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Ma, MA
Dengke K. Ma, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110136145 | METHODS FOR PROMOTING FUSION AND REPROGRAMMING OF SOMATIC CELLS - The invention features methods for reprogramming somatic cells by treating the cells with one or more agents to induce de-differentiation, in particular by targeting demethylase and methyltransferase genes. The invention also features methods of monitoring somatic cell fusion and reprogramming and methods of identifying agents that alter somatic cell fusion and reprogramming. The invention also features reprogrammed cells and kits. | 06-09-2011 |
| 20120088812 | COMPOSITIONS FOR PROMOTING EPIGENETIC DNA DEMETHYLATION AND METHODS OF USE THEREFORE - The invention features compositions and methods for modulating the expression of Gadd45 and the use of such compositions and methods as neuroprotectants, to enhance neurogenesis, and for the treatment of mood disorders. | 04-12-2012 |
Eugene Y. Ma, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090026370 | PIXEL ARCHITECTURE FOR THERMAL IMAGING SYSTEM - A thermal imaging device including: a substrate; and an array of thermally tunable pixel elements for generating a thermal image, each thermally tunable pixel element including: a plurality of thermally tunable filter islands, each of which has a thermally tunable optical filter, wherein each of the plurality of tunable filter islands within that pixel element is thermally isolated from the other tunable filter islands within that tunable pixel element; an absorption structure for absorbing incident optical thermal energy; and a mechanical structure supporting the plurality of tunable filter islands and the absorption structure on the substrate. | 01-29-2009 |
| 20090195859 | METHOD OF SPATIALLY SEPARATING WAVELENGTHS OF MULTI-WAVELENGTH SIGNAL USING ELECTRONICALLY CONTROLLED THERMAL STRUCTURE - A thin-film interference filter structure has a generally wavelength-dependent resonant response to incident optical energy in a predetermined range of wavelengths. The thin-film interference filter structure includes a thermally tunable layer having a thermally tunable optical characteristic such that a range of wavelength-dependent resonant optical responses of the thermally tunable layer are induced by a corresponding range of thermal conditions of the thermally tunable layer. The thin-film interference filter structure is configured to (1) receive a spatially varying pattern of thermal energy at the thermally tunable layer to impart a corresponding spatially varying pattern to the thermally tunable characteristic of the thermally tunable layer, and (2) receive the incident optical energy into the thermally tunable layer and output optical energy having spatial modulation corresponding to the spatially varying pattern of the thermally tunable characteristic. | 08-06-2009 |
Eugene Yi-Shan Ma, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120294321 | THERMO-OPTICALLY TUNABLE LASER SYSTEM - A tunable laser has a solid state laser medium having an optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. Components of an external cavity include a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and the laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces with a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter ( | 11-22-2012 |
Fei Ma, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100188061 | METHOD AND APPARATUS FOR SWITCHING A SYNCHRONOUS DC/DC CONVERTER BETWEEN A PWM MODE OF OPERATION AND A LIGHT-LOAD MODE OF OPERATION - A synchronous buck converter operates in a PWM mode of operation and switches to light-load mode of operation under a light-load condition. When operating in the light-load mode, the synchronous buck converter transitions between a burst mode and an idle mode of operation. In the burst mode of operation, the converter operates with a fixed but increased duty ratio, with respect to the PWM mode of operation, that installs additional energy in an output capacitor. In the idle mode of operation, the high-side and low-side transistors are each turned off. To maximize energy savings and to quickly transition back to the PWM mode of operation if the load increases, a limit as to the number of allowed switching cycles when bursting is imposed and a minimum ratio of the number of clock cycles when idling to the number of switching cycles when bursting is set. Additionally, a comparator is provided to detect a sudden step-increase in the load to quickly switch the converter back to the PWM mode of operation. | 07-29-2010 |
| 20100253296 | SYMMETRIC SAMPLE AND HOLD OVER-CURRENT SENSING METHOD AND APPARATUS - An over-current condition is detected in a synchronous DC-DC converter by sampling and holding a measured load current value. The load current is sampled while a low-side transistor is ON and then held when the low-side transistor is OFF. The held value is compared to a threshold value while the low-side transistor is OFF. The comparison occurs during the portion of the cycle when the low-side transistor is OFF so that a comparator has sufficient time in which to detect the over-current condition, even in high duty cycle applications. | 10-07-2010 |
