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Manalo, CA

Dante Manalo, Santa Clara, CA US

Patent application numberDescriptionPublished
20100087062HIGH TEMPERATURE BD DEVELOPMENT FOR MEMORY APPLICATIONS - A method and apparatus for depositing organosilicate dielectric layers having good adhesion properties and low dielectric constant. Embodiments are described in which layers are deposited at low temperature and at high temperature. The low temperature layers are generally post-treated, whereas the high temperature layers need no post treating. Adhesion of the layers is promoted by use of an initiation layer.04-08-2010

Jean-Claire L. Manalo, Daly City, CA US

Patent application numberDescriptionPublished
20110071145Raf Modulators And Methods Of Use - The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Raf. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention.03-24-2011

Patent applications by Jean-Claire L. Manalo, Daly City, CA US

Jean-Claire Limun Manalo, Daly City, CA US

Patent application numberDescriptionPublished
20090156576Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases - Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.06-18-2009
20090163471Tropane compounds - A compound according to Formula I or II:06-25-2009
20100130488Pyrazolo-Pyrimidines as Casein Kinase II (CK2) Modulators - A compound according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R05-27-2010
20100249096Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases - Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.09-30-2010
20100298290Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their Use and Manufacture - The invention is directed to Compounds of Formula I:11-25-2010

Jean-Claire Limun Manalo, Dale City, CA US

Patent application numberDescriptionPublished
20090215803Pyrimidinones as Casein Kinase II (CK2) Modulators - A compound having Formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R08-27-2009

Nikita R. Manalo, Santa Clara, CA US

Patent application numberDescriptionPublished
20090087468Semi-Rigid Gel Article For Disinfecting A Surface - The present invention relates to a semi-rigid gel article which contains an antibacterial agent and can be used for disinfecting and/or cleaning a surface. More particularly, the article comprises water, a gelling agent, an antibacterial agent and wherein the article is capable of disinfecting a surface by contacting the surface with the article, rupturing the article by application of pressure and spreading the article on the surface to deliver the antimicrobial agent. The article is suitable to disinfect and/or clean an inanimate or animate surface with or without water.04-02-2009
20090312215Semi-Rigid Gel Cleansing Article and Uses Thereof - The present invention relates to semi-rigid gels, methods of manufacture and uses thereof.12-17-2009