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Maria Emilia Di Francesco

Maria Emilia Di Francesco, Rome IT

Patent application numberDescriptionPublished
20090258891Macrocyclic Compounds As Antiviral Agents - The present invention relates to macrocyclic compounds of formula (I): wherein W, n, R10-15-2009
20100099695HCV NS3 Protease Inhibitors - The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.04-22-2010
20100183551Macrocyclic Compounds As Antiviral Agents - A class of macrocyclic compounds of formula (I), wherein R07-22-2010
20100210581Nucleoside Derivatives as Inhibitors of Viral Polymerases - A class of nucleoside derivatives of formula (I), as defined herein, that are useful as inhibitors of RNA-dependent RNA viral replication and in particular HCV replication, are provided. Also provided are processes for the synthesis and use of such compounds for treating or preventing HCV infection.08-19-2010
20100298210HCV NS3 Protease Inhibitors - The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use treating or preventing HCV infections.11-25-2010

Maria Emilia Di Francesco, Brookline, MA US

Patent application numberDescriptionPublished
20110245205AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.10-06-2011
20110306573NUCLEOSIDE DERIVATIVES AS INHIBITORS OF VIRAL POLYMERASES - Compounds of structural formula (I): and pharmaceutically acceptable salts thereof; wherein R12-15-2011
20120010164ANTIVIRAL AGENTS - Compounds of structural formula (I): and pharmaceutically acceptable salts thereof; as defined herein, are described for use in the prevention and/or treatment of HCV infections. Novel compounds of the formula (I) and pharmaceutical formulations containing them are also described.01-12-2012