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Maione
Domenico Maione, Siena IT
| Patent application number | Description | Published |
|---|---|---|
| 20100015168 | IMMUNOGENIC COMPOSITIONS FOR STREPTOCOCCUS AGALACTIAE - The invention relates to immunogenic polypeptides derived from epitopes in a Streptococcus agalactiae (“GBS”) protein GBS 80 and their use as prophylactic, diagnostic and therapeutic compositions. The invention also provides nucleic acids encoding the immunogenic polypeptides. Also provided are vectors useful for making such immunogenic polypeptides and host cells transformed with such vectors. In particular, the invention relates to a group immunogenic polypeptides derived from GBS 80. The compositions may include one or more of the immunogenic polypeptides either alone or with other antigenic components. For example, the immunogenic polypeptides may be combined with other GBS antigens to provide therapeutic compositions with broader range. In addition, the immunogenic polypeptides may also include flanking portions of the GBS 80 protein. | 01-21-2010 |
| 20100215683 | PROTECTIVE ANTIGENS FOR GROUP B STREPTOCOCCUS HYPERVIRULENT STRAINS - The invention provides protective antigens for Group B streptococcus hypervirulent strains. The fragments are useful in vaccine compositions to induce protection against | 08-26-2010 |
| 20110052620 | HYBRID POLYPEPTIDES COMPRISING GBS-80 AND SPB1 PROTEINS OF STREPTOCOCCUS - GBS antigens GBS-80 and Spb1 are expressed in a single polypeptide chain, preferably with Spb1 upstream of GBS-80. Thus the invention provides a polypeptide comprising an amino acid sequence NH | 03-03-2011 |
| 20110206692 | CONFORMERS OF BACTERIAL ADHESINS - The invention relates to isolated or purified bacterial adhesin conformers, preferably with improved stability and/or immunogenicity. In a preferred aspect, the invention comprises an isolated bacterial adhesin conformer F. Also provided are methods of isolation and/or separation of such adhesin conformers. The compositions may include one or more of the immunogenic polypeptides either alone or with other antigenic components. For example, the immunogenic polypeptides may be combined with other bacterial antigens to provide therapeutic compositions with broader range. | 08-25-2011 |
Domenico Maione, Castelnuovo Berardenga IT
| Patent application number | Description | Published |
|---|---|---|
| 20080220010 | Immunogenic Compositions for Streptococcus Agalactiae - This application relates to Group B | 09-11-2008 |
Domenico Maione, Sienna IT
| Patent application number | Description | Published |
|---|---|---|
| 20110110982 | IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE - The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B | 05-12-2011 |
Emiliano Maione, Bagno A Ripoli IT
| Patent application number | Description | Published |
|---|---|---|
| 20110200486 | DEVICE FOR PREPARING AND/OR TREATING A BIOLOGICAL SAMPLE - A device for preparing and/or treating a biological sample including an assembly of storage chambers and/or reaction chambers intended for receiving a fluid, the chambers being separated by walls so as to form an assembly of adjacent chambers. The device includes a base and a drawer including the assembly of adjacent chambers, the drawer being movable in relation to the base, the drawer including a contact surface connected to first means for establishing fluid communication connected to the inside of at least one chamber, the contact surface of the drawer being intended to be positioned facing a contact surface of the base including at least one position at which second means for fluid communication connected to detection means are placed. | 08-18-2011 |
Emiliano Maione, Bagno A Ripoli (firenze) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110250680 | AUTOMATED SYSTEM FOR THE LYSIS OF MICROORGANISMS PRESENT IN A SAMPLE, FOR EXTRACTION AND FOR PURIFICATION OF THE NUCLEIC ACIDS OF SAID MICROORGANISMS FOR PURPOSES OF ANALYSIS - The present invention relates to, among other things, a device for collecting airborne microorganisms, said device having: | 10-13-2011 |
Sabatino Maione, Bacoli IT
| Patent application number | Description | Published |
|---|---|---|
| 20120115808 | PHARMACOLOGICAL PREPARATION FOR TOPICAL USE CONTAINING N-PALMITOYL-VANILLAMIDE - The present invention relates to topical preparations containing N-palmitoyl-vanillamide having hyperalgesic activity. In particular, the invention relates to N-palmitoyl-vanillamide for use in the treatment of pathologies selected from: post-herpetic neuralgia, neuralgia of trigeminus, occipital neuralgia, dental neuralgia, glottopharyngeal neuralgia, uremic neuralgia, diabetic neuralgia, headache of different origin, neuropathic itch, neurogenic itch, uremic itch, vulvodinia, vulvar vestibulitis, ano-rectal pain and itch, balano-preputial pain and itch, painful urogenital disorders of dogs and cats, psoriasis-associated pruritus and pain, itching skin diseases (e.g. atopic dermatitis) in the human and veterinary field, muscular pain, pain of the tendon, osteoarthritis associated pain in humans, dogs and cats; painful eye diseases in the human and veterinary field, inflammatory pathologies of the oral cavity in the human and veterinary field. | 05-10-2012 |
Theodore E. Maione, Wakefield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080249715 | Method for identifying markers - The invention is a method for identifying markers associated with the presence of a predetermined characteristic comprising accumulating spectral data from a sample known to have a predetermined characteristic, identifying a spectral feature which is indicative of the predetermined characteristic, and identifying a marker associated with the spectral feature. | 10-09-2008 |
Theodore E. Maione, Cambridge, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110190214 | Advantageous Salts of Mu-Opiate Receptor Peptides - The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions. | 08-04-2011 |
Theodore E. Maione, Troy, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110065648 | ADVANTAGEOUS MU-OPIATE RECEPTOR PEPTIDE COMPOUNDS - The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their activity. | 03-17-2011 |
| 20110287040 | MATERIALS AND METHODS FOR TREATMENT OF INFLAMMATION - The subject invention pertains to peptides and salts thereof that are useful as anti-inflammatory agents and to compositions containing such peptides and salts as active ingredients. Specifically exemplified herein are endomorphin-1 peptide (EM-1), analogs and salts thereof, and uses for modulation of calcitonin gene-related peptide (CGRP) production and/or substance P (SP) and for treatment of inflammation, particularly neurogenic inflammation. | 11-24-2011 |