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Maguire, MA

Casey Maguire, Arlington, MA US

Patent application numberDescriptionPublished
20120122182GAUSSIA LUCIFERASE VARIANT FOR HIGH-THROUGHPUT SCREENING - Described herein is a variant of wild type Gaussia luciferase that catalyzes glow-type emission kinetics suited for high-throughput functional screening applications. Polypeptides, functional fragments, variants, and nucleic acids that encode the enhanced luciferase are further described. One such polypeptide corresponds to wild type Gaussia luciferase with a substitution mutation of I for M at position 43 of the mature peptide. Methods of use, assay systems and kits that contain the polypeptides and/or nucleic acids are further described.05-17-2012

Daniel Maguire, Burlington, MA US

Patent application numberDescriptionPublished
20110244704EXTENSION CABLE WITH SEQUENCED DISCONNECT - A breakaway cable is provided with a plug that has a number of wires that are arranged so as to disconnect in a predetermined sequence. The disconnect plug is designed to fit into a standard plug assembly. This end of the plug presents the same set of pins as a truck, thus extending the existing cable by the extender length. The breakaway cable is configured to break in a controlled manner in the event a vehicle to which the cable is connected should pull away.10-06-2011
20120245792PORTABLE TRUCK TESTER - A hand held portable truck safety equipment tester uses loading rack criteria to confirm proper operation of the truck but is contained in a small portable battery operated unit. This unit allows for correlation to a rack controller's test and includes direct readout via an LED screen showing the error condition. Additionally, the tester has the capability to test all types of trucks without the need for adapters to accommodate different connectors and allows for remote diagnostics. The tester automatically determines which type of sensor and what grounding system is used.09-27-2012

George Maguire, Newton, MA US

Patent application numberDescriptionPublished
20100151533Synthesis of (6S)-5methyl-5,6,7,8-tetrahydrofolic acid - A process for the large-scale chemoenzymatic production of (6S)-5-methyl-5,6,7,8-tetrahydrofolic acid, also known as (6S)-5-methylTHFA, the process comprising the steps of: (1) reducing folic acid (FA) so as to yield dihydrofolic acid (DHFA); (2) stereoselectively reducing DHFA with dihydrofolate reductase (DHFR) in the presence of NADP/NADPH, glucose and GluDH so as to yield (6S)-THFA; (3) converting (6S)-THFA to (6S)-5-methylTHFA; and (4) isolating (6S)-5-methylTHFA.06-17-2010
20120315679SYNTHESIS OF (6S)-5,6,7,8-TETRAHYDROFOLIC ACID - A process for the large-scale chemoenzymatic production of (6S)-5-methyl-5,6,7,8-tetrahydrofolic acid, also known as (6S)-5-methylTHFA, the process comprising the steps of: (1) reducing folic acid (FA) so as to yield dihydrofolic acid (DHFA); (2) stereoselectively reducing DHFA with dihydrofolate reductase (DHFR) in the presence of NADP/NADPH, glucose and GluDH so as to yield (6S)-THFA; (3) converting (6S)-THFA to (6S)-5-methlTHFA; and (4) isolating (6S)-5-methylTHFA,12-13-2012

