Manli
Manli Shen, Lexington, KY US
Patent application number | Description | Published |
---|---|---|
20140275222 | ANTISENSE OLIGONUCLEOTIDE MODULATORS OF SEROTONIN RECEPTOR 2C AND USES THEREOF - The present invention provides, among other things, oligonucleotide modulators of human 5′-HT2C receptor (HTR2C) and improved methods and composition for treating HTR2C-related diseases, disorders or conditions based on such modulators. In particular, oligonucleotides modulators according to the invention target specific regions in the Exon V/Intron V junction of the human HTR2C pre-mRNA and drive expression of HTR2C Vb splice isoform, leading to increased generation of non-edited strong HTR2C receptor and enhanced serotonin receptor activity. | 09-18-2014 |
Manli Wong, Guangdong CN
Patent application number | Description | Published |
---|---|---|
20120056462 | MECHANICAL STRETCHING DEVICE FOR MULTIFUNCTIONAL CONVERTIBLE SOFA - The invention relates to a mechanical stretching device for a multifunctional convertible sofa, which is mainly applied to a convertible sofa, and is a furniture component. The mechanical stretching device includes a first foot lever, a second foot lever, a third foot lever, a fourth foot lever, a side plate, a first connecting rod, a second connecting rod, a third connecting rod, a fourth connecting rod, a fifth connecting rod, a sixth connecting rod, a first support member, a second support member, a linkage member, a seahorse member, a rotating shaft transmission member, a spring, and a bottom connecting rod. A first limiting surface and a second limiting surface are disposed on the second foot lever, a third limiting surface is disposed on the fourth foot lever, a fourth limiting surface and a fifth limiting surface are disposed on the side plate, a sixth limiting surface and a seventh limiting surface are disposed on the second connecting rod, an eighth limiting surface is disposed on the sixth connecting rod, a ninth limiting surface is disposed on the first support member, and a tenth limiting surface is disposed on the linkage member. The structure is reasonably designed, the length increased by unfolding is substantially the same as the length reduced by folding, a back is loose by about 3 mm, and a product subsides by about 2 mm. | 03-08-2012 |
Manli Zhu, New City, NY US
Patent application number | Description | Published |
---|---|---|
20140081631 | Wearable Communication System With Noise Cancellation - A method and a wearable communication system for personal face-to-face and wireless communications in high noise environments are provided. A noise cancellation device (NCD) operably coupled to a wireless coupling device (WCD) includes a speech acquisition unit, an audio signal processing unit, one or more loudspeakers, and a communication module. The NCD receives voice vibrations from user speech via a contact microphone and a second microphone and converts the voice vibrations into an audio signal. The NCD processes the audio signal to remove noise signals and enhance a speech signal contained in the audio signal. A loudspeaker emits the speech signal during face-to-face communication. The NCD transmits the speech signal to a communication device via the WCD and receives an external speech signal from the communication device during wireless communication. With the NCD, the signal intelligibility and signal-to-noise ratio can be improved, for example, from −10 dB to 20 dB. | 03-20-2014 |