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Luke, US

April Luke, Chapel Hill, NC US

Patent application numberDescriptionPublished
20090233307METHODS FOR DETECTION OF SINGLE STRAND BREAKS IN DNA - Methods are provided for detecting single strand breaks in DNA sample comprising: contacting the DNA with a neutral hydroxylamine, denaturing the DNA and detecting single strand breaks in the denatured DNA. Methods are also provided for the detecting single strand breaks in DNA from a cell, the methods comprising lysing the cell, denaturing the DNA from the lysed cell, wherein the DNA is contacted with a neutral hydroxylamine prior to and/or during the denaturing step and detecting single strand breaks in the DNA from the cell. In addition, methods are provided for distinguishing between true single strand breaks and artifactual single strand breaks resulting from cleaved alkaline labile sites.09-17-2009

Catherine J. Luke, Rockville, MD US

Patent application numberDescriptionPublished
20120045467INFLUENZA VIRUS VACCINE COMPOSITION AND METHODS OF USE - The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV protein or a fragment, a variant, or a derivative thereof. The present invention is further directed to enhancing the immune response of a human in need of protection against IV infection by administering, in vivo, into a tissue of the human, at least one IV protein or a fragment, a variant, or derivative thereof. The IV protein can be, for example, in purified form or can be an inactivated IV, such as those present in inactivated IV vaccines. The polynucleotide is incorporated into the cells of the human in vivo, and an immunologically effective amount of an immunogenic epitope of an IV, or a fragment, variant, or derivative thereof is produced in vivo. The IV protein (in purified form or in the form of an inactivated IV vaccine) is also administered in an immunologically effective amount.02-23-2012

Catherine J. Luke, Frederick, MD US

Patent application numberDescriptionPublished
20100197771INFLUENZA VIRUS VACCINE COMPOSITION AND METHODS OF USE - The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV protein or a fragment, a variant, or a derivative thereof. The present invention is further directed to enhancing the immune response of a human in need of protection against IV infection by administering, in vivo, into a tissue of the human, at least one IV protein or a fragment, a variant, or derivative thereof. The IV protein can be, for example, in purified form or can be an inactivated IV, such as those present in inactivated IV vaccines. The polynucleotide is incorporated into the cells of the human in vivo, and an immunologically effective amount of an immunogenic epitope of an IV, or a fragment, variant, or derivative thereof is produced in vivo. The IV protein (in purified form or in the form of an inactivated IV vaccine) is also administered in an immunologically effective amount.08-05-2010

Patent applications by Catherine J. Luke, Frederick, MD US

Geoffrey P. Luke, Austin, TX US

Patent application numberDescriptionPublished
20120001058MULTI-APERTURE VISUAL SENSOR WITH HYPERACUITY - A multi-aperture passive light sensor and method for detecting motion and edges of an object are described. The sensor may include at least two focusing lenses mounted on a spherical surface for focusing light from the object into the ends of optical fibers, the optical axis for each lens diverging at an angle from that of adjacent lenses depending on the intended application. Each lens is located closer to the end of its associated optical fiber, which is disposed coaxially to the optical axis of the lens, than the natural focal plane of the lens, thereby blurring the light received from the object. Light exiting the fibers is detected by photosensors located at the opposite end of each optical fiber, and voltage differences between the voltages generated in response to the light intensity impinging on the photosensors are used to detect motion and edges of the object.01-05-2012

George P. Luke, Clinton, CT US

Patent application numberDescriptionPublished
20080227793Benzimidazole and Pyridylimidazole Derivatives - This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I09-18-2008
20100217012COMPOUNDS AND PROCESSES FOR PREPARING SUBSTITUTED AMINOMETHYL-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e]INDOL-8-ONES - Processes and intermediates are provided for the preparation of substituted aminomethyl 2,3,8,9-tetrahydiO-7H-1,4-dioxino[2.3-e]indo]-8-ones of the Formula (A) wherein the variables n, R and R08-26-2010
20100267698Benzimidazole and Pyridylimidazole Derivatives - This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I10-21-2010

