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Luscher
Daniel Luscher, Holziken CH
| Patent application number | Description | Published |
|---|---|---|
| 20090170950 | Inhibitors Of Neurotrypsin - The invention relates to a method for determining whether a compound is a neurotrypsin inhibitor, characterized in that the compound is incubated together with neurotrypsin, a variant thereof or a fragment comprising the protease domain and with a protein or peptide comprising agrin, a variant thereof or a fragment comprising the α- or the β-cleavage site of agrin, in an aqueous buffer solution, and the amount of cleavage of agrin is measured. Additionally, the invention relates to inhibitors of neurotrypsin found by this method, in particular to compounds of formula | 07-02-2009 |
Hans Luscher, St. Jean-Baptist CA
| Patent application number | Description | Published |
|---|---|---|
| 20090245947 | UNIVERSAL ROTARY CUTTER HEAD WITH BACK CLAMPING SYSTEM AND CONSTANT CUTTING DIMENSIONS AND CONSTANT WEIGHT REGRIDABLE INSERTS - A rotary cutting tool has a cutting insert clamped from behind by a backing clamp against a frontal abutment defined in the body of the rotary cutter head. The clamp backs the cutting insert against the cutting pressure during operation and provides for the use of a same rotary cutter with different profiles of cutting inserts. Plugs of predetermined weight can be inserted in pre-formed holes in the cutting insert to permit recalibration of the insert after a sharpening operation. | 10-01-2009 |
Mark Luscher, Toronto CA
| Patent application number | Description | Published |
|---|---|---|
| 20090325217 | METHOD AND APPARATUS FOR SORTING CELLS - A method, apparatus, and system for a sorting flow cytometer include an objective lens having an optical axis coaxially aligned with the flow path at the focal point. A controllable energy source selectively alters an analyte according to a determination of whether the analyte is in a desired sub-population. In various embodiments, one or both of the emission from the controllable energy source and/or the emission from an illumination energy source passes through the objective lens. In some embodiments in which the emission from the controllable energy source passes through the objective lens, the objective lens may focus the emission from the controllable energy source at a different point than the focal point of a signal detected from the analyte and, in particular, at a point closer to the objective lens. | 12-31-2009 |
| 20100328664 | METHOD AND APPARATUS FOR LIMITING EFFECTS OF REFRACTION IN CYTOMETRY - A method and apparatus for performing cell cytometry mitigate or eliminate the effects of refraction that result from interfaces between materials having different refractive indices. Solid materials, such as the walls of a flow path, which materials are disposed between a nominal focal point and an objective lens, are formed of a material having a refractive index between 1.30 and 1.40 inclusive. The refractive index of a liquid material, such as an immersion fluid or a fluid carrying, suspending, or bathing an analyte, may be adjusted to have a refractive index closer to that of surrounding solid materials and, in particular, within 0.02 of the refractive index of the surrounding solid materials. | 12-30-2010 |
Patrik Luscher, Pfaffikon CH
| Patent application number | Description | Published |
|---|---|---|
| 20090053673 | METHOD FOR LOCALIZED TREATMENT OF PERIODONTAL TISSUE - A method for localized treatment using a microneedle array to controllably administer a dose of a bone anabolic drug localized at a dental implant site. The bone anabolic drug enhances alveolar bone growth at the dental implant site. Examples of drugs that may be used include, but are not limited to, bone anabolic drugs (e.g., bone morphogenetic proteins, fibroblast growth factor 2, statins parathyroid hormone), and/or drugs that target cell signalling pathways involved in the regulation of the osteoblastic lineage and function. In one embodiment, the method includes monitoring the dental implant site for periodontal tissue generation sufficient to support a dental implant. When sufficient tissue is generated, the dental implant is surgically inserted in the dental implant site. Additional doses of the bone anabolic drug may be delivered prior to detecting tissue generation. | 02-26-2009 |
| 20090192609 | IMPLANT DEVICE FOR USE IN AN IMPLANT SYSTEM - An implant device | 07-30-2009 |
Robert Luscher, Seon CH
| Patent application number | Description | Published |
|---|---|---|
| 20090188715 | INSULATOR DISK FOR SUPPORTING A LINEAR CONDUCTOR, AND AN ELECTRICAL ASSEMBLY INCLUDING SUCH A DISK - An electrical insulator disk has central recesses and peripheral recesses to enable the disk to be mounted floatingly relative to flanges between which the disk is held and to a linear conductor that extends through the disk. | 07-30-2009 |
Walter G. Luscher, Kennewick, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090118145 | METHOD FOR PRODUCING PROPPANT USING A DOPANT - A method for producing sintered pellets and sintered pellets produced therefrom including mixing a dopant with water and kaolin clay to form substantially round and spherical green pellets and sintering the pellets to form a proppant. The dopant is selected from the group consisting of potassium carbonate, potassium sulfate, potassium chloride, mica, kalsilite, and combinations thereof. | 05-07-2009 |