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Maria Pia

Maria Pia Abbracchio, Milano IT

Patent application numberDescriptionPublished
20090156521Gpr17 modulators,method of screening and uses thereof - The invention provides GPR17 modulators, methods of screening and use thereof for diagnosis and therapy of diseases or dysfunctions involving GPR17 activation, particularly ischemic brain damage.06-18-2009

Maria Pia Arolfo, Pleasanton, CA US

Patent application numberDescriptionPublished
20080207610ALDH-2 INHIBITORS IN THE TREATMENT OF ADDICTION - Disclosed are novel isoflavone derivatives having the structure of Formula I08-28-2008
20090209533ALDH-2 INHIBITORS IN THE TREATMENT OF ADDICTION - Disclosed are novel isoflavone derivatives having the structure of Formula I08-20-2009

Maria Pia Cosma, Salerno IT

Patent application numberDescriptionPublished
20100311170METHOD FOR REPROGRAMMING DIFFERENTIATED CELLS - The present invention discloses a method for reprogramming a differentiated cell to an undifferentiated stem cell comprising fusing a pluripotent cell with a differentiated cell to form a fused cell, wherein the pluripotent cell is pre-treated or the fused cell is treated with a suitable amount of a Wnt/β-catenin pathway activator.12-09-2010

Maria Pia Rastaldi, Rho IT

Patent application numberDescriptionPublished
20080214458SYNAPSE-SPECIFIC PROTEINS IN GLOMERULI - The present invention identifies that glomeruli express many neuron-specific and especially synapse-specific protein similarities. In particular, the present invention identifies Rab3A expression, including the expression of altered forms, as well as expression of other synapse-specific proteins including neurotransmitter receptors. The invention further identifies that modulation of the activity of these synapse-specific proteins results in modulation of podocytes.09-04-2008

Maria Pia Zappavigna, Magenta IT

Patent application numberDescriptionPublished
20090209506AMINO DERIVATIVES OF BETA-HOMOANDROSTANES AND BETA-HETEROANDROSTANES - New aminoalkoxyimino derivatives at position 3 of substituted B-homoandrostanes and B-heteroandrostanes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.08-20-2009
20110053902AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS - Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart failure and hypertension. The compounds are inhibitors of the enzymatic activity of the Na03-03-2011