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Lusine
Lusine Danielyan, Tubingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20100278786 | USE OF THE OPPOSITE CELL DIFFERENTIATION PROGRAM (OCDP) FOR THE TREATMENT OF DEGENERATED ORGANS IN THE PATHOLOGICAL STATE - The present invention relates to a method for the treatment of organs which are degenerative and/or in the pathological state by means of the use of cells, which are phenotypically stably differentiating or differentiated but not necessarily ultimately predetermined with respect to development, from a donor organ selected according to the principles of the opposite cell differentiation program (OCDP) and also to the use of cells of this type for the treatment or for the production of a drug for treatment of the same. Furthermore, the present invention relates to pharmaceutical agents comprising suitable phenotypically stable cells, cells of a first organ which is different from the second organ with respect to organ type thereby being used, which, in the normal physiological state with respect to a predetermined set of expressed genes and/or phenotypical properties, have opposite properties to the second cells in the normal physiological state. | 11-04-2010 |
Lusine Danielyan, Tuebingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090068155 | METHODS, PHARMACEUTICAL COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ADMINISTERING THERAPEUTIC CELLS TO THE ANIMAL CENTRAL NERVOUS SYSTEM - Methods and compositions for preventing and treating the damaged and/or degenerating CNS experiencing loss or death of CNS cells. Various embodiments of the invention transport a therapeutically effective amount of, inter alia, at least one therapeutic cell to the CNS by intranasal application to the upper-third of the nasal cavity, thereby bypassing the blood-brain barrier. A pharmaceutical composition according to the invention may comprise at least one therapeutic cell, at least one delivery-enhancement agent, at least one antibiotic, at least one regulatory factor and/or at least one immunosuppressive agent, wherein the composition is delivered to the upper-third of the nasal cavity. The therapeutic cells, once delivered to the CNS, migrate preferentially to the area of damage or degeneration or injury. | 03-12-2009 |
Lusine Yepremyan, Glendale, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110218836 | Seasonality-Based Rules for Data Anomaly Detection - In one embodiment, we describe a method that generates seasonality rules for anomaly detection for a hierarchical/tree based data structure. A new algorithm for processing nodes in hierarchy, as well as business rules for nodes, is described. Variations and examples are given to describe different scopes and embodiments of the invention. Exclusion criteria and children nodes are used as some examples for the implementations, with flow charts to describe the methods of application, as examples. | 09-08-2011 |