Patent applications by George Maguire, Newton, MA US

James Maguire, Andover, MA US

Patent application numberDescriptionPublished
20090241558COMPONENT COOLING SYSTEM - A component cooling system includes a component tank configured to receive a heat-generating device. The component tank is at least partially filled with a subcooled liquid at a first pressure and at a first temperature. A cryogenic system maintains the component tank at essentially the first temperature. The cryogenic system includes a heat exchange system thermally coupled with at least a portion of the component tank. The heat exchange system is at least partially filled with a second saturated liquid at a second pressure and at essentially the first temperature. A cryostat tank is fluidly-coupled with the heat exchange system and allows for pumpless displacement of the second saturated liquid between the heat exchange system and the cryostat tank.10-01-2009
20100071927ELECTRICAL CONNECTION STRUCTURE FOR A SUPERCONDUCTOR ELEMENT - The invention relates to an electrical connection structure for a superconductor element cooled by a cryogenic fluid and connected to an electrical bushing, which bushing passes successively through an enclosure at an intermediate temperature between ambient temperature and the temperature of the cryogenic fluid, and an enclosure at ambient temperature, said bushing projecting outside the ambient temperature enclosure. According to the invention, said intermediate enclosure is filled at least in part with a solid material of low thermal conductivity, such as a polyurethane foam or a cellular glass foam. The invention is applicable to connecting a superconductor cable at cryogenic temperature to a device for equipment at ambient temperature.03-25-2010
20100087322ELECTRICITY TRANSMISSION COOLING SYSTEM - A cooling system includes a first section of high temperature superconducting (HTS) cable configured to receive a first flow of coolant and to permit the first flow of coolant to flow therethrough. The system may further include a second section of high temperature superconducting (HTS) cable configured to receive a second flow of coolant and to permit the second flow of coolant to flow therethrough. The system may further include a cable joint configured to couple the first section of HTS cable and the second section of HTS cable. The cable joint may be in fluid communication with at least one refrigeration module and may include at least one conduit configured to permit a third flow of coolant between said cable joint and said at least one refrigeration module through a coolant line separate from said first and second sections of HTS cable. Other embodiments and implementations are also within the scope of the present disclosure.04-08-2010
20100149707Parallel Connected HTS Utility Device and Method of Using Same - A method of controlling fault currents within a utility power grid is provided. The method may include coupling a superconducting electrical path between a first and a second node within the utility power grid and coupling a non-superconducting electrical path between the first and second nodes within the utility power grid. The superconducting electrical path and the non-superconducting electrical path may be electrically connected in parallel. The superconducting electrical path may have a lower series impedance, when operated below a critical current level, than the non-superconducting electrical path. The superconducting electrical path may have a higher series impedance, when operated at or above the critical current level, than the non-superconductor electrical path.06-17-2010
20110132631FAULT CURRENT LIMITING HTS CABLE AND METHOD OF CONFIGURING SAME - A cryogenically-cooled HTS cable is configured to be included within a utility power grid having a maximum fault current that would occur in the absence of the cryogenically-cooled HTS cable. The cryogenically-cooled HTS cable includes a continuous liquid cryogen coolant path for circulating a liquid cryogen. A continuously flexible arrangement of HTS wires has an impedance characteristic that attenuates the maximum fault current by at least 10%. The continuously flexible arrangement of HTS wires is configured to allow the cryogenically-cooled HTS cable to operate, during the occurrence of a maximum fault condition, with a maximum temperature rise within the HTS wires that is low enough to prevent the formation of gas bubbles within the liquid cryogen.06-09-2011
20130065766ELECTRICITY TRANSMISSION COOLING SYSTEM - A cooling system includes a first section of high temperature superconducting (HTS) cable configured to receive a first flow of coolant and to permit the first flow of coolant to flow therethrough. The system may further include a second section of high temperature superconducting (HTS) cable configured to receive a second flow of coolant and to permit the second flow of coolant to flow therethrough. The system may further include a cable joint configured to couple the first section of HTS cable and the second section of HTS cable. The cable joint may be in fluid communication with at least one refrigeration module and may include at least one conduit configured to permit a third flow of coolant between said cable joint and said at least one refrigeration module through a coolant line separate from said first and second sections of HTS cable.03-14-2013

