Maclaughlin
Christina M. Maclaughlin, Toronto CA
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20130273561 | LIPID ENCAPSULATION OF SURFACE ENHANCED RAMAN SCATTERING (SERS) NANOPARTICLES - Phospholipid-microvesicle-encapsulated surface enhanced Raman scattering (SERS) nanoparticles and methods for making the encapsulated particles are described. The encapsulated particles can be used in nanomedicine. Four Raman-active species were used. A bilayer was observed by TEM, and the SERS spectrum of each dye species (SERS reporter) was confirmed. | 10-17-2013 |
David T. Maclaughlin, Gloucester, MA US
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20100273160 | METHODS TO IDENTIFY AND ENRICH FOR POPULATIONS OF OVARIAN CANCER STEM CELLS AND SOMATIC OVARIAN STEM CELLS AND USES THEREOF - The present invention relates to compositions and methods for treating, characterizing and diagnosing ovarian cancer. In particular, the present invention provides methods for treating and/or preventing ovarian cancer in a subject by administering to the subject an effective amount of Mullerian Inhibiting substance and/or an effective amount of an agent that inhibits BCRP1. The present invention further provides methods to identify and/or enrich for populations of ovarian cancer stem cells and populations of somatic ovarian stem cells, in particular, enrichment for populations of coelomic somatic ovarian stem cells, subcoelomic/stromal somatic ovarian stem cells and periphilar medullary somatic ovarian stem cells. The present invention also provides somatic ovarian stem cell markers and ovarian cancer stem cell markers, as well as methods to identify agents which selectively inhibit the proliferation of ovarian cancer stem cells as compared to somatic ovarian stem cells. | 10-28-2010 |
20140194366 | OVARIAN CANCER STEM CELLS AND METHODS OF ISOLATION AND USES THEREOF - The present invention generally relates to methods, assays, compositions and kits related to a subpopulation of ovarian cancer stem cells which are selected or enriched by chemotherapeutic agents and inhibited by MIS (Mullerian Inhibiting Substance) and MIS mimetics. In particular, the present invention relates to a population of CD44+/CD24+/EpCam+/ECad− subpopulation of ovarian cancer stem cells. The present invention also provides methods to screen a subject with ovarian cancer to identify if they have an ovarian cancer comprising CD44+/CD24+/EpCam+/ECad− ovarian cancer stem cells, and methods to identify and enrich or isolate for such ovarian cancer cell populations. | 07-10-2014 |
Edwin J. Maclaughlin, Hermosa Beach, CA US
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20120330854 | DISTRIBUTABLE REFERRAL DIRECTORY - A user-content generated network is provided for presenting business listings, as well as commentary and reviews of businesses, by participants of the network. In an embodiment, businesses can participate in the network and receive referrals from members of the network. The network can track and monitor referrals that individual businesses receive as a mechanism for promoting the business to other users in the network's user base. | 12-27-2012 |
Edwin John Maclaughlin, Manhattan Beach, CA US
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20100287282 | SYSTEM AND METHOD FOR PROVIDING A REFERRAL NETWORK IN A SOCIAL NETWORKING ENVIRONMENT - A user-content generated network is provided for presenting business listings, as well as commentary and reviews of businesses, by participants of the network. In an embodiment, businesses can participate in the network and receive referrals from members of the network. The network can track and monitor referrals that individual businesses receive as a mechanism for promoting the business to other users in the network's user base. | 11-11-2010 |
Fiona Maclaughlin, Belfast IE
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20090209630 | GENE DELIVERY FORMULATIONS AND METHODS FOR TREATMENT OF ISCHEMIC CONDITIONS - The present inventors have developed a novel approach for efficient delivery of angiogenic factors to the cardiac and peripheral vasculature that avoids problems with toxicity inherent to existing delivery technologies. Vectors carrying coding sequences for angiogenic agents including Del-1 or VEGF, or both, can be formulated with poloxamers or other polymers for delivery into ischemic tissue and delivered to areas of peripheral ischemia in a flow to no-flow pattern and to the heart by retrograde venous perfusion. | 08-20-2009 |
Kevin Maclaughlin, Yongin-Si KR
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20150112551 | FRICTION COMPENSATION LOGIC OF MOTOR DRIVEN POWER STEERING AND METHOD THEREOF - Exemplary embodiments of the present invention relate to a friction compensation logic of MDPS and a friction compensation method using the same. The friction compensation logic of MDPS in accordance with an embodiment of the present invention includes: a signal processor configured to extract only a signal having a limited range from column torque signals input from a column torque; a friction compensation sign calculator configured to determine a friction compensation sign by integrating the column torque signal extracted by the signal processor and calculating the friction compensation sign by limiting the integrated value to a set value; and a friction compensation torque calculator configured to calculate a friction compensation torque by reflecting a friction compensation amount to a value calculated by the friction compensation sign calculator. | 04-23-2015 |
