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Lupi
Andrea Lupi, Octeville Sur Mer FR
| Patent application number | Description | Published |
|---|---|---|
| 20080210334 | Filing Valve Having a Liquid Chamber, a Gas Chamber and a Medium Chamber, and Filling Machine Comprising the Same - Filling valve ( | 09-04-2008 |
| 20080283788 | Filling Valve Having a Three-Position Valve Rod - Filling valve ( | 11-20-2008 |
| 20090100799 | FILLING VALVE HAVING A LIQUID CHAMBER, A GAS CHAMBER AND A MEDIUM CHAMBER, AND FILLING MACHINE COMPRISING THE SAME - Filling valve ( | 04-23-2009 |
Giuseppe Lupi, Gallicano (lucca) IT
| Patent application number | Description | Published |
|---|---|---|
| 20120085856 | APPARATUS AND METHOD FOR EXCHANGE OF CORES IN A WINDING MACHINE - A method and an apparatus for exchange of cores in a machine for winding a continuous layer of paper ( | 04-12-2012 |
Rosita Lupi, Milan IT
| Patent application number | Description | Published |
|---|---|---|
| 20100035876 | Use of a Kinase Inhibitor for the Treatment of Particular Resistant Tumors - The invention provides low molecular weight compounds, namely tetrahydropyrrolo[3,4-c]pyrazoles, showing a high affinity for the ATP pocket of ABL tyrosine kinase. These compounds are thus ATP-competitive tyrosine kinase inhibitors displaying a significant inhibitory potency also, and in particular, towards BCR-ABL inhibitor-resistant T315I ABL mutants. The compounds of the invention find a useful application in the treatment of BCR-ABL inhibitor-resistant ABL-mediated diseases, such as Imatinib-resistant chronic myelogenous leukemia. Moreover, the invention provides a screening method for the identification of compounds capable of binding the ATP pocket of a kinase protein, in particular of the T315I mutant ABL kinase. | 02-11-2010 |
Rosita Lupi, Legnano IT
| Patent application number | Description | Published |
|---|---|---|
| 20100022532 | USE OF A KINASE INHIBITOR FOR THE TREATMENT OF PARTICULAR RESISTANT TUMORS - The invention provides low molecular weight compounds, namely 1H-thieno[2,3-c]pyrazoles, showing a high affinity for the ATP pocket of ABL tyrosine kinase. These compounds are thus ATP-competitive tyrosine kinase inhibitors displaying a significant inhibitory potency also, and in particular, towards BCR-ABL inhibitor-resistant T315I ABL mutants. The compounds of the invention find a useful application in the treatment of BCR-ABL inhibitor-resistant ABL-mediated diseases, such as Imatinib-resistant chronic myelogenous leukemia. Moreover, the invention provides a screening method for the identification of compounds capable of binding the ATP pocket of a kinase protein, in particular of the T315I mutant ABL kinase. | 01-28-2010 |
Vittoria Lupi, Milan IT
| Patent application number | Description | Published |
|---|---|---|
| 20100034837 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS - The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors. | 02-11-2010 |