Patent applications by James Maguire, Andover, MA US

James F. Maguire, Andover, MA US

Patent application numberDescriptionPublished
20090247411INTERFACE DEVICE FOR A HIGH TEMPERATURE SUPERCONDUCTOR DEGAUSSING SYSTEM JUNCTION BOX - A junction box is provided which allows serial connection of the individual conductors of at least one high temperature superconductor (HTS) wire bundle. The junction box includes an electrical interface device disposed within a junction box housing. The interface device is configured receive both ends of each conductor of each HTS wire bundle, and to provide a superconductive electrical connection between respective first ends of conductors to respective second ends of other wire bundle conductors to form at least one superconductive multi-turn electromagnetic winding.10-01-2009
20090247412SUPERCONDUCTING CABLE ASSEMBLY AND METHOD OF ASSEMBLY - An HTS cable assembly is provided which includes a cryostat or housing, an HTS wire bundle disposed longitudinally within the cryostat, and plural support members disposed between the HTS wire bundle and the cryostat. The support members are elongate, tubular members having resiliency in both the axial and radial directions. The support members are disposed between the HTS wire bundle and the inner surface of the cryostat in an arrangement that maintains and supports the HTS wire bundle in a spaced-apart relationship with respect to the inner surface of the cryostat. In addition, the plural support members are configured to substantially prevent relative movement between the HTS wire bundle and the cryostat.10-01-2009

Patent applications by James F. Maguire, Andover, MA US

Mark E. Maguire, Woburn, MA US

Patent application numberDescriptionPublished
20130120421METHOD AND SYSTEM FOR MODIFYING AND RENDERING SCENES VIA DISPLAY LISTS - Various embodiments of a method and system for modifying and rendering scenes via display lists are described. Various embodiments may include a graphical application for generating a display list including display list nodes each corresponding to a respective scene element. To generate a given display list node, the graphical application may determine a scene graph node of a scene graph, allocate a portion of memory dedicated to the display list node, and store in that portion of memory, at least one of the attributes of the respective scene element determined from the particular scene graph node. The graphical application may modify a particular display list node corresponding to the particular scene element by modifying a respective attribute stored in the portion of memory allocated to the particular display list node, and render an image of a scene that includes the particular scene element modified according to the notification.05-16-2013

Martin P. Maguire, Woburn, MA US

Patent application numberDescriptionPublished
20080269217Melanocortin-4 receptor binding compounds and methods of use thereof - Provided are MC4-R binding compounds of the formula XVII:10-30-2008

Matthew R. Maguire, Cambridge, MA US

Patent application numberDescriptionPublished
20120035965SYSTEMS, METHODS, AND MACHINE-READABLE STORAGE MEDIA FOR INTERFACING WITH A COMPUTER FLIGHT SYSTEM - Provided herein are systems, methods and machine-readable media for interfacing with computer flight systems. For example, one embodiment is described wherein an unknown and/or changing inventory of aircraft, potentially including aircraft owned or operated by third parties, is managed to provide flight schedules, fare structures, and reservation inventories to computer flight systems. Another embodiment is described wherein aircraft inventory is allocated dynamically and/or adjusted in real-time in response to bookings of seats on aircraft flights in the flight schedule. Another embodiment is described wherein aircraft inventory may be changed by suppliers of aircraft, including changes to costs for using a portion of the inventory (e.g., using an aircraft for a day), and a management system may modify booking class inventories on one or more flights in the flight schedule in response.02-09-2012
20120035966SYSTEMS, METHODS, AND MACHINE-READABLE STORAGE MEDIA FOR INTERFACING WITH A COMPUTER FLIGHT SYSTEM - Provided herein are systems, methods and machine-readable media for interfacing with computer flight systems. For example, one embodiment is described wherein an unknown and/or changing inventory of aircraft, potentially including aircraft owned or operated by third parties, is managed to provide flight schedules, fare structures, and reservation inventories to computer flight systems. Another embodiment is described wherein aircraft inventory is allocated dynamically and/or adjusted in real-time in response to bookings of seats on aircraft flights in the flight schedule. Another embodiment is described wherein aircraft inventory may be changed by suppliers of aircraft, including changes to costs for using a portion of the inventory (e.g., using an aircraft for a day), and a management system may modify booking class inventories on one or more flights in the flight schedule in response.02-09-2012