Patent applications by George P. Luke, Clinton, CT US

Glenn P. Luke, Brookings, SD US

Patent application numberDescriptionPublished
20080225143Pixel interleaving configurations for use in high definition electronic sign displays - Pixel interleaving configurations for use in high definition electronic sign displays where each and every scan line includes full red, green, and blue color representation to provide for high resolution electronic video sign displays.09-18-2008
20110163942PIXEL INTERLEAVING CONFIGURATIONS FOR USE IN HIGH DEFINITION ELECTRONIC SIGN DISPLAYS - Pixel interleaving configurations for use in high definition electronic sign displays where each and every scan line includes full red, green, and blue color representation to provide for high resolution electronic video sign displays.07-07-2011
20110175888PIXEL INTERLEAVING CONFIGURATIONS FOR USE IN HIGH DEFINITION ELECTRONIC SIGN DISPLAYS - Pixel interleaving configurations for use in high definition electronic sign displays where each and every scan line includes full red, green, and blue color representation to provide for high resolution electronic video sign displays.07-21-2011

Hok-Sum H. Luke, Bellevue, WA US

Patent application numberDescriptionPublished
20090116181ELECTRONIC DEVICES WITH SURFACE FEATURES - Electronic devices with surface features are disclosed. The electronic devices includes a processor and a display operatively coupled to the processor for presenting outputs to a user. The electronic devices also includes a housing having a first portion and a second portion coupled to the first portion to form an enclosure containing the processor and the display. The second portion includes a plurality of edges proximate to the first portion, an end surface spaced apart from the edges, and a plurality of side surfaces extending between the edges and the end surface. At least one of the side surfaces is canted relative to the end surface.05-07-2009
20100159998METHOD AND APPARATUS FOR AUTOMATICALLY CHANGING OPERATING MODES IN A MOBILE DEVICE - A method and system for automatically changing the operating mode of a mobile device in response to changes in positioning or the use of the device includes multiple sensors that provide information relating to the mobile device and its environment. The sensors determine positioning information, incident light intensity, and object proximity and detect the presence of a pointer device. The system monitors the sensors and applications executed by the operating system. Based on the monitoring, the system changes the operating mode of the mobile device.06-24-2010

Hok-Sum Horace Luke, Mercer Island, WA US

Patent application numberDescriptionPublished
20100293056Tile Space User Interface For Mobile Devices - The subject disclosure pertains to systems and methods for providing an improved user interface for mobile devices. Data and services available through the mobile device can be represented as a set of tiles maintained in a display space. The tiles provide a snapshot of the current state of content available through the mobile device without requiring any interaction by the user. The tiles and display space are customizable and can be dynamically updated to display content to a user. In addition, tiles can provide functionality, including simple tasks to a user without requiring the user to navigate away from the tile display space. Tiles can also provide quick access to start software applications. Tiles can be organized in the display space by the user or the tiles can be automatically grouped based upon associated metadata.11-18-2010

Patent applications by Hok-Sum Horace Luke, Mercer Island, WA US

James Luke, Huntsville, AL US

Patent application numberDescriptionPublished
20120062872Mesh Sensor for Measuring Directed Energy - A mesh sensor system for measuring the performance of directed energy weapons at a target has been developed. The mesh sensor system measures the laser irradiance and the thermal response on the target. The system includes a plurality of sensors arranged on the target surface and a plurality connecting lines that connect with the sensors to provide power and retrieve data from the sensors.03-15-2012

