Manuel F.
Manuel F. Balandrin, Sandy, UT US
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20110046128 | NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS - A series of novel compounds showing anticonvulsant, chemical countermeasure(s), and analgesic activities is described. Such pharmaceutically active compounds may also show utility in the treatment of other central nervous system (“CNS”) diseases and disorders, such as anxiety, depression, insomnia, migraine headaches, schizophrenia, Parkinson's disease, spasticity, Alzheimer's disease, and bipolar disorder. Furthermore, such compounds may additionally find utility as analgesics (e.g., for the treatment of chronic or neuropathic pain) and as neuroprotective agents useful in the treatment of stroke(s), chronic neurodegenerative diseases (such as Alzheimer's disease and Huntington's disease), and/or traumatic brain and/or spinal cord injuries. Moreover, these/such compounds may also be useful in the treatment of status epilepticus and/or as chemical countermeasures. | 02-24-2011 |
20130190407 | CALCIUM RECEPTOR-ACTIVE MOLECULES - The present invention relates to the different roles inorganic ion receptors have in cellular and body processes. The present invention features: (1) molecules which can modulate one or more inorganic ion receptor activities, preferably the molecule can mimic or block an effect of an extracellular ion on a cell having an inorganic ion receptor, more preferably the extracellular ion is Ca | 07-25-2013 |
Manuel F. Cabanas-Holmen, Mckenna, WA US
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20150070062 | Filtered Radiation Hardened Flip Flop with Reduced Power Consumption - A flip flop circuit has a first stage and a second stage. The first stage and the second stage each have interleaved filters. | 03-12-2015 |
Manuel F. Cabanas-Holmen, Roy, WA US
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20110025372 | METHOD AND APPARATUS FOR REDUCING RADIATION AND CROSS-TALK INDUCED DATA ERRORS - The different advantageous embodiments provide an integrated circuit comprising a number of latches and a number of filters. Each latch in the number of latches has a plurality of inputs and a plurality of storage nodes. The plurality of storage nodes includes a number of pairs of circuit nodes that form a number of upsettable circuit node pairs. Each input of the plurality of inputs is connected to a corresponding storage node in the plurality of storage nodes. Each filter in the number of filters has an input and a plurality of outputs. Each of the plurality of outputs is connected to a corresponding input of the plurality of inputs of a latch in the number of latches. Each filter in the number of filters is located between two circuit nodes forming an upsettable circuit node pair of the latch in the number of latches to increase critical node spacing. | 02-03-2011 |
20110309856 | METHOD AND APPARATUS FOR REDUCING RADIATION AND CROSS-TALK INDUCED DATA ERRORS - The different advantageous embodiments provide an integrated circuit comprising a number of latches and a number of filters. Each latch in the number of latches has a plurality of inputs and a plurality of storage nodes. The plurality of storage nodes includes a number of pairs of circuit nodes that form a number of upsettable circuit node pairs. Each input of the plurality of inputs is connected to a corresponding storage node in the plurality of storage nodes. Each filter in the number of filters has an input and a plurality of outputs. Each of the plurality of outputs is connected to a corresponding input of the plurality of inputs of a latch in the number of latches. Each filter in the number of filters is located between two circuit nodes forming an upsettable circuit node pair of the latch in the number of latches to increase critical node spacing. | 12-22-2011 |
Manuel F. Cabanas-Holmen, Seal Beach, CA US
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20140132332 | INTERLEAVED TRANSIENT FILTER - An interleaved filter circuit has a delay element configured to receive an input signal. An interleaved output buffer has a first input which receives the input signal and a second input which receives the output of the delay element. An output of the interleaved output buffer is driven when the first input and the second input are at a same logic level. | 05-15-2014 |
Manuel F. GonzÁlez Penedo, Santiago De Compostela ES
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20120195480 | METHOD, APPARATUS, AND SYSTEM FOR RETINAL IMAGE ANALYSIS - Disclosed embodiments include a method for retinal image analysis implemented in a medical system with one or more processors comprising the method steps of: (a) locating an optical disk on the retinal images and establishing a plurality of circumferences centered at the disk; (b) detecting a plurality of vessels within a region defined by said circumferences' radii using a crease-based algorithm; (c) extracting a plurality of vessel segments based on a deformable models (snakes) algorithm; (d) measuring a plurality of vessel calibers; (e) classifying each vessel as a vein and an artery; and (f) computing an arteriolar-to-venular ratio. | 08-02-2012 |
Manuel F. Juette, Rosrath DE
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20090242798 | 3D Biplane Microscopy - A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data. | 10-01-2009 |
20100265318 | 3D Biplane Microscopy - A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data. | 10-21-2010 |
20110025831 | 3D Biplane Microscopy - A microscopy system is configured for creating 3D images from individually localized probe molecules. The microscopy system includes a sample stage, an activation light source, a readout light source, a beam splitting device, at least one camera, and a controller. The activation light source activates probes of at least one probe subset of photo-sensitive luminescent probes, and the readout light source causes luminescence light from the activated probes. The beam splitting device splits the luminescence light into at least two paths to create at least two detection planes that correspond to the same or different number of object planes of the sample. The camera detects simultaneously the at least two detection planes, the number of object planes being represented in the camera by the same number of recorded regions of interest. The controller is programmable to combine a signal from the regions of interest into a 3D data. | 02-03-2011 |
Manuel F. Salvel, Schaffhausen CH
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20080264290 | Bullet - A projectile ( | 10-30-2008 |