Fupeng Ma, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100168082 | Heterobicyclic Carboxamides as inhibitors for kinases - The invention relates to novel organic compounds of formula (I) | 07-01-2010 |
| 20120245187 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 09-27-2012 |
| 20130012529 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES - The invention relates to novel organic compounds of formula (I) | 01-10-2013 |
Hak-Ling Ma, Weymouth, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110159011 | USES OF IL-22, IL-17, AND IL-1 FAMILY CYTOKINES IN AUTOIMMUNE DISEASES - Methods of detecting inflammatory disorders using IL- 1 isoforms are provided. Methods of treating an inflammatory disorder with an anti-IL-1 antibody are also provided. Methods of treating an inflammatory disorder with an anti-IL-1 antibody and at least one of an anti-IL-22 antibody, an anti-IL-17 antibody, or an anti-TNFα antibody are also provided. | 06-30-2011 |
Hongshen Ma, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100041975 | PATIENT MONITORING SYSTEMS AND METHODS - Various systems and methods are provided for monitoring patient physiological data without the need for adhesives or wires to be connected to a patient. The system is also fully functional without the need for manipulation or intervention by a care provider or medical personnel. In particular, the system can include a pad having a plurality of electrical contacts or electrodes formed thereon in a predetermined pattern. The electrodes can be configured to sense electrical signals produced by a patient's body. A controller in communication with the electrodes can be configured to select and process signals from the electrodes and send the information derived from the electrical signals to an output device for displaying resulting physiological data so that the patient can be monitored. | 02-18-2010 |
| 20110031961 | ENDOTRACHEAL TUBE SENSOR - Various devices and methods for locating an object using magnetic fields are provided. In one embodiment, a device is provided having a housing with an array of sensors that can measure a magnetic field of an object and calculate a three dimensional location of the object based upon the measured magnetic field. A display device for displaying the three dimensional location of the object can also be included. In one exemplary embodiment, an implantable device, such as an endotracheal tube, is provided having the object embedded therein. The array of sensors can be used to measure the magnetic field of the object. The device can then calculate the three dimensional location of the object and the display device can display the calculated location of the object embedded in the implantable device. | 02-10-2011 |
Jing Ma, Belmont, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120202888 | BIOMARKERS OF PROSTATE CANCER AND PREDICTING MORTALITY - Measurement of circulating C-peptide levels is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of fatal prostate cancer. | 08-09-2012 |
Junqing Ma, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110117436 | Silicon Whisker and Carbon Nanofiber Composite Anode - A carbon nanofiber can have a surface and include at least one crystalline whisker extending from the surface of the carbon nanofiber. A battery anode composition can be formed from a plurality of carbon nanofibers each including a plurality of crystalline whiskers. | 05-19-2011 |
Laura Jane Poplawski Ma, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120176903 | NON-UNIFORM PER-PACKET PRIORITY MARKER FOR USE WITH ADAPTIVE PROTOCOLS - A method, apparatus and computer program product for non-uniform per-packet priority marking for use with adaptive protocols is presented. A packet is received at a first network device, the packet assigned to a priority band. A priority is determined for the packet between a lowest priority of the priority band and a highest priority of the priority band, the priority for the packet selected based on a target distribution of priorities within the priority band, the target distribution comprising a distribution selected to achieve a desired capacity relationship among groups of packets assigned to different priority bands. The selected priority is assigned to the packet. | 07-12-2012 |
Limin Ma, Lowell, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130064434 | BIOMETRIC FEATURE EXTRACTION USING MULTIPLE IMAGE INSTANTIATIONS - Systems and methods acquire and/or generate multiple different images of the same biometric identity, identify specific instances of biometric features in each of the different images, and merge the identified specific instances of biometric features into a data record that provides a digital representation of the biometric identity. Examples of biometric identities include fingerprints, handprints, palm prints, and thumbprints. In one embodiment, a counter is associated with each specific instance of a biometric feature found in the multiple images. Specific instances of biometric features found most frequently have high counts and are indicative of true identifications; those with low counts are indicative of false identifications. A threshold distinguishes between true and false identifications. Those specific instances with counts below the threshold are excluded when the digital representation of the biometric identity is generated. Thus, the methodology eliminates false identifications of specific instances of biometric features while accentuating true identifications. | 03-14-2013 |