May Luke, San Francisco, CA US

Patent application numberDescriptionPublished
20090221620GENTIC POLYMORPHISMS ASSOCIATED WITH STROKE, METHODS OF DETECTION AND USES THEREOF - The present invention provides compositions and methods based on genetic polymorphisms that are associated with vascular diseases such as stroke. In particular, the present invention relates to genetic polymorphisms that have utility for such uses as predicting disease risk or predicting an individual's response to a treatment such as statins, including groups of polymorphisms that may be used as a signature marker set for such uses, as well as nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.09-03-2009
20110269735GENETIC POLYMORPHISMS ASSOCIATED WITH STATIN RESPONSE AND CARDIOVASCULAR DISEASES, METHODS OF DETECTION AND USES THEREOF - The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment, particularly for reducing the risk of cardiovascular disease, especially coronary heart disease (such as myocardial infarction) and stroke. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents and kits for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents and kits for their detection.11-03-2011

Patent applications by May Luke, San Francisco, CA US

May M. Luke, San Francisco, CA US

Patent application numberDescriptionPublished
20090170111GENETIC POLYMORPHISMS ASSOCIATED WITH STROKE, METHODS OF DETECTION AND USES THEREOF - The present invention is based on the discovery of genetic polymorphisms that are associated with vascular diseases, particularly stroke. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.07-02-2009

Patent applications by May M. Luke, San Francisco, CA US

Mike A. Luke, Houston, TX US

Patent application numberDescriptionPublished
20090065257APPARATUS AND METHODS FOR UTILIZING A DOWNHOLE DEPLOYMENT VALVE - Methods and apparatus for utilizing a downhole deployment valve (DDV) to isolate a pressure in a portion of a bore are disclosed. The DDV system can include fail safe features such as selectively extendable attenuation members for decreasing a falling object's impact, a normally open back-up valve member for actuation upon failure of a primary valve member, or a locking member to lock a valve member closed and enable disposal of a shock attenuating material on the valve member. Actuation of the DDV system can be electrically operated and can be self contained to operate automatically downhole without requiring control lines to the surface. Additionally, the actuation of the DDV can be based on a pressure supplied to an annulus.03-12-2009
20100089591EXPANDABLE LINER HANGER AND METHOD OF USE - The present invention generally relates to an expandable liner hanger capable of being expanded into a surrounding casing. In one aspect, an expandable tubular system is provided. The system includes an expandable tubular. The system further includes an expansion swage for expanding the expandable tubular, wherein the expansion swage is deformable from a compliant configuration to a smaller substantially non-compliant configuration. Additionally, the system includes a restriction member disposed on an exterior surface of the expandable tubular, wherein expansion of the expandable tubular in the location of the restriction member deforms the expansion swage from the compliant configuration to the smaller substantially non-compliant configuration. In another aspect, a method of expanding a liner hanger using a cone is provided.04-15-2010
20100089592COMPLIANT EXPANSION SWAGE - The present invention generally relates to a swage assembly that is movable from a compliant configuration having a first shape to a substantially non-compliant configuration having a second shape. In one aspect, an expansion swage for expanding a wellbore tubular is provided. The expansion swage includes a body and a solid cone disposed on the body. The expansion swage further includes a deformable cone disposed on the body, wherein the solid cone is made from a first material and the deformable cone is made from a second material and wherein the deformable cone is movable relative to the body when the expansion swage is in a compliant configuration. In another aspect, a method of expanding a wellbore tubular is provided.04-15-2010
20110232900COMPLIANT EXPANSION SWAGE - The present invention generally relates to a swage assembly that is movable from a compliant configuration having a first shape to a substantially non-compliant configuration having a second shape. In one aspect, an expansion swage for expanding a wellbore tubular is provided. The expansion swage includes a body and a solid cone disposed on the body. The expansion swage further includes a deformable cone disposed on the body, wherein the solid cone is made from a first material and the deformable cone is made from a second material and wherein the deformable cone is movable relative to the body when the expansion swage is in a compliant configuration. In another aspect, a method of expanding a wellbore tubular is provided.09-29-2011
20120055683SYSTEM AND METHODS FOR TUBULAR EXPANSION - Methods and apparatus enable expanding tubing in a borehole of a hydrocarbon well. According to some embodiments, an expander device includes a collapsible swage formed of collets, at least one slip arrangement and a hydraulic jack to stroke the swage through tubing to be expanded. In operation, expanding tubing may include securing an expansion tool to the tubing, lowering the tool and tubing into a borehole, actuating a collapsible expander of the expansion tool to an extended configuration, and supplying fluid pressure to a jack coupled to the expander thereby moving the expander through the tubing which is held by at least one of first and second tubing holding devices disposed respectively ahead of the expander and behind the expander.03-08-2012

