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Mannion
Graham John Mannion, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20090125450 | METHOD AND SYSTEM FOR MEASURING INVESTMENT VOLATILITY AND/OR INVESTMENT PERFORMANCE - The present invention relates to a method and system for measuring investment volatility (e.g., total portfolio volatility of individuals) and/or investment performance (e.g., total portfolio performance of individuals). In one example (which example is intended to be illustrative and not restrictive), the method and system may be used for measuring investment volatility and/or investment performance of personal pension portfolios. In another example (which example is intended to be illustrative and not restrictive), the method and system may provide for measuring volatility of an investment portfolio held by an investor, comprising: providing first information indicating volatility of the investment portfolio over one or more predetermined periods of time; and providing second information indicating volatility of investment portfolios of the investor's peer group (e.g., on average) over the predetermined period(s) of time. | 05-14-2009 |
James C. Mannion, Plainsboro, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100035998 | COMBINATION S-NITROSOTHIOL PHARMACEUTICAL PRODUCTS FOR RESTORING NORMAL BREATHING RHYTHMS - The present invention is directed to a method of treating a lack of normal breathing control including the treatment of apnea and hypoventilation associated with sleep, obesity, certain medicines and other medical conditions. In an aspect, the invention is directed to treating disordered control of breathing by administering an composition comprising a combination of two or more compounds, at least one of which treats lack of normal breathing. In one aspect, a compound is an S-nitrosylating agent. | 02-11-2010 |
| 20100105685 | S-Nitrosothiol Compounds and Related Derivatives - The present invention is directed to a method of treating a lack of normal breathing control including the treatment of apnea and hypoventilation associated with sleep, obesity, certain medicines and other medical conditions. In an aspect, the invention is directed to treating disordered control of breathing by administering an composition comprising a single compound which treats lack of normal breathing. In another aspect, the invention is directed to treating disordered control of breathing by administering an composition comprising a combination of two or more compounds, at least one of which treats lack of normal breathing. In an aspect, a compound is an S-nitrosylating agent. | 04-29-2010 |
| 20110224269 | Analgesic Compounds, Compositions, and Uses Thereof - The invention relates to compounds, compositions, and methods for diminishing pain in a subject in need thereof comprising administering the compounds and compositions herein described. | 09-15-2011 |
John T. Mannion, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110227558 | NANOFLUIDIC CHANNELS WITH INTEGRATED CHARGE SENSORS AND METHODS BASED THEREON - An electrical detector is provided that comprises a nanofluidic channel with an integrated nanoscale charge sensor. The charge sensor can be an unfunctionalized nanowire, nanotube, transistor or capacitor and can be of carbon, silicon, carbon/silicon or other semiconducting material. The nanofluidic channel depth is on the order of the Debye screening length. Methods are also provided for detecting charged molecules or biological or chemical species with the electrical detector. Charged molecules or species in solution are driven through the nanofluidic channel of the electrical detector and contact the charge sensor, thereby producing a detectable signal. Methods are also provided for detecting a local solution potential of interest. A solution flowing through the nanofluidic channel of the electrical detector contacts the charge sensor, thereby producing a detectable local solution potential signal. | 09-22-2011 |
Leslie Mannion, Wake Forest, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090138435 | TECHNIQUES FOR SEARCHING AND PRESENTING SEARCH RESULTS - Techniques for searching and presenting search results to a user are provided. A search is decomposed into sub search combinations. Logical operator ordering is maintained within each sub search combination and each sub search combination is processed to acquire a waterfall count for the resulting answer set associated with processing that sub search combination. The sub search combinations and their waterfall counts are then presented to the user for visual inspection and analysis. | 05-28-2009 |
Leslie Mannion, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100280877 | TECHNIQUES FOR PRODUCT AFFINITY ANALYSIS - Techniques for Product Affinity Analysis are presented. A user interacts with a tool to supply user-defined criteria. The criteria are used to automatically generate code that processes against a data store to collect results that conform to conditions defined by the criteria. The results are used to automatically populate a Product Affinity Analysis chart or grid for the user to view and in some cases dynamically interact with. | 11-04-2010 |
