterning is accomplished through a number of processes that expose substrates to energy of varying forms. Apparatus and methods disclosed herein enable processing of two major surfaces of a substrate simultaneously, or sequentially by flipping. In some embodiments, magnetic properties of the substrate surface may be uniformly altered by plasma exposure and then selectively restored by exposure to patterned energy. | 09-02-2010 |
20100248497 | METHODS AND APPARATUS FOR FORMING NITROGEN-CONTAINING LAYERS - Methods and apparatus for forming nitrogen-containing layers are provided herein. In some embodiments, a method includes placing a substrate having a first layer disposed thereon on a substrate support of a process chamber; heating the substrate to a temperature of at least about 250 degrees Celsius; and exposing the first layer to a radio frequency (RF) plasma formed from a process gas comprising nitrogen while maintaining the process chamber at a pressure of about 10 mTorr to about 40 mTorr to transform at least an upper portion of the first layer into a nitrogen-containing layer. In some embodiments, the process gas includes ammonia (NH | 09-30-2010 |
20100297347 | SUBSTRATE SUPPORT HAVING SIDE GAS OUTLETS AND METHODS - A substrate support for a process chamber comprises an electrostatic chuck having a receiving surface to receive the substrate and a gas distributor baseplate below the electrostatic chuck. The gas distributor baseplate comprises a circumferential sidewall having a plurality of gas outlets that are spaced apart from one another to introduce a process gas into the process chamber from around the perimeter of the substrate and in a radially outward facing direction. | 11-25-2010 |
20110127156 | CHAMBER FOR PROCESSING HARD DISK DRIVE SUBSTRATES - An apparatus for forming a magnetic pattern in a magnetic storage substrate. A chamber comprises a chamber wall that defines an internal volume, a substrate support in the internal volume of the chamber, a gas distributor disposed in a wall region of the chamber facing the substrate support, a compact energy source for ionizing a portion of the process gas provided to the chamber, and a throttle valve having a z-actuated gate member with a sealing surface for covering an outlet portal of the chamber. Ions are accelerated toward the substrate support by an electrical bias, amplifying the ion density of the process gas. A substrate disposed on the substrate support is bombarded by the ions to alter a magnetic property of the substrate surface. | 06-02-2011 |
20110163065 | SYSTEM FOR BATCH PROCESSING OF MAGNETIC MEDIA - A method and apparatus for processing multiple substrates simultaneously is provided. Each substrate may have two major active surfaces to be processed. The apparatus has a substrate handling module and a substrate processing module. The substrate handling module has a loader assembly, a flipper assembly, and a factory interface. Substrates are disposed on a substrate carrier at the loader assembly. The flipper assembly is used to flip all the substrates on a substrate carrier in the event two-sided processing is required. The factory interface positions substrate carriers holding substrates for entry into and exit from the substrate processing module. The substrate processing module comprises a load-lock, a transfer chamber, and a plurality of processing chambers, each configured to process multiple substrates disposed on a substrate carrier. | 07-07-2011 |
20110278260 | INDUCTIVE PLASMA SOURCE WITH METALLIC SHOWER HEAD USING B-FIELD CONCENTRATOR - A method and apparatus for plasma processing of substrates is provided. A processing chamber has a substrate support and a lid assembly facing the substrate support. The lid assembly has a plasma source that comprises an inductive coil disposed within a conductive plate, which may comprise nested conductive rings. The inductive coil is substantially coplanar with the conductive plate, and insulated therefrom by an insulator that fits within a channel formed in the conductive plate, or nests within the conductive rings. A field concentrator is provided around the inductive coil, and insulated therefrom by isolators. The plasma source is supported from a conductive support plate. A gas distributor supplies gas to the chamber through a central opening of the support plate and plasma source from a conduit disposed through the conductive plate. | 11-17-2011 |
20110281442 | METHODS AND APPARATUS FOR FORMING NITROGEN-CONTAINING LAYERS - Methods and apparatus for forming nitrogen-containing layers are provided herein. In some embodiments, a method of forming a nitrogen-containing layer may include placing a substrate having a first layer disposed thereon on a substrate support of a process chamber; heating the substrate to a temperature of at least about 250 degrees Celsius; and exposing the first layer to a radio frequency (RF) plasma formed from a process gas consisting essentially of ammonia (NH | 11-17-2011 |
20130001899 | ELECTROSTATIC CHUCK ASSEMBLY - Embodiments of electrostatic chucks for substrate processing are provided herein. In some embodiments, an electrostatic chuck may include a puck for supporting a substrate, the puck formed from a dielectric material and having a chucking electrode disposed within the puck proximate a support surface of the puck to electrostatically retain the substrate when disposed on the puck; a base having a ring extending from the base to support the puck; and a spacer disposed between the base and the puck to support the puck above the base such that a gap is formed between the puck and the base, wherein the spacer supports the puck proximate a peripheral edge of the puck. | 01-03-2013 |
20130288460 | PROCESS CHAMBER HAVING SEPARATE PROCESS GAS AND PURGE GAS REGIONS - Embodiments of the present invention generally relate to chambers and methods of processing substrates therein. The chambers generally include separate process gas and purge gas regions. The process gas region and purge gas region each have a respective gas inlet and gas outlet. The methods generally include positioning a substrate on a substrate support within the chamber. The plane of the substrate support defines the boundary between a process gas region and purge gas region. Purge gas is introduced into the purge gas region through at least one purge gas inlet, and removed from the purge gas region using at least one purge gas outlet. The process gas is introduced into the process gas region through at least one process gas inlet, and removed from the process gas region through at least one process gas outlet. The process gas is thermally decomposed to deposit a material on the substrate. | 10-31-2013 |
