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Ma, US

Angie H. Ma, Newark, DE US

Patent application numberDescriptionPublished
20090253832COLORANT COMPATIBLE HYDROPHOBICALLY MODIFIED POLYURETHANE THICKENER FOR PAINT - A synthetic polymer has a water-soluble or water-swellable polyurethane backbone and terminal groups and/or intermediate groups of blocks of hydrophobes of alkyl- or aryl compounds containing a polymerizable cyclic monomer or a polymerizable double bond (or alkene) group or derivatives thereof. The blocks of hydrophobes are composed of two or more units of the same or different hydrophobes. These synthetic polymers are used as rheology modifiers, especially in latex paints.10-08-2009
20100324177COLORANT COMPATIBLE HYDROPHOBICALLY MODIFIED POLYETHYLENEGLYCOL THICKENER FOR PAINT - A synthetic polymer has a water-soluble or water-swellable polyethyleneglycol backbone and terminal groups and/or intermediate groups of blocks of hydrophobes of alkyl- or aryl compounds containing a polymerizable cyclic monomer or a polymerizable double bond (or alkene) group or derivatives thereof. The blocks of hydrophobes are composed of two or more units of the same or different hydrophobes. These synthetic polymers are used as rheology modifiers, especially in latex paints.12-23-2010

Patent applications by Angie H. Ma, Newark, DE US

Ben-Jiang Ma, Durham, NC US

Patent application numberDescriptionPublished
20100316672VACCINE - The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to HIV-I envelope (Env) immunogens.12-16-2010

Changbao Ma, Fairfax, VA US

Patent application numberDescriptionPublished
20110317960DIRECT COUPLING OF OPTICAL SLOT WAVEGUIDE TO ANOTHER OPTICAL WAVEGUIDE - Devices, systems and techniques for directly coupling an optical slot waveguide to another optical waveguide without a taper waveguide region between the two optical waveguides.12-29-2011

Changbao Ma, Arlington, VA US

Patent application numberDescriptionPublished
20100119194Optical Waveguide With Reflector - An optical waveguide includes a core layer having a first core section and a second core section, wherein the first core section is non-axially aligned with the second core section. The optical waveguide also includes a cladding layer disposed about the core layer and a reflector in optical communication with the core layer for directing an electromagnetic wave from the first core section to the second core section.05-13-2010

Chun C. Ma, Ballwin, MO US

Patent application numberDescriptionPublished
20120002404Holiday lantern carrier - An illuminated candy or other merchandise bucket or carrier is provided for use by children on Halloween, or other holidays. The structure of the bucket is a double-layered or walled carrier, with LED light, or other illuminated source, established between the layered inner and outer walls for the formed carrier.01-05-2012

Daiping Ma, Wilmington, NC US

Patent application numberDescriptionPublished
20110305420MULTIMODE FIBER OPTIC ASSEMBLIES - Fiber optic assemblies including at least one multimode optical fiber that have improved performance are disclosed. In one embodiment, at least one connector is mounted upon and end of at least one multimode optical fiber and the assembly has an insertion loss of about 0.04 dB or less at a reference wavelength of 850 nanometers. Another embodiment is directed to a fiber optic assembly having a plurality of multimode optical fibers attached to a multifiber ferrule. The multifiber ferrule has a pair of guide pin bores having a nominal diameter, wherein the guide pin bores have a tolerance of ±0.0005 millimeters from a nominal diameter for improving performance.12-15-2011

Dou Ma US

Patent application numberDescriptionPublished
20110271274SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR COLLABORATIVELY INSTALLING A COMPUTER APPLICATION - According to one embodiment, a computer program product for collaboratively installing a computer application includes a computer readable storage medium having computer readable program code embodied therewith, the computer readable program code including computer readable program code configured to: monitor an installation process of an application, send a remote assistance request in response to a determination that the installation process requires remote assistance, receive a response to the remote assistance request, and continue the installation process of the application using the remote assistance information. The response includes remote assistance information required for installing the application, and the remote assistance information is invisible to an installer of the application. In other embodiments, and a method for collaboratively installing a computer application includes operations for performing the above described processes, and a system includes modules for performing the above described processes.11-03-2011

