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Manske, US

Joy L. Manske, Menomonie, WI US

Patent application numberDescriptionPublished
20090021831PRISMATIC RETROREFLECTIVE ARTICLE WITH CROSS-LINKED IMAGE LAYER AND METHOD OF MAKING SAME - A prismatic retroreflective article and a method for making same. The retroreflective article can include a transparent polymeric body portion, an optical layer coupled to the body portion, and an image layer coupled to the body portion opposite the optical layer. The image layer can define imaged portions and non-imaged portions of the prismatic retroreflective article. The image layer can include cross-links formed between a polymer resin having hydroxyl functional groups and a cross-linking agent having isocyanate functional groups. The image layer can have a percent elongation of at least 80 percent and less than 200 percent. The method can include printing or coating an image layer onto to the body portion of the retroreflective sheeting opposite the optical layer, and cross-linking the image layer to form cross-links between the hydroxyl functional groups of the polymer resin and the isocyanate functional groups of the cross-linking agent.01-22-2009

Karl J. Manske, Minneapolis, MN US

Patent application numberDescriptionPublished
20080318998Alkyloxy Substituted Thiazoloquinolines and Thiazolonaphthyridines - Thiazoloquinolines and thiazolonaphthyridines with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.12-25-2008
20090029988Hydroxyalkyl Substituted Imidazoquinolines - Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-α biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.01-29-2009
20090030031Method of Preferentially Inducing the Biosynthesis of Interferon - A method of preferentially inducing IFN-α biosynthesis in an animal comprising administering certain imidazo[4,5-c] ring compounds with a hydroxymethyl or hydroxyethyl substituent at the 2-position or pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of using these compounds a immunomodulators for treatment of diseases including viral and neoplastic diseases comprising preferentially inducing IFN-α biosynthesis in an animal are disclosed.01-29-2009
200902704431-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS - Imidazo-containing compounds (e.g., imidazonaphthyridines, imidazopyridines) with an amino substituent at the 1-position, pharmaceutical compositions containing the compounds and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.10-29-2009

Patent applications by Karl J. Manske, Minneapolis, MN US

Karl J. Manske, Saint Paul, MN US

Patent application numberDescriptionPublished
20090221551SUBSTITUTED FUSED[1,2] IMIDAZO[4,5C] RING COMPOUNDS AND METHODS - [1,2]Imidazo[4,5-c] ring compounds (e.g., imidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and imidazo[4,5-c]pyridines) substituted with a fused ring containing an oxygen and/or nitrogen atom attached at the 1- and/or 2-position, pharmaceutical compositions containing the compounds, intermediates, methods of making the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.09-03-2009

Scott D. Manske, Charlotte, NC US

Patent application numberDescriptionPublished
20080261840Remediation of Microfloral and Biofilm Development From Laundering Devices - Methods, improved compositions and kits are employed that provide dosing and cleaning solutions containing a halogen-based oxidant effectively delivered to remediate microfloral and biofilm development on the laundering surfaces of enclosed horizontal axis washers. The improved compositions, and the methods and kits employing them, provide for effective remediation while minimizing and/or preventing detrimental effects upon halogen-susceptible surfaces of the laundering devices, including reduced corrosion and biofilm on interior metal and laundering surfaces.10-23-2008
20090253605Remediation of Microfloral and Biofilm Development From Laundering Devices - Methods, improved compositions and kits are employed that provide dosing and cleaning solutions containing a halogen-based oxidant effectively delivered to remediate microfloral and biofilm development on the laundering surfaces of enclosed horizontal axis washers. The improved compositions, and the methods and kits employing them, provide for effective remediation while minimizing and/or preventing detrimental effects upon halogen-susceptible surfaces of the laundering devices, including reduced corrosion and biofilm on interior metal and laundering surfaces.10-08-2009

Scott D. Manske, Pleasanton, CA US

Patent application numberDescriptionPublished
20090075250Environmental Sampling and Testing Method - Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base. The wick transfers at least a portion of analyte and the elution solvent to the lateral flow strip for the calorimetric detection of specific allergens, viruses, bacteria, and other protein containing substances in the sample. The calorimetric results of the test are displayed through a window in the base.03-19-2009

Patent applications by Scott D. Manske, Pleasanton, CA US