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Maria A.

Maria A. Apecetche, Bridgewater, NJ US

Patent application numberDescriptionPublished
20080214388Methods to prepare catalyst compositions comprising small silica support materials - Methods are provided to prepare a catalyst system that includes at least one titanium compound, at least one magnesium compound, at least one electron donor compound, at least one activator compound, and at least one silica support material, the at least one silica support material having a median particle size in the range of from 20 to 50 microns with no more than 10% of the particles having a size less than 10 microns and no more than 10% of the particles having a size greater than 50 microns and average pore diameter of at least ≧220 angstroms.09-04-2008
20080242821Hindered polyalicyclic alkyl catalysts and their use in a gas-phase polymerization reactor - Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition. In one embodiment, the hindered polyalicyclic alkyl catalyst precursor is formed by first combining an acid, a compound having the formula RX, and a metal oxide selected from the group consisting of Group 3 to Group 10 oxide compounds to produce a catalyst precursor; characterized in that R is selected from the group consisting of hindered polyalicyclic alkyls, and substituted derivatives thereof, and X is selected from the group consisting of any suitable leaving group.10-02-2008
20090215970Blow Molding Polyethylene Resins - Disclosed herein are various processes, including continuous fluidized-bed gas-phase polymerization processes for making a high strength, high density polyethylene copolymer, comprising (including): contacting monomers that include ethylene and optionally at least one non-ethylene monomer with fluidized catalyst particles in a gas phase in the presence of hydrogen gas at an ethylene partial pressure of 100 psi or more and a polymerization temperature of 120° C. or less to produce a polyethylene copolymer having a density of 0.945 g/cc or more and an ESCR Index of 1.0 or more wherein the catalyst particles are prepared at an activation temperature of 700° C. or less, and include silica, chromium, and titanium.08-27-2009
20100137533HINDERED POLYALICYCLIC ALKYL CATALYSTS AND THEIR USE IN A GAS-PHASE POLYMERIZATION REACTOR - Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition. In one embodiment, the hindered polyalicyclic alkyl catalyst precursor is formed by first combining an acid, a compound having the formula RX, and a metal oxide selected from the group consisting of Group 3 to Group 10 oxide compounds to produce a catalyst precursor; characterized in that R is selected from the group consisting of hindered polyalicyclic alkyls, and substituted derivatives thereof, and X is selected from the group consisting of any suitable leaving group.06-03-2010
20100160580Blow molding Polyethylene Resins - Disclosed herein are various processes, including continuous fluidized-bed gas-phase polymerization processes for making a high strength, high density polyethylene copolymer, comprising (including): contacting monomers that include ethylene and optionally at least one non-ethylene monomer with fluidized catalyst particles in a gas phase in the presence of hydrogen gas at an ethylene partial pressure of 100 psi or more and a polymerization temperature of 105° C. or less to produce a polyethylene copolymer having a density of 0.945 g/cc or more and an ESCR Index of 1.0 or more wherein the catalyst particles are prepared at an activation temperature of 700° C. or less, and include silica, chromium, and titanium.06-24-2010

Patent applications by Maria A. Apecetche, Bridgewater, NJ US

Maria A. Appeaning, St. Paul, MN US

Patent application numberDescriptionPublished
20120070342LIGHT-ACTIVATED ANTIMICROBIAL ARTICLES AND METHODS OF USE - A light-activated antimicrobial article is disclosed, consisting essentially of an acridine dye covalently bonded without a linking group to a nylon material. The article may be made using electron beam processing. The article in combination with light absorbed by the acridine dye may be used to inhibit the growth of microorganisms. A photosensitive nylon material in which the acridine dye is disposed on the nylon material may also be used. Medical kits that include a light source and an article having the acridine dye are disclosed.03-22-2012

Maria A. Argiriadi, Wayland, MA US

Patent application numberDescriptionPublished
20090202557Compositions and methods for crystallizing antibody fragments - The invention provides methods of crystallizing antibodies and fragments thereof as well as crystals produced thereby. More particularly, the invention provides methods of crystallizing human and non-human Fab fragments of antibodies, either alone or as co-crystals with their target ligand. For example, a crystal comprising a murine Fab fragment of the antibody 125-2H or a human Fab fragment of the antibody ABT-325, which bind to IL-18, are provided as well as a co-crystal of a murine Fab fragment bound to IL-18. ABT-325 and 125-2H differ significantly in combining site character and architecture, thus explaining their ability to bind IL-18 simultaneously at distinct epitopes.08-13-2009
20090312338Novel Tricyclic Compounds - The invention provides a compound of Formula (I)12-17-2009
20110165066INTERLEUKIN-13 BINDING PROTEINS - The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-13 and neutralize hIL-13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-13 and for inhibiting hIL-13 activity, e.g., in a human subject suffering from a disorder in which hIL-13 activity is detrimental.07-07-2011
20110190489Novel Tricyclic Compounds - The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.08-04-2011
20110311474Novel Tricyclic Compounds - The invention provides compounds of Formula (I) and Formula (II)12-22-2011