Frank M. S. Ma, Charleston, WV US

Patent application numberDescriptionPublished
20110306477CLOSED LOOP DEVICE INCORPORATING ONE OR MORE INDECOMPOSABLE KNOTS AND METHODS OF USING - A flexible, closed loop device that includes at least one indecomposable knot formed that helps define a plurality of adjustable loops. The knot can be easily loosened so that the loop sizes can be adjusted. The knot is easily tightened and locked. In some embodiments, the device includes at least two indecomposable knots. The device is useful in the practice of yoga, Pilates, and other personal training exercises. The device is flexible and easily adjustable, allowing the user to more effectively target specific muscle groups. The device may additionally or alternately be used as a securing and carrying strap for items. Still further, the device may be used as a connecting device to link items together for towing, hoisting, etc.12-15-2011

Hai-Ping Ma, Lincoln, RI US

Patent application numberDescriptionPublished
20090081061PERIPHERALLY PIVOTED OSCILLATING VANE MACHINE - The present invention is directed to a peripherally pivoted oscillating vane machine (OVM). The OVM has been optimized for performance and efficiency. This has been accomplished by reducing loads on the drive mechanism and by employing de-phased motion of the peripherally pivoted vanes in conjunction with improved porting configurations as well as valve actuation and manufacture.03-26-2009

Hung-Piao Ma, Portland, OR US

Patent application numberDescriptionPublished
20090089607Systems and methods for voltage regulator communication - Systems and method for providing a regulated voltage supply to an integrated circuit. In an embodiment of the invention, a voltage regulator in a system provides an integrated circuit in the system with information related to the voltage regulator providing a supply voltage to the integrated circuit. In another embodiment of the invention, the integrated circuit makes determinations about the operating characteristic of the system using information from the voltage regulator.04-02-2009
20090167092SIMULTANEOUS MULTI-VOLTAGE RAIL VOLTAGE REGULATION MESSAGES - Methods and mechanisms to simultaneously regulate two or more supply voltages provided to an integrated circuit by a voltage regulator. In an embodiment of the invention, a voltage regulation message exchanged between the integrated circuit and the voltage regulator includes an identifier indicating two or more supply voltages selected from a plurality of supply voltages provided to the integrated circuit by the voltage regulator, where the voltage regulation message relates to the indicated two or more supply voltages. In another embodiment, the voltage regulation message indicates a desired supply voltage level to which the indicated two or more supply voltages are to transition.07-02-2009
20110199153Simultaneous Multi-Voltage Rail Voltage Regulation Messages - Methods and mechanisms to simultaneously regulate two or more supply voltages provided to an integrated circuit by a voltage regulator. In an embodiment of the invention, a voltage regulation message exchanged between the integrated circuit and the voltage regulator includes an identifier indicating two or more supply voltages selected from a plurality of supply voltages provided to the integrated circuit by the voltage regulator, where the voltage regulation message relates to the indicated two or more supply voltages. In another embodiment, the voltage regulation message indicates a desired supply voltage level to which the indicated two or more supply voltages are to transition.08-18-2011

Patent applications by Hung-Piao Ma, Portland, OR US

Jiyan Ma, Columbus, OH US

Patent application numberDescriptionPublished
20110183421COMPOSITION AND METHOD FOR CONVERTING A NON-PATHOGENIC PRION PROTEIN INTO A PATHOGENIC CONFORMATION AND USES THEREOF - Described herein is a composition for converting a non-pathogenic prion protein (“PrP07-28-2011

Joseph Ma US

Patent application numberDescriptionPublished
20090168426Optical device for adjusting the F-number of an elliptical lamp - An optical device for effectively adjusting the F-number of an elliptical lamp is provided, the elliptical lamp for producing a focussed light beam at a given focal point having a given cone angle. The optical device comprises a light interaction portion for optically interacting with the focussed light beam when the light interaction portion is in general longitudinal alignment with a light emitting aperture of the elliptical lamp, the light interaction portion for triggering optical adjustment of a cone angle of at least a high cone angle portion of the focussed light beam to a smaller cone angle. The optical device further comprises a light egress portion, coupled to the light interaction portion, for enabling exit of the focussed light beam from the optical device with an effective cone angle smaller than the given cone angle, after the cone angle of the at least the high cone angle portion of the focussed light beam has been adjusted to the smaller cone angle.07-02-2009