Paul S. Maguire, Raynham, MA US

Patent application numberDescriptionPublished
20120265210Vertebroplasty Curved Needle - Devices, systems and methods for delivering a curable, stabilizing material into a central region of a bone structure. Precise placement of the curable substance into a central region of a bone structure through a unipedicular approach. One primary advantage is its ability to create a central cavity in a vertebral body (or to centrally deliver bone cement) through a unipedicular approach. A curved needle having increased rigidity in its flexible end when the end is disposed in its straight position. This increased rigidity is due to a novel tensioning mechanism and to a segmented tube design (as opposed to the conventional longitudinally-slotted tube design).10-18-2012
20130072941Cement Injector and Cement Injector Connectors, and Bone Cement Injector Assembly - An assembly for injecting bone cement into a vertebral body, comprising a bone cement dispenser, an introducer needle, a cement injection needle attached to the cement dispenser and slidably received in the introducer needle, and a Touhy-Borst adapter that locks and unlocks the cement injection needle from the introducer needle.03-21-2013

Stephen J. Maguire, Grafton, MA US

Patent application numberDescriptionPublished
20100052437Linear Motor With Patterned Magnet Arrays - An armature for a linear motor is described. The armature includes a first of a pair of magnetic structures comprising a first plurality of maglettes each having a magnetic polarity vector; an angle between two adjacent magnetic polarity vectors in the first plurality of maglettes having a first magnitude; and a second of the pair of magnetic structures comprising a second plurality of maglettes each having a magnetic polarity vector; an angle between two adjacent magnetic polarity vectors in the second plurality of maglettes having a second magnitude, the first plurality of maglettes including a first outer maglette that is adjacent to a second outer maglette of the second plurality of maglettes, an angle between the magnetic polarity vectors of the first and second outer maglettes having a third magnitude that is different than at least one of the first and the second magnitudes.03-04-2010
20120250875Portable Loudspeaker - A portable loudspeaker includes an electro-acoustic driver which creates sound waves when operated and a housing having a front side to which the driver is secured. The loudspeaker also includes a battery supported by the housing for providing electrical power to the driver and a cover secured to the housing which can be moved between (i) a closed position in which the cover overlies the driver, and (ii) an open position in which the cover does not overlie the driver. A controller controls operation of the loudspeaker. When the cover is moved to the closed position, a feature on the cover causes an indication to the controller that the cover is in the closed position. In response to the indication, the controller mutes the driver if the driver was outputting acoustic waves when the cover was moved to the closed position.10-04-2012
20120280579LINEAR MOVING MAGNET MOTOR COGGING FORCE RIPPLE REDUCING - A magnet structure for a linear motor. Magnet tiles of the magnet structure are arranged so that intra-pole tile gaps extend in a direction parallel to the direction of motion of the linear motor.11-08-2012