Liting Ma, Needham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120015942 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF - This invention provides compounds of formula (I): | 01-19-2012 |
| 20120094997 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF - This invention provides compounds of formula (I): | 04-19-2012 |
Minglin Ma, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100178505 | FIBERS AND FIBER-BASED SUPERSTRUCTURES, THEIR PREPARATION AND USES THEREOF - This invention is directed to fibers comprising copolymers or homopolymer blends, superstructures comprising said fibers, process for the preparation of the same and uses thereof. The fibers of this invention have long range order and superstructures produced from said fibers can be used in applications including but not limited to membranes, filtration media, high surface area substrates for sensors and catalysis, stents, tissue scaffolds and drug delivery. | 07-15-2010 |
| 20110240550 | BLOCK COPOLYMER MEMBRANES AND ASSOCIATED METHODS FOR MAKING THE SAME - A separation matrix comprises a porous surface layer; and a bulk porous support, wherein both the porous surface layer and the bulk porous support comprising a block copolymer. The block copolymer comprises A-B or A-B-A repeating units, wherein A and B at each occurrence are two different blocks of oligomer, or polymer. A structural unit of block A is derived from one or more atom transfer radical polymerization (ATRP)-active monomer or oligomer and a structural unit of block B is derived from a thermoplastic ATRP-active macro initiator. A poly dispersity index of the block copolymer is at least about 2. | 10-06-2011 |
| 20120308650 | MODIFIED ALGINATES FOR CELL ENCAPSULATION AND CELL THERAPY - Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers. | 12-06-2012 |
Qiufu Ma, Needham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090170079 | Regulation of RUNX1 for Treatment of Pain - Methods are provides for identifying candidate agents for use in inhibiting expression of certain receptors and ion channels in nociceptors. Also provided are methods for identifying candidates agents for use in inhibiting neurophathic and other types of pain. | 07-02-2009 |
Richard Ma, Carlisle, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120010517 | STERILITY COVER FOR MEDICAL DEVICE SURFACE - An enclosure for a medical instrument including a pair of flexible sheets transmissive to a signal generated by a subject, the pair of sheets being arranged in parallel to each other, sealed along the sides and the top, and between the opposing lateral sides and the top and bottom ends along one or more seam lines. | 01-12-2012 |
Tracy Xiaoming Ma, Westford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090010263 | MoCA frame bundling and frame bursting - A system and method are provided for aggregating Multimedia over Coax Alliance (MoCA) Medium Access Control (MAC) frames. The method sends a Multiframe Reservation Request (MRR) requesting a transmission time slot, and receives a grant in response to the MRR. Subsequent to sending the MRR, a plurality of MoCA MAC frames are accepted and assembled into a physical layer (PHY) burst packet that is transmitted in the granted time slot. A method is also provided for bundling client data packets into a MoCA MAC frame. The method sends a Bundledpacket Reservation Request (BRR) requesting a transmission time slot, and receives a grant in response to the BRR. Subsequent to sending the BRR, a plurality of client data packets are accepted and concatenated into a bundled MoCA MAC frame. The bundled MoCA MAC frame is transmitted in a PHY packet in the granted time slot. | 01-08-2009 |
| 20100074624 | System and Method for Transporting Asynchronous ODUk Signals over a Synchronous Interface - System and methods are provided, in an Optical Transport Network (OTN), for communicating asynchronous Tributary Slots (TSs) via a synchronous Optical Payload Transport Unit of level k (OTUk) interface. The transmission method accepts a plurality of TSs at a corresponding plurality of asynchronous data rates. The TSs are mapped, using a tangible memory medium, into pseudo-Optical channel Data Tributary Unit (ODTU) frames synchronized to a common clock. Then, the synchronized pseudo-ODTU frames can be interleaved into an OTUk frame, without the need of a phase-locked loop (PLL) or buffering. | 03-25-2010 |