Patent applications by Mike A. Luke, Houston, TX US

Monica Luke, Littleton, MA US

Patent application numberDescriptionPublished
20120005055DYNAMIC COMPUTATION OF ROI FOR TEST AUTOMATION - Embodiments of the present invention provide a method, system and computer program product for dynamic computation of return on investment (ROI) for test automation. In an embodiment of the invention, a method for dynamic computation of ROI for test automation can include storing a development cost for an automated test tool configured to test an application under test, and also a cost of manually executing a test case for the application under test. The method also can include repeatedly executing the automated test tool for the application under test. Of note, the method can include computing a running ROI as a difference between a number of executions of the automated test tool by the cost of manually executing the test case for the application under test less the development cost of the automated test tool divided by the development cost. Finally, the method can include displaying the running ROI.01-05-2012

Paul N. Luke, Castro Valley, CA US

Patent application numberDescriptionPublished
20100102844PROXIMITY CHARGE SENSING FOR SEMICONDUCTOR DETECTORS - A non-contact charge sensor includes a semiconductor detector having a first surface and an opposing second surface. The detector includes a high resistivity electrode layer on the first surface and a low resistivity electrode on the high resistivity electrode layer. A portion of the low resistivity first surface electrode is deleted to expose the high resistivity electrode layer in a portion of the area. A low resistivity electrode layer is disposed on the second surface of the semiconductor detector. A voltage applied between the first surface low resistivity electrode and the second surface low resistivity electrode causes a free charge to drift toward the first or second surface according to a polarity of the free charge and the voltage. A charge sensitive preamplifier coupled to a non-contact electrode disposed at a distance from the exposed high resistivity electrode layer outputs a signal in response to movement of free charge within the detector.04-29-2010

Robert P. Luke, Youngsville, LA US

Patent application numberDescriptionPublished
20100277341Methods and Apparatus for Monitoring a Plurality of Worksites - Embodiments provide methods for monitoring a plurality of worksites at a facility, the methods including transporting a central monitoring station package to the facility, seating a transport container, stationing worksite monitoring equipment packages at the worksites, connecting communication links from the worksite monitoring equipment packages to central monitoring station equipment, transmitting remote transmissions from worksite monitoring equipment packages to central monitoring station equipment, displaying worksite monitoring information for a monitoring technician, and responding when remote monitoring information received from a worksite meets a response threshold criteria.11-04-2010

Scott Luke, Ben Lomond, CA US

Patent application numberDescriptionPublished
20100241138SURGICAL SYSTEM WITH ELECTRO-MECHANICAL INTERFACES TO MOUNT ROBOTIC SURGICAL ARMS - In one embodiment of the invention, a method of mounting a surgical robotic arm to a set-up arm of a robotic surgical system is provided that includes sliding a pair of guide slots of the surgical robotic arm over a pair of guide tabs in the set-up arm; aligning electrical connectors in the set-up arm to electrical connectors of the surgical robotic arm; and coincidentally mating male electrical connectors to female electrical connectors while finally mating the guide tabs in the set-up arm to flanges of a housing of the surgical robotic arm.09-23-2010

