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Mahmood, US

Ashfaq Mahmood, Newton Center, MA US

Patent application numberDescriptionPublished
20080226550SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS - The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tumors, e.g., carcinomas, melanomas and other tumors. In another embodiment, the invention relates to methods of imaging tumors using radiolabeled metal complexes. Preferred radiolabeled complexes for imaging tumors include technetium and rhenium complexes. The high tumor uptake and significant tumor/nontumor ratios of the technetium complexes of the invention indicate that such small technetium-99m-based molecular probes can be developed as in-vivo diagnostic agents for melanoma and its metastases. In yet another embodiment, the invention relates to methods of treatment of tumors using a radiolabeled metal complex as a radiopharmaceutical agent to treat the tumor.09-18-2008

Patent applications by Ashfaq Mahmood, Newton Center, MA US

Ayesha Mahmood, Orlando, FL US

Patent application numberDescriptionPublished
20090075282ARTIFICIAL TISSUE CONSTRUCTS COMPRISING ALVEOLAR CELLS AND METHODS FOR USING THE SAME - The present invention comprises artificial tissue constructs that serve as in vitro models of mammalian lung tissue. The artificial tissue constructs of the present invention comprise functionally equivalent in vitro tissue scaffolds that enable immunophysiological function of the lung. The constructs can serve as novel platforms for the study of lung diseases (e.g., interstitial lung diseases, fibrosis, influenza, RSV) as well as smoke- and smoking-related diseases. The artificial tissue constructs of the present invention comprise the two components of alveolar tissue, epithelial and endothelial cell layers.03-19-2009

Hamid Mahmood, Seattle, WA US

Patent application numberDescriptionPublished
20110185282User-Interface-Integrated Asynchronous Validation for Objects - An asynchronous data validation mechanism integrated into a user interface by a binding engine is provided. Application object properties are bound to user interface data fields. The asynchronous validation mechanism communicates with a validator and with the object properties. Data input to a single field can be flagged with multiple validation errors. Multiple validation errors can also be associated to the object overall rather than being associated with particular properties of the object. Inconsistency between inputs to different data fields can result in a cross-property validation error. A single flag indicates whether the business object has any validation errors. Different validation errors may have different visualization types, and the business object may have validation errors of different data types, rather than being limited to strings.07-28-2011

Hikmat F. Mahmood, Bloomfield Hills, MI US

Patent application numberDescriptionPublished
20080238146FRONT RAIL HAVING CONTROLLED THICKNESS FOR ENERGY ABSORPTION - A frame rail for a vehicle that is provided between vehicle frame and the bumper of a vehicle that has a thickness that varies from the front end of the rail to the back end of the rail. The compressive strength of the rail increases from the front end of the rail to the back end of the rail. The rail is rectangular in shape and the thickness of the rail is continuously increased to improve progressive crush characteristics of the rail under an oblique loading. A rail may be provided by providing a tubular rail having a plurality of ring shaped segments that have incrementally increasing thickness. Alternatively, the rail may have a uniformly increasing thickness from the front end to the back end.10-02-2008
20100026053Dual Cell Body Side Rail for Automotive Vehicles - A body side rail construction for an automotive vehicle is formed in a dual cell configuration. A reversed C-shaped channel is welded to the closed section of the conventional roof side rail member to enable the body side rail member to be a smaller section that is less susceptible to buckling as the body side rail member transfers load to the front and rear corner pillars. The C-shaped cross-sectional configuration presents advantages for manufacturing as it can be shaped to provide the attaching brackets and horns for mounting the front header, roof bow, and rear header members to the body side rail without the addition of individual end items to serve this function. From a shipping density standpoint, this design gives maximum structure while maintaining good rack density that enables relatively straight parts to be nested together while still providing the increased section strength required for enhanced roof performance.02-04-2010
20100026054Moon Roof Frame Module for Reinforcement of Automotive Roof - A moon roof frame module is sized to span between the laterally spaced roof side rails of an automotive roof frame structure and is welded to the opposing roof side rails to be integrated into the roof frame structure. As a result, the moon roof assembly serves as a load path member to reinforce the automotive roof structure. The integrated moon roof frame module will receive roll over forces and increase the strength of the roof structure of an automotive vehicle. The moon roof frame module includes a U-shaped roof panel that is welded to the opposing roof side rails and provides a reinforcing cross member located forwardly of the moon roof opening. A second cross member positioned rearwardly of the moon roof opening increases rigidity of the reinforcing moon roof frame module.02-04-2010
20100237661VEHICLE BODY STRUCTURE - A vehicle body structure having improved roof support characteristics is provided. The structure includes a roof rail integral to an A-pillar and a support pillar. The structure further includes a cross member. The A-pillar includes an inner surface, an outer surface, and a wall therebetween. The roof rail extends downwardly at a front end of the roof rail and extends downwardly at a rear end of the roof rail. The roof rail is integral to a one piece hollow A-pillar at the front end of the roof rail. The support pillar also includes an inner surface, an outer surface, and a wall therebetween. The support pillar also includes a tubular lower section that extends upwardly from the rocker. The upper section of the support pillar is integral to the rear end of the roof rail.09-23-2010
20110233947Zero Stack-Up Telescopically Collapsible Energy Absorbing Rail and Bracket Assembly - An energy absorbing assembly for a vehicle that has a bumper and a frame. A receptacle is defined within the frame. A collapsible member is provided between the bumper and a recessed location spaced away from the bumper in the receptacle. The collapsible member may collapse at least partially into the receptacle in the event of a collision.09-29-2011

