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Maria Pilar
Maria Pilar Civeira Murillo, Pamplona(navarra) ES
| Patent application number | Description | Published |
|---|---|---|
| 20090130055 | Use of a Cytokine From the Interleukin-6 Family In the Preparation of a Composition For Combined Administration With Interferon-Alpha - The invention relates to the use of at least one cytokine from the IL-6 family −gp130, preferably selected from among IL-11, the leukaemia inhibitory factor (LIF), oncostatin M (OSM), cardiotrophin-1, ciliary neurotrophic factor (CNTF), the cardiotrophin-like cytokine (CLC) and combinations thereof or a DNA sequence encoding same, in the preparation of a pharmaceutical composition which is intended for combined administration with at least one IFN-α or a DNA sequence encoding same, for use in the treatment of viral diseases. The invention also relates to a pharmaceutical composition comprising a pharmaceutically-acceptable quantity of at least one cytokin from the IL-6 family −gp130 or a DNA sequence encoding same and a pharmaceutically-acceptable quantity of at least one IFN-α or a DNA sequence encoding same, a pharmaceutical kit and a method for the treatment of viral diseases with the combined administration of the aforementioned cytokines and IFN-α. | 05-21-2009 |
Maria Pilar De Frutos Escrig, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20110121228 | REVALUATION OF AQUEOUS WASTE STREAMS IN THE PROPYLENE OXIDE/STYRENE CO-PRODUCTION PROCESS - The present disclosure describes a method for the revaluation of aqueous waste streams generated in the propylene oxide and styrene co-production processes. In particular, it discloses a method of reducing the organic contaminant load from a highly contaminated aqueous stream and recovery from said stream of organic compounds that may be recirculated or used as fuel in the co-generation of energy, and which comprises: acidification of said aqueous stream with inorganic acid at a pH less than 4.5; separation of the two resulting phases at a temperature greater than 40° C.; washing of the organic phase produced in the previous step with an aqueous solution of excess acid and separation of the two resulting phases. | 05-26-2011 |
Maria Pilar Garcia-Pareja, Alhendin (granada) ES
| Patent application number | Description | Published |
|---|---|---|
| 20090018194 | Use of antimicrobial agents derived from alliaceous plants for the prevention and control of crop diseases, post-harvest rot and as environmental disinifectant products - The present invention is directed to utilization of antimicrobial agents derived from plants of the alliaceae family for the prevention and control of crop diseases, post-harvest rotting and as environmental disinfection products. The agents include propyl propylthiosulfinate and propyl propylthiosulfonate compounds for pre- and post-harvest treatments, control of rotting in fruits and vegetables; disinfection of agricultural soils, control of microorganisms, environmental disinfection in agricultural processing industries, facilities and equipment, disinfection of food containers and boxes. The agents can be used as pure active principles or in mixtures, in aqueous solutions or in any formulation, either liquid or supported in a solid agent or formulation; as single active principles or in formulation, together with other synthetic or natural antifungal agents, biocontrol agents, fertilizers, antioxidants, growth regulators or regulators of any other type; by means of immersion, fogging, wetting, spraying, atomization, injection in the soil, in irrigation systems, by means of drenchers or in general any other treatment or application system. | 01-15-2009 |
Maria Pilar Gimeno Tolosa, Zaragoza ES
| Patent application number | Description | Published |
|---|---|---|
| 20110160507 | METHOD FOR OBTAINING AROMATIC HYDROCARBONS FROM METHANE - Process for obtaining aromatic hydrocarbons from a stream containing at least one light hydrocarbon selected from the list comprising methane, ethane, ethylene, propane, propene, propylene, butane, butene or butadiene, which comprises putting said stream into contact with a catalyst, which comprises a catalytic material and a binder, in a fluidized bed reactor. Said reactor may have two reaction zones, an oxidizing zone and a reducing zone. | 06-30-2011 |
| 20110184191 | TWO-ZONE FLUIDISED-BED REACTOR | 07-28-2011 |
Maria Pilar González López, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20110270807 | Method In A Database Server - Method, apparatus and computer program for storing by a database server a plurality of data entries containing data related to a plurality of applications. The database server receives a request to modify the content of a data entry and checks a validation rule related to the entry before performing the modification. The validation rule contains information usable for determining valid data contents that can be stored in said entry, and information for building the validation rule is received from one or more application servers serving said applications. When a back end database server system stores data related to a plurality of applications, data validation check mechanisms are simplified, as information for performing validity checks are received from the application servers in the database system. | 11-03-2011 |