Yael Maguire, Somerville, MA US

Patent application numberDescriptionPublished
20090156427Bio-Sensing Nanodevice - The invention provides a bio-sensing nanodevice comprising: a stabilized biologically-derived G-protein coupled receptor—the olfactory receptor—on a support, a real time receptor-ligand binding detection method, an odorant delivery system and an odorant recognition program. The biologically-derived G-protein coupled receptor can be stabilized on nanotechnology using surfactant peptide. The said nanodevice provides a greater surface area for better precision and sensitivity to odorant detection. The invention further provides a microfluidic chip containing a stabilized biologically-derived G-protein coupled receptor—the olfactory receptor—immobilized on a support, and arranged in at least two dimensional microarray system. The invention also provides a method of delivering odorant comprising the step of manipulating the bubbles in complex microfluidic networks wherein the bubbles travel in a microfluidic channel carrying a variety of gas samples to a precise location on a chip. The invention further provides method of fabricating hOR17-4 olfactory receptor.06-18-2009
20110285511DUAL-FREQUENCY RFID TAG WITH ISOLATED INPUTS - An Integrated Circuit (IC) for an RFID tag includes two electrically isolated antenna ports for connecting to two antennas, with each antenna port configured to operate at a different frequency range and/or with a different communications protocol. In some embodiments a rectifier coupled to one of the antenna ports is operable to extract energy from an electromagnetic field in a first frequency range, and a demodulator coupled to the other antenna port is operable to demodulate symbols according to an RFID protocol in a second frequency range. In some embodiments the frequency ranges are disjoint, intersecting, or one is a proper subset of the other. In some embodiments each port is coupled to its own rectifier and/or its own modulator and/or its own demodulator. In some embodiments an RFID tag includes the IC and two antennas, each operable in one of the two frequency ranges.11-24-2011
20120215470AC PLUG RECEPTACLE WITH NON-CONTACT POWER METER AND RADIO TELEMETRY - A power measurement device in accordance with aspects of the invention comprises a power harvesting unit that extracts a fraction of current flowing through an electric power supply unit to an electronic appliance; a power determination circuit that generates power measurement data indicative of at least one of the extracted current or a power consumed by the electronic appliance determined based on the extracted current; and an output device that outputs the power measurement data. The power measurement device can be used with plugs or sockets as an external component or integrated therein as an internal component.08-23-2012
20120309295PASSIVELY POWERING A WIRELESS COMMUNICATIONS DEVICE - A wireless device includes an RF interface, logic circuitry, power circuitry, an impedance matching transformer, and a transducer. The RF interface is configured to receive an RF signal and provide an output data signal derived from the RF signal. The logic circuitry is configured to receive the output data signal and provide an output analog signal. The power circuitry is coupled to the RF interface and configured to provide DC operating power derived from the RF signal to the RF interface and the logic circuitry. The impedance matching transformer has an input coupled to the logic circuitry and an output. The transducer is coupled to the output of the impedance matching transformer and is configured to produce an audio signal based on the output analog signal.12-06-2012
20120309453DUAL MODE WIRELESS COMMUNICATIONS DEVICE - A wireless communications device includes a battery, a processing section coupled to the battery, and an RF interface. The battery is configured to provide power to operate the wireless communications device in a first mode of operation. The processing section is configured to operate on battery power in the first mode of operation. The RF interface is configured to receive an RF signal and generate operating power for the wireless communication device from the RF signal in a second mode of operation. The wireless communications device is configured to detect available RF power and enter the second mode of operation from the first mode of operation.12-06-2012
20120309454METHODS AND DEVICES FOR IDENTIFYING SELECTED OBJECTS - A method of choosing an object from multiple objects using a wireless device includes receiving a backscatter communication signal from each of the objects, determining one or more analog parameter of each backscatter communication signal, and, using the wireless device, selecting one object based at least in part on the analog parameter of each backscatter communication signal. Each of the objects includes an RF interface configured to communicate using backscatter communication.12-06-2012

Patent applications by Yael Maguire, Somerville, MA US

Yael Maguire, Boston, MA US

Patent application numberDescriptionPublished
20130080092SYSTEMS AND METHODS FOR DATA COMPRESSION AND FEATURE EXTRACTION FOR THE PURPOSE OF DISAGGREGATING LOADS ON AN ELECTRICAL NETWORK - Some embodiments concern a method of detecting usage of one or more electrical devices coupled to an electrical power line. An electrical power signal with a predetermined period is on the electrical power line. The one or more electrical devices place one or more noise signals on the electrical power line. The electrical power signal comprises the one or more noise signals. The method can include: using a data acquisition device to acquire first data about the electrical power signal on the electrical power line such that the acquiring of the first data is synchronized with the predetermined period of the electrical power signal; processing the first data to create frequency domain data; and applying a feature extraction algorithm to the frequency domain data to determine a transition of an electrical state of at least a first one of the one or more electrical devices. Other embodiments are disclosed.03-28-2013

