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Mann, MD
David Mann, Gaithersburg, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090202039 | Methods for Sterilizing Biological Materials Containing Non-Aqueous Solvents - Methods are disclosed for sterilizing biological materials to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, | 08-13-2009 |
| 20090214382 | Methods of sterilizing biological mixtures using alpha-keto acids - Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacterial (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible. These methods involve the use of alpha-keto acids in methods of sterilizing biological materials with irradiation. | 08-27-2009 |
David M. Mann, Gaithersburg, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110091353 | Methods for Sterilizing Tissue - Methods are disclosed for sterilizing tissue to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria, (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing one or more tissues with irradiation. | 04-21-2011 |
| 20110154516 | HUMAN FACTOR IX VARIANTS WITH AN EXTENDED HALF LIFE - Factor IX variants are described with an increase in the number of glycosylation sites. The Factor IX variants have an increased half life and/or recovery. | 06-23-2011 |
Dean L. Mann, Rockville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090311214 | COMPOSITIONS AND METHODS FOR THE INNATE IMMUNE RESPONSE PATHWAY - Autoimmune diseases are the consequence of complex interactions between a mosaic of host genetic factors and etiologic elements. Celiac disease (CD) is an autoimmune disease prevalent in 1% of the general population, but is unique on two accounts; a) the majority (90%) of individuals with CD have the HLA class II DQ2 allele, the others HLA-DQ8 and b) the etiologic agent is gluten proteins from wheat and related prolamins in barley and rye. The disease process is generally considered to be mediated by T cells that recognize HLA-DQ2 specific peptide sequences in gluten. There is currently no therapeutic treatment for CD. To this end, the inventors have identified a novel therapeutic target for CD and innate immune pathways in other inflammatory conditions. | 12-17-2009 |
Dean Lemar Mann, Rockville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100266534 | Human Lymphocyte Vaccine Adjuvant - The present invention relates to an adjuvant derived from human lymphocytes. The adjuvant can be used in combination with traditional vaccines or cancer immunotherapy, to enhance the response of the patient's immune system to the vaccine or other immunotherapeutic agent. The adjuvant is derived from the supernatant collected from cultured activated lymphocytes. | 10-21-2010 |
James W. Mann, Elkton, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090187197 | Knit PTFE Articles and Mesh - Disclosed is a knitted article, and a method of producing such an article, having at least one PTFE fiber with oriented fibrils forming multiple fiber cross-over points wherein PTFE fiber is self-bonded in at least one of the cross-over points. | 07-23-2009 |
| 20090206624 | Cantilevered storage unit mount for vehicles - Storage unit mounting apparatus removably and lockably attachable to a vehicle is provided. The apparatus includes a single, cantilevered support member removably and irrotationally attachable at its proximal end to the vehicle, the distal end of the support member supporting a receiver having integral mounting means to which the storage unit is attachable. The apparatus is especially suited for vehicles such as motorcycles, all-terrain-vehicles (ATVs), bicycles and the like. | 08-20-2009 |
James William Mann, Elkton, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090198219 | Catheter Assembly - Novel catheter constructions comprising thin covering or wrapping materials such as polymer films. A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. Moreover, polymer film can be used in combination with one or more elements to produce novel catheter constructions. | 08-06-2009 |
| 20100049123 | Catheter balloons with integrated non-distensible seals - A catheter balloon with integral non-distending regions having a plurality of layers which wind around the balloon material and overlap to form an angle of between 45 and 90 degrees relative to each other upon inflation, and methods of making the non-distending regions are provided. | 02-25-2010 |