Patent applications by Hikmat F. Mahmood, Bloomfield Hills, MI US

Khalid Mahmood, Princeton, NJ US

Patent application numberDescriptionPublished
20110081308EXTRACTS OF PHYLLANTHUS NIRURI - A method of making a low molecular weight fraction of 04-07-2011

Khalid Mahmood, Palo Alto, CA US

Patent application numberDescriptionPublished
20100279987COMPOSITIONS CONTAINING CHALCONES AND USE THEREOF - The present invention features composition comprising a chalcone and the use thereof for treating acne and reducing the appearance of oil or pores on the skin, hair and scalp.11-04-2010

Khalid Mahmood, Batavia, CA US

Patent application numberDescriptionPublished
20100202989METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS - A method of reducing the appearance of skin conditions associated with loss of skin tightness, skin firmness, or dark circles under the eyes with topical compositions comprising compounds of any of the Formulae I or Ia as described herein, is disclosed.08-12-2010

Patent applications by Khalid Mahmood, Batavia, CA US

Khalid Mahmood, South Hadley, MA US

Patent application numberDescriptionPublished
20120045407COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF - Provided are compositions comprising botanical extracts from certain species of the genus 02-23-2012
20120045490COMPOSITIONS COMPRISING PAULOWNIA TOMENTOSA WOOD EXTRACTS AND USES THEREOF - Provided are compositions comprising an extract of 02-23-2012
20120045491COMPOSITIONS COMPRISING PAULOWNIA TOMENTOSA WOOD EXTRACTS AND USES THEREOF - Provided are compositions comprising an extract of 02-23-2012
20120045492COMPOSITIONS COMPRISING PAULOWNIA TOMENTOSA WOOD EXTRACTS AND USES THEREOF - Provided are compositions comprising an extract of 02-23-2012
20120045529COMPOSITIONS COMPRISING PAULOWNIA TOMENTOSA WOOD EXTRACTS AND USES THEREOF - Provided are compositions comprising an extract of 02-23-2012
20120045530COMPOSITIONS COMPRISING PAULOWNIA TOMENTOSA WOOD EXTRACTS AND USES THEREOF - Provided are compositions comprising an extract of 02-23-2012
20120045531METHODS OF TREATING CELLULITE - Provided are methods of treating cellulite, the methods comprising applying to skin in need of cellulite treatment a composition comprising paulownin or an extract of 02-23-2012

