Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Majercak
David Majercak, Stewartsville, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100094334 | PLICATION DEVICE WITH FORMABLE LINEAR FASTENER FOR USE IN THE DIRECT PLICATION ANNULOPLASTY TREATMENT OF MITRAL VALVE REGURGITATION - A system for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular tissue each fixed by a retaining clip is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a prolapsable crossing catheter. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. The plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a formable linear retainer clip is deployed by the plication device in order to retain the plicated tissue in the plicated form. The formable linear retainer is formed into a reverse “C” clip by the jaws of the plication device acting in conjunction with a retainer pusher. | 04-15-2010 |
| 20110034989 | RAPID-EXCHANGE BALLOON CATHETER SHAFT AND METHOD - A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern. | 02-10-2011 |
David Christopher Majercak, Stewartsville, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110071614 | STENT - GRAFT SUTURE LOCKS - Modified suture knots may be utilized to effective anchor one stent-graft to another stent-graft wherein the stent-grafts are normally connected via an interference fit in an overlap configuration. The sutures that are utilized to affix the graft material to the underlying stent structure may be modified to have a profile that allow it to lock and secure it to another stent-graft or a vessel into which it is implanted. | 03-24-2011 |
John M. Majercak, Wayne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090047702 | Method for Identifying Modulators of Keah6 Useful for Treating Alzheimer's Disease - Methods for identifying modulators of KEAH6 are described. The methods are particularly useful for identifying analytes that antagonize KEAH6's effect on processing of amyloid precursor protein to Aβ peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease. | 02-19-2009 |
| 20090068678 | Method for identifying modulators of NOAH10 useful for treating Alzheimer's disease - Methods for identifying modulators of NOAH10 are described. The methods are particularly useful for identifying analytes that antagonize NOAH10's effect on processing of amyloid precursor protein (APP) to amyloid beta (Aβ) peptide and are useful for identifying analytes that can be used for treating Alzheimer disease. | 03-12-2009 |
| 20100041026 | Method for Identiflying Modulators of Rufy2 Useful for Treating Alzheimer's Disease - Compositions and methods for identifying modulators of RUFY2 are described. The methods are particularly useful for identifying analytes that antagonize RUFY2's effect on processing of amyloid precursor protein to Aβ peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease. | 02-18-2010 |