Jun F. Ma, Greenville, SC US

Patent application numberDescriptionPublished
20090071118METHOD AND SYSTEM FOR MODULATING THE MODIFIED WOBBE INDEX OF A FUEL - A method and system for modulating the Modified Wobbe Index (MWI) of a fuel is provided. A variety of industrial components, which may require a gas fuel, such as but not limiting of, a heavy-duty gas turbine; an aero-derivative gas turbine; or a boiler may utilize the method and system. The method and system may provide an industrial component comprising at least one steam injection system, wherein the at least one steam injection system injects steam into at least one fuel supply line upstream of a combustion system to modulate the MWI of at least one fuel. The method and system may also determine whether the MWI of the at least one fuel is outside of a predetermined range; and utilize the at least one steam injection system to automatically inject the steam at a flowrate for adjusting the MWI of the at least one fuel.03-19-2009

Keith Ma US

Patent application numberDescriptionPublished
20090089303Method and apparatus for transmission and storage of digital medical data - System for decentralized storage and rapid retrieval of medical data among geographically separate locations, connected by data paths of limited bandwidth, which optimizes transmission therebetween. Medical data is separated into bulk content and metadata. Metadata is transmitted to all locations. Bulk content is copied to selected locations based on desired duplication, available storage, distance, transmission cost, data path bandwidth or utilization, likelihood of retrieval calculated from the metadata, requests to use or prior usage of content or information from a system that manages the content. Transmission rate is limited and bulk content is queued for transmission based on priority calculated from metadata, from requests to use content or information from a system that manages the content. Optimal locations for bulk content are recalculated based on requests to use content, new patient appointments, data path or equipment failures. Copies are made or deleted. Distributed lists of locations for content are updated.04-02-2009

Kevin Ma, Nashua, NH US

Patent application numberDescriptionPublished
20110283134Server Checking Using Health Probe Chaining - A load balancer sends a probe packet to a first server in a list of servers. Each server in the list sends the probe successively down the list of servers and acknowledges the probe if the server is healthy. The final server in the list sends a signal to the load balancer to indicate that the chain of server probing has completed successfully. In this manner, the load balancer (or other device performing the checking) only needs to send a single probe rather than probe each server in the list separately. Embodiments include serial and recursive acknowledgments from the servers, sending a beacon message upon failure, and other features.11-17-2011

Kevin J. Ma, Nashua, NH US

Patent application numberDescriptionPublished
20110191414METHOD AND APPARATUS FOR EFFICIENT HTTP STREAMING - A method and apparatus provide streaming delivery of data such as media data (video, audio) using a non-streaming delivery mechanism such as HTTP along with server-side pacing of the delivery. An initial portion of the media data is preloaded to a client buffer in a bursting manner to minimize latency. The method may include client request verification, support for client self-pacing, and support for catch-up pacing reductions. A proxy server apparatus may also be used which employs both server-side and client-side pacing and may include caching and both cache and client preloading for minimized latency. A similar proxy server apparatus may be used to provide an efficient alternative to client polling for data from a polled data service, such as stock quotes etc., using streaming updates. The method may include support for stream modification through persistent client requests.08-04-2011
20120002717METHOD AND SYSTEM FOR LIVE STREAMING VIDEO WITH DYNAMIC RATE ADAPTATION - A live streaming system/method provides cross platform live streaming capabilities to mobile devices. A file format compatible with legacy HTTP infrastructure is used to deliver media over a persistent connection. Legacy client media players can dynamically change the encoded rate of the media delivered over a persistent connection. Standard HTTP servers may be used without modification, leveraging standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations.01-05-2012
20120004960METHOD AND SYSTEM FOR EFFICIENT STREAMING VIDEO DYNAMIC RATE ADAPTATION - A streaming media system employs dynamic rate adaptation. The method includes a file format compatible with legacy HTTP infrastructure to deliver media over a persistent connection. The method further includes the ability for legacy client media players to dynamically change the encoded delivery rate of the media over a persistent connection. The method provided works transparently with standard HTTP servers, requiring no modification and leverages standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations. A system is also specified for implementing a client and server in accordance with the method.01-05-2012
20120005364SYSTEM AND METHOD FOR NETWORK AWARE ADAPTIVE STREAMING FOR NOMADIC ENDPOINTS - In a system for streaming data over a network, the type and rate of streaming are automatically varied based on available network bandwidth. Video media is transcoded into different bit rate encodings that are divided into segment files. Segments are sent from a network-aware adaptive streaming (NAAS) server and reassembled and presented to a media player at a client device. The system may download additional segment files ahead of time from multiple NAAS servers to increase throughput. A playback status (“bookmark”) may be maintained to keep track of what the user has viewed and to allow the user to continue playing from where the user left off. The user may continue watching from the bookmark point on the same device or on a different device.01-05-2012
20120005365METHOD AND SYSTEM FOR EFFICIENT STREAMING VIDEO DYNAMIC RATE ADAPTATION - A streaming media system employs dynamic rate adaptation. The method includes a file format compatible with legacy HTTP infrastructure to deliver media over a persistent connection. The method further includes the ability for legacy client media players to dynamically change the encoded delivery rate of the media over a persistent connection. The method provided works transparently with standard HTTP servers, requiring no modification and leverages standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations. A system is also specified for implementing a client and server in accordance with the method.01-05-2012
20120005366METHOD AND APPARATUS FOR RETRIEVING AND RENDERING LIVE STREAMING DATA - A live streaming system/method provides cross platform live streaming capabilities to mobile devices. A file format compatible with legacy HTTP infrastructure is used to deliver media over a persistent connection. Legacy client media players can dynamically change the encoded rate of the media delivered over a persistent connection. Standard HTTP servers may be used without modification, leveraging standard media players embedded in mobile devices for seamless media delivery over wireless networks with high bandwidth fluctuations.01-05-2012
20120011267LIVE STREAMING MEDIA DELIVERY FOR MOBILE AUDIENCES - A live streaming system/method provides cross platform live streaming capabilities to mobile devices. The live streaming system includes a live streaming recorder operative to (1) capture a live media stream generated by a live media source and save the captured live media stream as a recorded stream in a recorded media file, and (2) transcode the recorded stream into a plurality of transcoded media files of respective different media encoding formats. The system further includes a stream distribution subsystem operative to generate a plurality of distributed media streams each generated from one or more of the transcoded media files, each distributed media stream being delivered to a corresponding set of the mobile endpoint devices.01-12-2012