Khurram Mahmood, Walnut Creek, CA US

Patent application numberDescriptionPublished
20110197138PREVIEW RELATED ACTION LIST - Previewing content included in an enterprise database associated with an enterprise system is disclosed. A first indication is received for an overlay object associated with an object from the enterprise database that is being displayed. an action list is dynamically determined associated with the object being displayed using a first method to retrieve actions from the enterprise system that are associated with the object being displayed. The action list is provided to the overlay object. Content associated with the object is dynamically determined using a second method to retrieve content from the enterprise system. The content is provided to the overlay object. The overlay object is displayed to preview the content included in the enterprise database and to provide the action list.08-11-2011

Kutub Mahmood, Rockville, MD US

Patent application numberDescriptionPublished
20080233150RESPIRATORY SYNCYTIAL VIRUS-VIRUS LIKE PARTICLE (VLPS) - The present invention discloses and claims virus like particles (VLPs) that express and/or contains RSV proteins. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising VLPs of the inventions. The invention also includes methods of making and administrating VLPs to vertebrates, including methods of inducing immunity to infections, including RSV.09-25-2008
20090017066NOVEL VLPS DERIVED FROM CELLS THAT DO NOT EXPRESS A VIRAL MATRIX OR CORE PROTEIN - The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins are derived from fragments of influenza membrane proteins fused to heterologous proteins. The invention includes antigenic formulations and vaccines comprising VLPs of the invention as well as methods of making and administering VLPs to vertebrates, including methods of inducing immunity to infections, such as influenza.01-15-2009

Patent applications by Kutub Mahmood, Rockville, MD US

Kutub Mahmood, Cupertino, CA US

Patent application numberDescriptionPublished
20100129401Functional Influenza Virus Like Particles (VLPs) - The present invention discloses and claims virus like particles (VLPs) that express and/or contains seasonal influenza virus proteins, avian influenza virus proteins and/or influenza virus proteins from viruses with pandemic potential. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising VLPs of the inventions. The invention also includes methods of making and administrating VLPs to vertebrates, including methods of inducing substantial immunity to either seasonal and avian influenza, or at least one symptom thereof.05-27-2010
20100247574CHIMERIC NEWCASTLE DISEASE VIRUS VLPs - The present invention discloses and claims chimeric virus like particles (VLPs) that express and/or contains Newcastle disease matrix protein. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising chimeric VLPs of the inventions. The invention also includes methods of making and administrating chimeric VLPs to vertebrates, including methods of inducing immunity to infections.09-30-2010

Meena Mahmood, Little Rock, AR US

Patent application numberDescriptionPublished
20100104652Use of advanced nanomaterials for increasing sepecific cell functions - Disclosed herein are methodologies and compositions for enhancing cellular functions, which can be used in a variety of biological applications.04-29-2010
20100285138COMPOSITIONS COMPRISING NANOPARTICLES AND APOPTOTIC AGENTS AND METHODS OF USE - Compositions comprising nanoparticles, such as silver or gold nanoparticles or carbon nanotubes (CNTs), and apoptotic agents are described. The nanoparticles can significantly enhance the cancer chemotherapeutic effects of the apoptotic agents. In particular, a highly increased anti-tumor activity has been demonstrated for the combination of etoposide and CNTs against HeLa cells compared to the administration of either etoposide alone or nanoparticles alone. Data provided by flow cytometry, Caspase 3 and other methods, suggest a strong interaction between the nanoparticles and the cellular structure, which can result in the improved effectiveness of chemotherapeutic agents. These findings provide potential new cancer therapies by carefully selecting the right combination of cytostatic drugs and nanostructural materials which synergistically provide significantly greater curative rates.11-11-2010

Munir Mahmood, Bellevue, WA US

Patent application numberDescriptionPublished
20090083367User profile aggregation - User profile data that may be spread across different service providers and that may vary across different service providers can be aggregated to provide an aggregate user profile. An aggregate user profile can be generated regardless of, among other things, varying user profile semantics, differing data formats, data item conflicts, evolving server protocols and interfaces, and updates to the number, identity, location, and type of servers upon which the service providers are maintained.03-26-2009