Patent applications by Maria A. Argiriadi, Wayland, MA US

Maria A. Bonzagni, Marshfield, MA US

Patent application numberDescriptionPublished
20080276348Golf Glove with a Compartment - A combination golf glove and container, with a hinged lid, that allows a golfer to carry and access agents such as lip balm, lotion, or grip enhancing material while playing a round of golf In one embodiment, the hinged lid of the container has a ball marker holder for detachably securing a ball marker of ferromagnetic material to a magnet embedded within a holder.11-13-2008

Maria A. Dannemiller, Liberty Township, OH US

Patent application numberDescriptionPublished
20110032551SYSTEM, METHOD AND SOFTWARE FOR REDUCING PRINTER COLORANT USAGE - A system, method, and printer controller software for reducing printer colorant usage by using printer controller software which controls the deposition by the printer of the printer colorant on the printable medium in response to selected print image quality and printer colorant reduction criteria, as well as identifying printer colorant deposition characteristics of the printable medium, identifying characteristics of the printer, and identifying characteristics of the printer colorant.02-10-2011

Maria A. Del Solar, Stamford, CT US

Patent application numberDescriptionPublished
20110289733TEETHER/PACIFIER SECURING DEVICE - A securing device connected to a tether including a first clamp portion and a second clamp portion each having a respective first or second exterior surface and interior surface opposite the exterior surface. The first and second clamp portions each have an end that is connected to one another at a connected portion and an opposite free end that is free to form a “C” shape. The connected portion connects the first and second clamp portions to bias the free ends away from each other. A slider is movably connected to the first and second clamp portions so that the slider moves toward and away from the free ends. A ridge is connected to the second exterior surface adjacent the free end of the second clamp portion so that the ridge protrudes from the second exterior surface to be engaged by a user while moving the slider.12-01-2011

Maria A. Parfenova, Mountain View, CA US

Patent application numberDescriptionPublished
20100292592System and method of measuring changes in arterial volume of a limb segment - A medical diagnostic device performs diagnostics for assessing the ability of the arteries to respond to an increase in blood flow. The medical diagnostic device determines relative changes in arterial volume of the limb segment during a time period after a stimulus relative to the arterial volume of the limb segment during a baseline period using the amplitudes or other portions of the component pulse waves (such as early systolic components) of volume pulse waves during the baseline period and after the stimulus.11-18-2010

Maria A. Vishniakova, Moscow RU

Patent application numberDescriptionPublished
20100047738Device for Forming a Bone Bed for Dental Implants - A device for forming a bone bed for dental implants having a head composed of crystal of partially stabilized zirconium dioxide with a nanostructure having a crystallographic axis that coincides with the axis of the bone bed forming device. The head has cutting elements formed as a rotatable plate. The plate has two broad facets formed by circular arcs that are convex relative to the axis of bone bed forming device. Transition from one of the convex circular arc to another convex circular arc is smoothed by circular arcs that are concave relative to the axis of bone bed forming device. Grooves form first and second cutting members with narrow facets of the plate. The head has an end part shaped as a truncated sphere possessing a recess formed by two planes arranged at an angle of 90° relative to each other and passing through the truncated sphere center and two points belonging to two diagonally arranged plate ribs. A third cutting member is formed by the intersection of one of the above mentioned two planes and a spherical surface of one of the narrow plate facets of the end part of the head.02-25-2010

Maria A. Vishnyakova, Moscow RU

Patent application numberDescriptionPublished
20110105295Zirconium dioxide-based material - The invention relates to the field of synthetic materials and is industrially applicable in the manufacture of wear-resistant construction parts for use under conditions of elevated temperatures, loads, and aggressive media, for cutting and machining tools, and in medical equipment. The technical problem of optimization of the performance parameters of the material, including crack resistance, hardness, and wear resistance, is solved. The objective is achieved by the fact that a material based on zirconium dioxide, containing yttrium and obtained by directed crystallization from batch mixture melted in a cold container, contains at least two tetragonal phases whose axes of tetragonality are 80-90°. The components of the batch mixture for obtaining the material are contained in the following ratio (in mol %): yttrium oxide, 2.8-3.7; zirconium dioxide, the remainder. To obtain the material, a thermal insulating layer 05-05-2011

Maria A. Vitiello, La Jolla, CA US

Patent application numberDescriptionPublished
20090311283Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions - This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.12-17-2009
20110097352Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions - This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.04-28-2011

Patent applications by Maria A. Vitiello, La Jolla, CA US