Linda L. Ma, Las Vegas, NV US

Patent application numberDescriptionPublished
20110203602DELINEATING NAIL FOR NAIL TREATMENT APPLICATIONS AND METHOD THEREFOR - A delineating nail for creating quick, consistent, and high quality nail treatments is disclosed herein. The delineating nail may have a substrate with a base end and a tip end. A guide of various configurations may extend from the substrate at the base end. The delineating nail may be attached to a natural nail such as with one or more adhesives. One or more decorative coatings may then be applied to the substrate, natural nail, or both. The guide may shape the decorative coatings to produce various designs on the natural nail. In this manner, the delineating nail may be used by nail technicians of virtually any skill level. With the delineating nail, even inexperienced technicians can provide consistent and high quality nail treatments in a rapid manner.08-25-2011

Liping Ma US

Patent application numberDescriptionPublished
20110140093COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES - Compounds including optionally substituted Ring Systems 1-4 may be used as hosts in light-emitting devices.06-16-2011

Liqing Ma, Fairlawn, OH US

Patent application numberDescriptionPublished
20110240197PNEUMATIC TIRE AND RUBBER COMPOSITION CONTAINING TWIN POLYMERIZATION STRUCTURES - The present invention is directed to a pneumatic tire comprising a component, the component comprising a rubber composition comprising a diene based elastomer and 1 to 100 phr of: 10-06-2011

Liyuan Ma, Orlando, FL US

Patent application numberDescriptionPublished
20110195526Thermo-probes, methods of making thermo-probes, and methods of detection using thermo-probes - Embodiments of the present disclosure provide for thermo-probes (also referred to herein as “probes”), particles including a plurality of probes, methods of making thermo-probes or particles, thermo-probe complexes, method of making thermo-probe complexes, methods of detecting a target, methods of detecting multiple targets, assays using the thermo-probes, immunoassays using the thermo-probes, methods of using thermo-probes or particles, and the like.08-11-2011

O.john Ma, Portland, OR US

Patent application numberDescriptionPublished
20080293029Ultrasound Training Mannequin - The ultrasound training mannequin (11-27-2008

