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Makarov

Alexander A. Makarov, Breman DE

Patent application numberDescriptionPublished
20110192968Multi-Needle Multi-Parallel Nanospray Ionization Source for Mass Spectrometry - An electrospray ion source for a mass spectrometer includes an electrode comprising at least a first plurality of protrusions protruding from a base, each protrusion of the at least a first plurality of protrusions having a respective tip; a conduit for delivering an analyte-bearing liquid to the electrode; and a voltage source, wherein, in operation of the electrospray ion source, the analyte-bearing liquid is caused to move, in the presence of a gas or air, from the base to each protrusion tip along a respective protrusion exterior so as to form a respective stream of charged particles emitted towards an ion inlet aperture of the mass spectrometer under application of voltage applied to the electrode from the voltage source.08-11-2011

Alexander Alekseevich Makarov, Bremen DE

Patent application numberDescriptionPublished
20100051799MULTI-CHANNEL DETECTION - A mass spectrometer and method of mass spectrometry wherein charged particles in a beam undergo multiple changes of direction. A detection arrangement detects a first portion of the charged particle beam, and provides a first output based upon the intensity of the detected first portion of the charged particle beam. The detection arrangement detects a second portion of the charged particle beam that has travelled a greater path length through the mass spectrometer than the first portion of the charged particle beam, and provides a second output based upon the detected second portion of the charged particle beam. A controller adjusts the parameters of the charged particle beam and/or the detection arrangement, based upon the first output of the detection arrangement, so as to adjust the second output of the detection arrangement.03-04-2010
20100059673Multiple Ion Isolation in Multi-Reflection Systems - This invention relates to a method of operating a charged particle trap in which ions undergo multiple reflections back and forth and/or follow a closed orbit around, usually, a set of electrodes. The invention allows high-performance isolation of multiple ion species for subsequent detection or fragmentation by deflecting ions out of the ion trap according to a timing scheme calculated with reference to the ions' periods of oscillation within the ion trap.03-11-2010
20110147582Multiple Ion Injection in Mass Spectrometry - This invention relates to mass spectrometry that includes ion trapping in at least one of the stages of mass analysis. In particular, although not exclusively, this invention relates to tandem mass spectrometry where precursor ions and fragment ions are analysed. A method of mass spectrometry is provided comprising the sequential steps of: accumulating in an ion store a sample of one type of ions to be analysed; accumulating in the ion store a sample of another type of ions to be analysed; and mass analysing the combined samples of the ions; wherein the method comprises accumulating the sample of the one type of ions and/or the sample of another type of ions to achieve a target number of ions based on the results of a previous measurement of the respective type of ions.06-23-2011

Alexander Alekseevich Makarov, Cheadle Hulme GB

Patent application numberDescriptionPublished
20090179150MASS SPECTROMETER WITH LOOPED ION PATH - A mass spectrometer includes at least one ion selector, at least one collision cell, and an ion path switching device arranged to define a looped ion path around which ions derived from a sample may be sent multiple times (without reversal of ion travel) in order to effect a desired number of isolation/fragmentation cycles for MSn analysis. When the desired number of isolation/fragmentation cycles have been completed, the ion path switching device directs the ions to a detector or a separate mass analyzer for acquisition of a mass spectrum.07-16-2009

A. Vadim Makarov, Moscow RU

Patent application numberDescriptionPublished
20110160193New Benzothiazinone Derivatives and Their Use as Antibacterial Agents - The present invention relates to novel benzothiazinone derivatives and their use as antibacterial agents in infectious diseases of mammals (humans and animals) caused by bacteria, especially diseases like tuberculosis (TB) and leprosy caused by mycobacteria. The present invention aims at the generation of new compounds with activity against mycobacteria as potential new tuberculosis drugs to overcome problems concerning resistance and drug intolerance. The solution of the present invention is a compound of formula I06-30-2011

A. Vadim Makarov, Moskow RU

Patent application numberDescriptionPublished
20090239851Benzothiazinone Derivatives and their Use as Antibacterial Agents - The present invention relates to novel benzothiazin derivatives and their use as antibacterial agents in infectious diseases of mammals (humans and animals) caused by bacteria, especially diseases like tuberculosis (TB) and leprosy caused by mycobacteria.09-24-2009

Boris Makarov, Bat Yam IL

Patent application numberDescriptionPublished
20100264590SOCCER BOARD GAME - A soccer board game and a method for playing it by first and second contestants is disclosed. The game board included a board comprising a grid of distinctly marked squares with soccer field markings. The soccer field markings include a half line dividing the field into two half fields, a kick-off circle on the half line, two opposite goal boxes located on opposite ends of the field, a five-zone and a sixteen-zone areas adjacent each of the goal boxes. The board game includes at least one die; a ball; and opponent first and second teams of players, each team pertaining to one of the contestants.10-21-2010

