Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Lukhtanov, WA
Eugene Lukhtanov, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20080293586 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND - Minor groove binder-oligonucleotide probes are provided along with methods for their use wherein the probes have an attached fluorophore which, in an unhybridized form exhibits very low background signal. | 11-27-2008 |
| 20090111100 | MINOR GROOVE BINDER - ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE - The incorporation of a minor groove binder spaced close to one member of a matched FRET set in a minor groove binder-oligonucleotide conjugate significantly reduces background fluorescence of a FRET probe or pair of probes and, consequently, increases the S/B ratios. Fluorescent-labeled probes are useful in carrying out hybridization, multiplex nucleic acid detection, and other procedures. | 04-30-2009 |
Eugene Lukhtanov, Bothel, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090093612 | AMIDE-SUBSTITUTED XANTHENE DYES - The present invention provides amide-substituted xanthene fluorescent dyes and reagent for the introduction of phosphonate or sulfo groups into the fluorescent dyes. | 04-09-2009 |
Eugeny Lukhtanov, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20080207887 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES - Reagents are provided for the introduction of phosphonate groups into fluorescent dyes. Methods are also provided for preparing dye conjugates. | 08-28-2008 |
| 20100261903 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES - Reagents are provided for the introduction of phosphonate groups into fluorescent dyes. Methods are also provided for preparing dye conjugates. | 10-14-2010 |
Eugeny A. Lukhtanov, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090048427 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS - Conjugates between a minor groove binding molecule, such as the trimer of 1,2-dihydro-(3H)-pyrrolo[3,2-e]indole-7-carboxylate (CDPI | 02-19-2009 |
| 20100137614 | NEGATIVELY CHARGED MINOR GROOVE BINDERS - The present invention provides a negatively charged minor groove binding compound, oligonucleotide conjugates comprising the same, and methods for using the same. The negatively charged minor groove binding compounds of the present invention comprises an acidic moiety that is capable of being ionized under physiological conditions. In particular, the negatively charged minor groove binding compound of the present invention comprises a binding moiety that binds preferentially into a minor groove of a double, triple or higher stranded DNA, RNA, PNA or hybrids thereof. The binding moiety comprises at least one aryl moiety and an acidic moiety which is covalently attached to a phenyl portion of the aryl moiety or to a heteroatom of a heteroaryl portion of the aryl moiety. | 06-03-2010 |
Eugeny Alexander Lukhtanov, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100174058 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS - Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group. | 07-08-2010 |