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Mariagrazia Pizza, Siena IT

Mariagrazia Pizza, Siena IT

Patent application numberDescriptionPublished
20090232820NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from 09-17-2009
20090285845Domains And Epitopes Of Meningococcal Protein NMB1870 - ‘NMB1870’ is a known surface protein in 11-19-2009
20090298099Gonococcal Proteins and Nucleic Acids - The invention provides proteins from gonococcus (12-03-2009
20100015151POLYPEPTIDES FROM NEISSERIA MENINGITIDIS - Various specific meningococcal proteins are disclosed. The invention provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by meningococcus, such as bacterial meningitis.01-21-2010
20100015212IMMUNOGENIC BACTERIAL VESICLES WITH OUTER MEMBRANE PROTEINS - Knockout of the meningococcal mltA homolog gives bacteria that spontaneously release vesicles that are rich in immunogenic outer membrane proteins and that can elicit cross-protective antibody responses with higher bactericidal titres than OMVs prepared by normal production processes. Thus the invention provides a bacterium having a knockout mutation of its mltA gene. The invention also provides a bacterium, wherein the bacterium: (i) has a cell wall that includes peptidoglycan; and (ii) does not express a protein having the lytic transglycosylase activity of MltA protein. The invention also provides compositions comprising vesicles that, during culture of bacteria of the invention, are released into the culture medium.01-21-2010
20100105875Antibodies against neisserial factor H binding protein - Monoclonal antibody MAb502 binds to an epitope of meningococcal fHbp protein including Arg-204. Related antibodies are provided.04-29-2010
20100143418Immunising Against Meningococcal Serogroup Y Using Proteins - The invention uses polypeptide antigens and/or OMVs to immunize against serogroups A, C, W06-10-2010
20100166788IMMUNOGENS FROM UROPATHOGENIC ESCHERICHIA COLI - Disclosed herein are various polypeptides that can be included in immunogenic compositions specific for pathogenic 07-01-2010
20100233205ADJUVANTED ANTIGENIC MENINGOCOCCAL COMPOSITIONS - Compositions comprising a Neisserial antigen and a detoxified ADP-ribosylating toxin are provided. These compositions have been found useful for mucosal immunization, particularly for nasal immunization against 09-16-2010
20100267931HETEROLOGOUS EXPRESSION OF NEISSERIAL PROTEINS - Alternative and improved approaches to the heterologous expression of the proteins of 10-21-2010
20100272725Neisserial antigens - The invention provides proteins from 10-28-2010
20110008279Methods and Compositions Relating to Adhesins as Adjuvants - This invention is in the field of immunology and relates to the discovery that adhesins are potent activators of dendritic cells.01-13-2011
20110020390MENINGOCOCCAL FHBP POLYPEPTIDES - fHBP is a protein in 01-27-2011
20110076300Hybrid Polypeptides Including Meningococcal fHBP Sequences - fHBP is a protein in 03-31-2011
20110091492ESCHERICHIA COLI IMMUNOGENS WITH IMPROVED SOLUBILITY - Variants of the pathogenic 04-21-2011
20110104193COMBINATION NEISSERIAL COMPOSITIONS - Compositions comprising a first biological molecule from a 05-05-2011
20110166323CHIMERIC, HYBRID AND TANDEM POLYPEPTIDES OF MENINGOCOCCAL NMB1870 - NMB1870 is a protein in 07-07-2011

Patent applications by Mariagrazia Pizza, Siena IT