Dmitry Makarov, Ansan-Si KR

Patent application numberDescriptionPublished
20090093866Composite Light Source Apparatus for Phototherapy - The present invention provides a composite light source apparatus for phototherapy of skin disease, in which a light beam having the wavelength and optical power suitable for light-beam treatment is provided to a region to be treated (also called a ‘to-be-treated region’) through a light guide by using a composite light source so as to improve efficiency of phototherapy of skin diseases of the body including acne, malignant tumors and the like. According to the composite light source apparatus, uniform optical power can be provided through a combination of a plurality of light sources, the optical power can be provided through selection of light of a wavelength range that a user wants, and light from the light sources can be utilized to the maximum with increased light intensity.04-09-2009

Gennady Grigorievich Makarov, Moscow RU

Patent application numberDescriptionPublished
20110154725AGENT FOR INCREASING THE OCTANE NUMBER OF A GASOLINE AUTOMOBILE FUEL - The invention relates to an agent for increasing the octane number of a gasoline automotive fuel, which agent is a combination of alcohol and a product of reaction between a carbonyl compound and a compound containing at least two hydroxyl groups enabling to form cycles with carbonyl compounds, or is the mixtures of the above mentioned products. In the preferred variant, mono- or oligosaccharides or diatomic, triatomic or polyatomic alcohols are used as the compounds containing at least two hydroxyl groups enabling to form cycles with carbonyl compounds. Pentoses, preferably xylose or arabinose or hexose, substantially glucose, and the mixtures thereof are used as the monosaccharides. Glycols, for example, ethylene glycol are used as diatomic alcohols, glycerin is used as triatomic alcohols and erythritols, for example, pentaerythritol are used as polyatomic alcohols. The compound relating to lower aldehydes or lower ketones, for example, formaldehyde, acetaldehyde, acetone, methylethylketone, diethylketone or cyclohexane are used as a carbonyl compound. The alcohols are in the form of aliphatic alcohols containing up to five carbon atoms, substantially ethanol. The inventive gasoline automotive fuel means a gasoline or an alcohol-gasoline composition.06-30-2011

Maxime Makarov, Viroflay FR

Patent application numberDescriptionPublished
20100212631COMBUSTION ENGINE AND METHOD OF CONTROLLING A COMBUSTION ENGINE - An internal combustion engine including: a pulse current generator; at least one electrode including at least one tip; a mechanism controlling the electrical supply to the electrode by the generator; and a combustion chamber in which the tip of the electrode is positioned, the tip being separated from the inner wall of the chamber by a minimum separation distance. The current generator and the electrode are configured such that the power density generated while the electrode is being supplied is less than 1008-26-2010
20110048355OPTIMIZATION OF THE EXCITATION FREQUENCY OF A RADIOFREQUENCY PLUG - A device for generating a radiofrequency plasma, which includes a supply module applying, on an output interface, an excitation signal at a setpoint frequency, adapted for generating a spark at the output of a plasma-generation resonator connected to the output interface of the power module, and a control module supplying the setpoint frequency to the power module upon a command for generating the radiofrequency plasma. The control module is configured to determine an optimal excitation frequency, to adapt the setpoint frequency to the resonance conditions of the device after formation of the spark.03-03-2011
20110080095FILAMENT ELECTRICAL DISCHARGE ION SOURCE - Filament electric discharge ion source (04-07-2011
20110139135POWER SUPPLY CONTROL FOR SPARK PLUG OF INTERNAL COMBUSTION ENGINE - A method for controlling the power supply of a radiofrequency spark plug in an internal combustion engine up to an electric voltage sufficient for generating a highly branched spark. To this end, the electric voltage for powering the spark plug is increased step by step up to an adequate voltage adapted for ignition.06-16-2011
20110146816DEVICE FOR DISINFECTING A MOTOR VEHICLE AIR-CONDITIONING SYSTEM - The invention relates to a device (06-23-2011
20110203543MONITORING OF THE EXCITATION FREQUENCY OF A RADIOFREQUENCY SPARK PLUG - A radiofrequency plasma generating device, including: a control module generating a control signal at a control frequency, a power supply circuit including a breaker switch controlled by the control signal, the breaker switch applying an excitation signal to an output of the power supply circuit at the control frequency defined by the control signal, a resonator exhibiting a resonant frequency of greater than 1 MHz, connected to the output of the power supply circuit and adapted to generate a voltage for making a spark when it is excited by the excitation signal, and a mechanism monitoring the control module and configured to modify the frequency of the resonator excitation signal in a manner synchronous with the control signal, during application of the excitation signal.08-25-2011

Patent applications by Maxime Makarov, Viroflay FR

Maxime Makarov, Gennevilliers FR

Patent application numberDescriptionPublished
20110057565DEVICE AND METHOD OF SUPPLYING POWER TO AN ELECTRON SOURCE, AND ION-BOMBARDMENT-INDUCED SECONDARY-EMISSION ELECTRON SOURCE - The power supply device (03-10-2011
20110057566PULSED ELECTRON SOURCE, POWER SUPPLY METHOD FOR PULSED ELECTRON SOURCE AND METHOD FOR CONTROLLING A PULSED ELECTRON SOURCE - The invention relates to a pumped electron source (03-10-2011