Teng Ma, Tallahassee, FL US

Patent application numberDescriptionPublished
20110229970DUAL-CHAMBER PERFUSION BIOREACTOR FOR ORTHOPEDIC TISSUE INTERFACES AND METHODS OF USE - The subject invention concerns a perfusion bioreactor device and methods of using the same. A bioreactor device of the invention can be used to grow cells and tissue in a controlled in vitro environment. A perfusion bioreactor device of the invention can have multiple perfusion chambers that can be controlled individually. Transverse or parallel flow of a fluid can be provided to each chamber. Cells can be seeded on a hydrogel and/or 3D scaffold to provide a 3D environment in the bioreactor device where the cells can adhere, proliferate, migrate, secrete growth and/or differentiation factors, and/or undergo differentiation, etc. The subject invention also concerns hydrogels and 3D scaffolds that can be used to grow and/or differentiate cells thereon.09-22-2011
20120020934MATERIALS AND METHODS FOR CRYOPRESERVED BONE CONSTRUCTS - The subject invention concern materials and methods for cryopreservation of HCG-cell constructs. In one embodiment, porous HCG scaffolds are provided in a perfusion bioreactor having perfusion chambers that can contain the HCG scaffolds, cells are then seeded in the HCG scaffolds in the perfusion bioreactor, cell culture media is perfused through and the bioreactor operated so as to allow for cell seeding and growth in the HCG scaffold. After a suitable period of time, the cell culture media is removed and the HCG containing cells (HCG-cell constructs) can be washed with a suitable buffer, such as phosphate-buffered saline (PBS). The HCG-cell constructs are then perfused in the bioreactor with a suitable cryopreservation fluid. The cryopreservant can comprise one or more of the following: DMSO, trehalose, glycerol, ethylene glycol, and serum for cell culture (e.g., fetal bovine serum (FBS)). In one embodiment, the HCG-cell constructs are perfused for a suitable period of time with cryopreservant fluid using transverse flow of the fluid in the bioreactor at a suitable flow rate. The HCG-cell constructs (or the perfusion chambers containing them) are then removed from the bioreactor and placed in a cryopreservant media and maintained at increasingly colder temperatures until temperatures reach about −80° C. The frozen HCG-cell constructs (or the chambers containing them) can then be stored at a suitable cryogenic temperature (e.g., in liquid nitrogen) until needed. When needed, frozen HCG-cell constructs can be removed from cold storage and thawed using suitable means (e.g., 37° C. water bath). Cells contemplated for use in the present invention include stem cells, such mesenchymal stem cells. Cells can be animal cells, such as mammalian cells. In one embodiment, the cells are human cells.01-26-2012

Wanlong Ma US

Patent application numberDescriptionPublished
20110269162UBIQUITIN PROTEASOME SYSTEM PROFILING FOR DIAGNOSIS OF CHRONIC LIVER DISEASE - Provided herein are methods for the diagnosis, staging, prognosis, or management of liver disease, e.g. chronic liver disease, and other diseases using profiles of the ubiquitin-proteasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of patients with liver disease.11-03-2011

Wanran Ma, Boulder, CO US

Patent application numberDescriptionPublished
20120029304CONFIGURABLE PATIENT MONITORING SYSTEM - A patient monitoring system is provided which includes a platform and one or more monitoring modules. Monitoring modules include parameter modules for monitoring physiological activity of a patient, and utility modules for providing additional functionality to the patient monitoring system. A platform and one or more monitoring modules may be coupled to form a communications bus, allowing communication between any of the plurality of coupled devices. Updates such as software upgrades may be provided by a monitoring module to a platform or other monitoring module to update functionality.02-02-2012

Xiaochao Ma, Bethesda, MD US

Patent application numberDescriptionPublished
20110055943NOVEL THERAPEUTIC TARGETS IN INFLAMMATORY BOWEL DISEASE - The present invention relates to novel sequences for use in detection, diagnosis and treatment of bowl disease (BD). The invention provides BD-associated polynucleotide sequences whose expression is associated with BD. Provided herein are diagnostic compositions and methods for the detection of BD. The present invention provides monoclonal and polyclonal antibodies specific for the BD polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of BD.03-03-2011

Xiaoli Ma, Auburn, AL US

Patent application numberDescriptionPublished
20110255572ESTIMATING FREQUENCY-OFFSETS AND MULTI-ANTENNA CHANNELS IN MIMO OFDM SYSTEMS - Techniques are described for carrier frequency offset (CFO) and channel estimation of orthogonal frequency division multiplexing (OFDM) transmissions over multiple-input multiple-output (MIMO) frequency-selective fading channels. A wireless transmitter forms blocks of symbols by inserting training symbols within two or more blocks of information-bearing symbols. The transmitter applies a hopping code to each of the blocks of symbols to insert a null subcarrier at a different position within each of the blocks of symbols, and a modulator outputs a wireless signal in accordance with the blocks of symbols. A receiver receives the wireless signal and estimates the CFO, and outputs a stream of estimated symbols based on the estimated CFO.10-20-2011