Leslie J. Mannion, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120078941 | QUERY ENHANCEMENT APPARATUS, METHODS, AND SYSTEMS - Apparatus, systems, and methods may operate to receive user-specified input data from a user input device as a segment query that includes a plurality of criteria, and to store individual counts and at least one additional count in a storage medium. The individual counts are derived from processing the segment query as a corresponding plurality of queries associated with each of the criteria, and the at least one additional count comprises an intersection of at least two of the criteria, regardless of whether the user-specified input data includes an intersection operation. Other apparatus, systems, and methods are disclosed. | 03-29-2012 |
Michael Mannion, Cuthbert CA
| Patent application number | Description | Published |
|---|---|---|
| 20100249145 | Inhibitors of VEGF Receptor and HGF Receptor Signaling - The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions | 09-30-2010 |
Michael Mannion, Montreal CA
| Patent application number | Description | Published |
|---|---|---|
| 20090264440 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY - This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. | 10-22-2009 |
| 20090286984 | Processes and intermediates for preparing fused heterocyclic kinase inhibitors - This invention relates to processes and intermediates for manufacturing fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, and to processes and intermediates for preparing intermediates that are useful in the manufacture of fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, particularly at an industrial level. | 11-19-2009 |
| 20100279983 | NOVEL INHIBITORS OF BETA-LACTAMASE - This invention provides novel β-lactamase inhibitors of the aryl- and heteroarylsulfonamidomethylphosphonate monoester class having nitrogen-based cations or quarternary ammonium groups. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazidime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases. Formula (I) or pharmaceutically acceptable salt thereof. | 11-04-2010 |
| 20100317625 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE - This invention provides novel β-lactamase inhibitors of the aryl- and heteroaryl-sulfonamidomethylphosphonate monoester class. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazimdime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases. | 12-16-2010 |
| 20110077240 | INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY - This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions. | 03-31-2011 |
| 20110098293 | Inhibitors of Protein Tyrosine Kinase Activity - This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions. | 04-28-2011 |
| 20110257100 | Inhibitors of Protein Tyrosine Kinase Activity - This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and ophthalmic diseases, disorders and conditions. | 10-20-2011 |
Paul Mannion, Corrandulla IE
| Patent application number | Description | Published |
|---|---|---|
| 20090076416 | Guidewire with Adjustable Core - A movable-core guidewire including a proximal portion and a distal portion. The proximal portion includes a proximal hollow tube. The distal portion includes a coil coupled to the proximal hollow tube and an elastomeric distal tube disposed within the coil. A core wire is disposed within the hypotube. The core wire is movable between a distal position wherein a portion of the core wire is disposed in the distal tube and a proximal portion wherein the core wire is removed from the distal tube. A method is also disclosed for advancing the guidewire to the treatment site. | 03-19-2009 |
Richard O. Mannion, Furlong, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090081290 | TAMPER RESISTANT DOSAGE FORMS - The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof. | 03-26-2009 |
Richard Owen Mannion, Mount Arlington, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100076084 | Method of Treating Metabolic Disorders, Especially Diabetes, or a Disease or Condition Associated with Diabetes - The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (I) | 03-25-2010 |
Robert Mannion, Danbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100058691 | CELLULAR PVC SIDING, TRIM, AND ARCHITECTURAL ASSEMBLIES - Cellular PVC siding, trim, and architectural assemblies are provided which use cellular PVC as an exterior building material due to its stable weatherproof qualities, but which is combined with a substrate to improve the handling and usability of the cellular PVC material. Embodiments of the invention include modular exterior siding assemblies, trim board assemblies, corner trim assemblies, and cylindrical trim assemblies. | 03-11-2010 |