Maria Pilar Lopez Deber, Ecublens CH
| Patent application number | Description | Published |
|---|---|---|
| 20100144793 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS - The present invention relates to compounds of the general formula (I) wherein (formula 2) independently represents a single bond or a double bond, represents a linking group A and A′ are each independently a 5- to 7-membered heterocyclic ring, wherein the heterocyclic rings A und A′ are optionally substituted by one or more substituents, selected from C | 06-10-2010 |
| 20100183513 | N-(METHYL) -1H-PYRAZOL-3-AMINE, N-(METHYL)-PYRIDIN-2-AMINE AND N-(METHYL)-THIAZOL-2-AMINE DERIVATIVES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS, LIKE E.G. ALZHEIMER'S - The present invention relates to novel compounds of formula (II) that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and of diseases or conditions associated with amyloid-like proteins. The compounds of the present invention can also be used in the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system. The present invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the preparation of medicaments for treating, or preventing diseases or conditions associated with amyloid and/or amyloid-like proteins. A method of treating or preventing diseases or conditions associated with amyloid and/or amyloid-like proteins is also disclosed. | 07-22-2010 |
Maria Pilar Munoz Lopez, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20080265093 | Integrated multispar torsion box of composite material - The invention relates to an integrated multispar torsion box structure of composite material for aircraft, comprising a lower skin ( | 10-30-2008 |
| 20090001218 | Stifffened multispar torsion box - The invention relates to an integrated structure of a composite material multispar torsion box ( | 01-01-2009 |
Maria Pilar Pizcueta Lalanza, Barcelona ES
| Patent application number | Description | Published |
|---|---|---|
| 20110129445 | COMBINATIONS COMPRISING METHOTREXATE AND DHODH INHIBITORS - The present disclosure relates to combinations comprising (a) methotrexate, and (b) a DHODH inhibitor and their uses. | 06-02-2011 |
| 20110280831 | COMBINATIONS COMPRISING METHOTREXATE AND DHODH INHIBITORS - The present invention provides a combination which comprises (a) methotrexate and (b) a non-hepatotoxic DHODH inhibitor of formula (I): wherein: R | 11-17-2011 |
Maria Pilar Rodriguez Molto, Ciudad De La Habana CU
| Patent application number | Description | Published |
|---|---|---|
| 20090304633 | CHIMERIC VACCINE ANTIGENS AGAINST CLASSICAL SWINE FEVER VIRUS - The current invention describes chimeric vaccine antigens against the virus that causes the Classic Swine Fever (CSFV). Such vaccine antigens are based on viral subunits coupled to proteins able to stimulate cellular and humoral immune system. Chimeric antigens can be produced in expression systems that guarantee a correct tertiary structure folding of the chimeric molecules, which constitute the essence of the current invention. The vaccine formulations containing such chimeric antigens induce an early and potent immune response on vaccinated pigs and confer full protection against CSFV. Moreover, the resultant vaccine formulations prevent the viral transmission from sows to their offspring. The chimeric antigens, as well as the resultant vaccine formulations, can be applied in animal health as vaccines for preventive use in swine. | 12-10-2009 |
| 20090324644 | CHIMERIC VACCINE ANTIGENS AGAINST THE AVIAN INFLUENZA VIRUS - The present invention describes chimeric vaccine antigens against the avian influenza virus (AIV). Said vaccine antigens are based on viral subunits that are coupled to protein molecules that stimulate not only the cellular but also the humoral immune system. The chimeric antigens may be produced in expression systems that guarantee correct three-dimensional folding of the chimeric molecules that constitute the basis of the present invention. The vaccine compositions that contain said chimeric antigens induce a potent, early immune response both in birds and in vaccinated mammals, stimulating high haemagglutinin-inhibiting antibody titres and a potent specific cellular response against the viral antigen. The chimeric antigens, and also the resulting vaccine compositions, are applicable to the field of human and animal health as vaccines for preventive use. | 12-31-2009 |
Maria Pilar Saenz Jimenez, Derio ES
| Patent application number | Description | Published |
|---|---|---|
| 20080274968 | IN VITRO METHODS FOR DETECTING RENAL CANCER - The present invention refers to an in vitro method for detecting the presence of renal cancer in an individual, for determining the stage, malignancy or severity of said carcinoma in the individual or for monitoring the effect of the therapy administered to an individual having said cancer; to the search, identification, development and assessment of the efficacy of compounds for therapy for said cancer in an attempt to develop new drugs; as well as to agents inducing Plexin-131 protein expression and/or activity, or to agents inhibiting the effects of Plexin-B1 protein expression and/or activity repression. | 11-06-2008 |
