Majercak
David Majercak, Stewartsville, NJ US
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20100094334 | PLICATION DEVICE WITH FORMABLE LINEAR FASTENER FOR USE IN THE DIRECT PLICATION ANNULOPLASTY TREATMENT OF MITRAL VALVE REGURGITATION - A system for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular tissue each fixed by a retaining clip is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a prolapsable crossing catheter. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. The plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a formable linear retainer clip is deployed by the plication device in order to retain the plicated tissue in the plicated form. The formable linear retainer is formed into a reverse “C” clip by the jaws of the plication device acting in conjunction with a retainer pusher. | 04-15-2010 |
20110034989 | RAPID-EXCHANGE BALLOON CATHETER SHAFT AND METHOD - A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern. | 02-10-2011 |
David Majercak, Livermore, CA US
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20150374517 | ENDOPROSTHESIS ANCHORING AND SEALING - Described are various embodiments of an improved endoprosthesis that includes a generally cylindrical graft portion that extends along a longitudinal axis to define a flow passage and a plurality of stent hoops. The plurality of stent hoops are connected to the graft portion and disposed in a spaced apart relationship along the longitudinal axis. There is at least a first suture disposed along on the outer surface of the main body. The first suture connects at least two of the spaced apart stent hoops together. The first suture also includes unidirectional barbs (or multidirectional barbs) configured to reduce movement of the main body with respect to a direction of blood flow in an artery. | 12-31-2015 |
20160081709 | CATHETER SYSTEMS AND METHODS FOR RE-ENTRY IN BODY VESSELS WITH CHRONIC TOTAL OCCLUSION - A catheter system and corresponding methods are provided for accessing a blood vessel true lumen from a sub-intimal plane of the vessel. The catheter includes components that are symmetric about the longitudinal axis and allow for reentry without the need to ensure a correct orientation of the cannula. | 03-24-2016 |
David C. Majercak, Livermoore, CA US
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20140222132 | PERCUTANEOUS ENDOPROSTHESIS USING SUPRARENAL FIXATION AND BARBED ANCHORS - An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device. | 08-07-2014 |
David C. Majercak, Livermore, CA US
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20160081823 | ENDOPROSTHESIS WITH PREDETERMINED CURVATURE FORMED BY TRI-TETHERS - Described are various embodiments of an improved endoprosthesis that includes a generally tubular graft, a plurality of independent stent hoops connected to the graft and at least one suture. The at least one suture connects one apex of one stent hoop to two apices of another stent hoop to reduce a predetermined distance between distinct stent hoops so that in a released configuration in a body vessel, the stent-graft is curved away from the longitudinal axis to conform to the body vessel and reduce formation of a gap between one end of the stent-graft with an inner surface of the body vessel. | 03-24-2016 |
David Christopher Majercak, Stewartsville, NJ US
Patent application number | Description | Published |
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20110071614 | STENT - GRAFT SUTURE LOCKS - Modified suture knots may be utilized to effective anchor one stent-graft to another stent-graft wherein the stent-grafts are normally connected via an interference fit in an overlap configuration. The sutures that are utilized to affix the graft material to the underlying stent structure may be modified to have a profile that allow it to lock and secure it to another stent-graft or a vessel into which it is implanted. | 03-24-2011 |
20110190664 | HIGHLY FLEXIBLE TUBULAR DEVICE FOR MEDICAL USE - The invention relates to an elongated torque tube for use in medical applications. The torque tube comprises an elongated tubular structure having a cylindrical cross section and defining a longitudinal axis and a circumferential axis, the elongated tubular structure including a helical cut having a finite thickness and extending along the length of the elongated tubular structure, the helical cut being oriented along the circumferential axis and including a plurality of flexural units defined by discontinuous cuts aligned with the circumferential axis. | 08-04-2011 |
20110190732 | HIGHLY FLEXIBLE TUBULAR DEVICE WITH HIGH INITIAL TORQUE RESPONSE FOR MEDICAL USE - The invention relates to an elongated torque tube for use in medical applications. The torque tube comprises an elongated tubular structure having a cylindrical cross section and defining a longitudinal axis and a circumferential axis, the elongated tubular structure including a helical cut having a finite thickness and extending along the length of the elongated tubular structure, the helical cut being aligned with the circumferential axis and including a plurality of protrusions extending along the longitudinal axis, the protrusions defined by discontinuous cuts aligned with the longitudinal axis. | 08-04-2011 |
John M. Majercak, Wayne, PA US
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20090047702 | Method for Identifying Modulators of Keah6 Useful for Treating Alzheimer's Disease - Methods for identifying modulators of KEAH6 are described. The methods are particularly useful for identifying analytes that antagonize KEAH6's effect on processing of amyloid precursor protein to Aβ peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease. | 02-19-2009 |
20090068678 | Method for identifying modulators of NOAH10 useful for treating Alzheimer's disease - Methods for identifying modulators of NOAH10 are described. The methods are particularly useful for identifying analytes that antagonize NOAH10's effect on processing of amyloid precursor protein (APP) to amyloid beta (Aβ) peptide and are useful for identifying analytes that can be used for treating Alzheimer disease. | 03-12-2009 |
20100041026 | Method for Identiflying Modulators of Rufy2 Useful for Treating Alzheimer's Disease - Compositions and methods for identifying modulators of RUFY2 are described. The methods are particularly useful for identifying analytes that antagonize RUFY2's effect on processing of amyloid precursor protein to Aβ peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease. | 02-18-2010 |