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Mani, US

Ajay Mani, Woodinville, WA US

Patent application numberDescriptionPublished
20120102481Coordinated Upgrades In Distributed Systems - A distributed application may be updated by using information provided by the application to determine grouping, sequencing, and whether or not to advance an update sequence. The application may provide input to an update sequence, and may cause the update sequence to repair one or more replicas prior to updating. The update mechanism may be used to change the distributed application topology as well as make changes to the application executable code, application configuration, quest operating system, virtual machine, and host systems, among others. In some cases, the distributed application may use a quorum to determine which version is current, and the quorum may change during the update process.04-26-2012

Ayyakannu Mani, Rochester Hills, MI US

Patent application numberDescriptionPublished
20100218705PALLETS - The present invention provides enhanced pallets. The pallets may be aluminum extruded pallets having a plurality of hollow blocks and a plurality of hollow cross members. The blocks and cross members are welded together to form a pallet. The blocks and cross members may have internal wall structures which, form one or more crush cells or crush zones. The crush cells or crush zones deform in a controlled manner on impact to reduce impact damage to the pallets. The pallets have a high load strength supporting capability and allow the pallets to withstand repeated or severe impacts while remaining functional.09-02-2010
20110006554Automobile safety bumper assemlby - A safety automobile bumper assembly includes energy absorbers interposed between a fascia and bumper beam comprised of a strip of deformable material formed with a loop with opposite curved ends deformed by relative movement of the fascia and bumper beam in an impact. Additional curved strip positions are provided by one or more additional loops or by one or more inner webs to increase energy absorbing capacity.01-13-2011
20110115204AUTOMOTIVE KNEE BOLSTER INSTALLATION AND METHOD OF CONSTRUCTION - A knee bolster installation for an automotive vehicle includes a bridge plate extending across a space receiving a steering column in front of the driver's knee or a glove box in front of a passenger's knees and having a knee impact absorber structure attached behind each end of the bridge plate. Each knee impact absorber structure has diverging front and back walls having a curved top wall and a curved generally horizontal intermediate web extending between the front and back walls, and a curved bottom wall connecting the lower end of front and back walls together. A generally vertical stabilizer web connects the top wall and intermediate web together to restrain bulging when crushed to avoid horizontal collapse thereof during deformation. Offset openings in each of the top wall, intermediate web, and bottom wall form wider curved strips at the inside adjacent the steering column space so that the front of the outside ends of the knee installation absorber structures are inclined away from the steering column space when deformed by knee impact. The knee installation absorber structures are either extruded and the openings thereafter cut into the top wall, intermediate web and bottom wall, or formed from a flat strip of material into which openings are cut prior to forming the strip.05-19-2011
20110215614Lightweight cross-car beam and method of constructing a structural member - A cross car beam or other elongated structural member including a series of walled open ended sections fixed end to end in a linear array by having ends joined to respective sides of a series of interposed junction plates. The junction plates may have locator features formed thereon to properly position the respective ends of adjacent sections and to be located in a welding fixture.09-08-2011

Deepa Mani, Stow, OH US

Patent application numberDescriptionPublished
20100069970Orthopedic compression screw - A cannulated compression screw is used as an orthopedic implant and has a threaded distal end with an insertion tip that includes at least one and preferably two, three or four flutes to allow the screw to be self-tapping. Optionally, the screw also includes one or more reverse cutting flutes proximal to the insertion tip. The distal threads are cancellous threads having a generally constant minor diameter and a generally constant major diameter and a generally constant thread pitch. An intermediate portion of the screw is non-threaded and the proximal end includes a compression wedge or taper that has at least one, and preferably two to five flutes that terminate before the top of the screw. The proximal end further includes a radiused bevel to the terminal surface that includes a hexagonal torque driving recess. The diameter of the non-threaded shaft section is constant distal from the compression wedge to the distal tip where it defines the minor diameter of the threaded portion. The screw optionally includes a tapered insertion tip.03-18-2010

Ganesh Mani, Pittsburgh, PA US

Patent application numberDescriptionPublished
20080222041Methods and Systems for Electronic Agency in Performance of Services - A computer implemented method for a principal to electronically establish and use an agent. The method comprising the steps of: the principal identifying a service requirement, the principal entering a communication medium to interact with a potential agent, the principal submitting an electronic request for service, the principal and the agent negotiating terms, establishing an electronic power of attorney between the principal and the agent, the agent performing the requested service; and the principal paying the agent.09-11-2008

Krishnamurthy Mani, Basking Ridge, NJ US

Patent application numberDescriptionPublished
20090178928Process for Desalting Glycerol Solutions and Recovery of Chemicals - Processes for desalting glycerol-rich solutions or process streams using electrodialysis are provided. The glycerol-rich process streams are typically byproducts from the production of biodiesel. Following electrodialysis, the resulting aqueous salt solution is placed in a water splitting cell to recover the acid and base components of the salt. These acid and base components, in turn, can be reused in other processes, such as biodiesel production.07-16-2009