| 20110098191 | IN VITRO METHODS FOR DETECTING RENAL CANCER - The present invention refers to an in vitro method for detecting the presence of renal cancer in an individual, for determining the stage, malignancy or severity of said carcinoma in the individual or for monitoring the effect of the therapy administered to an individual having said cancer; to the search, identification, development and assessment of the efficacy of compounds for therapy for said cancer in an attempt to develop new drugs; as well as to agents inducing Plexin-131 protein expression and/or activity, or to agents inhibiting the effects of Plexin-B1 protein expression and/or activity repression. | 04-28-2011 |
Maria Pilar Villanueva Redon, Valencia ES
| Patent application number | Description | Published |
|---|---|---|
| 20110288224 | Polymeric Matrix Nanocomposite Materials Having Improved Mechanical and Barrier Properties and Procedure For Preparing Same - The present invention relates to nanocomposite materials based on a polymeric or plastic matrix and a laminar silicate (clay) having improved mechanical, thermal and gas-barrier properties, among others, and not requiring clay-matrix compatibilising agents. Furthermore the present invention relates to three procedures for the obtainment of these materials and use thereof for applications such as in packaging products of interest to the food sector, among others, and for applications in other sectors. | 11-24-2011 |
Maria Pilar Zaragoza Fernández, Zaragoza ES
| Patent application number | Description | Published |
|---|---|---|
| 20100261656 | Therapeutic Use of the Encoding Sequence of the Carboxy-Terminal Domain of the Heavy Chain of the Tetanus Toxin - The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS). | 10-14-2010 |
Maria Pilar Zaragoza Fernández, Zaragoza ES
| Patent application number | Description | Published |
|---|---|---|
| 20100261656 | Therapeutic Use of the Encoding Sequence of the Carboxy-Terminal Domain of the Heavy Chain of the Tetanus Toxin - The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS). | 10-14-2010 |
María Pilar Civeira Murillo, Pamplona (navarra) ES
| Patent application number | Description | Published |
|---|---|---|
| 20110027224 | USE OF A CYTOKINE FROM THE INTERLEUKIN-6 FAMILY IN THE PREPARATION OF A COMPOSITION FOR COMBINED ADMINISTRATION WITH INTERFERON-ALPHA - The invention relates to the use of at least one cytokine from the IL-6 family −gp130, preferably selected from among IL-11, the leukaemia inhibitory factor (LIF), oncostatin M (OSM), cardiotrophin-1, ciliary neurotrophic factor (CNTF), the cardiotrophin-like cytokine (CLC) and combinations thereof or a DNA sequence encoding same, in the preparation of a pharmaceutical composition which is intended for combined administration with at least one IFN-α or a DNA sequence encoding same, for use in the treatment of viral diseases. The invention also relates to a pharmaceutical composition comprising a pharmaceutically-acceptable quantity of at least one cytokin from the IL-6 family −gp130 or a DNA sequence encoding same and a pharmaceutically-acceptable quantity of at least one IFN-α or a DNA sequence encoding same, a pharmaceutical kit and a method for the treatment of viral diseases with the combined administration of the aforementioned cytokines and IFN-α. | 02-03-2011 |
María Pilar Goya-Laza, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20090221710 | Acyclic Sulfamide Derivatives - The present invention is related to acyclic sulfamide derivatives, useful for the manufacture of a medicament for satiety induction and ingestion control, corporal fat modulation and lipidic metabolism regulation and for the manufacture of a medicament for the treatment or prevention of diabetes and cardiovascular diseases. The acyclic sulfamide derivatives are also useful for cosmetic use. | 09-03-2009 |
| 20100004224 | 1,2,4-TRIAZOLE DERIVATIVES AS SIGMA RECEPTOR INHIBITORS - The invention relates to the use of compounds having pharmacological activity towards the sigma receptor, and more particularly to 1,2,4-triazole derivatives of formula (I) to processes of preparation of such compounds and to pharmaceutical compositions comprising them. | 01-07-2010 |
| 20100004265 | 1,2,3-TRIAZOLE DERIVATIVES AS SIGMA RECEPTOR INHIBITORS - The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to 1,2,3-triazole derivatives of formula (I) and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis or pain. | 01-07-2010 |
| 20100048712 | Acyclic Sulfamide Derivatives - The present invention is related to acyclic sulphamide derivatives of formula (I), wherein R | 02-25-2010 |
| 20100179224 | Acyclic Sulfamide Derivatives - The present invention is related to acyclic sulphamide derivatives of formula (I), wherein R | 07-15-2010 |
María Pilar Marco Colas, Barcelona ES
| Patent application number | Description | Published |
|---|---|---|
| 20100193378 | IMPEDIMETRIC SENSOR AND APPLICATIONS THEREOF - The invention relates to a highly sensitive impedimetric sensor in which the highly conductive electrodes are separated by a barrier of insulating material. Said sensor is used to determine directly the presence of analytes in a biological sample of human, veterinary or environmental origin. | 08-05-2010 |