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Manon

Manon Chaumontet, Toulouse FR

Patent application numberDescriptionPublished
20100016580Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the preparation of compounds of formula (IV):01-21-2010

Manon Turlan, Marmagne FR

Patent application numberDescriptionPublished
20110076408MOULDED TEXTILE LINGERIE ITEM WITH SUPPORT REGION MADE FROM SILICONE - An article made of elastic textile material comprising at least one zone intended to be shaped by thermal molding is provided. The at least one zone has at least over one part a support region in which the textile material is coated, prior to thermal molding, with a non-moldable material with shape-memory. The article is, in particular, a brassiere coated with silicone in the zone of the cups of the brassiere.03-31-2011

Manon Van Engeland, Maastricht NL

Patent application numberDescriptionPublished
20100144836Methods for Detecting Epigenetic Modifications - A method of detecting a predisposition to, or the incidence of, cancer in a sample comprises detecting an epigenetic change in at least one gene selected from an NDRG4/NDRG2 subfamily gene, GATA4, OSMR, GATA5, SFRP1, ADAM23, JPH3, SFRP2, APC, MGMT, 11112, BNIP3, FOXE1, SYNE1, S0X17, PHACTR3 and JAM3, wherein detection of the epigenetic change is indicative of a predisposition to, or the incidence of, cancer. Also described are pharmacogenetic methods for determining suitable treatment regimens for cancer and methods for treating cancer patients, based around selection of the patients according to the methods of the invention. The present invention is also concerned with improved methods of collecting, processing and analyzing samples, in particular body fluid samples. These methods may be useful in diagnosing, staging or otherwise characterizing various diseases. The invention also relates to methods for identifying, diagnosing, staging or otherwise characterizing cancers, in particular gastrointestinal cancers such as colorectal cancers, gastric cancers and oesophageal cancers. The methods of the invention relate, inter alia, to isolating and analyzing the human DNA component from faecal samples and blood-based samples.06-10-2010
20100297618METHODS FOR DETERMINING A PROGNOSIS OF COLORECTAL CANCER - The invention provides methods for determining a prognosis of colorectal cancer in an individual comprising determining an A-type lamin status of an individual and using the A-type lamin status to determine the prognosis of the colorectal cancer, and more particularly for predicting outcomes of colorectal cancer in the individual such as the survival or mortality of the individual or the likelihood of recurrence of the colorectal cancer. Kits for use in carrying out these methods are also provided.11-25-2010