Marijn
Marijn Gnirrep, Amsterdam NL
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20110138068 | Initiating an alternative communication channel for receiving streaming content - The invention relates to a device for either generating or maintaining an organic data network having an dynamic topology, comprising | 06-09-2011 |
Marijn Sandtke, Delfgauw NL
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20110188011 | PARTICLE CLEANING OF OPTICAL ELEMENTS FOR MICROLITHOGRAPHY - An optical assembly is mounted in a projection exposure apparatus ( | 08-04-2011 |
Marijn Sandtke, 'S-Gravenhage NL
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20160116414 | METHOD AND DETECTOR FOR DETECTING AN ANALYTE - The present disclosure concerns a method and detector ( | 04-28-2016 |
Marijn Sandtke, Delft NL
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20130229651 | OPTICAL PROBE COMPRISING TRANSPARENT MONOLITHIC BODY WITH REFRACTING AND REFLECTING SURFACE PARTS - The optical probe contains a monolithic body of optically transparent material to perform focusing for a plurality of parallel light paths from one or more fibers to one or more object points. Surface parts of the monolithic body are curved to form lenses and/or coated with a reflective coating. On a fiber side of the monolithic body an opening or openings are provided in a reflective coating opposite the tip or tips of the fibers to pass light. On the object side of the monolithic body, a coated surface part reflects the light path from the openings back to the fiber side of the monolithic body, from where the light path is reflected towards an aperture on the object side. At least part of the reflecting surfaces is curved to form reflector a plurality of distinct lenses on the same side of the monolithic body. | 09-05-2013 |
Marijn Van De Laarschot, Geldrop NL
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20140305322 | BALER AND METHOD OF BALING - A baler including a baling chamber that includes a bale-forming channel including an inlet end and an outlet end, a plunger mounted within the channel for compressing bale material in the channel and driving the compressed bale material towards the outlet end of the channel, and a rotary drive mechanism for driving reciprocating movement of the plunger, and an additional drive mechanism for driving the compressed bale material towards the outlet end of the channel, thereby reducing torque in the rotary drive mechanism. | 10-16-2014 |
Marijn Van De Laarschot, Pk Geldrop NL
Marijn Van Der Neut Kolfschote, Amsterdam NL
Patent application number | Description | Published |
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20100105874 | BISPECIFIC ANTIBODIES AND METHODS FOR PRODUCTION THEREOF - The invention relates to an ex vivo method for the generation of a bispecific antibody, comprising the steps of: a) providing a first antibody having a first binding specificity, wherein said first antibody comprises an IgG4-like CH3 region, b) providing a second antibody having a second binding specificity which differs from said first binding specificity, wherein said second antibody comprises an IgG4-like CH3 region, c) incubating said first and second antibodies together under reducing conditions which allow the cysteines in the core hinge region to undergo disulfidebond isomerization, and d) obtaining a bispecific antibody. The invention furthermore relates to bispecific antibodies obtainable by the method of the invention. | 04-29-2010 |
20100267934 | STABLE IGG4 ANTIBODIES - The present invention relates to stabilized IgG4 antibodies, to methods of producing such antibodies and to uses of such antibodies as a medicament. In a main aspect, the invention relates to a stabilized IgG4 antibody, comprising a heavy chain and a light chain, wherein said heavy chain comprises a human IgG4 constant region having a substitution of the Arg residue at position (409), the Phe residue at position (405) or the Lys residue at position (370). | 10-21-2010 |
Marijn Van Der Neut Kolfschoten, Amsterdam NL
Patent application number | Description | Published |
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20130345406 | STABLE IGG4 ANTIBODIES - The present invention relates to stabilized IgG4 antibodies, to methods of producing such antibodies and to uses of such antibodies as a medicament. In a main aspect, the invention relates to a stabilized IgG4 antibody, comprising a heavy chain and a light chain, wherein said heavy chain comprises a human IgG4 constant region having a substitution of the Arg residue at position (409), the Phe residue at position (405) or the Lys residue at position (370). | 12-26-2013 |
20150232537 | HUMAN BINDING MOLECULES CAPABLE OF BINDING TO AND NEUTRALIZING HEPATITIS B VIRUSES AND USES THEREOF - The disclosure relates to binding molecules, such as human monoclonal antibodies, that bind to Hepatitis B viruses, and have a broad neutralizing activity against such Hepatitis B viruses. The disclosure further provides nucleic acid molecules encoding the binding molecules, and compositions comprising the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of Hepatitis B. | 08-20-2015 |