Kumar Mani, Maywood, NJ US

Patent application numberDescriptionPublished
20090204597SYSTEM AND METHOD FOR PREFERRED SERVICES IN NOMADIC ENVIRONMENTS - A method of locating preferred services includes searching an augmented spatial index, which is based on a user's determined preferred services. Additionally, the method includes indicating a location of a currently-sought preferred service.08-13-2009
20100228529SYSTEM AND METHODS FOR REQUIREMENTS MANAGEMENT AND MODELING IN COMPLEX SYSTEMS INTEGRATION - A method and product for modeling and managing requirements in a complex integrated system, which comprises creating a set of requirements which can be implemented within all the components of the complex integrated system. Each requirement may be characterized as a point on the circumference of a circle, the characterization being an assignment of a requirement type. This type determines which circle the point will be located on, assigning a unique immutable numerical value to each requirement that determines in which order the point is placed on the previously determined circle.09-09-2010

Mori Mani, St. Louis, MO US

Patent application numberDescriptionPublished
20080279041FLUIDIC MIXER WITH CONTROLLABLE MIXING - In one embodiment of the disclosure, a fluid mixing device comprises a flow duct, with a wall having an inner surface defining a fluid flow path for a primary flow, and at least one deployable and retractable projection. The projection is adapted to controllably generate at least one secondary flow adjacent the inner surface. In other embodiments, methods are provided of controllably mixing at least one fluid within a fluid mixing device.11-13-2008

Moriaza Mani, St. Louis, MO US

Patent application numberDescriptionPublished
20120089382DYNAMIC LOAD BALANCING FOR ADAPTIVE MESHES - A method for dynamic load balancing of a mesh, wherein the mesh is partitioned to find a solution using a plurality of processors, and wherein the partitions have become unbalanced. The present method allows large portions of the mesh to continue to progress towards a solution by only repartitioning a small percentage of the overall mesh. This is done by stripping cells along the partition interfaces using a marching method to form a free-cell region, repartitioning the free-cell region, and joining the repartitioned portions of the free-cell region with the remaining cells in a manner that will increase the efficiency of the solver.04-12-2012

Mortaza Mani, St. Louis, MO US

Patent application numberDescriptionPublished
20100145668METHOD FOR DYNAMIC REPARTITIONING IN ADAPTIVE MESH PROCESSING - A method for dynamic repartitioning of a mesh, wherein the mesh is partitioned to find a solution using a plurality of processors, and wherein the partitions have become unbalanced. The present method allows large portions of the mesh to continue to progress towards a solution by only repartitioning a small percentage of the overall mesh. This is done by stripping cells along the partition interfaces using a marching method to form a free-cell region, repartitioning the free-cell region, and joining the repartitioned portions of the free-cell region with the remaining cells in a manner that will increase the efficiency of the solver.06-10-2010

Nagraj Mani, Natick, MA US

Patent application numberDescriptionPublished
20100172866Combination Therapy for the Treatment of HCV Infection - The present invention relates to therapeutic combinations comprising a protease inhibitor and a polymerase inhibitor for the treatment of HCV. The present invention also relates to therapeutic combinations comprising VX-950 and a polymerase inhibitor. Also within the scope of the invention are methods using the therapeutic combinations of the present invention for treating HCV infection or alleviating one or more symptoms thereof in a patient. The present invention also provides kits comprising the combinations of the present invention.07-08-2010

Narasimhan Mani, Port Jefferson, NY US

Patent application numberDescriptionPublished
20080242728PHENOLIC ACID SALTS OF GABAPENTIN IN SOLID DOSAGE FORMS AND METHODS OF USE - The present invention relates to pharmaceutical compositions of gabapentin tannate in solid dosage form, processes for production of those compositions and methods of use of those compositions. Tannate salts of active pharmaceutical ingredients are used in sustained release applications and to improve certain organoleptic properties such as taste. The process may utilize either natural or synthetic tannic acid.10-02-2008
20110288079Tannate Compositions, Methods of Making and Methods of Use - Tannate compositions containing active pharmaceutical ingredients to be used for treating nausea, vomiting, pain, convulsions, and insomnia and manufacturing processes for preparing the tannate compositions.11-24-2011

