Luksha
Nicholas Luksha, Malden, MA US
Patent application number | Description | Published |
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20110033464 | IMMUNOGLOBULIN FUSION PROTEIN FORMULATIONS - The present invention provides compositions of Ig fusion proteins, especially compositions including an Ig fusion protein, a bulking agent, a disaccharide, a surfactant, and a buffer. In one aspect, these compositions are stable under long-term storage or at least one freeze/thaw cycle. The invention also provides methods of preparation of the Ig fusion protein compositions. In one aspect, compositions of the invention are lyophilized. In a further aspect, the compositions are lyophilized by a process that includes an annealing step. | 02-10-2011 |
Nicholas Luksha, Andover, MA US
Patent application number | Description | Published |
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20120114646 | LYOPHILIZED FORMULATIONS FOR SMALL MODULAR IMMUNOPHARMACEUTICALS - The present invention provides, among other things, stable formulations for small modular immunopharmaceutical (SMIP™) proteins. In some embodiments, the present invention provides a formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, wherein less than 7% of the lyophilized small modular immunopharmaceutical protein exists in aggregated form. Formulations according to the invention may contain buffering agents, stabilizers, bulking agents, surfactants and/or other excipients. The present invention also provides formulations for lyophilization, reconstitution and methods of use thereof. | 05-10-2012 |
Nicholas Gary Luksha, North Andover, MA US
Patent application number | Description | Published |
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20130164310 | ANTI-DIABETIC COMPOUNDS - The present invention provides a composition of the formula: [FGF21-1 | 06-27-2013 |