20140199785 | MULTIZONE CONTROL OF LAMPS IN A CONICAL LAMPHEAD USING PYROMETERS - A method and apparatus for processing a semiconductor substrate is described. The apparatus is a process chamber having an optically transparent upper dome and lower dome. Vacuum is maintained in the process chamber during processing. The upper dome is thermally controlled by flowing a thermal control fluid along the upper dome outside the processing region. Thermal lamps are positioned proximate the lower dome, and thermal sensors are disposed among the lamps. The lamps are powered in zones, and a controller adjusts power to the lamp zones based on data received from the thermal sensors. | 07-17-2014 |
20140273419 | MULTIZONE CONTROL OF LAMPS IN A CONICAL LAMPHEAD USING PYROMETERS - A substrate processing apparatus is provided. The substrate processing apparatus includes a vacuum chamber having a dome and a floor. A substrate support is disposed inside the vacuum chamber. A plurality of thermal lamps are arranged in a lamphead and positioned proximate the floor of the vacuum chamber. A reflector is disposed proximate the dome, where the reflector and the dome together define a thermal control space. The substrate processing apparatus further includes a plurality of power supplies coupled to the thermal lamps and a controller for adjusting the power supplies to control a temperature in the vacuum chamber. | 09-18-2014 |
Patent application number | Description | Published |
20080282250 | COMPONENT INTEGRATOR - Techniques allow for communication with and management of multiple external components. A component manager communicates with one or more component adapters. Each component adapter communicates with an external component and is able to call the methods, functions, procedures, and other operations of the external component. The component manager associates these external operations with local operations, such that an application may use local operation names to invoke the external operations. Furthermore, the component manager has component definitions and operation definitions that describe the component adapters and operations, including input and output parameters and the like. The component manager is able to receive a group of data including a local operation and a list of input and output parameters and determine from the foregoing information which external operation to call and which component adapter has access to the external operation. | 11-13-2008 |
20090132309 | GENERATION OF A THREE-DIMENSIONAL VIRTUAL REALITY ENVIRONMENT FROM A BUSINESS PROCESS MODEL - A method and computer program product for generating a three-dimensional virtual reality environment from a business process model in a computer system are provided. The method includes analyzing a business process model to identify a plurality of activities and at least one transition criterion between the plurality of activities, where the business process model is unbounded to a physical implementation. The method also includes transforming the business process model into a three-dimensional virtual reality environment with virtual physical constraints, including a plurality of virtual rooms representing the plurality of activities and one or more virtual access points to the virtual rooms representing the at least one transition criterion. The method further includes outputting the three-dimensional virtual reality environment. | 05-21-2009 |
20110320502 | CONTENT MANAGEMENT CHECKLIST OBJECT - Provided are techniques for storing at least one checklist object that includes one or more placeholders that each are associated with an object stored and managed by a content management system, receiving an indication that a new content object has been created in the content management system or that an existing content object has been modified or has reached a certain status in the content management system, in response to determining that the new content object or the change in the status fulfills one or more placeholders, marking each of the one or more placeholders as fulfilled, and indicating that the checklist object is complete when the one or more placeholders have been fulfilled. | 12-29-2011 |
20110320504 | MODELING FOR EVENT ENABLED CONTENT MANAGEMENT SYSTEMS - Provided are techniques for, in response to user input, creating a model that includes at least one icon representing a content object and an event line representing an event, wherein the event has an associated action; configuring a content management system using the model; and, in response to the event being raised, performing the action. | 12-29-2011 |
20120116953 | Generation of a Three-Dimensional Virtual Reality Environment From a Business Process Model - A method and computer program product for generating a three-dimensional virtual reality environment from a business process model in a computer system are provided. The method includes analyzing a business process model to identify a plurality of activities and at least one transition criterion between the plurality of activities, where the business process model is unbounded to a physical implementation. The method also includes transforming the business process model into a three-dimensional virtual reality environment with virtual physical constraints, including a plurality of virtual rooms representing the plurality of activities and one or more virtual access points to the virtual rooms representing the at least one transition criterion. The method further includes outputting the three-dimensional virtual reality environment. | 05-10-2012 |
20130275184 | EXTERNALIZED DECISION MANAGEMENT IN BUSINESS APPLICATIONS - Within a business process, a decision reference can be defined at an insertion point. The decision reference can be associated with one of a plurality of different decision modes. Each decision mode can indicate a different process for selecting one or more activities of the business process to be performed according to a result of a decision service to be implemented for the decision reference. A description file can be generated for the decision reference specifying, at least in part, the associated decision mode. | 10-17-2013 |