Yanguo Ma, Salt Lake City, UT US

Patent application numberDescriptionPublished
20120024798Selenium Removal Using Chemical Oxidation and Biological Reduction - Selenium in the form of a reduced species such as selenocyanate is oxidized to produce an oxidized selenium species such as selenate or selenite, and then a biological reduction process is used to remove selenium from the oxidized selenium species. In an example, a chemical oxidant is added to a wastewater containing selenocyanate to produce selenate and selenite. The partially treated wastewater is then fed to a reactor containing a fixed media supporting a biofilm with selenium reducing organisms. The selenium in the selenate and selenite is reduced to an insoluble form of selenium, such as elemental selenium, which precipitates from the wastewater.02-02-2012

Yihong Ma, Lutz, FL US

Patent application numberDescriptionPublished
20110053977SMALL MOLECULE E2F INHIBITOR - A small molecular inhibitor of E2F (HLM006474) was identified using a computer-based virtual screen and the known crystal structure of the DNA bound E2F4/DP2 heterodimer. Treatment of multiple cell lines resulted in the loss of intracellular E2F4 DNA-binding activity. Overnight exposure to HLM006474 resulted in down regulation of total E2F4 protein as well as several known E2F targets. The effects of treatment on different cell lines included a reduction in cell proliferation and an increase in apoptosis. Apoptosis was induced in a manner distinct from cisplatin and doxorubicin. E2F4-null MEFs were less sensitive than wildtype counterparts to the apoptosis-inducing activity of the compound revealing its biological specificity. A375 cells were extremely sensitive to the apoptosis-inducing activity of the compound in two-dimensional culture and HLM006474 was a potent inhibitor of melanocytes proliferation and subsequent invasion in a three-dimensional tissue culture model system.03-03-2011

Yinfa Ma, Rolla, MO US

Patent application numberDescriptionPublished
20110147217METHOD AND APPARATUS FOR CANCER SCREENING - A method and apparatus for detection of pteridine levels in a biological sample using CE-LIF which is useful for early cancer screening involving fully oxidizing pteridine compounds in a sample such as a urine sample, subjecting to CE-LIF to assess compound concentration, and compare to expected levels in for healthy or cancer-bearing patients.06-23-2011

Yinqing Ma, Bethesda, MD US

Patent application numberDescriptionPublished
20110104344Heat-Stable Concentrated Milk Product - The invention provides a stable concentrated dairy liquid, such as concentrated milk, with improved flavor, color, and mouthfeel, and a method of production thereof. The method utilizes specific thermal treatments to produce the stable concentrated dairy liquid to which a stabilizer and mouthfeel enhancer are added. The resulting products have a sterilization value F05-05-2011
20110250327Intermediate Moisture Bar Using A Dairy-Based Binder - A chewy and intermediate moisture bar is provided that uses a dairy-based binder generally without the need to employ gums, humectants, and sugar syrups as a binder to achieve the moist and chewy texture. In one aspect, the bar includes a dry base uniformly blended with a dairy-based binder that uses high levels of dairy proteins as the main binding component. A method of forming the chewy and intermediate moisture bar is also provided that may use a lay or delay period to allow moisture equilibration or migration from the binder to the dry base.10-13-2011