Scott Maclaughlin, Windsor, CO US
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20110074342 | WIRELESS ELECTRICITY FOR ELECTRONIC DEVICES - A system and method for the wirelessly charging electronic devices. For example, the electronic device may be a pulse oximeter with a wireless sensor. The wireless sensor may include a sensor power source adapted to power the wireless sensor. The wireless sensor may also include a sensor charging device adapted to receive a wireless electromagnetic charging signal and charge the power source via the wireless electromagnetic charging signal. | 03-31-2011 |
20110245640 | Films For Touchscreen Displays Of Medical Device Monitors - According to various embodiments, a medical device monitor includes a touchscreen and a film disposed on an external surface of the touchscreen. The film resists formation of visible fingerprints and resists growth of microorganisms. In various embodiments, one layer or more than one layer of the film may be disposed on the touchscreen. | 10-06-2011 |
20110245641 | Monitor With Multi-Position Base - According to various embodiments, a medical monitoring device includes a monitor component and a base component. The base component has one or more connectors on a facing of the base component. The monitor component is capable of rotating with respect to the base component. In various embodiments, the monitor component may be above the base component. | 10-06-2011 |
Scott Maclaughlin, Boulder, CO US
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20100249553 | Electroadhesive Medical Devices - A method and system for attaching medical devices to a patient are provided. In accordance with an embodiment, a medical device is formed with or is coupled to an attachment structure including a plurality of electrodes capable of generating differential voltages at adjacent electrodes, to thereby provide electrostatic adhesion with the tissue of a patient. In an embodiment, the attachment structure includes an insulative material between the respective electrodes of the plurality of electrodes. | 09-30-2010 |
20100331631 | OXYGEN SATURATION EAR SENSOR DESIGN THAT OPTIMIZES BOTH ATTACHMENT METHOD AND SIGNAL QUALITY - A system is provided that includes an ear sensor and an external device. The ear sensor includes a sensing component with sensors for sensing various physiological parameters. The ear sensor also includes a retaining component configured to retain the ear sensor to the ear of a wearer. As the retaining component retains the ear sensor to the ear, the sensing component may be configured to have an optimal surface contact between the sensors and the ear tissue, such that an improved physiological signal may be obtained. In some embodiments, the improved physiological signal may result in physiological data, which may be displayed and organized in the external device. | 12-30-2010 |
Shane A. Maclaughlin, New South Wales AU
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20150024925 | PROTECTIVE COATING COMPOSITIONS FOR PHOTOCATALYTIC LAYERS ON SUBSTRATES - A coated substrate including a substrate including a treated layer, a photocatalytic layer, and a protective layer for impeding photocatalyst derived degradation of the treated layer, the protective layer being provided between the photocatalytic layer and the treated layer, the protective layer comprising colloidal particles distributed in a matrix comprised at least partly of an organosilicon phase which is oxidisable by the reactive oxygen species to form a non-volatile inorganic phase, wherein the organosilicon phase includes a surfactant incorporating an organosilicon component. | 01-22-2015 |
20150072136 | PROTECTIVE BARRIER COMPOSITION FOR PHOTOCATALYTIC COATINGS - A coated substrate including: a substrate including a treated layer, a photocatalytic layer, and a protective layer between the photocatalytic layer and the treated layer, the protective layer comprising colloidal particles dispersed in a matrix, the colloidal particles including first and second types of particles that differ in their respective particle size distributions and which together provide a physical barrier by virtue of the first, smaller particles at least partially filling interstices between the second, larger particles and thereby impede photocatalyst derived degradation of the treated layer, the first type of colloid particles comprising hydrolysed silica based material such as reactive silica condensate particles or polyhedral oligomeric silsesquioxanes, or mixtures thereof, the protective layer having an effect of less than 20 delta E units on the colour and gloss of the substrate. | 03-12-2015 |
Victor James Maclaughlin, Richmond, VA US
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20090156279 | System and method for competition between teams - The invention is a method and system for providing a game in which different teams/companies compete to determine which team/company can generate the most income in a selected period of time, such as one year. Teams are formed of multiple players, with each player providing a player fee in the form of money or other valuable assets (e.g., ideas, expertise, etc.). Multiple teams form the game, which is overseen by a controlling organization. The game may be broadcast, as a television or web-based broadcast, and may include one or more websites to provide information to the public (either free or for a fee) on the overall game and/or individual team developments. | 06-18-2009 |