Scott Osborne Luke, Ben Lomond, CA US

Patent application numberDescriptionPublished
20090322001Spring Counterbalance with Failure Detection - A spring counterbalance mechanism balances a load with a spring. A cable has a protrusion fixed to the cable midway between two ends of the cable. The two free ends of the cable are fixedly coupled to one of the load or the spring, and a cable attachment is coupled to the remaining member. The cable passes through the cable attachment such that the protrusion is captive in the cable attachment and is movable between two stops in the cable attachment. The cable forms two segments each of which couples the spring to the load. The two segments of the cable pass over a pulley. A sensor coupled to the pulley senses rotation of the pulley allowing cable breakage to be detected by the anomalous rotation of the pulley.12-31-2009

Shawn M. Luke, Essex Junction, VT US

Patent application numberDescriptionPublished
20110153987REVERSE SIMULTANEOUS MULTI-THREADING - A multi-core processor system supporting simultaneous thread sharing across execution resources of multiple processor cores is provided. The multi-core processor system includes a first processor core with a first instruction queue and dispatch logic in communication with a first execution resource of the first processor core. The multi-core processor system also includes a second processor core with a second instruction queue and dispatch logic in communication with a second execution resource of the second processor core. A high-speed execution resource bus couples the first and second processor cores. The first instruction queue and dispatch logic is configured to issue a first instruction of a thread to the first execution resource and issue a second instruction of the thread over the high-speed execution resource bus to the second execution resource for simultaneous execution of the first and second instruction of the thread on the first and second processor cores.06-23-2011

Stanley Luke, Sunnyvale, CA US

Patent application numberDescriptionPublished
20090031096STORAGE SYSTEM AND METHOD FOR RECOVERING FROM A SYSTEM FAILURE - An apparatus and method for rapidly resuming the processing of client requests after a system failure event are disclosed. Accordingly, a surviving storage system, upon detecting a system failure event at a partner storage system, executes a takeover routine and conditions its system memory to reflect the state of the system memory of the failed storage system by processing client requests or commands stored in an operations log mirror. Then, the storage system converts the unused portion of the log mirror for use as an operations log, and resumes processing client requests prior to flushing any data to storage devices.01-29-2009

Travis C. Luke, Woodinville, WA US

Patent application numberDescriptionPublished
20080225860Distributed routing table interface - Application programming interface (API) for starting and accessing distributed routing table (DRT) functionality. The API facilitates bootstrapping into the DRT by one or more devices of a group of devices (a mesh) seeking to collaborate over a serverless connection, establishing a node of the DRT, where each node is an instance of an application that is participating in the mesh, and node participation by allowing the application to search for keys published by other nodes in the mesh, or by becoming part of the mesh by publishing a key. The API facilitates optimization of the routing table for quickly finding a root of a specific key in the mesh by finding the key directly in a cache or by asking a root node of the key that is in the local routing table that is closest numerically to the key being searched.09-18-2008

Wallace J. Luke, Pleasanton, CA US

Patent application numberDescriptionPublished
20110209205Method and System for automated emergency access to medical records - This invention is a method and a system for accessing medical records of an injured party by an emergency responder through a secure website, utilizing a portable emergency access card provided with at least one item of information of the victim, while offering safeguards for the confidentiality of the victim's information and records.08-25-2011

Wayne Douglas Luke, West Lafayette, IN US

Patent application numberDescriptionPublished
20100255106BENZOTHIOPHENES, FORMULATIONS CONTAINING SAME, AND METHODS - This invention provides compounds of formula I10-07-2010

William A. Luke, Santa Cruz, CA US

Patent application numberDescriptionPublished
20080311807MODULAR FIN FOR A SURFBOARD, SAILBOARD OR OTHER WATER-BORNE DEVICE - A fin in one embodiment includes a fin box assembly including a fin box adapted for coupling to a body portion of a water-borne device, and a fin assembly having a base member that is releasably engagable in said fin box. A fin assembly according to one embodiment includes a base member adapted for releasable engagement in a fin box that is coupled to a water-borne device, and a fin member coupled to said base member. A water-borne device in one embodiment includes a body portion, and a fin box assembly coupled to the body portion, the fin box assembly including a fin box adapted for receiving a fin assembly having a base member that is releasably engagable in said fin box.12-18-2008