Nadir Ahmeduddin Mahmood, Calabasas, CA US

Patent application numberDescriptionPublished
20080318870SYNTHETIC BILE ACID COMPOSITIONS AND METHODS - Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.12-25-2008
20100160276SYNTHETIC BILE ACID COMPOSITIONS AND METHODS - Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.06-24-2010

Tahir A. Mahmood, La Jolla, CA US

Patent application numberDescriptionPublished
20100196445SYSTEMS AND METHODS FOR DELIVERY OF BIOLOGICALLY ACTIVE AGENTS - The invention provides methods and devices for the delivery of therapeutic or biologically active agents to tissue, for example by facilitating the transport of said agents through the skin of a human or animal. Therapeutic agents include various botulinum neurotoxin (BoNT) and other biologically active agents, which can be delivered across the skin and into the dermis using multiple strategies including microneedle drug delivery, transport moieties, or penetration enhancers such as extracellular matrix-digestive enzymes.08-05-2010

Tanveer Fathima Mahmood US

Patent application numberDescriptionPublished
20100329521SYSTEMS AND METHODS FOR CARDIAC VIEW RECOGNITION AND DISEASE RECOGNITION - A method for recognizing heart diseases in a cardiac echo video of a heart with an unknown disease using a spatio-temporal disease model derived from a training echo video, comprising the steps of: generating a plurality of training models for heart diseases, wherein the cardiac echo videos are each derived from a known viewpoint and the disease of the heart is known; analyzing the video of the heart with the unknown disease by fitting a model of shape and motion for each frame and combining the results across the frames; and, reporting the disease using a classification method for choosing among the diseases of interest.12-30-2010

Umar Mahmood, Boston, MA US

Patent application numberDescriptionPublished
20090207412Multi-channel Optical Imaging - A beam splitter array includes first and second beam splitters and a reflector to reflect part of a beam from the second splitter. The first splitter outputs a first beam having a power spectral density comprising a substantial portion of a white light spectrum from a first output port, and a second beam of optical radiation having a power spectral density comprising a substantial portion of a first non-white spectrum and a substantial portion of a second non-white spectrum from a second output port, from an input beam received at a first angle of incidence. The second splitter receives the second beam at a second incidence angle, and reflects a substantial portion of the second beam having a power spectral density comprising the first non-white light spectrum, and transmits a substantial portion of the second beam having a power spectral density comprising the second non-white light spectrum.08-20-2009

Umar Mahmood, Winchester, MA US

Patent application numberDescriptionPublished
20100166669METHODS OF IMAGING INFLAMMATION IN PANCREATIC ISLETS - Described are non-invasive methods for imaging pancreatic inflammation in living mammals using Magnetic Nanoparticle Probes (MNPs).07-01-2010
20110152501Activatable Imaging Probes - The invention relates to activatable imaging probes that include a chromophore attachment moiety and a plurality of chromophores, such as near-infrared chromophores, chemically linked to the chromophore attachment moiety so that upon activation of the imaging probe by interaction with a target molecule the optical properties of the plurality of chromophores are altered. The probe optionally includes protective chains or chromophore spacers, or both. Also disclosed are methods of using the imaging probes for in vivo and in vitro optical imaging.06-23-2011

Patent applications by Umar Mahmood, Winchester, MA US

Zafar Mahmood, Round Rock, TX US

Patent application numberDescriptionPublished
20090276785System and Method for Managing a Storage Array - Systems and methods for managing a storage array are disclosed. A method may include segmenting each of a plurality of physical storage resources into a first storage area and a second storage area. The method may also include activating a first logical unit including each first storage area of the plurality of physical storage resources. The method may additionally include placing at least one designated physical resource of the plurality of physical storage resources in a powersave mode. The method may further include activating a second logical unit including the second storage areas of some of the plurality of physical storage resources but not the at least one designated physical storage resource. Moreover, the method may include storing data associated with a write operation intended for the at least one designated physical storage resource to the second logical unit.11-05-2009