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Manabu Yasumoto, Saitama JP

Manabu Yasumoto, Saitama JP

Patent application numberDescriptionPublished
20090240087Process for Producing Optically Active Fluorobenzyl Alcohol - A fluorine-containing benzaldehyde is reacted with an alkyl Grignard reagent to convert it to a magnesium alkoxide of racemic, fluorine-containing, benzyl alcohol, and subsequently the magnesium alkoxide is reacted with phthalic anhydride to obtain a phthalate half ester of racemic, fluorine-containing, benzyl alcohol, and the half ester is optically resolved by optically active 1-phenylethylamine, and then the ester group is hydrolyzed, thereby producing an optically active, fluorine-containing, benzyl alcohol.09-24-2009
20090250658Dehydroxyfluorination Agent - There is provided a novel, useful dehydroxyfluorination agent containing sulfuryl fluoride (SO10-08-2009
20100267940Method for Producing 4-Deoxy-4-Fluoro-D-Glucose Derivative - There is disclosed a method for producing a 4-deoxy-4-fluoro-D-glucose derivative by reacting a D-galactose derivative with either sulfuryl fluoride (SO10-21-2010
20110015428Process for Producing Alpha-Fluoro-Beta-Amino Acids - By reacting a β-hydroxy-α-amino acid with sulfuryl fluoride (SO01-20-2011
20110034732Process for Production of Optically Active Fluoroamine - Disclosed is a process for producing a protected optically active fluoroamine, which comprises the step of reacting an imine-protected optically active hydroxyamine, an oxazolidine-protected optically active hydroxyamine, or a mixture of the imine-protected optically active hydroxyamine and the oxazolidine-protected optically active hydroxyamine, with sulfuryl fluoride (SO02-10-2011
20110152536Process for Production of Alpha-Trifluoromethyl-Beta-Substituted-Beta-Amino Acid - α-Trifluoromethyl-β-substituted-β-amino acids can be produced by allowing α-trifluoromethyl-β-substituted-α,β-unsaturated esters to react with hydroxylamine to convert α-trifluoromethyl-β-substituted-α,β-unsaturated esters into dehydrogenated closed-ring body of α-trifluoromethyl-β-substituted-β-amino acid, and by hydrogenolyzing the dehydrogenated closed-ring body. According to this production process, novel α-trifluoromethyl-β-substituted-β-amino acids which are free amino acids whose functional groups are not protected can be produced, in which β-position substituent is not limited to aromatic ring group or substituted aromatic ring group while the relative stereochemistry of α-position and β-position can be also controlled.06-23-2011
20110160477Process for Producing alpha-Trifluoromethyl-alpha,beta-Unsaturated Ester - An α-trifluoromethyl-α,β-unsaturated ester can be produced by reacting an α-trifluoromethyl-α-hydroxy ester with sulfuryl fluoride (SO06-30-2011
20110201825Method for Producing Fluorosulfuric Acid Ester - Fluorosulfuric acid esters can be produced by reacting alcohols with sulfuryl fluoride (SO08-18-2011

Patent applications by Manabu Yasumoto, Saitama JP