20130275185 | EXTERNALIZED DECISION MANAGEMENT IN BUSINESS APPLICATIONS - Within a business process, a decision reference can be defined at an insertion point. The decision reference can be associated with one of a plurality of different decision modes. Each decision mode can indicate a different process for selecting one or more activities of the business process to be performed according to a result of a decision service to be implemented for the decision reference. A description file can be generated for the decision reference specifying, at least in part, the associated decision mode. | 10-17-2013 |
20140114864 | CASE MANAGEMENT INTEGRATION WITH EXTERNAL CONTENT REPOSITORIES - A case creation event originating from an external content repository is detected by a processor executing an inbound event handler of a distributed integration framework that integrates a case management system with the external content repository. The case creation event is configured by the distributed integration framework to cause creation of a case within the case management system. The inbound event handler instructs the case management system to create the case within the case management system. An outbound event handler of the distributed integration framework instructs the external content repository to create a proxy case to remotely represent the case created within the case management system. | 04-24-2014 |
20140114865 | CASE MANAGEMENT INTEGRATION WITH EXTERNAL CONTENT REPOSITORIES - A case creation event originating from an external content repository is detected by a processor executing an inbound event handler of a distributed integration framework that integrates a case management system with the external content repository. The case creation event is configured by the distributed integration framework to cause creation of a case within the case management system. The inbound event handler instructs the case management system to create the case within the case management system. An outbound event handler of the distributed integration framework instructs the external content repository to create a proxy case to remotely represent the case created within the case management system. | 04-24-2014 |
20140114918 | USE OF PROXY OBJECTS FOR INTEGRATION BETWEEN A CONTENT MANAGEMENT SYSTEM AND A CASE MANAGEMENT SYSTEM - Provided are techniques for synchronization. In response to an event that modifies a real object at a first content management system, another event is triggered to perform an action to modify a corresponding proxy object at a second content management system. In response to an event that modifies a real object at the second content management system, another event is triggered to perform an action to modify a corresponding proxy object at the first content management system. | 04-24-2014 |
20150088589 | CONVERTING A TEXT OPERATIONAL MANUAL INTO A BUSINESS PROCESS MODEL OR WORKFLOW DIAGRAM - Embodiments of the present invention disclose a method, computer program product, and system for generating a workflow diagram corresponding to text describing a business process. A computer identifies activities in steps of a business process by parsing text describing the business process. The computer determines activity names associated with the identified activities. The computer identifies roles associated with actors performing the identified activities. The computer identifies a sequence in which the identified activities are executed. The computer generates a workflow diagram of the business process based on the identified activities, determined activity names corresponding to the identified activities, identified roles associated with the identified activities, and the identified sequence in which the identified activities are executed. | 03-26-2015 |
20150088592 | CONVERTING A TEXT OPERATIONAL MANUAL INTO A BUSINESS PROCESS MODEL OR WORKFLOW DIAGRAM - Embodiments of the present invention disclose a method, computer program product, and system for generating a workflow diagram corresponding to text describing a business process. A computer identifies activities in steps of a business process by parsing text describing the business process. The computer determines activity names associated with the identified activities. The computer identifies roles associated with actors performing the identified activities. The computer identifies a sequence in which the identified activities are executed. The computer generates a workflow diagram of the business process based on the identified activities, determined activity names corresponding to the identified activities, identified roles associated with the identified activities, and the identified sequence in which the identified activities are executed. | 03-26-2015 |
Patent application number | Description | Published |
20110072436 | RESOURCE OPTIMIZATION FOR REAL-TIME TASK ASSIGNMENT IN MULTI-PROCESS ENVIRONMENTS - A novel and useful system and method of decentralized decision-making for real-time scheduling in a multi-process environment. For each process step and/or resource capable of processing a particular step, a service index is calculated. The calculation takes into account several measures, such as business level measures, operational measures and employee level measure. The decision of which process step a resource should next work on or what step to assign to a resource is based on the service index calculation and, optionally, other production factors. In one embodiment, the resource is assigned the process step with the maximal service index. Alternatively, when a resource becomes available, all process steps the resource is capable of processing are presented in order of descending service index. The resource then selects which process step to work on next. | 03-24-2011 |
20130311242 | Business Process Analytics - A system for visualizing a process includes a trace manager receiving a plurality of trace sets, each trace set having a plurality of business process execution traces, each of the business process execution traces being a representation of an individual work flow, a model generator creating a model from each of the trace sets, each model being a directed graph including a work flow of an aggregate of the business process execution traces in a respective trace set, a model comparator extracting a plurality of differences between the models and creating a comparison result based on the plurality of differences, wherein the comparison result is stored to a collaborative system, and a trace set identifier configured to identify a subset of the trace set based on a selected subsection of the model, where the subset of trace set exhibits at least one difference extracted from the selected subsection of the model. | 11-21-2013 |