Patent application number | Description | Published |
20090197732 | LOCKING DIFFERENTIAL HAVING A SPLIT-CENTER DRIVER - A locking differential includes a housing with an interior chamber in which a two-piece split-center driver is located. The split-center driver is positioned on opposite sides of a cross-pin assembly. A pair of axially spaced output shafts extend from the interior chamber and are coupled to a pair of side gears. The split-center driver gear and a centered cam member are arranged co-axially about the adjacent ends of the output shafts, and annular clutch members are operable to disconnect an overrunning output shaft | 08-06-2009 |
20100093481 | LOCKING DIFFERENTIAL HAVING IMPROVED CLUTCH TEETH - A hold-out ring type locking differential for an automobile or other type of motorized vehicle includes a differential case housing a number of components, such as a center driver positioned between holdout rings, clutch members, springs, spring retainers, side gears, and thrust washers. The center driver includes a center cam that engages inner teeth of the clutch members, which in turn include a tooth shape or profile for reducing stress and wear while increasing an operational life of the clutch member. The inner clutch teeth each have a top portion coupled to a base portion at an intersection point. The top portion extends from the intersection point to a free edge surface while the base portion extending from the intersection point continually into a root radius region. | 04-15-2010 |
20110015026 | LOCKING DIFFERENTIAL HAVING A SPLIT-CENTER DRIVER - A locking differential includes a housing with an interior chamber in which a two-piece split-center driver is located. The split-center driver is positioned on opposite sides of a cross-pin assembly. A pair of axially spaced output shafts extend from the interior chamber and are coupled to a pair of side gears. The split-center driver gear and a centered cam member are arranged co-axially about the adjacent ends of the output shafts, and annular clutch members are operable to disconnect an overrunning output shaft | 01-20-2011 |
20120318629 | LOCKING DIFFERENTIAL HAVING IMPROVED CLUTCH TEETH - A hold-out ring type locking differential for an automobile or other type of motorized vehicle includes a differential case housing a number of components, such as a center driver positioned between holdout rings, clutch members, springs, spring retainers, side gears, and thrust washers. The center driver includes a center cam that engages inner teeth of the clutch members, which in turn include a tooth shape or profile for reducing stress and wear while increasing an operational life of the clutch member. The inner clutch teeth each have a top portion coupled to a base portion at an intersection point. The top portion extends from the intersection point to a free edge surface while the base portion extending from the intersection point continually into a root radius region. | 12-20-2012 |
Patent application number | Description | Published |
20090017034 | Antibodies that inhibit TSLP activity - The invention is directed to purified and isolated novel TSLP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. | 01-15-2009 |
20090075886 | Dendritic cell stimulatory factor - Flt3-ligand can be used to generate large numbers of dendritic cells from hematopoietic progenitor and stem cells. Flt3-ligand can be used to augment immune responses in vivo, and expand dendritic cells ex vivo. Such dendritic cells can then be used to present tumor, viral or other antigens to naive T cells, can be useful as vaccine adjuvants. | 03-19-2009 |
20100167393 | MODIFIED HUMAN THYMIC STROMAL LYMPHOPOIETIN - Modified, furin resistant human TSLP polypeptides and polynucleotides encoding the modified human TSLP polypeptides are provided. Pharmaceutical compositions, B and T cell activation agents, assays and methods of use are also described. | 07-01-2010 |
20100266601 | ANTIBODIES THAT INHIBIT TSLP ACTIVITY - The invention is directed to purified and isolated novel TSLP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. | 10-21-2010 |
20110053863 | METHODS OF USING FLT3-LIGAND IN THE TREATMENT OF CANCER - Ligands for flt3 receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells are disclosed. The invention is directed to Flt3-ligand as an isolated protein, the DNA encoding the Flt3-ligand, host cells transfected with cDNAs encoding Flt3-ligand, compositions comprising Flt3-ligand and methods of using Flt3-ligand in hematopoietic cell transplantation. | 03-03-2011 |
20110230637 | MODIFIED HUMAN THYMIC STROMAL LYMPHOPOIETIN - Modified, furin resistant human TSLP polypeptides and polynucleotides encoding the modified human TSLP polypeptides are provided. Pharmaceutical compositions, B and T cell activation agents, assays and methods of use are also described. | 09-22-2011 |
20120014961 | ANTIBODIES THAT INHIBIT TSLP ACTIVITY - The invention is directed to purified and isolated novel TSLP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. | 01-19-2012 |
20130225490 | Antibodies That Inhibit TSLP Activity - The invention is directed to purified and isolated novel TSLP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above. | 08-29-2013 |
20140093956 | Modified Human Thymic Stromal Lymphopoietin - Modified, furin resistant human TSLP polypeptides and polynucleotides encoding the modified human TSLP polypeptides are provided. Pharmaceutical compositions, B and T cell activation agents, assays and methods of use are also described. | 04-03-2014 |