Yael G. Maguire, Cambridge, MA US

Patent application numberDescriptionPublished
20110148591METHODS AND APPARATUS FOR OPERATING A RADIO DEVICE - A radio device such as a wireless tag reader communicates with multiple types of wireless identification tags in a monitored region. The radio device includes a network interface to receive messages transmitted over a network. In response to receiving a message indicating to reconfigure the radio device to support an additional wireless tag protocol, the radio is reconfigured to support communications with a corresponding new type of wireless identification tag in a monitored region. Based on this technique of reconfiguring the radio device via network messages, the radio device optionally supports additional, new or latest versions of wireless tag protocols without having to physically reprogram or replace the radio device.06-23-2011

Yael G. Maguire, Somerville, MA US

Patent application numberDescriptionPublished
20100069011Methods and Apparatus For Self-Jamming Suppression In A Radio Frequency Identification (RFID) Reader - A circuit for transmitter-receiver isolation that is useful in a monostatic (combined transmitting and receiving) antenna configuration is shown and described. In addition, methods and systems are shown for automatically adjusting the circuit in response to changes in antenna configuration, external signal reflectors, and jamming energy (e.g., self jammer energy) by adjusting the circuit to tune out these sources of jammer energy to yield an increase in RFID reader receiver sensitivity when compared to measurements of the receiver sensitivity when the jammer energy is not present.03-18-2010
20100109844Methods and Apparatuses For RFID Tag Range Determination - Apparatus and methods are described which are useful for determining a location characteristic between an RFID tag and an RFID tag reader or a second RFID tag. In various embodiments, signals backscattered from a singulated tag over a range of frequencies are evaluated for in-phase I and in-quadrature Q signal components. The I-Q data is processed to determine phase delay angles associated with each signal frequency. The phase delay data can be processed by a sum of squared errors method or Fourier transform method to determine a distance to the singulated tag. The methods can also be used to determine any of a location, a radial velocity, a directional velocity of the singulated tag, and proximity of the singulated tag to a second tag.05-06-2010
20100137024Multi-Mode Radio Frequency Communications - A transceiver circuit includes an input to receive an RF mode control signal, multiple ports, and path circuitry disposed between the multiple ports. The path circuitry can be configured to create different low impedance conductive paths between the multiple ports depending on a state of the RF mode control signal. For example, depending on a mode as specified by the RF mode control signal, the transceiver circuit and corresponding path circuitry enables a half-duplex mode and a full-duplex mode.06-03-2010

Yael G. Maguire, Boston, MA US

Patent application numberDescriptionPublished
20120307875Mobile Communications Devices and Methods Having Reduced Communication Latency - An improved mobile communications device, of the type having a set of antennas and a narrowband RF transceiver coupled to a first member of the set of antennas, also includes a broadband RF receiver coupled to a second member of the set of antennas; and processing circuitry, coupled to the narrowband RF transceiver and the broadband RF receiver, that uses a received signal from the broadband receiver to determine a communication parameter for the narrowband RF transceiver. Related methods are also provided.12-06-2012
20120309326Switchable Antenna Elements for a Wireless Communications Device - A wireless communications device includes multiple switchable antenna elements that may be used to improve interfacing of the wireless communications device with other devices, such as for interfacing of an RFID-equipped mobile communications device with other RFID devices (e.g., to better ensure power delivery to and/or communication with such other RFID devices) and/or may be used to characterize various aspects of the environment around the wireless communications device, such as for proximity-based functionality.12-06-2012

Yael Gregory Maguire, Somerville, MA US

Patent application numberDescriptionPublished
20100148931RADIO DEVICES AND COMMUNICATIONS - Each of multiple radio devices in a region (e.g., a zone) receives time reference information for synchronizing themselves amongst each other. For example, based on the timing reference information, each radio device in a region synchronizes itself with respect to a common time reference, enabling communications according to shared access schedule (e.g., a time slotted access schedule). Each of the radio devices schedules communications to one or more target devices (e.g., RFID tags) in a monitored region based at least in part according to the shared access schedule. For example, each of multiple transmitters of the tag readers are assigned one or more time slots of the shared access schedule in which they are permitted to communicate in the monitored region.06-17-2010