Yupo Ma, Las Vegas, NV US

Patent application numberDescriptionPublished
20080241110Targeting of sall4 for the treatment and diagnosis of proliferative disorders associated with myelodysplastic syndrome (MDS) - The present invention discloses nucleic acids, proteins, and antibodies for SALL4 (including isoforms SALL4A, SALL4B, and SALL4C), a zinc finger transcriptional factor. Further, methods are disclosed which demonstrate that constitutive expression of SALL4 increases leukemogenic potential in cells of model animal systems. Moreover, constitutive expression of select isoforms (e.g., SALL4B) in transgenic mice demonstrate that these animals develop myelodysplastic syndrome (MDS)-like signs and symptoms, including subsequent acute myeloid leukemia (AML), which is transplantable. The disclosure also provides methods for identifying and purifying embryonic stem cells, adult stem cells, cancer stem cells, including leukemia stem cells, methods for identifying substances which bind to and/or modulate SALL4, methods for diagnosing MDS in a subject, and methods of treating a subject presenting MDS, AML and other forms of leukemia.10-02-2008
20080299077ISOLATION AND GROWTH OF STEM CELLS FROM HEMANGIOMAS - The present invention describes stem cells and progenitor cells derived from hemangiomas, including testing of angiogenic inhibitors using these cells. The invention as described is useful in providing a process to culture and propagate hemangioma stem cells and generate xenograft models to develop treatments for infantile hemangiomas and other types of vascular lesions.12-04-2008
20090191171Reprogramming of Differentiated Progenitor or Somatic Cells Using Homologous Recombination - The present invention provides methods and compositions for reprogramming somatic cells to a more primitive state, such as induced pluripotent stem cells, using homologous recombination. The induced pluripotent stem cells generated by the methods of the present invention are useful in a variety of therapeutic applications in the treatment and prevention of diseases and disorders.07-30-2009
20120030780TARGETING OF SALL4 FOR THE TREATMENT AND DIAGNOSIS OF PROLIFERATIVE DISORDERS ASSOCIATED WITH MYELODYSPLASTIC SYNDROME (MDS) - The present invention discloses nucleic acids, proteins, and antibodies for SALL4 (including isoforms SALL4A, SALL4B, and SALL4C), a zinc finger transcriptional factor. Further, methods are disclosed which demonstrate that constitutive expression of SALL4 increases leukemogenic potential in cells of model animal systems. Moreover, constitutive expression of select isoforms (e.g., SALL4B) in transgenic mice demonstrate that these animals develop myelodysplastic syndrome (MDS)-like signs and symptoms, including subsequent acute myeloid leukemia (AML), which is transplantable. The disclosure also provides methods for identifying and purifying embryonic stem cells, adult stem cells, cancer stem cells, including leukemia stem cells, methods for identifying substances which bind to and/or modulate SALL4, methods for diagnosing MDS in a subject, and methods of treating a subject presenting MDS.02-02-2012

Patent applications by Yupo Ma, Las Vegas, NV US

Zeyu Ma, Orlando, FL US

Patent application numberDescriptionPublished
20100282680SUPERHYDROPHOBIC MEMBRANE DISTILLATION FOR WATER PURIFICATION - A distillation membrane for purifying water includes a superhydrophobic surface having a plurality of protruding features that each include a microchannel therein that protrude from a recessed surface portion that is in a uniform thickness portion of the distillation membrane. A thickness of the uniform thickness portion defines a channel length of the distillation membrane. The distillation membrane includes a plurality of micropores that are each fluidicly coupled to respective ones of the microchannels, wherein the plurality of micropores extend through the channel length. The superhydrophobic surface is operable to reject liquid water and the microchannels coupled to the micropores are operable to pass water vapor therethrough to allow condensation of the water vapor on a side of the distillation membrane opposite the superhydrophobic surface.11-11-2010

Zhenbo Ma, Providence, RI US

Patent application numberDescriptionPublished
20090209046Neutral Pharmaceuticals - The invention comprises neutral multi-functionality assemblies of pharmaceuticals comprising an active medicinal functionality, a transition metal functionality, and an ancillary ligand functionality. An exemplary series of mixed-ligand coordination complexes comprised of copper(II), a drug and an ancillary ligand were made and tested. It is demonstrated that the judicious choice of an ancillary ligand affords a large degree of control over die relative lipophilicity/hydrophilicity of the complex in relation to the uncomplexed drug molecule. The important factors to be considered in the design of such complexes, such as the additive-constitutive nature of the partition coefficient of the ancillary ligand and the relative size of the two types of ligands are disclosed, and methods of designing neutral multi-functionality assemblies of pharmaceuticals are disclosed.08-20-2009

Zhiyong Ma, Hillsboro, OR US

Patent application numberDescriptionPublished
20110156801TAMPER RESISTANT FUSE DESIGN - A tamper resistant fuse design is generally presented. In this regard, an apparatus is introduced comprising a plurality of fuses in an integrated circuit device to store values and a plurality of resistors in parallel to the fuses, wherein each fuse includes a parallel resistor to provide a potential dissipation path around the fuse. Other embodiments are also described and claimed.06-30-2011