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Manoj Kumar Singh

Manoj Kumar Singh, Gurgaon IN

Patent application numberDescriptionPublished
20110082458Dynamic External Fixator And Methods For Use - An external fixation system and method for realigning, compressing or distracting broken bones has a planar ring element with an adjustable device having a body releasably mounted on the ring element. The adjustable device includes a first member for movement in a direction generally perpendicular to the ring element. A second member is pivotally connected to the first member for angular movement with respect to the ring. A third member is mounted on the second member for movement in a direction parallel to the second member and with respect to a circumference of the planar ring element. The method includes providing an external fixation system and inserting a k-wire through a first piece of bone and affixing the k-wire or half pin to the ring element. Then inserting a second k-wire or half pin through a second piece of bone and affixing the k-wire or half pin to an adjustable device. The pieces of bone are realigned, compressed or distracted by adjusting at least one of a first and second adjustable member forming the device.04-07-2011

Manoj Kumar Singh, Ahmedabad IN

Patent application numberDescriptionPublished
20090247765PROCESS FOR PREPARING PURE ANASTROZOLE - The present invention discloses two new related substances (6) and (7) of Anastrozole synthesis from Q. A. Salt (5) as in Scheme—1 and purification procedures to get Anastrozole (1) free from (6) and (7).10-01-2009
20100190997Process for the Preparation of Letrozole - The present invention relates to the process for the preparation of Letrozole free from its regioisomer (7) and other impurities by selective extraction of desired intermediate (3) using suitable solvent and mixture of solvents.07-29-2010
20110065927PROCESS FOR PREPARING PURE ANASTROZOLE - The present invention discloses two new related substances (6) and (7) of Anastrozole synthesis from Q.A. Salt (5) as in Scheme-1 and purification procedures to get Anastrozole (1) free from (6) and (7).03-17-2011

Patent applications by Manoj Kumar Singh, Ahmedabad IN

Manoj Kumar Singh, Gujarat IN

Patent application numberDescriptionPublished
20090221837Process for the Preparation of Pure Anastrozole - The present invention relates to the improved process for the preparation of Anastrozole free from the impurities arising due to impure 3,5-bis-(1-cyano-1-methylethyl)benzylbromide (2) and other related impurities resulting from incomplete/over-reaction of 2,2-(5-methyl-1,3-phenylene)-bis(2-methylpropionitrile (I).09-03-2009

Manoj Kumar Singh, Ghaziabad IN

Patent application numberDescriptionPublished
20090318661A BIOCOMPATIBLE, NON-BIODEGRADABLE, NON-TOXIC POLYMER USEFUL FOR NANOPARTICLE PHARMACEUTICAL COMPOSITIONS - The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidone (VP), N-Isopropylacrylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds.12-24-2009

Manoj Kumar Singh, Noida IN

Patent application numberDescriptionPublished
20080300408Process for Preparing a Pure Polymorphic Form of 3-Pyridyl-1-Hydroxyethylidine-1, 1-Bisphosphonic Acid Sodium Salt - This process in general relates to the novel process for preparing polymorphic forms of 3-pyridyl-1-hydroxyethylidine-1,1-bisphosphonic acid sodium salt (Risedronate Sodium) in particular risedronate Form A and B employing a solvent system in an appropriate ratio. An improved process for preparation of risedronic acid is also disclosed in the present invention.12-04-2008
20090312551Process for producing biphosphonic acids and forms thereof - Disclosed herein is a process for producing bisphosphonic acids and salts thereof. The process comprising reacting a carboxylic acid of Formula [I] with phosphorous acid and halophosphorus compound in the presence of a solvent selected from aliphatic hydrocarbon or water miscible cyclic ether. Further, the present invention also provides novel forms of bisphosphonic acids and process for preparation thereof.12-17-2009

Manoj Kumar Singh, Uttar Pradesh IN

Patent application numberDescriptionPublished
20080293682Novel Betulinic Acid Derivatives - The invention relates to novel betulinic acid derivatives of formula (I), wherein R is C(═CH11-27-2008

Manoj Kumar Singh, Harayana IN

Patent application numberDescriptionPublished
20120041439EXTERNAL FIXATOR SYSTEM - An external fixator system comprising at least two fixation plates which are arranged at a distance to each another, at least one adjustable length having a first end region and a second end region which are in connection with the fixation plates and at least one actuation unit to adjust the length of the strut in order to adjust the distance and/or orientation between the fixation plates. The actuation unit is in a fixed connection with at least one of the fixation plates as well as with at least one of the end regions of the respective strut in order to connect the strut with the fixation plate. The actuation unit comprises a feedback unit which provides the user with a feedback concerning the degree of the actuation.02-16-2012