Patent application number | Description | Published |
20090240087 | Process for Producing Optically Active Fluorobenzyl Alcohol - A fluorine-containing benzaldehyde is reacted with an alkyl Grignard reagent to convert it to a magnesium alkoxide of racemic, fluorine-containing, benzyl alcohol, and subsequently the magnesium alkoxide is reacted with phthalic anhydride to obtain a phthalate half ester of racemic, fluorine-containing, benzyl alcohol, and the half ester is optically resolved by optically active 1-phenylethylamine, and then the ester group is hydrolyzed, thereby producing an optically active, fluorine-containing, benzyl alcohol. | 09-24-2009 |
20090250658 | Dehydroxyfluorination Agent - There is provided a novel, useful dehydroxyfluorination agent containing sulfuryl fluoride (SO | 10-08-2009 |
20100267940 | Method for Producing 4-Deoxy-4-Fluoro-D-Glucose Derivative - There is disclosed a method for producing a 4-deoxy-4-fluoro-D-glucose derivative by reacting a D-galactose derivative with either sulfuryl fluoride (SO | 10-21-2010 |
20110015428 | Process for Producing Alpha-Fluoro-Beta-Amino Acids - By reacting a β-hydroxy-α-amino acid with sulfuryl fluoride (SO | 01-20-2011 |
20110034732 | Process for Production of Optically Active Fluoroamine - Disclosed is a process for producing a protected optically active fluoroamine, which comprises the step of reacting an imine-protected optically active hydroxyamine, an oxazolidine-protected optically active hydroxyamine, or a mixture of the imine-protected optically active hydroxyamine and the oxazolidine-protected optically active hydroxyamine, with sulfuryl fluoride (SO | 02-10-2011 |
20110152536 | Process for Production of Alpha-Trifluoromethyl-Beta-Substituted-Beta-Amino Acid - α-Trifluoromethyl-β-substituted-β-amino acids can be produced by allowing α-trifluoromethyl-β-substituted-α,β-unsaturated esters to react with hydroxylamine to convert α-trifluoromethyl-β-substituted-α,β-unsaturated esters into dehydrogenated closed-ring body of α-trifluoromethyl-β-substituted-β-amino acid, and by hydrogenolyzing the dehydrogenated closed-ring body. According to this production process, novel α-trifluoromethyl-β-substituted-β-amino acids which are free amino acids whose functional groups are not protected can be produced, in which β-position substituent is not limited to aromatic ring group or substituted aromatic ring group while the relative stereochemistry of α-position and β-position can be also controlled. | 06-23-2011 |
20110160477 | Process for Producing alpha-Trifluoromethyl-alpha,beta-Unsaturated Ester - An α-trifluoromethyl-α,β-unsaturated ester can be produced by reacting an α-trifluoromethyl-α-hydroxy ester with sulfuryl fluoride (SO | 06-30-2011 |
20110201825 | Method for Producing Fluorosulfuric Acid Ester - Fluorosulfuric acid esters can be produced by reacting alcohols with sulfuryl fluoride (SO | 08-18-2011 |
20110213176 | Process for Producing alpha Substituted Ester - There is provided a process for producing an α-substituted ester by reaction of a fluorosulfuric acid ester of α-hydroxyester with a Grignard reagent in the presence of a zinc catalyst. It is newly found that the reaction for production of α-substituted esters, in which the raw reaction substrate is limited to expensive trifluoromethanesulfonic acid esters, can proceed favorably with the use of fluorosulfuric acid esters suitable for mass-production uses. By the use of the fluorosulfuric acid ester high in optical purity, it is possible to obtain the α-substituted ester with high optical purity upon inversion of the asymmetric carbon configuration. The process of the present invention can solve all of the prior art problems and can be applied for industrial uses. | 09-01-2011 |
20110251403 | Method for Manufacturing Hydroxyl Group Substitution Product - In the present invention, a hydroxyl group substitution product is manufactured by reaction of an alcohol with sulfuryl fluoride (SO | 10-13-2011 |