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Malakhov

Anton Malakhov, Nizhny Novgorod RU

Patent application numberDescriptionPublished
20120036134PERFORMING CONCURRENT REHASHING OF A HASH TABLE FOR MULTITHREADED APPLICATIONS - In one embodiment, the present invention includes a method for allocating a second number of buckets for a hash table shared concurrently by a plurality of threads, where the second number of buckets are logically mapped onto a corresponding parent one of the first number of buckets, and publishing an updated capacity of the hash table to complete the allocation, without performing any rehashing, such that the rehashing can later be performed in an on-demand, per bucket basis. Other embodiments are described and claimed.02-09-2012

Michael Malakhov, San Francisco, CA US

Patent application numberDescriptionPublished
20110182875NOVEL CLASS OF THERAPEUTIC PROTEIN BASED MOLECULES - The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.07-28-2011

Michael Malakhov, San Diego, CA US

Patent application numberDescriptionPublished
20090098207Technology for the Preparation of Microparticles - Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions.04-16-2009
20090142327Novel Class of Therapeutic Protein Based Molecules - The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.06-04-2009

Michael P. Malakhov, San Francisco, CA US

Patent application numberDescriptionPublished
20110171132Methods, Compounds, and Compositions for Treatment and Prophylaxis in the Respiratory Tract - The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.07-14-2011

Michael P. Malakhov, San Diego, CA US

Patent application numberDescriptionPublished
20100166874Technology for Preparation of Macromolecular Microspheres - Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions.07-01-2010

Vladimir Malakhov, Muenchen DE

Patent application numberDescriptionPublished
20110084230Process for Synthesizing Organoelemental Compounds - The present application discloses a process for preparing a compound of the general formula R04-14-2011

Yefim Malakhov, English Town, NJ US

Patent application numberDescriptionPublished
20110275277Adjustable Bra - The adjustable bra of the present invention includes an adjustment element that permits adjustment of the length of the front, adjustment of the length of the side, and/or adjustment of the length of the back, and/or adjustment of the cup size. The bra comprises a pair of bra cups and a band, the band comprising a front underbust band attached to and underlying the bra cups, a back band, and a pair of length adjustment elements for independently adjusting the length of the band.11-10-2011