Roman Makarov, Bat Yam IL

Patent application numberDescriptionPublished
20100264590SOCCER BOARD GAME - A soccer board game and a method for playing it by first and second contestants is disclosed. The game board included a board comprising a grid of distinctly marked squares with soccer field markings. The soccer field markings include a half line dividing the field into two half fields, a kick-off circle on the half line, two opposite goal boxes located on opposite ends of the field, a five-zone and a sixteen-zone areas adjacent each of the goal boxes. The board game includes at least one die; a ball; and opponent first and second teams of players, each team pertaining to one of the contestants.10-21-2010

Sergey Makarov, Bat Yam IL

Patent application numberDescriptionPublished
20100264590SOCCER BOARD GAME - A soccer board game and a method for playing it by first and second contestants is disclosed. The game board included a board comprising a grid of distinctly marked squares with soccer field markings. The soccer field markings include a half line dividing the field into two half fields, a kick-off circle on the half line, two opposite goal boxes located on opposite ends of the field, a five-zone and a sixteen-zone areas adjacent each of the goal boxes. The board game includes at least one die; a ball; and opponent first and second teams of players, each team pertaining to one of the contestants.10-21-2010

Sergey Nikolaevich Makarov, Novosibirsk RU

Patent application numberDescriptionPublished
20100194236Capacitive Electric Current Generator - A capacitive generator has a generator circuit (G) and a charge priming circuit (P) consisting of variable capacitors (08-05-2010

Vadim Makarov, Moscow RU

Patent application numberDescriptionPublished
20080255166Dithiocarbamate derivatives and their use as antibacterial agents - The invention relates to the use of dithiocarbamate derivatives for the therapeutic or prophylactic treatment of infectious diseases in mammals (humans and animals) caused by bacteria, especially diseases like tuberculosis (TB) and lepra caused by mycobacteria and infectious diseases caused by staphylococci. The invention further relates to novel dithiocarbamate derivatives of the formula (I), wherein X is a bivalent residue selected from the group consisting of formulae having excellent antibacterial activities, and to pharmaceutical preparations containing the same.10-16-2008

Vadim Makarov, Moskow RU

Patent application numberDescriptionPublished
201000100184-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents - 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine derivatives of general formula (I), pharmaceutically acceptable salts thereof, method for preparation of the aforesaid compounds and their use as antiviral agents.01-14-2010
20100286130ANTIMICROBIAL COMPOUNDS, THEIR SYNTHESIS AND THEIR USE FOR TREATMENT OF MAMMALIAN INFECTIONS - The present invention relates to compounds of Formula (I)11-11-2010

Valery Gennadievich Makarov, St. Petersburg RU

Patent application numberDescriptionPublished
20090081321THERAPEUTIC AND COSMETIC BALSAM - The invention relates to cosmetics and medicine and can be used for skin care or in form of a warming balsam. The present oily balsam represents a homogenous system and comprises a complex of the following oils, emollients and extracts: Macadamia oil, Bosvellia serrate extract (olibanum), isopropyl myristate, vegetable oil, oil extract of red hot pepper standardised for capsaicin (10%), polyethylsiloxane (PES-4), lecitine and a flavouring agent at a certain ratio of the components. The balsam has a more pronounced prolonged warming, anaesthetic, anti-inflammatory and regeneration action and has pleasant organoleptic properties and texture.03-26-2009
20090142419ANTI-INFLAMMATORY EXTRACT AND AGENT AND METHOD FOR THE PRODUCTION THEREOF - The invention relates to the pharmaceutical industry, in particular to producing herbal remedy for integrally treating various inflammatory diseases. The inventive remedy comprises a dry 06-04-2009

Vladimir Makarov, Toronto CA

Patent application numberDescriptionPublished
20110219216Mechanism for Performing Instruction Scheduling based on Register Pressure Sensitivity - A mechanism for performing instruction scheduling based on register pressure sensitivity is disclosed. A method of embodiments of the invention includes performing a preliminary register pressure minimization on program points during a compilation process of a software program running on a virtual machine of a computer system. The method further includes calculating a register pressure at each of the program points, detecting an instruction to be scheduled, and performing instruction scheduling of the instruction based on a current register pressure at a current scheduling point and potential register pressures at subsequent scheduling points.09-08-2011
20110219364Mechanism for Performing Register Allocation of Program Variables Based on Priority Spills and Assignments - A mechanism for performing register allocation based on priority spills and assignments is disclosed. A method of embodiments of the invention includes repetitively detecting fat points during a compilation process of a software program running on a virtual machine of a computer system, each fat point representing a program point having a high register pressure, the high register pressure occurs when a number of live program variables of the software program living at a given program point of the software program is greater than a number of available processor registers of the computer system. The method further includes choosing a fat point with a highest register pressure, selecting a live program variable having a lowest priority at the chosen fat point, and spilling the lowest priority live program variable to memory of the computer system.09-08-2011