Patent applications by Narasimhan Mani, Port Jefferson, NY US

Neel K. Mani, Stow, OH US

Patent application numberDescriptionPublished
20100175801TIRE AND WHEEL RIM ASSEMBLY - A tire and wheel rim assembly comprising a wheel rim having flange portions and ledge portions, wherein each ledge portion has at least one circumferentially continuous groove with a circumferentially continuous surface. The assembly further includes a tire having bead regions comprising a ledge portion having a toe, a heel, and at least one circumferentially continuous rib with a peak, wherein the at least one circumferentially continuous rib of the tire extends radially into the at least one circumferentially continuous groove of the wheel rim.07-15-2010
20100269970TIRE WITH CIRCUMFERENTIAL GROOVES IN THE BEAD REGION - A tire comprising a circumferential tread, a circumferential tread, at least one circumferential belt, at least one carcass ply, a pair of sidewalls, and a pair of bead portions. Each of the bead portions comprising a bead core, a bead filler, a toe region, a heel region, a ledge region, and a flange region. The ledge region is provided between the toe region and the heel region, wherein the ledge region comprises at least one circumferentially continuous groove. The flange region each extending circumferentially about the tire, the flange region provided radially above the ledge region, wherein the flange region comprises at least one circumferentially continuous groove.10-28-2010

Nikhil Mani, Billerica, MA US

Patent application numberDescriptionPublished
20100109181CONTROLLING DELIVERY OF POLYMER MATERIAL IN A SEQUENTIAL INJECTION MOLDING PROCESS - Method and apparatus for controlling the delivery of polymer material in a sequential injection molding process. In one embodiment, the method provides: delivering a first shot of a first material simultaneously to a plurality of mold cavities; independently sensing for each cavity a property that is indicative of a volume or flow of material that is delivered to the corresponding cavity during the step of delivering the first shot; independently stopping the step of delivering the first shot to one or more cavities according to a program that uses as a variable a signal indicative of the property sensed for the corresponding cavity during delivery of the first shot; and delivering a second shot of a second material simultaneously to the cavities subsequent to the step of stopping the step of delivering the first shot.05-06-2010
20100187720TAKE OUT AND COOLING SYSTEM AND METHOD - A take-out and cooling method and apparatus conveys molded plastic articles from a molding machine to and through a cooling station and preferably includes a take-out apparatus that has a main support, a conveyor carried by the main support for movement in an endless path, a cam adjacent to the support, a plurality of arms carried by the conveyor for movement with the conveyor along the endless path and including a follower responsive to the contour of the cam to vary the position of the arms relative to the support, and at least one holder carried by each arm. Each holder is adapted to receive and carry at least one molded article to facilitate in conveying the molded articles and is flexible and resilient to permit relative movement of at least a portion of the holder relative to its associated arm.07-29-2010
20110212204CONTROLLING DELIVERY OF POLYMER MATERIAL IN A SEQUENTIAL INJECTION MOLDING PROCESS - Method and apparatus for controlling the delivery of polymer material in a sequential injection molding process. In one embodiment, the method provides: delivering a first shot of a first material simultaneously to a plurality of mold cavities; independently sensing for each cavity a property that is indicative of a volume or flow of material that is delivered to the corresponding cavity during the step of delivering the first shot; independently stopping the step of delivering the first shot to one or more cavities according to a program that uses as a variable a signal indicative of the property sensed for the corresponding cavity during delivery of the first shot; and delivering a second shot of a second material simultaneously to the cavities subsequent to the step of stopping the step of delivering the first shot.09-01-2011

Patent applications by Nikhil Mani, Billerica, MA US

Ram Shankar Mani, Ann Arbor, MI US

Patent application numberDescriptionPublished
20100227910GENE FUSION TARGETED THERAPY - The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to recurrent gene fusions as clinical targets for prostate cancer.09-09-2010
20110207675GENE FUSION TARGETED THERAPY - The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to recurrent gene fusions as clinical targets for prostate cancer.08-25-2011

Sendurai Mani, Cambridge, MA US

Patent application numberDescriptionPublished
20100260827Methods of diagnosing, preventing and treating cancer metastasis - The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis.10-14-2010

Senthil Kumar Kumarasamy Mani US

Patent application numberDescriptionPublished
20080209539System and method for preventing service oriented denial of service attacks - A method, system, and computer program product for preventing network service attacks, including processing a message to validate the message for message version and syntax via a security firewall; canonicalizing the message and extracting a message header and body via a converter; converting the body into a Patricia Trie via the converter; and validating the header and the converted body for security via a comparator.08-28-2008

Sridhar Mani, Riverdale, NY US

Patent application numberDescriptionPublished
20110105522KETOCONAZOLE-DERIVATIVE ANTAGONIST OF HUMAN PREGNANE X RECEPTOR AND USES THEREOF - The application discloses ketoconazole derivatives that are antagonists of the human pregnane X receptor (PXR), methods of preparing the derivatives, uses of the derivatives with drug therapy, and methods of inhibiting tumor cell proliferation and multidrug resistance using inhibitors of PXR.05-05-2011
20110251189HYPOXIA TARGETED COMPOUNDS FOR CANCER DIAGNOSIS AND THERAPY - The present invention generally relates to oxazine derivative compounds and related compositions and methods for inducing hypoxic tumor cell death, treating cancer and locating a hypoxic tumor in a subject.10-13-2011