| 20100281343 | Virtual Lane Forward Error Correction in Multilane Distribution - A system and method are provided for generating virtual lane (VL) forward error correction (FEC) overhead (OH) in a communication multi-lane distribution (MLD) protocol transmitter, and for recovering data words from virtual lanes with FEC OH in an MLD protocol receiver. The transmission method accepts an Optical Transport Network (OTN) frame with n consecutively ordered payload chunks of data words, at a first data rate. Each payload chunk is assigned to a virtual lane data word (VLDW) in an MLD frame of n consecutively ordered VLDWs. The assignment order of payload chunks to VLDWs is rotated at the start of each MLD frame. VLDWs are joined into VLDW groups, where each VLDW group includes at least one VLDW. FEC blocks are calculated for VLDWs, creating ordered VL codewords (VLCWs). Then, the VLCWs are multiplexed to maintain a consistent assignment of VLCW order to physical transmission lanes and transmitted. | 11-04-2010 |
Vincent Ma, Shrewsbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110211518 | ADAPTIVE WIRELESS NETWORK - Systems, methods, and devices are provided for an adaptive wireless network. A wireless network device for an adaptive wireless network can include an application specific integrated circuit (ASIC) including logic and memory resources coupled to the ASIC. The logic can store information received from a number of clients associated with the wireless network device regarding capabilities of the number of clients in the memory resources. The logic can adapt a guard interval and/or a channel width for transmission of a data stream according to capabilities of a number of clients associated with the wireless network device. | 09-01-2011 |
| 20110216660 | SYNCHRONIZATION IN A WIRELESS NODE - A wireless node receives a beacon from a wireless access point. The beacon includes a wireless protocol time synchronization function (TSF) timestamp generated with reference to a global clock for a network. The wireless node synchronizes a counter according to the TSF timestamp. The wireless node receives a global timing offset (GTO) packet from the wireless access point and combines the GTO packet with a counter value to generate a global timestamp. | 09-08-2011 |
| 20120127970 | Wireless Network System And Method Configured To Mitigate Co-channel Interference - One embodiment provides a wireless network system ( | 05-24-2012 |
| 20120243520 | LOCATION-BASED ASSOCIATION FOR COMMUNICATIONS NETWORKS - In one implementation, a region descriptor associated with a communications access point and a location descriptor are accessed at a client. The client determines that a location described by the location descriptor is included within a region described by the region descriptor. The client then requests association with the communications access point in response to the determining. | 09-27-2012 |
Xiangdong Ma, North Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090017496 | Co-expression of multiple protein chains or subunits - A recombinant genetic construct is provided that includes at least two expression cassettes. Each cassette encodes for a chain or subunit of a target protein. The genetic construct preferably targets any expressed protein to the secretory pathway of the host cell. An application of present invention is found in expressing the two chains of human insulin through two separate expression cassettes on the same methylotrophic yeast expression vector. Mature, bioactive human insulin molecules are secreted through this method without resorting to any post-translational cleavage process. | 01-15-2009 |
Xiaoxu Ma, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090016614 | GLOBAL LOCALIZATION BY FAST IMAGE MATCHING - An efficient technique is provided for determining a portion of a document corresponding to a captured image. Areas of a document in which the pattern is at least partially obscured are identified. A reference pixel in the image is selected, and an offset between the pixel and the pattern is determined. A pixel-by-pixel comparison is then made of the image with the document such that the reference pixel is only compared with locations in the document that are both within the identified areas and have the determined offset from the pattern. The comparison with the highest correspondence between the image pixels and the electronic document then identifies the position of the reference pixel relative to the electronic document. | 01-15-2009 |
Xinfa Ma, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120148245 | MULTIPLEX CONVERSION FOR A PASSIVE OPTICAL NETWORK - A passive optical network system having a node that is optically coupled to optical line terminals (OLTs), and that is optically coupled to optical network units (ONUs). The node includes at least one fiber link module (FLM), each FLM including an upstream multiplex conversion device (MCD), and a downstream MCD. The upstream MCD receives an upstream optical signal from the ONUs, converts the upstream optical signal to an upstream electrical signal, and transmits a regenerated upstream optical signal to the OLTs. The downstream MCD receives a downstream optical signal from the OLTs, converts the downstream optical signal to a downstream electrical signal, and transmits a regenerated downstream optical signal to the ONUs. | 06-14-2012 |
