Patent application number | Description | Published |
20090018179 | NOVEL CRYSTALS AND PROCESS OF MAKING 5-(-METHYL)-2-METHOXY-BENZOIC ACID - The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid. | 01-15-2009 |
20090124801 | Process for synthesizing phosphonic and phosphinic acid compounds - The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds. | 05-14-2009 |
20100145075 | PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS - The present invention is a process for the preparation of chymase modulators, useful in the treatment of inflammatory and serine protease mediated disorders. | 06-10-2010 |
20100145090 | PROCESS FOR THE PREPARATION OF PROTECTED L ALANINE DERIVATIVES - The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators. | 06-10-2010 |
20110263868 | NOVEL CRYSTALS AND PROCESS OF MAKING 5-(-METHYL)-2-METHOXY-BENZOIC ACID - The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid. | 10-27-2011 |
20120259130 | PROCESS FOR SYNTHESIZING PHOSPHONIC AND PHOSPHINIC ACID COMPOUNDS - The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds. | 10-11-2012 |
20120309986 | PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS - The present invention is a process for the preparation of chymase modulators, useful in the treatment of inflammatory and serine protease mediated disorders. | 12-06-2012 |
20130131401 | PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS - The present invention is a process for the preparation of chymase modulators, useful in the treatment of inflammatory and serine protease mediated disorders. | 05-23-2013 |
20140011851 | Novel crystals and process of making 5-(-METHYL)-2-METHOXY-BENZOIC ACID - The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid. | 01-09-2014 |
20140135525 | PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES - The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators. | 05-15-2014 |
20140221444 | Novel crystals and process of making 5-(-methyl)-2-methoxy-benzoic acid - The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid. | 08-07-2014 |
20140309413 | METHODS OF STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED NUCLEOSIDE ANALOGS - The present invention relates to the novel diastereoselective syntheses for generating phosphorothioate compounds. Examples include nucleoside phosphorothioate analogs that are useful in treating diseases and/or conditions such as viral infections. | 10-16-2014 |
20140378701 | PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES - The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators. | 12-25-2014 |