Sundararaj Mani, Waukesha, WI US

Patent application numberDescriptionPublished
20110276338AUTOMATED WORKFLOW ENGINE IN A DELIVERY OF HEALTHCARE - Systems and methods for tracking the real-time progress of a medical workflow are provided. In one embodiment, a method includes receiving in a data processing system locations of a plurality of objects from a location system and determining in near real time whether the real-time locations indicate that a predetermined workflow has progressed from a first stage to a second stage using the data processing system.11-10-2011

Suresh Mani, Ann Arbor, MI US

Patent application numberDescriptionPublished
20080248393TIN IN AN ACTIVE SUPPORT MATRIX - An anode material made from nanoparticles, said anode material including a homogeneous mixture of lithium-alloying nanoparticles with active support matrix nanoparticles, is provided. The active support matrix nanoparticle is a compound that participates in the conversion reaction of the lithium battery. The compound is preferably a transition metal compound, with said compound including a nitride, carbide, oxide or combination thereof.10-09-2008
20090170002ALKALI METAL TITANATES, AND ELECTRODES AND BATTERIES BASED ON THE SAME - Disclosed is a lithium titanate material, which may include an additive, and its use as an electrode in a battery. Specifically disclosed is a lithium titanate based material, with primary particle size larger than 100 nm, having very good high rate charge and discharge capabilities when incorporated into a lithium battery.07-02-2009
20090179181SILICON BASED COMPOSITE MATERIAL - A composite material having utility as an anode for lithium ion batteries comprises silicon, a transition metal, a ceramic and an electrically conductive diluent such as carbon. In particular instances, the ceramic is electrically conductive, and may comprise vanadium carbide or tungsten carbide. The transition metal may, in some instances, comprise iron. The material may be fabricated by grinding together a starting mixture of the components, and grinding may be accomplished in a high impact ball milling process, and the grinding step may cause partial alloying of the silicon with the metal and/or carbon. Further disclosed is a method for making the material as well as electrodes which incorporate the material.07-16-2009

Patent applications by Suresh Mani, Ann Arbor, MI US

Vanita Mani, Clifton Park, NY US

Patent application numberDescriptionPublished
20090041198HIGHLY COLLIMATED AND TEMPORALLY VARIABLE X-RAY BEAMS - Systems and methods for highly collimated and temporally variable X-ray beams. Disclosed herein is a system for producing a collimated X-ray beam, the system including one or more distributed electron sources configured to produce electron beams, one or more X-ray production targets configured to receive the electron beams and to generate X-ray beams at X-ray focal spots, X-ray optics configured to collect the X-ray beams from the X-ray focal spots, wherein the X-rays optics are configured to focus the X-ray beams to a single virtual focal spot, and an X-ray collimator configured to collimate the X-ray beams from the virtual focal spot to generate the collimated X-ray beam.02-12-2009
20100283033CARBIDE NANOSTRUCTURES AND METHODS FOR MAKING SAME - A structure includes a substrate and a metallized carbon nano-structure extending from a portion of the substrate. In a method of making a metallized carbon nanostructure, at least one carbon structure formed on a substrate is placed in a furnace. A metallic vapor is applied to the carbon nanostructure at a preselected temperature for a preselected period of time so that a metallized nanostructure11-11-2010
20110206187HIGH FLUX PHOTON BEAMS USING OPTIC DEVICES - A system for producing at least one high flux photon beam is provided. The system includes two or more photon sources configured to produce photon beams, and at least one first stage optic device coupled to at least one of the photon sources and providing at least one focused photon beam through total internal reflection, wherein at least one of the photon beams and the focused photon beams are combined at a virtual focal spot.08-25-2011

Patent applications by Vanita Mani, Clifton Park, NY US

Vivek Mani, Chicago, IL US

Patent application numberDescriptionPublished
20090164681Portable Module Interface with Timeout Prevention by Dummy Blocks - Methods and systems for working around the timeout limitations of physical interface standards for detachable modules. By use of dummy data blocks to keep the bus active, the bus timeout requirements (in either direction) can be spoofed, to thereby permit more complex processing operations to be performed, which otherwise might not fit reliably within the timeout period. This permits a memory system to execute applications or process data for a time period that may exceed the bus timeout of a particular specification. A controller in the memory system deasserts the ready signal and holds the bus connecting the computer system in a “busy” state until the memory system is about to timeout. During a write operation, the controller receives dummy data blocks from the computer system before the write bus timeout period expires, causing the bus timeout period to be reset. During a read operation, the controller sends dummy data blocks to the computer system before the read bus timeout period expires, causing the bus timeout period to be reset.06-25-2009