Yao Ma, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100267150 | HDM2 POLYPEPTIDES - The present invention relates to HDM2 polypeptides and mutants thereof which are complexed with various compounds, e.g., HDM2 inhibitors. | 10-21-2010 |
| 20120208844 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF - The present invention provides a compound of Formula (1) as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same. | 08-16-2012 |
Yi Ma, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080202575 | METHODS FOR HIGH FIGURE-OF-MERIT IN NANOSTRUCTURED THERMOELECTRIC MATERIALS - Thermoelectric materials with high figures of merit, ZT values, are disclosed. In many instances, such materials include nano-sized domains (e.g., nanocrystalline), which are hypothesized to help increase the ZT value of the material (e.g., by increasing phonon scattering due to interfaces at grain boundaries or grain/inclusion boundaries). The ZT value of such materials can be greater than about 1, 1.2, 1.4, 1.5, 1.8, 2 and even higher. Such materials can be manufactured from a thermoelectric starting material by generating nanoparticles therefrom, or mechanically alloyed nanoparticles from elements which can be subsequently consolidated (e.g., via direct current induced hot press) into a new bulk material. Non-limiting examples of starting materials include bismuth, lead, and/or silicon-based materials, which can be alloyed, elemental, and/or doped. Various compositions and methods relating to aspects of nanostructured thermoelectric materials (e.g., modulation doping) are further disclosed. | 08-28-2008 |
Yi Hua Ma, Worcester, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100132546 | Composite Structures with Porous Anodic Oxide Layers and Methods of Fabrication - Composite structures are described that have a porous anodic oxide layer such as, for example, a porous anodic aluminum oxide layer. In one aspect, the present invention includes a composite gas separation module having a porous metal substrate; a porous anodic aluminum oxide layer, wherein the porous anodic aluminum oxide layer overlies the porous metal substrate; and a dense gas-selective membrane, wherein the dense gas-selective membrane overlies the porous anodic aluminum oxide layer. A composite filter is described having a porous non-aluminum metal substrate; and a porous anodic aluminum oxide layer, wherein the porous anodic aluminum oxide layer defines pores extending through the porous anodic aluminum oxide layer. Methods for fabricating composite gas separation modules and composite filters and methods for selectively separating hydrogen gas from a hydrogen gas-containing gaseous stream are also described. | 06-03-2010 |
| 20110303092 | High Permeance Sulfur Tolerant Pd/Cu Alloy Membranes - A method of making a membrane permeable to hydrogen gas (H | 12-15-2011 |
Yinong Ma, Longmeadow, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090118437 | Interlayers Comprising Glycerol Based Plasticizer - The present invention includes interlayers and multiple layer glazing panels comprising those interlayers, wherein the interlayers comprise poly(vinyl butyral) and a glycerol based plasticizer. The addition of the glycerol based plasticizer surprisingly results in a plasticized poly(vinyl butyral) layer that is suitable for use in a wide range of multiple layer glazing applications. | 05-07-2009 |
Yufeng Ma, Needham Heights, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110024302 | Molecular Imprinted Nanosensors And Process For Producing Same - A molecular recognition sensor system is provided incorporating a molecular imprinted nanosensor device formed by the process steps of: | 02-03-2011 |
Yufeng Ma, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100323918 | POLYMER SURFACE FUNCTIONALIZATION AND RELATED APPLICATIONS - A method to assemble functional materials, such as nanomaterials, onto a polymer surface to create a corresponding functionalized surface involves creating a solution of the functional material, providing a sacrificial substrate, disposing the functional solution onto a surface of the substrate and then covering the substrate with a liquid polymer. The sacrificial substrate is then dissolved, leaving behind a functional surface embedded within the cured polymer. One specific aspect of the invention relates to the embedding of functionalized carbon nanotubes onto a polymer surface for creating a nano-engineered surface. Devices employing functional surfaces are disclosed that are suitable for the immobilization of enzymes, DNA, peptides, proteins, cells, catalyst, and/or other chemicals or molecules for chemical, biochemical, or biological analysis, reactions, filtration. | 12-23-2010 |
Yu-Tung Ma, Needham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110306560 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES - Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses. | 12-15-2011 |
Zuwei Ma, Woburn, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120156176 | THERMORESPONSIVE, BIODEGRADABLE, ELASTOMERIC MATERIAL AND USES THEREFOR - Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. | 06-21-2012 |